Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q915_LEIMA

TriTrypDb:

LmjF.26.1755 , LMJLV39_260024000 , LMJSD75_260022500

Length:

381

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q915

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q915

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	105	109	PF00656	0.820
CLV_C14_Caspase3-7	158	162	PF00656	0.751
CLV_NRD_NRD_1	210	212	PF00675	0.660
CLV_NRD_NRD_1	316	318	PF00675	0.776
CLV_NRD_NRD_1	373	375	PF00675	0.754
CLV_NRD_NRD_1	76	78	PF00675	0.746
CLV_PCSK_FUR_1	208	212	PF00082	0.654
CLV_PCSK_FUR_1	314	318	PF00082	0.772
CLV_PCSK_KEX2_1	210	212	PF00082	0.660
CLV_PCSK_KEX2_1	314	316	PF00082	0.773
CLV_PCSK_KEX2_1	373	375	PF00082	0.754
CLV_PCSK_KEX2_1	75	77	PF00082	0.748
CLV_PCSK_PC7_1	311	317	PF00082	0.765
CLV_PCSK_SKI1_1	210	214	PF00082	0.641
DEG_SPOP_SBC_1	137	141	PF00917	0.743
DEG_SPOP_SBC_1	298	302	PF00917	0.751
DOC_CYCLIN_RxL_1	207	217	PF00134	0.646
DOC_CYCLIN_RxL_1	218	226	PF00134	0.508
DOC_PP1_RVXF_1	219	226	PF00149	0.689
DOC_USP7_MATH_1	132	136	PF00917	0.677
DOC_USP7_MATH_1	236	240	PF00917	0.772
DOC_USP7_MATH_1	26	30	PF00917	0.789
DOC_USP7_MATH_1	298	302	PF00917	0.751
DOC_USP7_MATH_1	35	39	PF00917	0.733
DOC_USP7_MATH_1	361	365	PF00917	0.555
DOC_USP7_MATH_1	55	59	PF00917	0.521
DOC_WW_Pin1_4	12	17	PF00397	0.835
DOC_WW_Pin1_4	139	144	PF00397	0.798
DOC_WW_Pin1_4	214	219	PF00397	0.586
DOC_WW_Pin1_4	27	32	PF00397	0.586
DOC_WW_Pin1_4	294	299	PF00397	0.723
LIG_14-3-3_CanoR_1	210	220	PF00244	0.599
LIG_14-3-3_CanoR_1	316	322	PF00244	0.772
LIG_14-3-3_CanoR_1	79	88	PF00244	0.727
LIG_BIR_II_1	1	5	PF00653	0.842
LIG_BIR_III_4	83	87	PF00653	0.714
LIG_Clathr_ClatBox_1	222	226	PF01394	0.619
LIG_CSL_BTD_1	191	194	PF09270	0.671
LIG_FHA_1	118	124	PF00498	0.710
LIG_FHA_1	140	146	PF00498	0.604
LIG_FHA_1	184	190	PF00498	0.692
LIG_FHA_1	52	58	PF00498	0.817
LIG_FHA_2	103	109	PF00498	0.784
LIG_FHA_2	37	43	PF00498	0.765
LIG_LIR_Apic_2	337	343	PF02991	0.699
LIG_LIR_Gen_1	328	338	PF02991	0.708
LIG_LIR_Nem_3	217	223	PF02991	0.517
LIG_LIR_Nem_3	300	306	PF02991	0.706
LIG_LIR_Nem_3	328	334	PF02991	0.714
LIG_PDZ_Class_3	376	381	PF00595	0.754
LIG_Rb_LxCxE_1	174	190	PF01857	0.768
LIG_SH2_CRK	331	335	PF00017	0.638
LIG_SH2_CRK	340	344	PF00017	0.656
LIG_SH2_NCK_1	331	335	PF00017	0.638
LIG_SH2_STAT5	357	360	PF00017	0.699
LIG_SH3_3	230	236	PF00018	0.778
LIG_TRAF2_1	39	42	PF00917	0.726
MOD_CDC14_SPxK_1	15	18	PF00782	0.831
MOD_CDK_SPK_2	27	32	PF00069	0.756
MOD_CDK_SPxK_1	12	18	PF00069	0.835
MOD_CDK_SPxxK_3	214	221	PF00069	0.588
MOD_CK1_1	136	142	PF00069	0.738
MOD_CK1_1	157	163	PF00069	0.640
MOD_CK1_1	2	8	PF00069	0.758
MOD_CK1_1	294	300	PF00069	0.617
MOD_CK1_1	330	336	PF00069	0.708
MOD_CK1_1	58	64	PF00069	0.622
MOD_CK1_1	82	88	PF00069	0.787
MOD_CK1_1	93	99	PF00069	0.692
MOD_CK2_1	132	138	PF00069	0.617
MOD_CK2_1	141	147	PF00069	0.644
MOD_CK2_1	157	163	PF00069	0.597
MOD_CK2_1	236	242	PF00069	0.630
MOD_CK2_1	317	323	PF00069	0.777
MOD_CK2_1	35	41	PF00069	0.762
MOD_CK2_1	58	64	PF00069	0.700
MOD_GlcNHglycan	1	4	PF01048	0.843
MOD_GlcNHglycan	108	112	PF01048	0.785
MOD_GlcNHglycan	135	138	PF01048	0.751
MOD_GlcNHglycan	169	172	PF01048	0.700
MOD_GlcNHglycan	238	241	PF01048	0.751
MOD_GlcNHglycan	293	296	PF01048	0.619
MOD_GlcNHglycan	345	348	PF01048	0.686
MOD_GlcNHglycan	361	364	PF01048	0.509
MOD_GlcNHglycan	374	377	PF01048	0.595
MOD_GlcNHglycan	60	63	PF01048	0.693
MOD_GlcNHglycan	83	87	PF01048	0.831
MOD_GSK3_1	109	116	PF00069	0.512
MOD_GSK3_1	117	124	PF00069	0.740
MOD_GSK3_1	132	139	PF00069	0.631
MOD_GSK3_1	163	170	PF00069	0.657
MOD_GSK3_1	174	181	PF00069	0.670
MOD_GSK3_1	183	190	PF00069	0.431
MOD_GSK3_1	192	199	PF00069	0.362
MOD_GSK3_1	294	301	PF00069	0.735
MOD_GSK3_1	33	40	PF00069	0.626
MOD_GSK3_1	51	58	PF00069	0.655
MOD_GSK3_1	90	97	PF00069	0.828
MOD_N-GLC_1	102	107	PF02516	0.593
MOD_N-GLC_1	121	126	PF02516	0.501
MOD_N-GLC_1	163	168	PF02516	0.789
MOD_NEK2_1	1	6	PF00069	0.841
MOD_NEK2_1	154	159	PF00069	0.599
MOD_NEK2_1	257	262	PF00069	0.696
MOD_NEK2_1	299	304	PF00069	0.755
MOD_PIKK_1	117	123	PF00454	0.713
MOD_PIKK_1	192	198	PF00454	0.660
MOD_PKA_2	372	378	PF00069	0.749
MOD_PKA_2	94	100	PF00069	0.756
MOD_PKB_1	315	323	PF00069	0.771
MOD_PKB_1	77	85	PF00069	0.754
MOD_Plk_1	163	169	PF00069	0.710
MOD_Plk_1	338	344	PF00069	0.683
MOD_Plk_2-3	102	108	PF00069	0.632
MOD_Plk_2-3	37	43	PF00069	0.726
MOD_Plk_4	141	147	PF00069	0.719
MOD_Plk_4	187	193	PF00069	0.644
MOD_ProDKin_1	12	18	PF00069	0.835
MOD_ProDKin_1	139	145	PF00069	0.800
MOD_ProDKin_1	214	220	PF00069	0.581
MOD_ProDKin_1	27	33	PF00069	0.586
MOD_ProDKin_1	294	300	PF00069	0.722
TRG_DiLeu_BaLyEn_6	208	213	PF01217	0.643
TRG_DiLeu_BaLyEn_6	218	223	PF01217	0.518
TRG_ENDOCYTIC_2	219	222	PF00928	0.520
TRG_ENDOCYTIC_2	306	309	PF00928	0.755
TRG_ENDOCYTIC_2	331	334	PF00928	0.672
TRG_ER_diArg_1	210	212	PF00400	0.660
TRG_ER_diArg_1	313	316	PF00400	0.766
TRG_ER_diArg_1	75	77	PF00400	0.748
TRG_Pf-PMV_PEXEL_1	221	226	PF00026	0.525

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICW3	Leishmania donovani	87%	100%
A4I2B0	Leishmania infantum	88%	100%
E9AIQ9	Leishmania braziliensis	62%	100%
E9AYF6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%