Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q927_LEIMA

TriTrypDb:

LmjF.26.1665 , LMJLV39_260022800 , LMJSD75_260021200

Length:

263

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q927

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q927

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	200	204	PF00656	0.463
CLV_C14_Caspase3-7	242	246	PF00656	0.473
CLV_NRD_NRD_1	109	111	PF00675	0.335
CLV_NRD_NRD_1	118	120	PF00675	0.356
CLV_NRD_NRD_1	131	133	PF00675	0.438
CLV_NRD_NRD_1	135	137	PF00675	0.362
CLV_NRD_NRD_1	260	262	PF00675	0.607
CLV_NRD_NRD_1	83	85	PF00675	0.446
CLV_NRD_NRD_1	97	99	PF00675	0.313
CLV_PCSK_KEX2_1	109	111	PF00082	0.335
CLV_PCSK_KEX2_1	131	133	PF00082	0.574
CLV_PCSK_KEX2_1	135	137	PF00082	0.580
CLV_PCSK_KEX2_1	260	262	PF00082	0.607
CLV_PCSK_KEX2_1	83	85	PF00082	0.446
CLV_PCSK_KEX2_1	97	99	PF00082	0.313
CLV_PCSK_PC7_1	131	137	PF00082	0.497
CLV_PCSK_SKI1_1	16	20	PF00082	0.487
CLV_PCSK_SKI1_1	253	257	PF00082	0.441
CLV_PCSK_SKI1_1	63	67	PF00082	0.406
CLV_PCSK_SKI1_1	91	95	PF00082	0.446
DOC_MAPK_gen_1	100	108	PF00069	0.384
DOC_MAPK_gen_1	109	117	PF00069	0.310
DOC_MAPK_MEF2A_6	16	24	PF00069	0.578
DOC_MAPK_MEF2A_6	163	171	PF00069	0.344
DOC_MAPK_MEF2A_6	63	72	PF00069	0.385
DOC_USP7_MATH_1	215	219	PF00917	0.568
DOC_WW_Pin1_4	16	21	PF00397	0.567
DOC_WW_Pin1_4	218	223	PF00397	0.581
DOC_WW_Pin1_4	230	235	PF00397	0.550
LIG_14-3-3_CanoR_1	135	142	PF00244	0.405
LIG_14-3-3_CanoR_1	239	247	PF00244	0.488
LIG_14-3-3_CanoR_1	8	15	PF00244	0.452
LIG_BIR_II_1	1	5	PF00653	0.466
LIG_CaM_NSCaTE_8	21	28	PF13499	0.404
LIG_FHA_1	154	160	PF00498	0.383
LIG_FHA_1	164	170	PF00498	0.411
LIG_FHA_1	17	23	PF00498	0.569
LIG_FHA_1	185	191	PF00498	0.376
LIG_FHA_2	231	237	PF00498	0.744
LIG_LIR_Gen_1	19	28	PF02991	0.505
LIG_LIR_Gen_1	46	55	PF02991	0.495
LIG_LIR_Nem_3	19	24	PF02991	0.575
LIG_LIR_Nem_3	203	208	PF02991	0.530
LIG_LIR_Nem_3	244	250	PF02991	0.490
LIG_LIR_Nem_3	46	52	PF02991	0.491
LIG_NRP_CendR_1	260	263	PF00754	0.548
LIG_REV1ctd_RIR_1	105	114	PF16727	0.329
LIG_RPA_C_Fungi	107	119	PF08784	0.358
LIG_SH2_CRK	67	71	PF00017	0.409
LIG_SH2_NCK_1	122	126	PF00017	0.457
LIG_SH2_STAT5	154	157	PF00017	0.477
LIG_SH2_STAT5	205	208	PF00017	0.465
LIG_SH2_STAT5	33	36	PF00017	0.557
LIG_SH3_1	220	226	PF00018	0.528
LIG_SH3_3	219	225	PF00018	0.587
LIG_SH3_CIN85_PxpxPR_1	226	231	PF14604	0.546
LIG_SUMO_SIM_par_1	186	191	PF11976	0.327
LIG_SUMO_SIM_par_1	41	48	PF11976	0.405
LIG_TYR_ITIM	65	70	PF00017	0.401
MOD_CK1_1	218	224	PF00069	0.623
MOD_CK1_1	243	249	PF00069	0.525
MOD_CK1_1	44	50	PF00069	0.395
MOD_CK2_1	230	236	PF00069	0.543
MOD_GlcNHglycan	137	140	PF01048	0.432
MOD_GlcNHglycan	142	145	PF01048	0.339
MOD_GlcNHglycan	190	193	PF01048	0.363
MOD_GlcNHglycan	217	220	PF01048	0.543
MOD_GlcNHglycan	226	229	PF01048	0.653
MOD_GlcNHglycan	26	29	PF01048	0.406
MOD_GSK3_1	184	191	PF00069	0.325
MOD_GSK3_1	197	204	PF00069	0.580
MOD_GSK3_1	239	246	PF00069	0.687
MOD_GSK3_1	41	48	PF00069	0.488
MOD_GSK3_1	87	94	PF00069	0.369
MOD_NEK2_1	108	113	PF00069	0.377
MOD_NEK2_1	23	28	PF00069	0.422
MOD_NEK2_1	43	48	PF00069	0.376
MOD_NEK2_1	66	71	PF00069	0.536
MOD_NEK2_1	92	97	PF00069	0.520
MOD_PKA_1	135	141	PF00069	0.438
MOD_PKA_2	108	114	PF00069	0.389
MOD_PKA_2	135	141	PF00069	0.528
MOD_PKA_2	7	13	PF00069	0.484
MOD_PKA_2	96	102	PF00069	0.356
MOD_Plk_4	184	190	PF00069	0.443
MOD_Plk_4	201	207	PF00069	0.482
MOD_Plk_4	26	32	PF00069	0.429
MOD_ProDKin_1	16	22	PF00069	0.567
MOD_ProDKin_1	218	224	PF00069	0.582
MOD_ProDKin_1	230	236	PF00069	0.548
TRG_ENDOCYTIC_2	247	250	PF00928	0.476
TRG_ENDOCYTIC_2	67	70	PF00928	0.470
TRG_ER_diArg_1	108	110	PF00400	0.299
TRG_ER_diArg_1	260	263	PF00400	0.632
TRG_ER_diArg_1	97	100	PF00400	0.436

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I008	Leptomonas seymouri	37%	100%
A0A3S7WZY2	Leishmania donovani	90%	100%
A4I2A1	Leishmania infantum	89%	100%
E9AYE6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%