LeishMANIAdb
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DUF4457 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF4457 domain-containing protein
Gene product:
Domain of unknown function (DUF4457), putative
Species:
Leishmania major
UniProt:
Q4Q8Z9_LEIMA
TriTrypDb:
LmjF.26.1930 * , LMJLV39_260025700 * , LMJSD75_260024200 *
Length:
1809

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q8Z9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1037 1041 PF00656 0.596
CLV_C14_Caspase3-7 150 154 PF00656 0.611
CLV_C14_Caspase3-7 1556 1560 PF00656 0.460
CLV_C14_Caspase3-7 1609 1613 PF00656 0.581
CLV_C14_Caspase3-7 1615 1619 PF00656 0.497
CLV_C14_Caspase3-7 315 319 PF00656 0.479
CLV_C14_Caspase3-7 354 358 PF00656 0.585
CLV_C14_Caspase3-7 424 428 PF00656 0.474
CLV_C14_Caspase3-7 643 647 PF00656 0.530
CLV_C14_Caspase3-7 903 907 PF00656 0.606
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IH58 Leishmania donovani 86% 100%
A4I2C1 Leishmania infantum 86% 100%
E9AYH3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS