LeishMANIAdb
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Putative 60S ribosomal protein L35

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative 60S ribosomal protein L35
Gene product:
60S ribosomal protein L35, putative
Species:
Leishmania major
UniProt:
Q4Q8V7_LEIMA
TriTrypDb:
LmjF.26.2330 , LMJLV39_260030100 , LMJSD75_260028400
Length:
127

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. yes yes: 7
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
TermNameLevelCount
GO:0005730 nucleolus 5 2
GO:0005737 cytoplasm 2 2
GO:0015934 large ribosomal subunit 4 10
GO:0022625 cytosolic large ribosomal subunit 5 10
GO:0032991 protein-containing complex 1 10
GO:0043226 organelle 2 2
GO:0043228 non-membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043232 intracellular non-membrane-bounded organelle 4 2
GO:0044391 ribosomal subunit 3 10
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Expansion

Sequence features

Q4Q8V7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8V7

Function

Biological processes
TermNameLevelCount
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 10 10
GO:0000470 maturation of LSU-rRNA 9 10
GO:0006139 nucleobase-containing compound metabolic process 3 10
GO:0006364 rRNA processing 8 10
GO:0006396 RNA processing 6 10
GO:0006412 translation 4 10
GO:0006518 peptide metabolic process 4 10
GO:0006725 cellular aromatic compound metabolic process 3 10
GO:0006807 nitrogen compound metabolic process 2 10
GO:0008152 metabolic process 1 10
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Molecular functions
TermNameLevelCount
GO:0003676 nucleic acid binding 3 2
GO:0003723 RNA binding 4 2
GO:0003729 mRNA binding 5 2
GO:0003735 structural constituent of ribosome 2 10
GO:0005198 structural molecule activity 1 10
GO:0005488 binding 1 2
GO:0097159 organic cyclic compound binding 2 2
GO:1901363 heterocyclic compound binding 2 2
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 105 107 PF00675 0.504
CLV_NRD_NRD_1 51 53 PF00675 0.289
CLV_NRD_NRD_1 76 78 PF00675 0.502
CLV_NRD_NRD_1 95 97 PF00675 0.423
CLV_PCSK_KEX2_1 120 122 PF00082 0.508
CLV_PCSK_KEX2_1 94 96 PF00082 0.493
CLV_PCSK_PC1ET2_1 120 122 PF00082 0.598
CLV_PCSK_SKI1_1 20 24 PF00082 0.356
CLV_PCSK_SKI1_1 57 61 PF00082 0.301
CLV_PCSK_SKI1_1 96 100 PF00082 0.548
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0S4J165 Bodo saltans 71% 100%
A0A1D8PK30 Candida albicans (strain SC5314 / ATCC MYA-2876) 40% 100%
A0A1X0P858 Trypanosomatidae 76% 100%
A0A3Q8IDZ4 Leishmania donovani 98% 100%
A0A3R7N3R9 Trypanosoma rangeli 74% 100%
A4HF78 Leishmania braziliensis 87% 100%
A4I2G1 Leishmania infantum 99% 100%
C9ZX35 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 72% 100%
E9AYL4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
O74904 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 39% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS