LeishMANIAdb
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Leishmanolysin

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Leishmanolysin
Gene product:
major surface protease gp63, putative
Species:
Leishmania major
UniProt:
Q4Q8L3_LEIMA
TriTrypDb:
LmjF.28.0570 , LMJLV39_280011300 * , LMJSD75_280011300 *
Length:
566

Annotations

LeishMANIAdb annotations

Publication identifier(s): 31356625
GPI-anchored cell surface protease. Broad-spectrum ectoenzyme involved in pathogenesis. Heavily expanded family in all parazitic species.. Localization: Cell surface (experimental)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 4
Silverman et al. no yes: 0
Pissara et al. yes yes: 66
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 51, no: 14
NetGPI no yes: 0, no: 65
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 7
GO:0016020 membrane 2 66
GO:0110165 cellular anatomical entity 1 66
GO:0018995 host cellular component 2 4
GO:0033643 host cell part 3 4
GO:0033646 host intracellular part 4 4
GO:0033647 host intracellular organelle 5 4
GO:0033648 host intracellular membrane-bounded organelle 6 4
GO:0042025 host cell nucleus 7 4

Expansion

Sequence features

Q4Q8L3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8L3

Function

Biological processes
Term Name Level Count
GO:0006508 proteolysis 4 66
GO:0006807 nitrogen compound metabolic process 2 66
GO:0007155 cell adhesion 2 66
GO:0008152 metabolic process 1 66
GO:0009987 cellular process 1 66
GO:0019538 protein metabolic process 3 66
GO:0043170 macromolecule metabolic process 3 66
GO:0044238 primary metabolic process 2 66
GO:0071704 organic substance metabolic process 2 66
GO:1901564 organonitrogen compound metabolic process 3 66
GO:0009966 regulation of signal transduction 4 4
GO:0010646 regulation of cell communication 4 4
GO:0010749 regulation of nitric oxide mediated signal transduction 6 4
GO:0023051 regulation of signaling 3 4
GO:0035821 modulation of process of another organism 2 4
GO:0044003 modulation by symbiont of host process 3 4
GO:0044068 modulation by symbiont of host cellular process 4 4
GO:0044081 modulation by symbiont of host nitric oxide-mediated signal transduction 5 4
GO:0044403 biological process involved in symbiotic interaction 2 4
GO:0044419 biological process involved in interspecies interaction between organisms 1 4
GO:0044501 modulation of signal transduction in another organism 3 4
GO:0048583 regulation of response to stimulus 3 4
GO:0050789 regulation of biological process 2 4
GO:0050794 regulation of cellular process 3 4
GO:0051701 biological process involved in interaction with host 3 4
GO:0052027 modulation by symbiont of host signal transduction pathway 4 4
GO:0065007 biological regulation 1 4
GO:0075130 modulation by symbiont of host protein kinase-mediated signal transduction 5 4
GO:1902531 regulation of intracellular signal transduction 5 4
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 66
GO:0004175 endopeptidase activity 4 66
GO:0004222 metalloendopeptidase activity 5 66
GO:0005488 binding 1 66
GO:0008233 peptidase activity 3 66
GO:0008237 metallopeptidase activity 4 66
GO:0016787 hydrolase activity 2 66
GO:0043167 ion binding 2 66
GO:0043169 cation binding 3 66
GO:0046872 metal ion binding 4 66
GO:0140096 catalytic activity, acting on a protein 2 66
GO:0008047 enzyme activator activity 3 4
GO:0008160 protein tyrosine phosphatase activator activity 6 4
GO:0019208 phosphatase regulator activity 3 4
GO:0019211 phosphatase activator activity 4 4
GO:0019888 protein phosphatase regulator activity 4 4
GO:0030234 enzyme regulator activity 2 4
GO:0072542 protein phosphatase activator activity 5 4
GO:0098772 molecular function regulator activity 1 4
GO:0140677 molecular function activator activity 2 4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 29 33 PF00656 0.430
CLV_C14_Caspase3-7 374 378 PF00656 0.388
CLV_MEL_PAP_1 48 54 PF00089 0.584
CLV_NRD_NRD_1 304 306 PF00675 0.432
CLV_PCSK_KEX2_1 122 124 PF00082 0.558
CLV_PCSK_KEX2_1 303 305 PF00082 0.431
CLV_PCSK_PC1ET2_1 122 124 PF00082 0.561
CLV_PCSK_PC1ET2_1 303 305 PF00082 0.457
CLV_PCSK_SKI1_1 122 126 PF00082 0.525
CLV_PCSK_SKI1_1 243 247 PF00082 0.490
CLV_PCSK_SKI1_1 249 253 PF00082 0.438
CLV_PCSK_SKI1_1 3 7 PF00082 0.574
CLV_PCSK_SKI1_1 305 309 PF00082 0.471
CLV_PCSK_SKI1_1 391 395 PF00082 0.502
DEG_APCC_DBOX_1 122 130 PF00400 0.219
DEG_Nend_UBRbox_4 1 3 PF02207 0.427
DOC_CKS1_1 453 458 PF01111 0.211
DOC_CYCLIN_RxL_1 119 127 PF00134 0.207
DOC_MAPK_gen_1 119 128 PF00069 0.318
DOC_MAPK_HePTP_8 116 128 PF00069 0.207
DOC_MAPK_MEF2A_6 119 128 PF00069 0.327
DOC_MAPK_MEF2A_6 3 12 PF00069 0.539
DOC_MAPK_MEF2A_6 467 475 PF00069 0.265
DOC_MAPK_MEF2A_6 553 562 PF00069 0.197
DOC_MAPK_NFAT4_5 123 131 PF00069 0.208
DOC_PP2B_LxvP_1 128 131 PF13499 0.210
DOC_PP4_FxxP_1 408 411 PF00568 0.274
DOC_USP7_MATH_1 253 257 PF00917 0.199
DOC_USP7_UBL2_3 173 177 PF12436 0.197
DOC_USP7_UBL2_3 270 274 PF12436 0.219
DOC_USP7_UBL2_3 481 485 PF12436 0.203
DOC_WW_Pin1_4 214 219 PF00397 0.222
DOC_WW_Pin1_4 260 265 PF00397 0.275
DOC_WW_Pin1_4 452 457 PF00397 0.248
DOC_WW_Pin1_4 504 509 PF00397 0.299
LIG_14-3-3_CanoR_1 108 117 PF00244 0.410
LIG_14-3-3_CanoR_1 391 401 PF00244 0.386
LIG_APCC_ABBA_1 134 139 PF00400 0.309
LIG_APCC_ABBA_1 80 85 PF00400 0.224
LIG_APCC_ABBAyCdc20_2 79 85 PF00400 0.224
LIG_BRCT_BRCA1_1 506 510 PF00533 0.417
LIG_BRCT_BRCA1_2 506 512 PF00533 0.227
LIG_FHA_1 225 231 PF00498 0.398
LIG_FHA_1 290 296 PF00498 0.196
LIG_FHA_1 363 369 PF00498 0.308
LIG_FHA_1 436 442 PF00498 0.341
LIG_FHA_1 498 504 PF00498 0.392
LIG_FHA_1 60 66 PF00498 0.602
LIG_FHA_1 70 76 PF00498 0.428
LIG_FHA_1 82 88 PF00498 0.337
LIG_GBD_Chelix_1 555 563 PF00786 0.308
LIG_Integrin_isoDGR_2 206 208 PF01839 0.469
LIG_LIR_Gen_1 283 291 PF02991 0.375
LIG_LIR_Gen_1 403 413 PF02991 0.398
LIG_LIR_Gen_1 519 528 PF02991 0.312
LIG_LIR_LC3C_4 62 67 PF02991 0.376
LIG_LIR_Nem_3 178 184 PF02991 0.333
LIG_LIR_Nem_3 283 289 PF02991 0.376
LIG_LIR_Nem_3 403 408 PF02991 0.362
LIG_LIR_Nem_3 421 425 PF02991 0.261
LIG_LIR_Nem_3 519 523 PF02991 0.312
LIG_LIR_Nem_3 531 536 PF02991 0.389
LIG_MAD2 123 131 PF02301 0.323
LIG_NRBOX 124 130 PF00104 0.210
LIG_PDZ_Class_2 561 566 PF00595 0.480
LIG_SH2_CRK 321 325 PF00017 0.310
LIG_SH2_NCK_1 339 343 PF00017 0.331
LIG_SH2_STAT5 220 223 PF00017 0.359
LIG_SH2_STAT5 404 407 PF00017 0.319
LIG_SH2_STAT5 483 486 PF00017 0.274
LIG_SH2_STAT5 514 517 PF00017 0.356
LIG_SH3_3 15 21 PF00018 0.703
LIG_SH3_3 373 379 PF00018 0.213
LIG_SH3_3 450 456 PF00018 0.385
LIG_SH3_3 55 61 PF00018 0.426
LIG_SUMO_SIM_par_1 424 430 PF11976 0.304
LIG_Vh1_VBS_1 548 566 PF01044 0.209
LIG_WRC_WIRS_1 254 259 PF05994 0.409
MOD_CDK_SPK_2 214 219 PF00069 0.210
MOD_CK1_1 107 113 PF00069 0.223
MOD_CK1_1 256 262 PF00069 0.239
MOD_CK1_1 322 328 PF00069 0.330
MOD_CK1_1 381 387 PF00069 0.371
MOD_CK1_1 396 402 PF00069 0.411
MOD_CK1_1 504 510 PF00069 0.360
MOD_CK1_1 519 525 PF00069 0.364
MOD_CK1_1 53 59 PF00069 0.581
MOD_CK1_1 88 94 PF00069 0.211
MOD_CK1_1 97 103 PF00069 0.214
MOD_CK2_1 109 115 PF00069 0.243
MOD_CK2_1 163 169 PF00069 0.293
MOD_CK2_1 528 534 PF00069 0.377
MOD_CK2_1 53 59 PF00069 0.601
MOD_GlcNHglycan 111 114 PF01048 0.510
MOD_GlcNHglycan 131 134 PF01048 0.531
MOD_GlcNHglycan 185 188 PF01048 0.453
MOD_GlcNHglycan 190 193 PF01048 0.467
MOD_GlcNHglycan 315 318 PF01048 0.513
MOD_GlcNHglycan 321 324 PF01048 0.554
MOD_GlcNHglycan 462 466 PF01048 0.410
MOD_GlcNHglycan 489 492 PF01048 0.609
MOD_GlcNHglycan 52 55 PF01048 0.768
MOD_GlcNHglycan 534 539 PF01048 0.549
MOD_GlcNHglycan 96 99 PF01048 0.535
MOD_GSK3_1 183 190 PF00069 0.307
MOD_GSK3_1 256 263 PF00069 0.211
MOD_GSK3_1 359 366 PF00069 0.285
