NADH-u_ox-rdase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit, putative

Species:

Leishmania major

UniProt:

Q4Q8P5_LEIMA

TriTrypDb:

LmjF.28.0250 , LMJLV39_280007800 , LMJSD75_280007700

Length:

297

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q8P5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8P5

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	169	171	PF00675	0.473
CLV_NRD_NRD_1	182	184	PF00675	0.349
CLV_NRD_NRD_1	200	202	PF00675	0.417
CLV_NRD_NRD_1	238	240	PF00675	0.538
CLV_NRD_NRD_1	58	60	PF00675	0.501
CLV_PCSK_KEX2_1	184	186	PF00082	0.482
CLV_PCSK_KEX2_1	195	197	PF00082	0.447
CLV_PCSK_KEX2_1	200	202	PF00082	0.438
CLV_PCSK_KEX2_1	58	60	PF00082	0.501
CLV_PCSK_PC1ET2_1	184	186	PF00082	0.496

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILT8	Leptomonas seymouri	69%	99%
A0A0S4IUG6	Bodo saltans	51%	100%
A0A1X0NVZ8	Trypanosomatidae	64%	100%
A0A3S7X178	Leishmania donovani	99%	100%
A4HG66	Leishmania braziliensis	92%	100%
A4I3A9	Leishmania infantum	98%	100%
D0A7S5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	100%
E9AZI6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
V5DAH1	Trypanosoma cruzi	64%	100%

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