LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4Q8K3_LEIMA
TriTrypDb:
LmjF.28.0670 , LMJLV39_280012300 * , LMJSD75_280012300 *
Length:
360

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q8K3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8K3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 111 115 PF00656 0.664
CLV_C14_Caspase3-7 283 287 PF00656 0.450
CLV_NRD_NRD_1 207 209 PF00675 0.668
CLV_NRD_NRD_1 212 214 PF00675 0.654
CLV_PCSK_KEX2_1 142 144 PF00082 0.411
CLV_PCSK_KEX2_1 212 214 PF00082 0.578
CLV_PCSK_PC1ET2_1 142 144 PF00082 0.411
CLV_PCSK_PC7_1 208 214 PF00082 0.546
CLV_PCSK_SKI1_1 200 204 PF00082 0.631
CLV_PCSK_SKI1_1 256 260 PF00082 0.335
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IA55 Leptomonas seymouri 48% 75%
A0A3Q8IQE0 Leishmania donovani 89% 71%
A4HGA7 Leishmania braziliensis 74% 100%
A4I3E1 Leishmania infantum 89% 100%
E9AZM8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS