Ribosomal protein L15

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q962_LEIMA

TriTrypDb:

LmjF.26.1320 , LMJLV39_260018900 , LMJSD75_260017300

Length:

278

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	2
GO:0020023	kinetoplast	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	3
GO:0016020	membrane	2	1

Expansion

Sequence features

Q4Q962

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q962

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	193	195	PF00675	0.410
CLV_NRD_NRD_1	209	211	PF00675	0.388
CLV_NRD_NRD_1	36	38	PF00675	0.543
CLV_PCSK_FUR_1	207	211	PF00082	0.393
CLV_PCSK_KEX2_1	193	195	PF00082	0.410
CLV_PCSK_KEX2_1	204	206	PF00082	0.387
CLV_PCSK_KEX2_1	209	211	PF00082	0.388
CLV_PCSK_KEX2_1	268	270	PF00082	0.546
CLV_PCSK_PC1ET2_1	204	206	PF00082	0.387
CLV_PCSK_PC1ET2_1	268	270	PF00082	0.582
CLV_PCSK_PC7_1	189	195	PF00082	0.414
CLV_PCSK_PC7_1	205	211	PF00082	0.390
CLV_PCSK_SKI1_1	121	125	PF00082	0.628
CLV_PCSK_SKI1_1	201	205	PF00082	0.423
CLV_PCSK_SKI1_1	37	41	PF00082	0.638
DEG_APCC_DBOX_1	120	128	PF00400	0.654
DEG_APCC_DBOX_1	209	217	PF00400	0.374
DEG_Nend_UBRbox_1	1	4	PF02207	0.551
DEG_SPOP_SBC_1	112	116	PF00917	0.549
DOC_CYCLIN_yClb3_PxF_3	71	77	PF00134	0.503
DOC_MAPK_JIP1_4	121	127	PF00069	0.647
DOC_PP4_FxxP_1	87	90	PF00568	0.614
DOC_USP7_MATH_1	138	142	PF00917	0.700
DOC_USP7_MATH_1	184	188	PF00917	0.413
DOC_USP7_MATH_1	255	259	PF00917	0.501
DOC_USP7_MATH_1	47	51	PF00917	0.612
DOC_USP7_MATH_1	82	86	PF00917	0.687
DOC_USP7_MATH_1	90	94	PF00917	0.547
DOC_USP7_UBL2_3	171	175	PF12436	0.521
DOC_USP7_UBL2_3	264	268	PF12436	0.627
DOC_WW_Pin1_4	40	45	PF00397	0.689
LIG_14-3-3_CanoR_1	111	120	PF00244	0.568
LIG_14-3-3_CanoR_1	9	18	PF00244	0.685
LIG_Actin_WH2_2	218	236	PF00022	0.395
LIG_Clathr_ClatBox_1	124	128	PF01394	0.633
LIG_FHA_1	113	119	PF00498	0.501
LIG_FHA_1	34	40	PF00498	0.756
LIG_FHA_1	41	47	PF00498	0.596
LIG_FHA_2	112	118	PF00498	0.616
LIG_FHA_2	26	32	PF00498	0.684
LIG_FHA_2	84	90	PF00498	0.622
LIG_LIR_Apic_2	85	90	PF02991	0.635
LIG_LIR_Nem_3	155	160	PF02991	0.608
LIG_PDZ_Class_2	273	278	PF00595	0.479
LIG_Pex14_1	168	172	PF04695	0.402
LIG_PTB_Apo_2	215	222	PF02174	0.395
LIG_SH2_CRK	173	177	PF00017	0.394
LIG_SH2_STAT5	56	59	PF00017	0.522
LIG_SH3_3	66	72	PF00018	0.564
LIG_SUMO_SIM_par_1	122	130	PF11976	0.654
LIG_UBA3_1	229	237	PF00899	0.410
LIG_WRC_WIRS_1	105	110	PF05994	0.557
MOD_CDK_SPK_2	40	45	PF00069	0.630
MOD_CK1_1	141	147	PF00069	0.701
MOD_CK1_1	152	158	PF00069	0.515
MOD_CK1_1	23	29	PF00069	0.638
MOD_CK1_1	235	241	PF00069	0.441
MOD_CK1_1	50	56	PF00069	0.604
MOD_Cter_Amidation	266	269	PF01082	0.559
MOD_GlcNHglycan	11	14	PF01048	0.625
MOD_GlcNHglycan	144	147	PF01048	0.633
MOD_GlcNHglycan	151	154	PF01048	0.588
MOD_GlcNHglycan	258	261	PF01048	0.501
MOD_GlcNHglycan	3	6	PF01048	0.655
MOD_GlcNHglycan	30	36	PF01048	0.641
MOD_GlcNHglycan	57	60	PF01048	0.545
MOD_GlcNHglycan	92	95	PF01048	0.715
MOD_GSK3_1	112	119	PF00069	0.451
MOD_GSK3_1	138	145	PF00069	0.626
MOD_GSK3_1	256	263	PF00069	0.513
MOD_GSK3_1	267	274	PF00069	0.468
MOD_GSK3_1	33	40	PF00069	0.595
MOD_GSK3_1	90	97	PF00069	0.712
MOD_N-GLC_1	138	143	PF02516	0.689
MOD_N-GLC_1	23	28	PF02516	0.704
MOD_N-GLC_1	40	45	PF02516	0.531
MOD_N-GLC_1	50	55	PF02516	0.498
MOD_N-GLC_1	82	87	PF02516	0.636
MOD_N-GLC_2	101	103	PF02516	0.544
MOD_NEK2_1	1	6	PF00069	0.603
MOD_NEK2_1	127	132	PF00069	0.644
MOD_NEK2_1	233	238	PF00069	0.428
MOD_NEK2_1	246	251	PF00069	0.418
MOD_NEK2_2	146	151	PF00069	0.673
MOD_PIKK_1	247	253	PF00454	0.524
MOD_PKA_1	37	43	PF00069	0.539
MOD_PKA_2	256	262	PF00069	0.526
MOD_PKB_1	109	117	PF00069	0.575
MOD_PKB_1	269	277	PF00069	0.482
MOD_Plk_1	116	122	PF00069	0.584
MOD_Plk_1	138	144	PF00069	0.587
MOD_Plk_1	50	56	PF00069	0.604
MOD_Plk_4	138	144	PF00069	0.504
MOD_Plk_4	83	89	PF00069	0.540
MOD_ProDKin_1	40	46	PF00069	0.687
TRG_DiLeu_BaLyEn_6	119	124	PF01217	0.634
TRG_ENDOCYTIC_2	157	160	PF00928	0.580
TRG_ENDOCYTIC_2	173	176	PF00928	0.291
TRG_ER_diArg_1	108	111	PF00400	0.545
TRG_ER_diArg_1	193	195	PF00400	0.410
TRG_ER_diArg_1	208	210	PF00400	0.239
TRG_ER_diArg_1	269	272	PF00400	0.498
TRG_ER_diLys_1	273	278	PF00400	0.472
TRG_NLS_Bipartite_1	193	208	PF00514	0.395
TRG_NLS_MonoExtC_3	267	272	PF00514	0.624
TRG_NLS_MonoExtN_4	201	208	PF00514	0.420
TRG_NLS_MonoExtN_4	266	272	PF00514	0.627

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC03	Leptomonas seymouri	65%	100%
A0A1X0NS69	Trypanosomatidae	62%	100%
A0A3R7ND13	Trypanosoma rangeli	61%	100%
A0A3S7WZU2	Leishmania donovani	92%	100%
A4HEY7	Leishmania braziliensis	78%	100%
A4I261	Leishmania infantum	92%	100%
C9ZRT8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	100%
E9AYB1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
V5BIT0	Trypanosoma cruzi	62%	91%