Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q8G1_LEIMA

TriTrypDb:

LmjF.28.1060 , LMJLV39_280016900 , LMJSD75_280016700

Length:

405

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q8G1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8G1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	13	17	PF00656	0.727
CLV_NRD_NRD_1	140	142	PF00675	0.595
CLV_NRD_NRD_1	145	147	PF00675	0.598
CLV_NRD_NRD_1	210	212	PF00675	0.698
CLV_NRD_NRD_1	24	26	PF00675	0.633
CLV_NRD_NRD_1	249	251	PF00675	0.747
CLV_NRD_NRD_1	350	352	PF00675	0.744
CLV_NRD_NRD_1	87	89	PF00675	0.645
CLV_PCSK_FUR_1	208	212	PF00082	0.721
CLV_PCSK_KEX2_1	140	142	PF00082	0.595
CLV_PCSK_KEX2_1	19	21	PF00082	0.614
CLV_PCSK_KEX2_1	210	212	PF00082	0.697
CLV_PCSK_KEX2_1	24	26	PF00082	0.613
CLV_PCSK_KEX2_1	350	352	PF00082	0.744
CLV_PCSK_KEX2_1	86	88	PF00082	0.647
CLV_PCSK_PC1ET2_1	19	21	PF00082	0.668
CLV_PCSK_PC7_1	15	21	PF00082	0.614
CLV_PCSK_SKI1_1	184	188	PF00082	0.619
DEG_COP1_1	130	137	PF00400	0.665
DEG_Nend_Nbox_1	1	3	PF02207	0.589
DOC_PP4_FxxP_1	258	261	PF00568	0.690
DOC_USP7_MATH_1	119	123	PF00917	0.765
DOC_USP7_MATH_1	185	189	PF00917	0.781
DOC_USP7_MATH_1	225	229	PF00917	0.762
DOC_USP7_MATH_1	252	256	PF00917	0.690
DOC_USP7_UBL2_3	284	288	PF12436	0.685
DOC_WW_Pin1_4	213	218	PF00397	0.724
DOC_WW_Pin1_4	257	262	PF00397	0.639
DOC_WW_Pin1_4	289	294	PF00397	0.706
DOC_WW_Pin1_4	374	379	PF00397	0.755
LIG_14-3-3_CanoR_1	123	127	PF00244	0.695
LIG_14-3-3_CanoR_1	221	225	PF00244	0.631
LIG_APCC_ABBA_1	325	330	PF00400	0.557
LIG_BRCT_BRCA1_1	254	258	PF00533	0.690
LIG_FHA_1	123	129	PF00498	0.648
LIG_FHA_1	176	182	PF00498	0.792
LIG_FHA_1	5	11	PF00498	0.700
LIG_FHA_2	134	140	PF00498	0.593
LIG_FHA_2	148	154	PF00498	0.580
LIG_LIR_Apic_2	255	261	PF02991	0.681
LIG_LIR_Gen_1	153	163	PF02991	0.594
LIG_LIR_Nem_3	153	159	PF02991	0.585
LIG_MYND_1	401	405	PF01753	0.583
LIG_SH2_GRB2like	302	305	PF00017	0.721
LIG_SH2_SRC	302	305	PF00017	0.615
LIG_SH2_SRC	333	336	PF00017	0.646
LIG_SH2_STAP1	362	366	PF00017	0.696
LIG_SH2_STAP1	395	399	PF00017	0.665
LIG_SH2_STAT3	316	319	PF00017	0.618
LIG_SH2_STAT5	296	299	PF00017	0.653
LIG_SH3_1	201	207	PF00018	0.624
LIG_SH3_3	157	163	PF00018	0.530
LIG_SH3_3	201	207	PF00018	0.642
LIG_SH3_3	277	283	PF00018	0.589
LIG_SH3_3	42	48	PF00018	0.706
LIG_SH3_4	284	291	PF00018	0.688
MOD_CK1_1	122	128	PF00069	0.748
MOD_CK1_1	151	157	PF00069	0.514
MOD_CK1_1	81	87	PF00069	0.742
MOD_CK2_1	147	153	PF00069	0.570
MOD_CK2_1	220	226	PF00069	0.819
MOD_CK2_1	374	380	PF00069	0.691
MOD_Cter_Amidation	208	211	PF01082	0.697
MOD_Cter_Amidation	22	25	PF01082	0.613
MOD_GlcNHglycan	119	122	PF01048	0.738
MOD_GlcNHglycan	153	156	PF01048	0.691
MOD_GlcNHglycan	181	184	PF01048	0.775
MOD_GlcNHglycan	21	24	PF01048	0.733
MOD_GlcNHglycan	226	230	PF01048	0.765
MOD_GlcNHglycan	75	78	PF01048	0.663
MOD_GlcNHglycan	80	83	PF01048	0.772
MOD_GlcNHglycan	89	92	PF01048	0.619
MOD_GSK3_1	147	154	PF00069	0.652
MOD_GSK3_1	175	182	PF00069	0.828
MOD_GSK3_1	215	222	PF00069	0.724
MOD_GSK3_1	78	85	PF00069	0.799
MOD_GSK3_1	97	104	PF00069	0.520
MOD_N-GLC_1	128	133	PF02516	0.631
MOD_N-GLC_1	197	202	PF02516	0.575
MOD_N-GLC_1	219	224	PF02516	0.721
MOD_NEK2_1	361	366	PF00069	0.693
MOD_PIKK_1	122	128	PF00454	0.719
MOD_PIKK_1	162	168	PF00454	0.555
MOD_PKA_1	19	25	PF00069	0.613
MOD_PKA_1	87	93	PF00069	0.680
MOD_PKA_2	122	128	PF00069	0.760
MOD_PKA_2	19	25	PF00069	0.613
MOD_PKA_2	220	226	PF00069	0.635
MOD_PKA_2	305	311	PF00069	0.743
MOD_PKA_2	87	93	PF00069	0.680
MOD_Plk_1	219	225	PF00069	0.760
MOD_Plk_1	362	368	PF00069	0.664
MOD_Plk_4	63	69	PF00069	0.541
MOD_ProDKin_1	213	219	PF00069	0.723
MOD_ProDKin_1	257	263	PF00069	0.635
MOD_ProDKin_1	289	295	PF00069	0.706
MOD_ProDKin_1	374	380	PF00069	0.755
TRG_ER_diArg_1	207	210	PF00400	0.711
TRG_ER_diArg_1	86	88	PF00400	0.764

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P454	Leptomonas seymouri	41%	100%
A0A3S7X1G1	Leishmania donovani	91%	100%
A4HGF0	Leishmania braziliensis	62%	100%
A4I3I1	Leishmania infantum	91%	100%
E9AZS3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	99%