Non-specific serine/threonine protein kinase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q8P4_LEIMA

TriTrypDb:

LmjF.28.0260 , LMJLV39_280007900 , LMJSD75_280007800

Length:

1062

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q8P4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8P4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	119	123	PF00656	0.771
CLV_C14_Caspase3-7	161	165	PF00656	0.535
CLV_NRD_NRD_1	471	473	PF00675	0.676
CLV_NRD_NRD_1	475	477	PF00675	0.615
CLV_NRD_NRD_1	651	653	PF00675	0.691
CLV_NRD_NRD_1	791	793	PF00675	0.552
CLV_NRD_NRD_1	797	799	PF00675	0.521
CLV_NRD_NRD_1	815	817	PF00675	0.511
CLV_NRD_NRD_1	870	872	PF00675	0.664
CLV_NRD_NRD_1	924	926	PF00675	0.603

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I917	Leptomonas seymouri	38%	86%
A0A1X0NVC0	Trypanosomatidae	22%	96%
A0A3Q8IGK9	Leishmania donovani	92%	99%
A0A422N0G7	Trypanosoma rangeli	24%	100%
A4HG67	Leishmania braziliensis	78%	100%
E9AZI7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
V5BEI0	Trypanosoma cruzi	24%	100%

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