40S ribosomal protein S26

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein S26, putative

Species:

Leishmania major

UniProt:

Q4Q8L6_LEIMA

TriTrypDb:

LmjF.28.0540 , LMJLV39_280010900 , LMJSD75_280010900

Length:

112

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0015935	small ribosomal subunit	4	3
GO:0022627	cytosolic small ribosomal subunit	5	3
GO:0032991	protein-containing complex	1	15
GO:0044391	ribosomal subunit	3	3
GO:1990904	ribonucleoprotein complex	2	15
GO:0005840	ribosome	5	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

Q4Q8L6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8L6

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	15
GO:0006518	peptide metabolic process	4	15
GO:0006807	nitrogen compound metabolic process	2	15
GO:0008152	metabolic process	1	15
GO:0009058	biosynthetic process	2	15
GO:0009059	macromolecule biosynthetic process	4	15
GO:0009987	cellular process	1	15
GO:0019538	protein metabolic process	3	15
GO:0034641	cellular nitrogen compound metabolic process	3	15
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	15
GO:0043043	peptide biosynthetic process	5	15
GO:0043170	macromolecule metabolic process	3	15
GO:0043603	amide metabolic process	3	15
GO:0043604	amide biosynthetic process	4	15
GO:0044237	cellular metabolic process	2	15
GO:0044238	primary metabolic process	2	15
GO:0044249	cellular biosynthetic process	3	15
GO:0044260	obsolete cellular macromolecule metabolic process	3	15
GO:0044271	cellular nitrogen compound biosynthetic process	4	15
GO:0071704	organic substance metabolic process	2	15
GO:1901564	organonitrogen compound metabolic process	3	15
GO:1901566	organonitrogen compound biosynthetic process	4	15
GO:1901576	organic substance biosynthetic process	3	15

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	3
GO:0003723	RNA binding	4	3
GO:0003729	mRNA binding	5	3
GO:0003735	structural constituent of ribosome	2	15
GO:0005198	structural molecule activity	1	15
GO:0005488	binding	1	3
GO:0097159	organic cyclic compound binding	2	3
GO:1901363	heterocyclic compound binding	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	44	46	PF00675	0.214
CLV_NRD_NRD_1	5	7	PF00675	0.218
CLV_NRD_NRD_1	95	97	PF00675	0.214
CLV_PCSK_KEX2_1	4	6	PF00082	0.217
CLV_PCSK_KEX2_1	44	46	PF00082	0.214
CLV_PCSK_PC1ET2_1	4	6	PF00082	0.196
CLV_PCSK_PC7_1	40	46	PF00082	0.214
CLV_PCSK_SKI1_1	44	48	PF00082	0.210
DOC_MAPK_gen_1	96	106	PF00069	0.408
DOC_PP4_FxxP_1	66	69	PF00568	0.396
DOC_SPAK_OSR1_1	40	44	PF12202	0.396
DOC_SPAK_OSR1_1	76	80	PF12202	0.478
DOC_USP7_MATH_1	13	17	PF00917	0.423
DOC_USP7_MATH_1	82	86	PF00917	0.414
DOC_WW_Pin1_4	29	34	PF00397	0.487
DOC_WW_Pin1_4	56	61	PF00397	0.478
LIG_EH1_1	40	48	PF00400	0.396
LIG_FHA_1	99	105	PF00498	0.404
LIG_FHA_2	30	36	PF00498	0.508
LIG_PCNA_APIM_2	38	44	PF02747	0.396
LIG_SH2_STAP1	100	104	PF00017	0.478
LIG_SH2_STAT3	72	75	PF00017	0.408
LIG_SH2_STAT5	100	103	PF00017	0.478
LIG_SH3_1	102	108	PF00018	0.618
LIG_SH3_3	102	108	PF00018	0.593
MOD_CDK_SPK_2	29	34	PF00069	0.507
MOD_CDK_SPxxK_3	29	36	PF00069	0.507
MOD_Cter_Amidation	109	112	PF01082	0.604
MOD_GlcNHglycan	50	53	PF01048	0.196
MOD_PKA_2	98	104	PF00069	0.420
MOD_ProDKin_1	29	35	PF00069	0.487
MOD_ProDKin_1	56	62	PF00069	0.478
TRG_ER_diArg_1	17	20	PF00400	0.460
TRG_ER_diArg_1	43	45	PF00400	0.412
TRG_ER_diArg_1	88	91	PF00400	0.396

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4J7E9	Bodo saltans	77%	100%
A0A0S4JLP0	Bodo saltans	78%	85%
A0A1X0NYJ2	Trypanosomatidae	82%	100%
A0A1X0P1D3	Trypanosomatidae	79%	100%
A0A3R7M973	Trypanosoma rangeli	77%	100%
A0A3R7NTW6	Trypanosoma rangeli	82%	100%
A0A3S5H7I8	Leishmania donovani	98%	100%
A4HG94	Leishmania braziliensis	94%	100%
A4I3C8	Leishmania infantum	98%	100%
D0A817	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	82%	100%
E9AZL5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
O45499	Caenorhabditis elegans	54%	96%
O93931	Schizophyllum commune	47%	89%
P13008	Drosophila melanogaster	50%	98%
P21772	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	48%	94%
P27085	Octopus vulgaris	50%	88%
P30742	Cricetus cricetus	50%	97%
P39938	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	45%	94%
P39939	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	45%	94%
P41959	Brugia pahangi	53%	100%
P49171	Sus scrofa	52%	97%
P49206	Arabidopsis thaliana	53%	85%
P49216	Oryza sativa subsp. japonica	50%	84%
P61251	Macaca fascicularis	52%	97%
P62854	Homo sapiens	52%	97%
P62855	Mus musculus	52%	97%
P62856	Rattus norvegicus	52%	97%
Q4Q6X0	Leishmania major	98%	100%
Q54TL8	Dictyostelium discoideum	49%	100%
Q56JV1	Bos taurus	52%	97%
Q5ALV6	Candida albicans (strain SC5314 / ATCC MYA-2876)	50%	94%
Q5JNZ5	Homo sapiens	48%	97%
Q6Q312	Ovis aries	50%	97%
Q8LPJ7	Arabidopsis thaliana	53%	84%
Q8SRN2	Encephalitozoon cuniculi (strain GB-M1)	45%	100%
Q9BHU1	Sterkiella nova	46%	90%
Q9GT45	Anopheles gambiae	50%	97%
Q9LYK9	Arabidopsis thaliana	54%	86%
Q9UT56	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	93%
Q9UTG4	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	52%	94%
V5BQE2	Trypanosoma cruzi	83%	100%