DNA replication licensing factor MCM2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA replication licensing factor MCM2, putative

Species:

Leishmania major

UniProt:

Q4Q8I2_LEIMA

TriTrypDb:

LmjF.28.0850 , LMJLV39_280014600 , LMJSD75_280014600

Length:

969

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	12
GO:0032991	protein-containing complex	1	12
GO:0042555	MCM complex	2	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

Q4Q8I2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8I2

Function

Biological processes
Term	Name	Level	Count
GO:0000724	double-strand break repair via homologous recombination	7	2
GO:0000725	recombinational repair	6	2
GO:0000727	double-strand break repair via break-induced replication	8	2
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006268	DNA unwinding involved in DNA replication	9	12
GO:0006270	DNA replication initiation	5	12
GO:0006281	DNA repair	5	2
GO:0006302	double-strand break repair	6	2
GO:0006310	DNA recombination	5	2
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	2
GO:0006974	DNA damage response	4	2
GO:0006996	organelle organization	4	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0010639	negative regulation of organelle organization	6	12
GO:0016043	cellular component organization	3	12
GO:0022402	cell cycle process	2	2
GO:0032392	DNA geometric change	7	12
GO:0032508	DNA duplex unwinding	8	12
GO:0032780	negative regulation of ATP-dependent activity	4	12
GO:0033043	regulation of organelle organization	5	12
GO:0033044	regulation of chromosome organization	6	12
GO:0033554	cellular response to stress	3	2
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043086	negative regulation of catalytic activity	4	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043462	regulation of ATP-dependent activity	3	12
GO:0044092	negative regulation of molecular function	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0048519	negative regulation of biological process	3	12
GO:0048523	negative regulation of cellular process	4	12
GO:0050789	regulation of biological process	2	12
GO:0050790	regulation of catalytic activity	3	12
GO:0050794	regulation of cellular process	3	12
GO:0050896	response to stimulus	1	2
GO:0051095	regulation of helicase activity	4	12
GO:0051097	negative regulation of helicase activity	5	12
GO:0051128	regulation of cellular component organization	4	12
GO:0051129	negative regulation of cellular component organization	5	12
GO:0051276	chromosome organization	5	12
GO:0051716	cellular response to stimulus	2	2
GO:0065007	biological regulation	1	12
GO:0065009	regulation of molecular function	2	12
GO:0071103	DNA conformation change	6	12
GO:0071704	organic substance metabolic process	2	12
GO:0071840	cellular component organization or biogenesis	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1902292	cell cycle DNA replication initiation	3	2
GO:1902315	nuclear cell cycle DNA replication initiation	4	2
GO:1902975	mitotic DNA replication initiation	4	2
GO:1903047	mitotic cell cycle process	3	2
GO:1905462	regulation of DNA duplex unwinding	7	12
GO:1905463	negative regulation of DNA duplex unwinding	8	12
GO:1905774	regulation of DNA helicase activity	5	12
GO:1905775	negative regulation of DNA helicase activity	6	12
GO:2001251	negative regulation of chromosome organization	7	12
GO:0007049	cell cycle	2	10

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003697	single-stranded DNA binding	5	2
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0016887	ATP hydrolysis activity	7	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0043169	cation binding	3	12
GO:0046872	metal ion binding	4	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	20	24	PF00656	0.785
CLV_C14_Caspase3-7	767	771	PF00656	0.686
CLV_NRD_NRD_1	11	13	PF00675	0.675
CLV_NRD_NRD_1	112	114	PF00675	0.266
CLV_NRD_NRD_1	123	125	PF00675	0.224
CLV_NRD_NRD_1	15	17	PF00675	0.674
CLV_NRD_NRD_1	213	215	PF00675	0.406
CLV_NRD_NRD_1	295	297	PF00675	0.275
CLV_NRD_NRD_1	31	33	PF00675	0.638
CLV_NRD_NRD_1	335	337	PF00675	0.247
CLV_NRD_NRD_1	467	469	PF00675	0.443
CLV_NRD_NRD_1	494	496	PF00675	0.254
CLV_NRD_NRD_1	752	754	PF00675	0.571
CLV_NRD_NRD_1	780	782	PF00675	0.258
CLV_NRD_NRD_1	877	879	PF00675	0.419
CLV_NRD_NRD_1	947	949	PF00675	0.565
CLV_PCSK_FUR_1	11	15	PF00082	0.667
CLV_PCSK_KEX2_1	11	13	PF00082	0.646
CLV_PCSK_KEX2_1	111	113	PF00082	0.264
CLV_PCSK_KEX2_1	123	125	PF00082	0.198
CLV_PCSK_KEX2_1	14	16	PF00082	0.652
CLV_PCSK_KEX2_1	213	215	PF00082	0.406
CLV_PCSK_KEX2_1	31	33	PF00082	0.720
CLV_PCSK_KEX2_1	335	337	PF00082	0.247
CLV_PCSK_KEX2_1	467	469	PF00082	0.454
CLV_PCSK_KEX2_1	752	754	PF00082	0.571
CLV_PCSK_KEX2_1	947	949	PF00082	0.491
CLV_PCSK_PC1ET2_1	13	15	PF00082	0.653
CLV_PCSK_PC7_1	7	13	PF00082	0.681
CLV_PCSK_SKI1_1	214	218	PF00082	0.377
CLV_PCSK_SKI1_1	496	500	PF00082	0.266
CLV_PCSK_SKI1_1	565	569	PF00082	0.238
CLV_PCSK_SKI1_1	697	701	PF00082	0.255
CLV_PCSK_SKI1_1	732	736	PF00082	0.487
CLV_PCSK_SKI1_1	782	786	PF00082	0.247
CLV_PCSK_SKI1_1	878	882	PF00082	0.554
CLV_Separin_Metazoa	210	214	PF03568	0.395
DEG_APCC_DBOX_1	185	193	PF00400	0.591
DEG_APCC_DBOX_1	678	686	PF00400	0.457
DEG_ODPH_VHL_1	502	514	PF01847	0.458
DEG_SCF_FBW7_1	672	678	PF00400	0.447
DOC_CKS1_1	672	677	PF01111	0.454
DOC_CYCLIN_RxL_1	490	501	PF00134	0.478
DOC_MAPK_gen_1	296	304	PF00069	0.458
DOC_MAPK_gen_1	316	325	PF00069	0.316
DOC_MAPK_gen_1	410	419	PF00069	0.447
DOC_MAPK_gen_1	426	435	PF00069	0.509
DOC_MAPK_gen_1	535	542	PF00069	0.447
DOC_MAPK_gen_1	892	899	PF00069	0.508
DOC_MAPK_HePTP_8	506	518	PF00069	0.447
DOC_MAPK_MEF2A_6	297	306	PF00069	0.447
DOC_MAPK_MEF2A_6	319	327	PF00069	0.447
DOC_MAPK_MEF2A_6	410	419	PF00069	0.447
