Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q908_LEIMA

TriTrypDb:

LmjF.26.1840 , LMJLV39_260024800 , LMJSD75_260023300

Length:

992

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q908

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q908

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	301	305	PF00656	0.783
CLV_MEL_PAP_1	853	859	PF00089	0.605
CLV_NRD_NRD_1	177	179	PF00675	0.628
CLV_NRD_NRD_1	203	205	PF00675	0.677
CLV_NRD_NRD_1	431	433	PF00675	0.815
CLV_NRD_NRD_1	518	520	PF00675	0.795
CLV_NRD_NRD_1	53	55	PF00675	0.722
CLV_NRD_NRD_1	768	770	PF00675	0.712
CLV_NRD_NRD_1	913	915	PF00675	0.683
CLV_NRD_NRD_1	936	938	PF00675	0.579
CLV_PCSK_KEX2_1	177	179	PF00082	0.628
CLV_PCSK_KEX2_1	431	433	PF00082	0.819
CLV_PCSK_KEX2_1	53	55	PF00082	0.722
CLV_PCSK_KEX2_1	768	770	PF00082	0.712
CLV_PCSK_KEX2_1	913	915	PF00082	0.683
CLV_PCSK_KEX2_1	936	938	PF00082	0.579
CLV_PCSK_SKI1_1	178	182	PF00082	0.751
CLV_PCSK_SKI1_1	208	212	PF00082	0.679
CLV_PCSK_SKI1_1	308	312	PF00082	0.826
CLV_PCSK_SKI1_1	417	421	PF00082	0.607
CLV_PCSK_SKI1_1	481	485	PF00082	0.504
CLV_PCSK_SKI1_1	519	523	PF00082	0.794
CLV_PCSK_SKI1_1	530	534	PF00082	0.619
CLV_PCSK_SKI1_1	611	615	PF00082	0.807
CLV_PCSK_SKI1_1	781	785	PF00082	0.734
DEG_Nend_UBRbox_2	1	3	PF02207	0.632
DEG_SCF_FBW7_2	947	954	PF00400	0.800
DEG_SPOP_SBC_1	433	437	PF00917	0.728
DEG_SPOP_SBC_1	465	469	PF00917	0.709
DEG_SPOP_SBC_1	861	865	PF00917	0.715
DOC_ANK_TNKS_1	343	350	PF00023	0.748
DOC_CYCLIN_yCln2_LP_2	203	209	PF00134	0.754
DOC_CYCLIN_yCln2_LP_2	80	86	PF00134	0.714
DOC_CYCLIN_yCln2_LP_2	895	901	PF00134	0.716
DOC_MAPK_MEF2A_6	402	411	PF00069	0.758
DOC_MAPK_MEF2A_6	748	755	PF00069	0.726
DOC_PP1_RVXF_1	415	421	PF00149	0.730
DOC_PP2B_LxvP_1	294	297	PF13499	0.785
DOC_PP2B_LxvP_1	533	536	PF13499	0.794
DOC_PP2B_LxvP_1	80	83	PF13499	0.758
DOC_PP2B_LxvP_1	93	96	PF13499	0.562
DOC_PP2B_PxIxI_1	868	874	PF00149	0.779
DOC_PP4_FxxP_1	633	636	PF00568	0.744
DOC_SPAK_OSR1_1	856	860	PF12202	0.650
DOC_USP7_MATH_1	106	110	PF00917	0.629
DOC_USP7_MATH_1	209	213	PF00917	0.638
DOC_USP7_MATH_1	252	256	PF00917	0.644
DOC_USP7_MATH_1	26	30	PF00917	0.583
DOC_USP7_MATH_1	288	292	PF00917	0.804
DOC_USP7_MATH_1	303	307	PF00917	0.575
DOC_USP7_MATH_1	372	376	PF00917	0.787
DOC_USP7_MATH_1	433	437	PF00917	0.728
DOC_USP7_MATH_1	464	468	PF00917	0.717
DOC_USP7_MATH_1	52	56	PF00917	0.719
DOC_USP7_MATH_1	538	542	PF00917	0.664
DOC_USP7_MATH_1	568	572	PF00917	0.785
DOC_USP7_MATH_1	606	610	PF00917	0.726
DOC_USP7_MATH_1	676	680	PF00917	0.726
