Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q914_LEIMA

TriTrypDb:

LmjF.26.1780 , LMJLV39_260024100 , LMJSD75_260022600

Length:

212

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q914

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q914

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	137	141	PF00656	0.659
CLV_C14_Caspase3-7	19	23	PF00656	0.480
CLV_C14_Caspase3-7	66	70	PF00656	0.576
CLV_NRD_NRD_1	150	152	PF00675	0.583
CLV_NRD_NRD_1	51	53	PF00675	0.574
CLV_PCSK_FUR_1	117	121	PF00082	0.524
CLV_PCSK_KEX2_1	119	121	PF00082	0.522
CLV_PCSK_KEX2_1	150	152	PF00082	0.656
CLV_PCSK_PC1ET2_1	119	121	PF00082	0.560
CLV_PCSK_SKI1_1	21	25	PF00082	0.602
CLV_PCSK_SKI1_1	53	57	PF00082	0.636
DOC_WW_Pin1_4	1	6	PF00397	0.787
DOC_WW_Pin1_4	7	12	PF00397	0.602
DOC_WW_Pin1_4	75	80	PF00397	0.715
LIG_Clathr_ClatBox_1	133	137	PF01394	0.541
LIG_Clathr_ClatBox_1	143	147	PF01394	0.555
LIG_FHA_1	165	171	PF00498	0.651
LIG_FHA_1	2	8	PF00498	0.699
LIG_FHA_1	27	33	PF00498	0.520
LIG_FHA_1	81	87	PF00498	0.624
LIG_FHA_2	64	70	PF00498	0.758
LIG_FHA_2	92	98	PF00498	0.791
LIG_Integrin_RGD_1	164	166	PF01839	0.581
LIG_IRF3_LxIS_1	72	78	PF10401	0.567
LIG_LIR_Apic_2	34	40	PF02991	0.501
LIG_PCNA_PIPBox_1	126	135	PF02747	0.603
LIG_PCNA_yPIPBox_3	119	133	PF02747	0.606
LIG_PCNA_yPIPBox_3	21	32	PF02747	0.566
LIG_SH2_CRK	37	41	PF00017	0.631
LIG_SH2_NCK_1	37	41	PF00017	0.548
LIG_SH2_SRC	132	135	PF00017	0.598
LIG_SH2_STAP1	198	202	PF00017	0.547
LIG_SH2_STAT5	132	135	PF00017	0.598
LIG_SH3_3	5	11	PF00018	0.706
LIG_SUMO_SIM_par_1	132	140	PF11976	0.648
LIG_TRAF2_1	176	179	PF00917	0.664
LIG_TRAF2_1	23	26	PF00917	0.446
MOD_CK1_1	15	21	PF00069	0.650
MOD_CK2_1	6	12	PF00069	0.712
MOD_CK2_1	91	97	PF00069	0.792
MOD_GSK3_1	132	139	PF00069	0.510
MOD_GSK3_1	26	33	PF00069	0.544
MOD_GSK3_1	73	80	PF00069	0.629
MOD_NEK2_1	153	158	PF00069	0.610
MOD_NEK2_1	91	96	PF00069	0.731
MOD_NMyristoyl	1	7	PF02799	0.701
MOD_PIKK_1	182	188	PF00454	0.590
MOD_PKA_2	73	79	PF00069	0.709
MOD_Plk_4	32	38	PF00069	0.541
MOD_Plk_4	81	87	PF00069	0.545
MOD_ProDKin_1	1	7	PF00069	0.789
MOD_ProDKin_1	75	81	PF00069	0.712
MOD_SUMO_rev_2	63	73	PF00179	0.706
TRG_DiLeu_BaEn_1	190	195	PF01217	0.658
TRG_ENDOCYTIC_2	121	124	PF00928	0.634
TRG_ER_diArg_1	149	151	PF00400	0.651
TRG_Pf-PMV_PEXEL_1	111	115	PF00026	0.657
TRG_Pf-PMV_PEXEL_1	122	126	PF00026	0.445

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6B4	Leptomonas seymouri	37%	93%
A0A3S7X005	Leishmania donovani	90%	100%
A4HD51	Leishmania braziliensis	72%	100%
A4I2B1	Leishmania infantum	90%	100%