DOC_MAPK_MEF2A_6	509	518	PF00069	0.447
DOC_MAPK_MEF2A_6	535	544	PF00069	0.447
DOC_MAPK_MEF2A_6	687	694	PF00069	0.458
DOC_MAPK_MEF2A_6	815	823	PF00069	0.447
DOC_MAPK_MEF2A_6	892	899	PF00069	0.516
DOC_MAPK_NFAT4_5	509	517	PF00069	0.449
DOC_MAPK_RevD_3	323	336	PF00069	0.447
DOC_PP1_RVXF_1	780	787	PF00149	0.495
DOC_PP2B_LxvP_1	475	478	PF13499	0.418
DOC_USP7_MATH_1	351	355	PF00917	0.496
DOC_USP7_MATH_1	41	45	PF00917	0.496
DOC_USP7_MATH_1	662	666	PF00917	0.488
DOC_USP7_MATH_1	668	672	PF00917	0.502
DOC_USP7_MATH_1	852	856	PF00917	0.542
DOC_USP7_MATH_1	930	934	PF00917	0.553
DOC_USP7_UBL2_3	557	561	PF12436	0.438
DOC_WW_Pin1_4	334	339	PF00397	0.447
DOC_WW_Pin1_4	488	493	PF00397	0.533
DOC_WW_Pin1_4	671	676	PF00397	0.454
LIG_14-3-3_CanoR_1	296	306	PF00244	0.529
LIG_14-3-3_CanoR_1	352	356	PF00244	0.471
LIG_14-3-3_CanoR_1	369	373	PF00244	0.458
LIG_14-3-3_CanoR_1	410	416	PF00244	0.464
LIG_14-3-3_CanoR_1	467	475	PF00244	0.494
LIG_14-3-3_CanoR_1	572	579	PF00244	0.447
LIG_14-3-3_CanoR_1	697	702	PF00244	0.514
LIG_14-3-3_CanoR_1	831	839	PF00244	0.458
LIG_Actin_WH2_2	855	872	PF00022	0.517
LIG_APCC_ABBA_1	232	237	PF00400	0.533
LIG_BIR_III_4	23	27	PF00653	0.680
LIG_BRCT_BRCA1_1	299	303	PF00533	0.533
LIG_BRCT_BRCA1_1	662	666	PF00533	0.458
LIG_BRCT_BRCA1_1	760	764	PF00533	0.621
LIG_BRCT_BRCA1_1	788	792	PF00533	0.533
LIG_BRCT_BRCA1_1	942	946	PF00533	0.410
LIG_Clathr_ClatBox_1	326	330	PF01394	0.447
LIG_FHA_1	286	292	PF00498	0.533
LIG_FHA_1	394	400	PF00498	0.453
LIG_FHA_1	418	424	PF00498	0.447
LIG_FHA_1	455	461	PF00498	0.393
LIG_FHA_1	467	473	PF00498	0.485
LIG_FHA_1	578	584	PF00498	0.440
LIG_FHA_1	629	635	PF00498	0.455
LIG_FHA_1	671	677	PF00498	0.447
LIG_FHA_1	715	721	PF00498	0.627
LIG_FHA_1	849	855	PF00498	0.533
LIG_FHA_1	883	889	PF00498	0.500
LIG_FHA_1	927	933	PF00498	0.394
LIG_FHA_2	662	668	PF00498	0.533
LIG_FHA_2	711	717	PF00498	0.539
LIG_FHA_2	738	744	PF00498	0.498
LIG_FHA_2	844	850	PF00498	0.533
LIG_GBD_Chelix_1	203	211	PF00786	0.427
LIG_Integrin_RGD_1	186	188	PF01839	0.594
LIG_Integrin_RGD_1	363	365	PF01839	0.231
LIG_Integrin_RGD_1	537	539	PF01839	0.247
LIG_LIR_Apic_2	173	179	PF02991	0.716
LIG_LIR_Apic_2	65	69	PF02991	0.476
LIG_LIR_Gen_1	128	138	PF02991	0.487
LIG_LIR_Gen_1	253	261	PF02991	0.450
LIG_LIR_Gen_1	300	311	PF02991	0.576
LIG_LIR_Gen_1	553	563	PF02991	0.447
LIG_LIR_Gen_1	610	619	PF02991	0.447
LIG_LIR_Gen_1	678	686	PF02991	0.447
LIG_LIR_Nem_3	128	134	PF02991	0.487
LIG_LIR_Nem_3	253	257	PF02991	0.449
LIG_LIR_Nem_3	258	264	PF02991	0.449
LIG_LIR_Nem_3	288	292	PF02991	0.533
LIG_LIR_Nem_3	300	306	PF02991	0.522
LIG_LIR_Nem_3	317	321	PF02991	0.356
LIG_LIR_Nem_3	553	558	PF02991	0.447
LIG_LIR_Nem_3	678	683	PF02991	0.447
LIG_LIR_Nem_3	789	795	PF02991	0.533
LIG_LIR_Nem_3	874	880	PF02991	0.432
LIG_LIR_Nem_3	949	953	PF02991	0.413
LIG_LYPXL_S_1	339	343	PF13949	0.247
LIG_LYPXL_yS_3	340	343	PF13949	0.447
LIG_NRBOX	513	519	PF00104	0.458
LIG_PCNA_PIPBox_1	934	943	PF02747	0.535
LIG_PCNA_yPIPBox_3	197	207	PF02747	0.429
LIG_PCNA_yPIPBox_3	773	784	PF02747	0.392
LIG_PCNA_yPIPBox_3	934	948	PF02747	0.540
LIG_PDZ_Class_1	964	969	PF00595	0.454
LIG_Pex14_2	680	684	PF04695	0.447
LIG_Pex14_2	857	861	PF04695	0.447
LIG_PTB_Apo_2	215	222	PF02174	0.315
LIG_PTB_Phospho_1	215	221	PF10480	0.315
LIG_SH2_CRK	225	229	PF00017	0.496
LIG_SH2_CRK	261	265	PF00017	0.447
LIG_SH2_CRK	295	299	PF00017	0.450
LIG_SH2_CRK	950	954	PF00017	0.408
LIG_SH2_GRB2like	224	227	PF00017	0.458
LIG_SH2_NCK_1	941	945	PF00017	0.528
LIG_SH2_PTP2	807	810	PF00017	0.533
LIG_SH2_SRC	355	358	PF00017	0.471
LIG_SH2_SRC	660	663	PF00017	0.458
LIG_SH2_STAP1	235	239	PF00017	0.447
LIG_SH2_STAP1	261	265	PF00017	0.458
LIG_SH2_STAP1	928	932	PF00017	0.550
LIG_SH2_STAT5	184	187	PF00017	0.562
LIG_SH2_STAT5	227	230	PF00017	0.466
LIG_SH2_STAT5	286	289	PF00017	0.447
LIG_SH2_STAT5	355	358	PF00017	0.471
LIG_SH2_STAT5	66	69	PF00017	0.458
LIG_SH2_STAT5	783	786	PF00017	0.447
LIG_SH2_STAT5	807	810	PF00017	0.458
LIG_SH2_STAT5	844	847	PF00017	0.505
LIG_SH2_STAT5	928	931	PF00017	0.557
LIG_SH3_1	335	341	PF00018	0.447
LIG_SH3_2	27	32	PF14604	0.739
LIG_SH3_3	24	30	PF00018	0.737
LIG_SH3_3	267	273	PF00018	0.458
LIG_SH3_3	335	341	PF00018	0.438
LIG_SH3_3	542	548	PF00018	0.447
LIG_SH3_4	773	780	PF00018	0.434
LIG_SUMO_SIM_anti_2	414	420	PF11976	0.447
LIG_SUMO_SIM_par_1	274	282	PF11976	0.460
LIG_SUMO_SIM_par_1	395	401	PF11976	0.458
LIG_SUMO_SIM_par_1	484	489	PF11976	0.509
LIG_SUMO_SIM_par_1	541	547	PF11976	0.447
LIG_TRAF2_1	145	148	PF00917	0.659
LIG_TRAF2_1	429	432	PF00917	0.455
LIG_TRAF2_1	69	72	PF00917	0.502
LIG_TRAF2_1	713	716	PF00917	0.508
LIG_TYR_ITIM	252	257	PF00017	0.299