MOD_GSK3_1 392 399 PF00069 0.377
MOD_GSK3_1 457 464 PF00069 0.401
MOD_GSK3_1 497 504 PF00069 0.313
MOD_GSK3_1 534 541 PF00069 0.367
MOD_GSK3_1 81 88 PF00069 0.335
MOD_N-GLC_1 214 219 PF02516 0.397
MOD_N-GLC_1 362 367 PF02516 0.532
MOD_N-GLC_1 501 506 PF02516 0.426
MOD_N-GLC_1 528 533 PF02516 0.571
MOD_N-GLC_1 88 93 PF02516 0.489
MOD_NEK2_1 1 6 PF00069 0.522
MOD_NEK2_1 104 109 PF00069 0.335
MOD_NEK2_1 183 188 PF00069 0.273
MOD_NEK2_1 239 244 PF00069 0.349
MOD_NEK2_1 329 334 PF00069 0.257
MOD_NEK2_1 441 446 PF00069 0.257
MOD_NEK2_1 461 466 PF00069 0.261
MOD_NEK2_2 163 168 PF00069 0.241
MOD_NEK2_2 253 258 PF00069 0.201
MOD_PIKK_1 280 286 PF00454 0.220
MOD_PIKK_1 363 369 PF00454 0.327
MOD_PIKK_1 88 94 PF00454 0.210
MOD_PKA_2 104 110 PF00069 0.390
MOD_PKA_2 207 213 PF00069 0.412
MOD_PKA_2 50 56 PF00069 0.536
MOD_Plk_1 152 158 PF00069 0.289
MOD_Plk_1 461 467 PF00069 0.207
MOD_Plk_1 501 507 PF00069 0.295
MOD_Plk_1 528 534 PF00069 0.312
MOD_Plk_1 541 547 PF00069 0.520
MOD_Plk_4 190 196 PF00069 0.346
MOD_Plk_4 400 406 PF00069 0.390
MOD_Plk_4 441 447 PF00069 0.262
MOD_Plk_4 528 534 PF00069 0.356
MOD_ProDKin_1 214 220 PF00069 0.222
MOD_ProDKin_1 260 266 PF00069 0.275
MOD_ProDKin_1 452 458 PF00069 0.248
MOD_ProDKin_1 504 510 PF00069 0.299
MOD_SUMO_for_1 307 310 PF00179 0.271
MOD_SUMO_for_1 340 343 PF00179 0.207
TRG_DiLeu_BaEn_3 534 540 PF01217 0.257
TRG_ENDOCYTIC_2 321 324 PF00928 0.301
TRG_ENDOCYTIC_2 446 449 PF00928 0.210
TRG_ENDOCYTIC_2 520 523 PF00928 0.333
TRG_ENDOCYTIC_2 536 539 PF00928 0.390
TRG_NLS_MonoExtN_4 119 125 PF00514 0.265
TRG_Pf-PMV_PEXEL_1 123 127 PF00026 0.468

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IL11 Leptomonas seymouri 40% 86%
A0A0S4IS53 Bodo saltans 38% 100%
A0A0S4IUT6 Bodo saltans 30% 69%
A0A0S4IUU1 Bodo saltans 31% 86%
A0A0S4IYM3 Bodo saltans 32% 78%
A0A1X0NDG7 Trypanosomatidae 31% 87%
A0A1X0NDJ3 Trypanosomatidae 29% 78%
A0A1X0NDK2 Trypanosomatidae 31% 98%
A0A1X0NDK7 Trypanosomatidae 29% 79%
A0A1X0NDK9 Trypanosomatidae 28% 100%
A0A1X0NDM7 Trypanosomatidae 30% 88%
A0A1X0NDU8 Trypanosomatidae 28% 85%
A0A1X0NE71 Trypanosomatidae 29% 100%
A0A1X0NER9 Trypanosomatidae 34% 88%
A0A1X0NET7 Trypanosomatidae 32% 100%
A0A1X0NEX7 Trypanosomatidae 33% 86%
A0A1X0NEZ6 Trypanosomatidae 30% 87%
A0A1X0NF32 Trypanosomatidae 29% 100%
A0A1X0NF41 Trypanosomatidae 30% 92%
A0A1X0NFJ0 Trypanosomatidae 31% 100%
A0A1X0NFK3 Trypanosomatidae 28% 84%
A0A1X0NFU4 Trypanosomatidae 28% 69%
A0A1X0NFZ9 Trypanosomatidae 31% 100%
A0A1X0NG20 Trypanosomatidae 32% 91%
A0A1X0NGN3 Trypanosomatidae 37% 100%
A0A1X0NGP3 Trypanosomatidae 30% 66%
A0A1X0NGY3 Trypanosomatidae 28% 74%
A0A1X0NGZ3 Trypanosomatidae 30% 94%
A0A1X0NHP6 Trypanosomatidae 30% 100%
A0A1X0NHQ6 Trypanosomatidae 31% 100%
A0A1X0NI74 Trypanosomatidae 28% 76%
A0A1X0NII4 Trypanosomatidae 28% 67%
A0A1X0NIZ3 Trypanosomatidae 32% 100%
A0A1X0NJS3 Trypanosomatidae 31% 87%
A0A1X0NK66 Trypanosomatidae 31% 86%
A0A1X0NKJ8 Trypanosomatidae 29% 76%
A0A1X0NKW9 Trypanosomatidae 32% 100%
A0A1X0NME2 Trypanosomatidae 31% 90%
A0A1X0NMK3 Trypanosomatidae 28% 100%
A0A1X0NMK7 Trypanosomatidae 36% 100%
A0A1X0NMV0 Trypanosomatidae 29% 77%
A0A1X0NN43 Trypanosomatidae 31% 79%
A0A1X0NNK8 Trypanosomatidae 31% 86%
A0A1X0NPW0 Trypanosomatidae 30% 88%
A0A1X0NQJ5 Trypanosomatidae 32% 100%
A0A1X0NQM4 Trypanosomatidae 32% 100%
A0A1X0NQN3 Trypanosomatidae 35% 100%
A0A1X0NQU4 Trypanosomatidae 34% 88%
A0A1X0NQW6 Trypanosomatidae 30% 99%
A0A1X0NRF3 Trypanosomatidae 32% 84%
A0A1X0NRY8 Trypanosomatidae 34% 100%
A0A1X0NU16 Trypanosomatidae 37% 94%
A0A1X0NUR2 Trypanosomatidae 32% 77%
A0A1X0NV28 Trypanosomatidae 37% 96%
A0A1X0NVC3 Trypanosomatidae 30% 83%
A0A1X0NVE0 Trypanosomatidae 30% 72%
A0A1X0NW07 Trypanosomatidae 28% 90%
A0A1X0NX94 Trypanosomatidae 30% 87%
A0A1X0NX98 Trypanosomatidae 28% 71%
A0A1X0NXB6 Trypanosomatidae 30% 80%
A0A1X0NXH6 Trypanosomatidae 33% 77%
A0A1X0NXQ4 Trypanosomatidae 31% 83%
A0A1X0NXR7 Trypanosomatidae 34% 75%
A0A1X0NYE3 Trypanosomatidae 30% 91%
A0A1X0NYE7 Trypanosomatidae 31% 100%
A0A1X0NYN2 Trypanosomatidae 35% 100%
A0A1X0NYN4 Trypanosomatidae 29% 79%
A0A1X0NYS5 Trypanosomatidae 36% 94%
A0A1X0NYZ2 Trypanosomatidae 37% 100%
A0A1X0NZ46 Trypanosomatidae 32% 97%
A0A1X0NZ63 Trypanosomatidae 29% 89%
A0A1X0NZN6 Trypanosomatidae 30% 87%
A0A1X0P055 Trypanosomatidae 35% 96%
A0A1X0P0C4 Trypanosomatidae 30% 100%
A0A1X0P154 Trypanosomatidae 31% 94%
A0A1X0P331 Trypanosomatidae 37% 99%
A0A1X0P3K0 Trypanosomatidae 27% 78%
A0A1X0P3S2 Trypanosomatidae 29% 100%
A0A1X0P4L8 Trypanosomatidae 29% 100%
A0A1X0P4Y5 Trypanosomatidae 27% 88%
A0A1X0P544 Trypanosomatidae 28% 88%
A0A1X0P5J0 Trypanosomatidae 33% 83%
A0A1X0P7R3 Trypanosomatidae 39% 100%
A0A1X0P8B4 Trypanosomatidae 30% 100%
A0A1X0P9Z4 Trypanosomatidae 33% 100%
A0A1X0PB04 Trypanosomatidae 32% 100%
A0A3Q8I8N3 Leishmania donovani 39% 95%
A0A3Q8I8P8 Leishmania donovani 39% 94%
A0A3Q8I8S6 Leishmania donovani 38% 88%
A0A3Q8I8S9 Leishmania donovani 39% 94%
A0A3Q8IAZ8 Leishmania donovani 39% 95%
A0A3Q8IC35 Leishmania donovani 39% 95%
A0A3Q8IC44 Leishmania donovani 38% 96%
A0A3Q8IH61 Leishmania donovani 39% 96%
A0A3Q8IIN4 Leishmania donovani 40% 89%