DOC_USP7_MATH_1	708	712	PF00917	0.678
DOC_USP7_MATH_1	838	842	PF00917	0.818
DOC_USP7_MATH_1	84	88	PF00917	0.751
DOC_USP7_MATH_1	861	865	PF00917	0.610
DOC_USP7_MATH_1	957	961	PF00917	0.603
DOC_WW_Pin1_4	120	125	PF00397	0.776
DOC_WW_Pin1_4	186	191	PF00397	0.710
DOC_WW_Pin1_4	261	266	PF00397	0.850
DOC_WW_Pin1_4	373	378	PF00397	0.811
DOC_WW_Pin1_4	434	439	PF00397	0.834
DOC_WW_Pin1_4	492	497	PF00397	0.673
DOC_WW_Pin1_4	564	569	PF00397	0.755
DOC_WW_Pin1_4	586	591	PF00397	0.810
DOC_WW_Pin1_4	632	637	PF00397	0.705
DOC_WW_Pin1_4	70	75	PF00397	0.603
DOC_WW_Pin1_4	786	791	PF00397	0.813
DOC_WW_Pin1_4	807	812	PF00397	0.667
DOC_WW_Pin1_4	830	835	PF00397	0.734
DOC_WW_Pin1_4	836	841	PF00397	0.667
DOC_WW_Pin1_4	947	952	PF00397	0.767
LIG_14-3-3_CanoR_1	177	183	PF00244	0.748
LIG_14-3-3_CanoR_1	208	217	PF00244	0.651
LIG_14-3-3_CanoR_1	340	348	PF00244	0.785
LIG_14-3-3_CanoR_1	431	441	PF00244	0.831
LIG_14-3-3_CanoR_1	781	790	PF00244	0.735
LIG_14-3-3_CanoR_1	936	944	PF00244	0.567
LIG_14-3-3_CanoR_1	972	976	PF00244	0.572
LIG_APCC_ABBAyCdc20_2	308	314	PF00400	0.819
LIG_BRCT_BRCA1_1	476	480	PF00533	0.537
LIG_BRCT_BRCA1_1	664	668	PF00533	0.734
LIG_BRCT_BRCA1_1	941	945	PF00533	0.700
LIG_deltaCOP1_diTrp_1	976	986	PF00928	0.697
LIG_EVH1_1	294	298	PF00568	0.785
LIG_FHA_1	137	143	PF00498	0.767
LIG_FHA_1	254	260	PF00498	0.739
LIG_FHA_1	374	380	PF00498	0.672
LIG_FHA_1	578	584	PF00498	0.651
LIG_FHA_1	669	675	PF00498	0.669
LIG_FHA_1	889	895	PF00498	0.660
LIG_FHA_1	903	909	PF00498	0.407
LIG_FHA_1	926	932	PF00498	0.726
LIG_FHA_1	948	954	PF00498	0.745
LIG_FHA_2	187	193	PF00498	0.540
LIG_FHA_2	276	282	PF00498	0.664
LIG_FHA_2	31	37	PF00498	0.553
LIG_FHA_2	43	49	PF00498	0.488
LIG_FHA_2	466	472	PF00498	0.629
LIG_FHA_2	545	551	PF00498	0.818
LIG_FHA_2	744	750	PF00498	0.771
LIG_FHA_2	782	788	PF00498	0.743
LIG_FHA_2	841	847	PF00498	0.781
LIG_FHA_2	863	869	PF00498	0.782
LIG_FHA_2	971	977	PF00498	0.601
LIG_Integrin_isoDGR_2	415	417	PF01839	0.740
LIG_LIR_Gen_1	225	235	PF02991	0.741
LIG_LIR_Gen_1	799	807	PF02991	0.763
LIG_LIR_LC3C_4	750	755	PF02991	0.716
LIG_LIR_Nem_3	192	197	PF02991	0.684
LIG_LIR_Nem_3	2	7	PF02991	0.592
LIG_LIR_Nem_3	225	231	PF02991	0.733
LIG_LIR_Nem_3	421	425	PF02991	0.623
LIG_LIR_Nem_3	477	483	PF02991	0.528
LIG_LIR_Nem_3	730	736	PF02991	0.732
LIG_LIR_Nem_3	799	803	PF02991	0.799
LIG_LIR_Nem_3	905	909	PF02991	0.647
LIG_LIR_Nem_3	99	104	PF02991	0.687
LIG_PDZ_Class_2	987	992	PF00595	0.639
LIG_Pex14_1	986	990	PF04695	0.634
LIG_SH2_CRK	488	492	PF00017	0.743
