Putative RNA binding protein rbp16

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA binding protein rbp16, putative

Species:

Leishmania major

UniProt:

Q4Q8I6_LEIMA

TriTrypDb:

LmjF.28.0825 , LMJLV39_280014200 , LMJSD75_280014200

Length:

142

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0005737	cytoplasm	2	2
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q8I6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8I6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	11
GO:0005488	binding	1	11
GO:0097159	organic cyclic compound binding	2	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_Nbox_1	1	3	PF02207	0.578
DOC_MAPK_gen_1	40	47	PF00069	0.496
DOC_MAPK_MEF2A_6	9	16	PF00069	0.671
DOC_PP1_RVXF_1	19	26	PF00149	0.335
DOC_WW_Pin1_4	97	102	PF00397	0.578
LIG_14-3-3_CanoR_1	3	8	PF00244	0.606
LIG_AP2alpha_1	138	142	PF02296	0.654
LIG_BRCT_BRCA1_1	138	142	PF00533	0.631
LIG_FHA_1	17	23	PF00498	0.515
LIG_FHA_2	75	81	PF00498	0.482
LIG_LIR_Nem_3	54	60	PF02991	0.489
LIG_PDZ_Class_3	137	142	PF00595	0.612
LIG_Pex14_2	138	142	PF04695	0.654
LIG_SH2_CRK	57	61	PF00017	0.562
LIG_SH3_3	79	85	PF00018	0.496
LIG_SH3_3	88	94	PF00018	0.586
LIG_SUMO_SIM_anti_2	13	19	PF11976	0.629
MOD_CDK_SPxxK_3	97	104	PF00069	0.581
MOD_CK1_1	24	30	PF00069	0.471
MOD_CK1_1	5	11	PF00069	0.655
MOD_CK2_1	74	80	PF00069	0.482
MOD_GlcNHglycan	101	104	PF01048	0.630
MOD_GlcNHglycan	26	29	PF01048	0.281
MOD_GlcNHglycan	47	50	PF01048	0.282
MOD_GlcNHglycan	91	94	PF01048	0.592
MOD_GSK3_1	45	52	PF00069	0.482
MOD_N-GLC_1	136	141	PF02516	0.666
MOD_N-GLC_1	80	85	PF02516	0.296
MOD_NEK2_1	16	21	PF00069	0.557
MOD_NEK2_1	2	7	PF00069	0.584
MOD_PIKK_1	69	75	PF00454	0.482
MOD_PK_1	3	9	PF00069	0.705
MOD_PKA_2	2	8	PF00069	0.566
MOD_Plk_4	21	27	PF00069	0.417
MOD_ProDKin_1	97	103	PF00069	0.579
TRG_ENDOCYTIC_2	57	60	PF00928	0.562
TRG_Pf-PMV_PEXEL_1	58	63	PF00026	0.386

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDL5	Leptomonas seymouri	78%	99%
A0A0S4IK01	Bodo saltans	70%	87%
A0A1X0NZ24	Trypanosomatidae	83%	100%
A0A3S7X1B7	Leishmania donovani	96%	99%
A0A422N385	Trypanosoma rangeli	84%	100%
A4HGC6	Leishmania braziliensis	95%	99%
A4I3F8	Leishmania infantum	97%	99%
D0A7Y1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	70%	100%
E9AZP7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%