DRBM domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q8G7_LEIMA

TriTrypDb:

LmjF.28.1000 , LMJLV39_280016300 , LMJSD75_280016300

Length:

939

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q8G7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8G7

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	859	863	PF00656	0.709
CLV_NRD_NRD_1	193	195	PF00675	0.704
CLV_NRD_NRD_1	197	199	PF00675	0.625
CLV_NRD_NRD_1	496	498	PF00675	0.447
CLV_NRD_NRD_1	749	751	PF00675	0.514
CLV_NRD_NRD_1	769	771	PF00675	0.278
CLV_NRD_NRD_1	788	790	PF00675	0.282
CLV_NRD_NRD_1	797	799	PF00675	0.385
CLV_PCSK_FUR_1	494	498	PF00082	0.473
CLV_PCSK_KEX2_1	193	195	PF00082	0.656

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2W5	Leptomonas seymouri	49%	89%
A0A1X0NZW9	Trypanosomatidae	35%	95%
A0A3Q8IDR2	Leishmania donovani	94%	100%
A0A3R7M3D8	Trypanosoma rangeli	35%	100%
A4HGE4	Leishmania braziliensis	76%	90%
A4I3H7	Leishmania infantum	94%	100%
E9AZR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
V5D1P8	Trypanosoma cruzi	35%	100%

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