LIG_SH2_CRK	800	804	PF00017	0.764
LIG_SH2_CRK	916	920	PF00017	0.545
LIG_SH2_GRB2like	526	529	PF00017	0.791
LIG_SH2_STAP1	911	915	PF00017	0.665
LIG_SH2_STAT5	167	170	PF00017	0.752
LIG_SH2_STAT5	526	529	PF00017	0.791
LIG_SH2_STAT5	734	737	PF00017	0.578
LIG_SH3_1	262	268	PF00018	0.791
LIG_SH3_1	292	298	PF00018	0.789
LIG_SH3_3	126	132	PF00018	0.766
LIG_SH3_3	262	268	PF00018	0.748
LIG_SH3_3	292	298	PF00018	0.673
LIG_SH3_3	380	386	PF00018	0.821
LIG_SH3_3	539	545	PF00018	0.811
LIG_SH3_3	584	590	PF00018	0.751
LIG_SH3_3	602	608	PF00018	0.499
LIG_SH3_3	898	904	PF00018	0.707
LIG_SH3_3	916	922	PF00018	0.408
LIG_Sin3_3	28	35	PF02671	0.592
LIG_SUMO_SIM_anti_2	891	897	PF11976	0.671
LIG_SUMO_SIM_par_1	405	410	PF11976	0.756
LIG_TRAF2_1	848	851	PF00917	0.814
LIG_TRFH_1	235	239	PF08558	0.762
LIG_TYR_ITIM	310	315	PF00017	0.808
LIG_UBA3_1	197	205	PF00899	0.545
LIG_WW_1	438	441	PF00397	0.620
LIG_WW_3	437	441	PF00397	0.659
MOD_CDC14_SPxK_1	437	440	PF00782	0.782
MOD_CDK_SPxK_1	434	440	PF00069	0.776
MOD_CDK_SPxxK_3	120	127	PF00069	0.777
MOD_CDK_SPxxK_3	830	837	PF00069	0.650
MOD_CK1_1	105	111	PF00069	0.542
MOD_CK1_1	114	120	PF00069	0.672
MOD_CK1_1	136	142	PF00069	0.679
MOD_CK1_1	145	151	PF00069	0.612
MOD_CK1_1	163	169	PF00069	0.510
MOD_CK1_1	270	276	PF00069	0.863
MOD_CK1_1	327	333	PF00069	0.680
MOD_CK1_1	364	370	PF00069	0.813
MOD_CK1_1	460	466	PF00069	0.833
MOD_CK1_1	495	501	PF00069	0.639
MOD_CK1_1	571	577	PF00069	0.780
MOD_CK1_1	589	595	PF00069	0.530
MOD_CK1_1	626	632	PF00069	0.809
MOD_CK1_1	693	699	PF00069	0.594
MOD_CK1_1	711	717	PF00069	0.521
MOD_CK1_1	720	726	PF00069	0.638
MOD_CK1_1	841	847	PF00069	0.834
MOD_CK1_1	89	95	PF00069	0.744
MOD_CK1_1	938	944	PF00069	0.742
MOD_CK2_1	186	192	PF00069	0.707
MOD_CK2_1	275	281	PF00069	0.794
MOD_CK2_1	30	36	PF00069	0.553
MOD_CK2_1	42	48	PF00069	0.483
MOD_CK2_1	465	471	PF00069	0.641
MOD_CK2_1	52	58	PF00069	0.635
MOD_CK2_1	743	749	PF00069	0.777
MOD_CK2_1	781	787	PF00069	0.775
MOD_CK2_1	830	836	PF00069	0.793
MOD_CK2_1	845	851	PF00069	0.638
MOD_CK2_1	970	976	PF00069	0.597
MOD_CMANNOS	500	503	PF00535	0.778
MOD_Cter_Amidation	934	937	PF01082	0.544
MOD_GlcNHglycan	104	107	PF01048	0.551
MOD_GlcNHglycan	108	111	PF01048	0.508
MOD_GlcNHglycan	136	139	PF01048	0.719
MOD_GlcNHglycan	163	166	PF01048	0.746
MOD_GlcNHglycan	168	171	PF01048	0.680
MOD_GlcNHglycan	269	272	PF01048	0.675
MOD_GlcNHglycan	368	371	PF01048	0.784
MOD_GlcNHglycan	38	42	PF01048	0.586
MOD_GlcNHglycan	383	386	PF01048	0.650
MOD_GlcNHglycan	412	415	PF01048	0.575
MOD_GlcNHglycan	449	452	PF01048	0.658
MOD_GlcNHglycan	462	465	PF01048	0.708
MOD_GlcNHglycan	536	539	PF01048	0.803
MOD_GlcNHglycan	54	57	PF01048	0.551
MOD_GlcNHglycan	542	545	PF01048	0.716
MOD_GlcNHglycan	561	565	PF01048	0.684
MOD_GlcNHglycan	568	571	PF01048	0.708
MOD_GlcNHglycan	573	576	PF01048	0.624
MOD_GlcNHglycan	608	611	PF01048	0.764
MOD_GlcNHglycan	62	66	PF01048	0.663
MOD_GlcNHglycan	664	667	PF01048	0.722
MOD_GlcNHglycan	678	681	PF01048	0.598
MOD_GlcNHglycan	721	725	PF01048	0.746
MOD_GlcNHglycan	781	784	PF01048	0.729
MOD_GlcNHglycan	794	797	PF01048	0.589
MOD_GlcNHglycan	88	91	PF01048	0.734
MOD_GSK3_1	102	109	PF00069	0.520
MOD_GSK3_1	133	140	PF00069	0.697
MOD_GSK3_1	145	152	PF00069	0.593
MOD_GSK3_1	153	160	PF00069	0.496
MOD_GSK3_1	26	33	PF00069	0.587
MOD_GSK3_1	263	270	PF00069	0.845
MOD_GSK3_1	298	305	PF00069	0.786
MOD_GSK3_1	324	331	PF00069	0.775
MOD_GSK3_1	351	358	PF00069	0.742
MOD_GSK3_1	361	368	PF00069	0.748
MOD_GSK3_1	381	388	PF00069	0.558
MOD_GSK3_1	439	446	PF00069	0.676
MOD_GSK3_1	447	454	PF00069	0.707
MOD_GSK3_1	460	467	PF00069	0.694
MOD_GSK3_1	470	477	PF00069	0.552
MOD_GSK3_1	534	541	PF00069	0.603
MOD_GSK3_1	560	567	PF00069	0.775
MOD_GSK3_1	571	578	PF00069	0.635
MOD_GSK3_1	582	589	PF00069	0.590
MOD_GSK3_1	61	68	PF00069	0.645
MOD_GSK3_1	664	671	PF00069	0.789
MOD_GSK3_1	672	679	PF00069	0.671
MOD_GSK3_1	713	720	PF00069	0.758
MOD_GSK3_1	781	788	PF00069	0.803
MOD_GSK3_1	792	799	PF00069	0.647
MOD_GSK3_1	836	843	PF00069	0.842
MOD_GSK3_1	85	92	PF00069	0.750
MOD_GSK3_1	931	938	PF00069	0.633
MOD_GSK3_1	939	946	PF00069	0.533
MOD_GSK3_1	970	977	PF00069	0.633
MOD_LATS_1	338	344	PF00433	0.735
MOD_N-GLC_1	102	107	PF02516	0.704
MOD_N-GLC_1	142	147	PF02516	0.761
MOD_N-GLC_1	149	154	PF02516	0.681
MOD_N-GLC_1	381	386	PF02516	0.776
MOD_N-GLC_1	626	631	PF02516	0.808
MOD_N-GLC_1	708	713	PF02516	0.660
MOD_N-GLC_1	807	812	PF02516	0.604
MOD_NEK2_1	102	107	PF00069	0.517
MOD_NEK2_1	142	147	PF00069	0.645
MOD_NEK2_1	161	166	PF00069	0.635
MOD_NEK2_1	30	35	PF00069	0.593
MOD_NEK2_1	328	333	PF00069	0.794
MOD_NEK2_1	458	463	PF00069	0.772
MOD_NEK2_1	554	559	PF00069	0.760
MOD_NEK2_1	625	630	PF00069	0.582
MOD_NEK2_1	645	650	PF00069	0.712
MOD_NEK2_1	66	71	PF00069	0.766
MOD_NEK2_1	668	673	PF00069	0.734
MOD_NEK2_1	674	679	PF00069	0.663
MOD_NEK2_1	690	695	PF00069	0.677
MOD_NEK2_1	779	784	PF00069	0.709
MOD_NEK2_1	792	797	PF00069	0.614
MOD_NEK2_1	812	817	PF00069	0.555
MOD_NEK2_1	85	90	PF00069	0.497
MOD_NEK2_1	862	867	PF00069	0.722