A0A3R7JT49 Trypanosoma rangeli 37% 67%
A0A3R7JTB6 Trypanosoma rangeli 34% 81%
A0A3R7JUS0 Trypanosoma rangeli 34% 100%
A0A3R7JV87 Trypanosoma rangeli 37% 100%
A0A3R7K7T9 Trypanosoma rangeli 36% 94%
A0A3R7K9S1 Trypanosoma rangeli 37% 100%
A0A3R7KLR6 Trypanosoma rangeli 32% 88%
A0A3R7KMY2 Trypanosoma rangeli 36% 85%
A0A3R7LFC4 Trypanosoma rangeli 38% 84%
A0A3R7LFZ4 Trypanosoma rangeli 38% 100%
A0A3R7LWG1 Trypanosoma rangeli 34% 100%
A0A3R7LX11 Trypanosoma rangeli 36% 100%
A0A3R7M1R8 Trypanosoma rangeli 36% 98%
A0A3R7M574 Trypanosoma rangeli 36% 88%
A0A3R7M5K4 Trypanosoma rangeli 38% 100%
A0A3R7M7N6 Trypanosoma rangeli 36% 82%
A0A3R7MTS2 Trypanosoma rangeli 41% 100%
A0A3R7MW36 Trypanosoma rangeli 38% 100%
A0A3R7MXF4 Trypanosoma rangeli 40% 92%
A0A3R7N1W7 Trypanosoma rangeli 36% 97%
A0A3R7N289 Trypanosoma rangeli 34% 78%
A0A3R7N7I3 Trypanosoma rangeli 42% 100%
A0A3R7NTI8 Trypanosoma rangeli 36% 99%
A0A3R7R2J4 Trypanosoma rangeli 37% 88%
A0A3R7R5R1 Trypanosoma rangeli 36% 94%
A0A3R7R818 Trypanosoma rangeli 34% 100%
A0A3S5H6G0 Leishmania donovani 39% 94%
A0A3S5IQY2 Trypanosoma rangeli 39% 100%
A0A3S7WR43 Leishmania donovani 39% 95%
A0A3S7WR46 Leishmania donovani 40% 94%
A0A3S7WR60 Leishmania donovani 39% 94%
A0A3S7X192 Leishmania donovani 84% 100%
A0A422MP17 Trypanosoma rangeli 37% 100%
A0A422MRQ6 Trypanosoma rangeli 36% 76%
A0A422MTA9 Trypanosoma rangeli 33% 78%
A0A422MU95 Trypanosoma rangeli 36% 99%
A0A422MUY8 Trypanosoma rangeli 39% 100%
A0A422MVF5 Trypanosoma rangeli 36% 100%
A0A422MVS3 Trypanosoma rangeli 36% 100%
A0A422MW99 Trypanosoma rangeli 34% 76%
A0A422MZ47 Trypanosoma rangeli 38% 100%
A0A422MZG4 Trypanosoma rangeli 38% 96%
A0A422N361 Trypanosoma rangeli 37% 100%
A0A422N7Q6 Trypanosoma rangeli 37% 87%
A0A422NDS2 Trypanosoma rangeli 34% 97%
A0A422NDT3 Trypanosoma rangeli 32% 99%
A0A422NP82 Trypanosoma rangeli 39% 99%
A4H626 Leishmania braziliensis 39% 98%
A4H627 Leishmania braziliensis 39% 97%
A4H629 Leishmania braziliensis 40% 100%
A4H630 Leishmania braziliensis 39% 91%
A4H631 Leishmania braziliensis 40% 98%
A4H632 Leishmania braziliensis 37% 100%
A4H633 Leishmania braziliensis 40% 100%
A4H634 Leishmania braziliensis 39% 92%
A4H635 Leishmania braziliensis 38% 91%
A4H636 Leishmania braziliensis 39% 100%
A4H637 Leishmania braziliensis 39% 91%
A4H638 Leishmania braziliensis 39% 96%
A4H639 Leishmania braziliensis 37% 93%
A4H640 Leishmania braziliensis 39% 91%
A4H6D3 Leishmania braziliensis 36% 97%
A4H6D5 Leishmania braziliensis 38% 80%
A4H6D7 Leishmania braziliensis 38% 97%
A4H6D8 Leishmania braziliensis 40% 97%