LIG_UBA3_1	485	490	PF00899	0.315
LIG_UBA3_1	517	526	PF00899	0.299
LIG_WRC_WIRS_1	286	291	PF05994	0.419
LIG_WRC_WIRS_1	698	703	PF05994	0.275
LIG_WW_3	28	32	PF00397	0.756
MOD_CDK_SPxxK_3	488	495	PF00069	0.419
MOD_CK1_1	143	149	PF00069	0.754
MOD_CK1_1	375	381	PF00069	0.315
MOD_CK1_1	671	677	PF00069	0.193
MOD_CK1_1	868	874	PF00069	0.400
MOD_CK1_1	92	98	PF00069	0.315
MOD_CK2_1	230	236	PF00069	0.334
MOD_CK2_1	42	48	PF00069	0.386
MOD_CK2_1	619	625	PF00069	0.299
MOD_CK2_1	710	716	PF00069	0.484
MOD_CK2_1	737	743	PF00069	0.484
MOD_CK2_1	759	765	PF00069	0.642
MOD_CK2_1	868	874	PF00069	0.408
MOD_CK2_1	880	886	PF00069	0.445
MOD_CK2_1	90	96	PF00069	0.419
MOD_GlcNHglycan	44	47	PF01048	0.421
MOD_GlcNHglycan	643	646	PF01048	0.315
MOD_GlcNHglycan	870	873	PF01048	0.419
MOD_GlcNHglycan	909	912	PF01048	0.476
MOD_GlcNHglycan	942	945	PF01048	0.528
MOD_GSK3_1	246	253	PF00069	0.299
MOD_GSK3_1	368	375	PF00069	0.308
MOD_GSK3_1	498	505	PF00069	0.299
MOD_GSK3_1	559	566	PF00069	0.326
MOD_GSK3_1	567	574	PF00069	0.249
MOD_GSK3_1	671	678	PF00069	0.299
MOD_GSK3_1	710	717	PF00069	0.534
MOD_GSK3_1	754	761	PF00069	0.625
MOD_GSK3_1	848	855	PF00069	0.347
MOD_GSK3_1	861	868	PF00069	0.298
MOD_GSK3_1	880	887	PF00069	0.453
MOD_GSK3_1	926	933	PF00069	0.447
MOD_N-GLC_1	668	673	PF02516	0.301
MOD_N-GLC_1	736	741	PF02516	0.498
MOD_N-GLC_1	930	935	PF02516	0.465
MOD_NEK2_1	446	451	PF00069	0.445
MOD_NEK2_1	498	503	PF00069	0.308
MOD_NEK2_1	579	584	PF00069	0.288
MOD_NEK2_1	758	763	PF00069	0.530
MOD_NEK2_1	786	791	PF00069	0.419
MOD_NEK2_1	861	866	PF00069	0.363
MOD_NEK2_2	563	568	PF00069	0.419
MOD_NEK2_2	852	857	PF00069	0.315
MOD_NEK2_2	898	903	PF00069	0.421
MOD_PIKK_1	550	556	PF00454	0.299
MOD_PIKK_1	710	716	PF00454	0.473
MOD_PIKK_1	861	867	PF00454	0.374
MOD_PIKK_1	913	919	PF00454	0.514
MOD_PIKK_1	930	936	PF00454	0.421
MOD_PKA_1	467	473	PF00069	0.570
MOD_PKA_2	1	7	PF00069	0.746
MOD_PKA_2	351	357	PF00069	0.334
MOD_PKA_2	368	374	PF00069	0.315
MOD_PKA_2	386	392	PF00069	0.315
MOD_PKA_2	466	472	PF00069	0.466
MOD_PKA_2	571	577	PF00069	0.299
MOD_PKA_2	619	625	PF00069	0.326
MOD_PKA_2	754	760	PF00069	0.539
MOD_PKA_2	793	799	PF00069	0.299
MOD_PKA_2	830	836	PF00069	0.315
MOD_Plk_1	140	146	PF00069	0.436
MOD_Plk_1	230	236	PF00069	0.390
MOD_Plk_1	246	252	PF00069	0.189
MOD_Plk_1	563	569	PF00069	0.404
MOD_Plk_1	618	624	PF00069	0.315
MOD_Plk_1	668	674	PF00069	0.193
MOD_Plk_1	714	720	PF00069	0.655
MOD_Plk_1	726	732	PF00069	0.485
MOD_Plk_1	759	765	PF00069	0.665
MOD_Plk_1	89	95	PF00069	0.343
MOD_Plk_2-3	613	619	PF00069	0.299
MOD_Plk_2-3	843	849	PF00069	0.419
MOD_Plk_2-3	90	96	PF00069	0.419
MOD_Plk_4	230	236	PF00069	0.334
MOD_Plk_4	260	266	PF00069	0.302
MOD_Plk_4	351	357	PF00069	0.303
MOD_Plk_4	393	399	PF00069	0.306
MOD_Plk_4	455	461	PF00069	0.393
MOD_Plk_4	697	703	PF00069	0.275
MOD_Plk_4	825	831	PF00069	0.299
MOD_Plk_4	852	858	PF00069	0.446
MOD_ProDKin_1	334	340	PF00069	0.299
MOD_ProDKin_1	488	494	PF00069	0.419
MOD_ProDKin_1	671	677	PF00069	0.309
MOD_SUMO_rev_2	231	239	PF00179	0.340
MOD_SUMO_rev_2	505	514	PF00179	0.299
TRG_DiLeu_BaEn_1	595	600	PF01217	0.299
TRG_DiLeu_BaEn_1	715	720	PF01217	0.653
TRG_DiLeu_BaEn_4	121	127	PF01217	0.347
TRG_DiLeu_BaEn_4	52	58	PF01217	0.417
TRG_DiLeu_BaEn_4	715	721	PF01217	0.627
TRG_DiLeu_BaEn_4	726	732	PF01217	0.567
TRG_DiLeu_BaLyEn_6	442	447	PF01217	0.435
TRG_DiLeu_BaLyEn_6	948	953	PF01217	0.538
TRG_DiLeu_LyEn_5	715	720	PF01217	0.653
TRG_DiLeu_LyEn_5	886	891	PF01217	0.460
TRG_ENDOCYTIC_2	225	228	PF00928	0.368
TRG_ENDOCYTIC_2	254	257	PF00928	0.299
TRG_ENDOCYTIC_2	261	264	PF00928	0.299
TRG_ENDOCYTIC_2	286	289	PF00928	0.301
TRG_ENDOCYTIC_2	295	298	PF00928	0.295
TRG_ENDOCYTIC_2	340	343	PF00928	0.298
TRG_ENDOCYTIC_2	783	786	PF00928	0.384
TRG_ENDOCYTIC_2	807	810	PF00928	0.299
TRG_ENDOCYTIC_2	950	953	PF00928	0.404
TRG_ER_diArg_1	11	14	PF00400	0.686
TRG_ER_diArg_1	111	113	PF00400	0.394
TRG_ER_diArg_1	212	214	PF00400	0.405
TRG_ER_diArg_1	30	32	PF00400	0.540
TRG_ER_diArg_1	334	336	PF00400	0.299
TRG_ER_diArg_1	466	468	PF00400	0.430
TRG_ER_diArg_1	482	485	PF00400	0.257
TRG_ER_diArg_1	730	733	PF00400	0.542
TRG_ER_diArg_1	751	753	PF00400	0.530
TRG_ER_diArg_1	891	894	PF00400	0.532
TRG_ER_diArg_1	946	948	PF00400	0.335
TRG_ER_FFAT_2	921	933	PF00635	0.577
TRG_NES_CRM1_1	681	696	PF08389	0.315
TRG_NLS_MonoCore_2	11	16	PF00514	0.719
TRG_NLS_MonoExtC_3	11	16	PF00514	0.719
TRG_NLS_MonoExtN_4	11	17	PF00514	0.732
TRG_NLS_MonoExtN_4	492	499	PF00514	0.277
TRG_Pf-PMV_PEXEL_1	124	128	PF00026	0.373
TRG_Pf-PMV_PEXEL_1	718	723	PF00026	0.525
TRG_Pf-PMV_PEXEL_1	752	756	PF00026	0.553
TRG_Pf-PMV_PEXEL_1	951	955	PF00026	0.536

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P860	Leptomonas seymouri	87%	98%
A0A0N1I383	Leptomonas seymouri	32%	95%
A0A0S4IK09	Bodo saltans	64%	98%
A0A1X0NZT6	Trypanosomatidae	75%	100%
A0A3Q8IAX4	Leishmania donovani	98%	100%
A0A3R7K9K0	Trypanosoma rangeli	31%	100%
A0A3R7NBN0	Trypanosoma rangeli	76%	100%
A0A3S7WY81	Leishmania donovani	30%	100%
A0A3S7X726	Leishmania donovani	32%	100%
A0A422NDD9	Trypanosoma rangeli	29%	100%
A4FUD9	Bos taurus	33%	100%
A4H5K0	Leishmania braziliensis	32%	100%
A4HDE7	Leishmania braziliensis	30%	100%
A4HGC9	Leishmania braziliensis	92%	100%
A4HLY1	Leishmania braziliensis	32%	100%
A4I0T0	Leishmania infantum	30%	100%
A4I3G2	Leishmania infantum	98%	100%
A4I9B0	Leishmania infantum	32%	100%
B8AZ99	Oryza sativa subsp. indica	34%	100%
B8BKI8	Oryza sativa subsp. indica	46%	100%
D0A7X6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
E9AMM4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AWT2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9AZQ1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
E9B4B0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
F1M5F3	Rattus norvegicus	31%	86%
F1N2W9	Bos taurus	31%	85%
F6RIX4	Xenopus tropicalis	30%	87%
P25205	Homo sapiens	34%	100%
P25206	Mus musculus	33%	100%
P29469	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	47%	100%
P30666	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
P33991	Homo sapiens	31%	100%
P40377	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	100%
P41389	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	100%
P49731	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	100%
P49735	Drosophila melanogaster	43%	100%
P49736	Homo sapiens	45%	100%
P55861	Xenopus laevis	40%	100%
P97310	Mus musculus	44%	100%
Q0DHC4	Oryza sativa subsp. japonica	34%	100%
Q21902	Caenorhabditis elegans	29%	100%
Q28BS0	Xenopus tropicalis	34%	100%
Q29JI9	Drosophila pseudoobscura pseudoobscura	31%	100%
Q2KHI9	Mus musculus	32%	85%
Q2R482	Oryza sativa subsp. japonica	46%	100%
Q43704	Zea mays	34%	100%
Q4Q3R6	Leishmania major	32%	100%
Q4QAP2	Leishmania major	30%	100%
Q4QI01	Leishmania major	31%	100%
Q54CP4	Dictyostelium discoideum	31%	100%
Q5R8G6	Pongo abelii	34%	100%
Q6DIH3	Xenopus tropicalis	42%	100%
Q6NRM6	Xenopus laevis	30%	85%
Q7ZXZ0	Xenopus laevis	35%	100%
Q9LPD9	Arabidopsis thaliana	41%	100%
Q9NXL9	Homo sapiens	31%	85%
Q9SF37	Arabidopsis thaliana	31%	100%
Q9SX03	Zea mays	34%	100%
Q9SX04	Zea mays	34%	100%
Q9V461	Drosophila melanogaster	32%	100%
Q9VGW6	Drosophila melanogaster	31%	100%
Q9XYU0	Drosophila melanogaster	32%	100%
Q9XYU1	Drosophila melanogaster	34%	100%
V5BQA9	Trypanosoma cruzi	80%	100%
V5BSG2	Trypanosoma cruzi	30%	100%