MOD_NEK2_1	930	935	PF00069	0.721
MOD_NEK2_1	970	975	PF00069	0.587
MOD_PIKK_1	211	217	PF00454	0.798
MOD_PIKK_1	470	476	PF00454	0.686
MOD_PK_1	149	155	PF00069	0.734
MOD_PKA_2	339	345	PF00069	0.673
MOD_PKA_2	364	370	PF00069	0.723
MOD_PKA_2	439	445	PF00069	0.784
MOD_PKA_2	52	58	PF00069	0.727
MOD_PKA_2	668	674	PF00069	0.735
MOD_PKA_2	935	941	PF00069	0.550
MOD_PKA_2	971	977	PF00069	0.582
MOD_PKB_1	147	155	PF00069	0.732
MOD_Plk_1	313	319	PF00069	0.636
MOD_Plk_1	37	43	PF00069	0.460
MOD_Plk_1	554	560	PF00069	0.761
MOD_Plk_1	626	632	PF00069	0.809
MOD_Plk_1	66	72	PF00069	0.765
MOD_Plk_1	708	714	PF00069	0.649
MOD_Plk_1	925	931	PF00069	0.607
MOD_Plk_1	957	963	PF00069	0.691
MOD_Plk_1	975	981	PF00069	0.625
MOD_Plk_4	163	169	PF00069	0.751
MOD_Plk_4	26	32	PF00069	0.587
MOD_Plk_4	444	450	PF00069	0.837
MOD_Plk_4	495	501	PF00069	0.646
MOD_Plk_4	578	584	PF00069	0.651
MOD_Plk_4	788	794	PF00069	0.643
MOD_Plk_4	89	95	PF00069	0.653
MOD_Plk_4	97	103	PF00069	0.650
MOD_Plk_4	975	981	PF00069	0.634
MOD_ProDKin_1	120	126	PF00069	0.776
MOD_ProDKin_1	186	192	PF00069	0.707
MOD_ProDKin_1	261	267	PF00069	0.852
MOD_ProDKin_1	373	379	PF00069	0.812
MOD_ProDKin_1	434	440	PF00069	0.838
MOD_ProDKin_1	492	498	PF00069	0.678
MOD_ProDKin_1	564	570	PF00069	0.755
MOD_ProDKin_1	586	592	PF00069	0.809
MOD_ProDKin_1	632	638	PF00069	0.704
MOD_ProDKin_1	70	76	PF00069	0.605
MOD_ProDKin_1	786	792	PF00069	0.816
MOD_ProDKin_1	807	813	PF00069	0.668
MOD_ProDKin_1	830	836	PF00069	0.733
MOD_ProDKin_1	947	953	PF00069	0.770
TRG_DiLeu_BaEn_1	444	449	PF01217	0.776
TRG_DiLeu_BaEn_1	749	754	PF01217	0.722
TRG_DiLeu_BaEn_1	926	931	PF01217	0.730
TRG_DiLeu_BaLyEn_6	414	419	PF01217	0.735
TRG_DiLeu_LyEn_5	740	745	PF01217	0.729
TRG_ENDOCYTIC_2	312	315	PF00928	0.801
TRG_ENDOCYTIC_2	488	491	PF00928	0.738
TRG_ENDOCYTIC_2	526	529	PF00928	0.791
TRG_ENDOCYTIC_2	733	736	PF00928	0.800
TRG_ENDOCYTIC_2	800	803	PF00928	0.766
TRG_ENDOCYTIC_2	916	919	PF00928	0.535
TRG_ER_diArg_1	431	433	PF00400	0.777
TRG_ER_diArg_1	514	517	PF00400	0.773
TRG_ER_diArg_1	725	728	PF00400	0.700
TRG_ER_diArg_1	767	769	PF00400	0.695
TRG_ER_diArg_1	913	915	PF00400	0.683
TRG_Pf-PMV_PEXEL_1	417	421	PF00026	0.730
TRG_Pf-PMV_PEXEL_1	611	616	PF00026	0.809
TRG_Pf-PMV_PEXEL_1	727	731	PF00026	0.571
TRG_Pf-PMV_PEXEL_1	768	772	PF00026	0.695

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IDY5	Leishmania donovani	87%	100%
A4HF29	Leishmania braziliensis	64%	100%
A4I2B7	Leishmania infantum	87%	100%
E9AYG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%