A4H6D9 Leishmania braziliensis 40% 97%
A4H6E0 Leishmania braziliensis 39% 80%
A4H6E1 Leishmania braziliensis 36% 97%
A4H6E2 Leishmania braziliensis 35% 98%
A4H6E3 Leishmania braziliensis 39% 99%
A4H6E4 Leishmania braziliensis 40% 100%
A4H6E5 Leishmania braziliensis 39% 100%
A4HJI2 Leishmania braziliensis 39% 87%
A4HUF6 Leishmania infantum 40% 95%
A4HUF8 Leishmania infantum 39% 94%
A4HUF9 Leishmania infantum 38% 88%
A4HUG0 Leishmania infantum 39% 74%
A4I6X5 Leishmania infantum 40% 89%
C9ZUT5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 39% 97%
D0A1R8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 96%
D0A7S8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 84%
D0A855 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 37% 92%
E9AHH5 Leishmania infantum 85% 100%
E9AN53 Leishmania mexicana (strain MHOM/GT/2001/U1103) 40% 86%
E9AN54 Leishmania mexicana (strain MHOM/GT/2001/U1103) 40% 94%
E9AN55 Leishmania mexicana (strain MHOM/GT/2001/U1103) 39% 88%
E9AN56 Leishmania mexicana (strain MHOM/GT/2001/U1103) 39% 88%
E9AN57 Leishmania mexicana (strain MHOM/GT/2001/U1103) 39% 94%
E9AZL8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 100%
E9B1Z9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 40% 89%
O62446 Caenorhabditis elegans 25% 85%
P08148 Leishmania major 40% 94%
P15706 Leishmania chagasi 39% 94%
P23223 Leishmania donovani 39% 96%
P43150 Leishmania mexicana 39% 88%
Q00689 Leishmania guyanensis 38% 91%
Q06031 Crithidia fasciculata 38% 87%
Q27673 Leishmania amazonensis 39% 95%
Q29AK2 Drosophila pseudoobscura pseudoobscura 24% 83%
Q4Q662 Leishmania major 42% 100%
Q4QHG9 Leishmania major 40% 94%
Q4QHH0 Leishmania major 39% 88%
Q4QHH1 Leishmania major 39% 94%
Q4QHH2 Leishmania major 40% 94%
Q61YG1 Caenorhabditis briggsae 24% 85%
Q6LA77 Leishmania infantum 39% 94%
Q8BMN4 Mus musculus 24% 83%
Q8MNZ1 Leishmania tropica 38% 86%
Q96KR4 Homo sapiens 22% 86%
Q9VH19 Drosophila melanogaster 22% 83%
V5A303 Trypanosoma cruzi 41% 100%
V5A359 Trypanosoma cruzi 40% 100%
V5A488 Trypanosoma cruzi 35% 70%
V5AII7 Trypanosoma cruzi 39% 100%
V5AMH8 Trypanosoma cruzi 37% 100%
V5AN34 Trypanosoma cruzi 39% 100%
V5APQ4 Trypanosoma cruzi 34% 71%
V5AX72 Trypanosoma cruzi 35% 77%
V5B5M0 Trypanosoma cruzi 36% 77%
V5B9W5 Trypanosoma cruzi 31% 84%
V5BAL3 Trypanosoma cruzi 39% 100%
V5BAN1 Trypanosoma cruzi 36% 72%
V5BD39 Trypanosoma cruzi 43% 100%
V5BLT3 Trypanosoma cruzi 33% 90%
V5CI97 Trypanosoma cruzi 31% 89%
V5D358 Trypanosoma cruzi 34% 67%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS