LeishMANIAdb
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H15 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
H15 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q8L0_LEIMA
TriTrypDb:
LmjF.28.0600 , LMJLV39_280011600 , LMJSD75_280011600
Length:
95

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q8L0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8L0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 18 20 PF00675 0.584
CLV_NRD_NRD_1 26 28 PF00675 0.602
CLV_NRD_NRD_1 89 91 PF00675 0.625
CLV_PCSK_KEX2_1 26 28 PF00082 0.715
CLV_PCSK_KEX2_1 91 93 PF00082 0.652
CLV_PCSK_PC1ET2_1 26 28 PF00082 0.715
CLV_PCSK_PC1ET2_1 91 93 PF00082 0.683
CLV_PCSK_SKI1_1 80 84 PF00082 0.614
DEG_APCC_DBOX_1 62 70 PF00400 0.609
DOC_USP7_MATH_1 2 6 PF00917 0.728
DOC_USP7_MATH_1 53 57 PF00917 0.593
DOC_USP7_UBL2_3 79 83 PF12436 0.611
DOC_USP7_UBL2_3 9 13 PF12436 0.600
DOC_WW_Pin1_4 34 39 PF00397 0.695
LIG_14-3-3_CanoR_1 11 18 PF00244 0.639
LIG_14-3-3_CanoR_1 19 23 PF00244 0.665
LIG_14-3-3_CanoR_1 27 32 PF00244 0.685
LIG_BIR_II_1 1 5 PF00653 0.662
LIG_SH2_STAT5 46 49 PF00017 0.540
LIG_SUMO_SIM_anti_2 64 72 PF11976 0.652
MOD_CDK_SPxxK_3 34 41 PF00069 0.683
MOD_CK1_1 29 35 PF00069 0.693
MOD_CK1_1 5 11 PF00069 0.678
MOD_CK1_1 64 70 PF00069 0.656
MOD_CK1_1 72 78 PF00069 0.686
MOD_CK2_1 18 24 PF00069 0.612
MOD_CK2_1 45 51 PF00069 0.556
MOD_Cter_Amidation 88 91 PF01082 0.634
MOD_GlcNHglycan 13 16 PF01048 0.617
MOD_GlcNHglycan 47 50 PF01048 0.552
MOD_GlcNHglycan 71 74 PF01048 0.711
MOD_GSK3_1 53 60 PF00069 0.551
MOD_GSK3_1 64 71 PF00069 0.583
MOD_GSK3_1 7 14 PF00069 0.611
MOD_NEK2_1 18 23 PF00069 0.634
MOD_NEK2_2 2 7 PF00069 0.728
MOD_PKA_1 26 32 PF00069 0.618
MOD_PKA_2 18 24 PF00069 0.665
MOD_PKA_2 26 32 PF00069 0.686
MOD_Plk_4 64 70 PF00069 0.592
MOD_ProDKin_1 34 40 PF00069 0.687
TRG_ER_diLys_1 91 95 PF00400 0.777
TRG_NLS_Bipartite_1 78 95 PF00514 0.666
TRG_NLS_MonoCore_2 89 94 PF00514 0.696
TRG_NLS_MonoExtN_4 88 95 PF00514 0.680

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P851 Leptomonas seymouri 79% 98%
A0A0S4J7E0 Bodo saltans 47% 90%
A0A1X0NYW9 Trypanosomatidae 67% 95%
A0A3Q8IDP4 Leishmania donovani 97% 100%
A4HGA0 Leishmania braziliensis 92% 100%
A4I3D4 Leishmania infantum 97% 100%
E9AZM1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
V5DH83 Trypanosoma cruzi 65% 94%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS