DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

helicase-like protein

Species:

Leishmania major

UniProt:

Q4Q8A5_LEIMA

TriTrypDb:

LmjF.28.1600 , LMJLV39_280023800 , LMJSD75_280023300

Length:

1127

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	11
GO:0016020	membrane	2	7
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11

Expansion

Sequence features

Q4Q8A5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q8A5

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	2
GO:0006281	DNA repair	5	2
GO:0006289	nucleotide-excision repair	6	2
GO:0006302	double-strand break repair	6	2
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	2
GO:0006974	DNA damage response	4	2
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0022402	cell cycle process	2	2
GO:0022414	reproductive process	1	2
GO:0033554	cellular response to stress	3	2
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0046483	heterocycle metabolic process	3	12
GO:0050896	response to stimulus	1	2
GO:0051716	cellular response to stimulus	2	2
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1903046	meiotic cell cycle process	2	2
GO:1990918	double-strand break repair involved in meiotic recombination	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0016462	pyrophosphatase activity	5	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1036	1040	PF00656	0.738
CLV_C14_Caspase3-7	164	168	PF00656	0.720
CLV_C14_Caspase3-7	629	633	PF00656	0.591
CLV_NRD_NRD_1	111	113	PF00675	0.337
CLV_NRD_NRD_1	118	120	PF00675	0.498
CLV_NRD_NRD_1	124	126	PF00675	0.487
CLV_NRD_NRD_1	184	186	PF00675	0.488
CLV_NRD_NRD_1	201	203	PF00675	0.265
CLV_NRD_NRD_1	228	230	PF00675	0.246
CLV_NRD_NRD_1	474	476	PF00675	0.715
CLV_NRD_NRD_1	511	513	PF00675	0.571
CLV_NRD_NRD_1	814	816	PF00675	0.305
CLV_NRD_NRD_1	960	962	PF00675	0.384
CLV_NRD_NRD_1	97	99	PF00675	0.476
CLV_PCSK_FUR_1	109	113	PF00082	0.413
CLV_PCSK_FUR_1	472	476	PF00082	0.629
CLV_PCSK_KEX2_1	111	113	PF00082	0.353
CLV_PCSK_KEX2_1	118	120	PF00082	0.499
CLV_PCSK_KEX2_1	124	126	PF00082	0.489
CLV_PCSK_KEX2_1	200	202	PF00082	0.394
CLV_PCSK_KEX2_1	228	230	PF00082	0.294
CLV_PCSK_KEX2_1	474	476	PF00082	0.694
CLV_PCSK_KEX2_1	478	480	PF00082	0.709
CLV_PCSK_KEX2_1	511	513	PF00082	0.602
CLV_PCSK_KEX2_1	572	574	PF00082	0.260
CLV_PCSK_KEX2_1	960	962	PF00082	0.361
CLV_PCSK_KEX2_1	97	99	PF00082	0.425
CLV_PCSK_PC1ET2_1	124	126	PF00082	0.565
CLV_PCSK_PC1ET2_1	478	480	PF00082	0.747
CLV_PCSK_PC1ET2_1	572	574	PF00082	0.260
CLV_PCSK_PC1ET2_1	97	99	PF00082	0.423
CLV_PCSK_PC7_1	474	480	PF00082	0.700
CLV_PCSK_SKI1_1	1096	1100	PF00082	0.442
CLV_PCSK_SKI1_1	1108	1112	PF00082	0.428
CLV_PCSK_SKI1_1	201	205	PF00082	0.443
CLV_PCSK_SKI1_1	389	393	PF00082	0.328
CLV_PCSK_SKI1_1	573	577	PF00082	0.269
CLV_PCSK_SKI1_1	579	583	PF00082	0.297
CLV_PCSK_SKI1_1	610	614	PF00082	0.497
CLV_PCSK_SKI1_1	626	630	PF00082	0.346
CLV_PCSK_SKI1_1	667	671	PF00082	0.285
CLV_PCSK_SKI1_1	787	791	PF00082	0.326
CLV_PCSK_SKI1_1	861	865	PF00082	0.326
CLV_PCSK_SKI1_1	907	911	PF00082	0.332
CLV_PCSK_SKI1_1	960	964	PF00082	0.415
DEG_APCC_DBOX_1	388	396	PF00400	0.512
DEG_SCF_TRCP1_1	632	638	PF00400	0.662
DEG_SPOP_SBC_1	416	420	PF00917	0.699
DEG_SPOP_SBC_1	715	719	PF00917	0.605
DOC_CDC14_PxL_1	340	348	PF14671	0.544
DOC_CKS1_1	42	47	PF01111	0.624
DOC_CKS1_1	973	978	PF01111	0.685
DOC_CYCLIN_RxL_1	432	443	PF00134	0.595
DOC_CYCLIN_yCln2_LP_2	39	45	PF00134	0.631
DOC_CYCLIN_yCln2_LP_2	741	747	PF00134	0.554
DOC_CYCLIN_yCln2_LP_2	866	872	PF00134	0.544
DOC_MAPK_gen_1	185	193	PF00069	0.671
DOC_MAPK_gen_1	572	580	PF00069	0.468
DOC_MAPK_gen_1	784	792	PF00069	0.508
DOC_MAPK_gen_1	846	855	PF00069	0.449
DOC_MAPK_gen_1	907	917	PF00069	0.469
DOC_MAPK_MEF2A_6	389	396	PF00069	0.578
DOC_MAPK_MEF2A_6	572	580	PF00069	0.482
DOC_MAPK_MEF2A_6	861	870	PF00069	0.444
DOC_MAPK_NFAT4_5	389	397	PF00069	0.580
DOC_MAPK_NFAT4_5	573	581	PF00069	0.557
DOC_MAPK_NFAT4_5	861	869	PF00069	0.508
DOC_MAPK_RevD_3	802	816	PF00069	0.393
DOC_PP1_RVXF_1	328	335	PF00149	0.455
DOC_PP2B_LxvP_1	1016	1019	PF13499	0.684
DOC_PP2B_LxvP_1	204	207	PF13499	0.585
DOC_PP2B_LxvP_1	39	42	PF13499	0.615
DOC_PP2B_LxvP_1	771	774	PF13499	0.470
DOC_PP2B_LxvP_1	866	869	PF13499	0.544
DOC_PP4_FxxP_1	203	206	PF00568	0.618
DOC_PP4_FxxP_1	531	534	PF00568	0.416
DOC_PP4_FxxP_1	811	814	PF00568	0.469
DOC_USP7_MATH_1	1035	1039	PF00917	0.824
DOC_USP7_MATH_1	1042	1046	PF00917	0.637
DOC_USP7_MATH_1	1061	1065	PF00917	0.723
DOC_USP7_MATH_1	1102	1106	PF00917	0.702
DOC_USP7_MATH_1	14	18	PF00917	0.795
DOC_USP7_MATH_1	233	237	PF00917	0.393
DOC_USP7_MATH_1	401	405	PF00917	0.596
DOC_USP7_MATH_1	416	420	PF00917	0.684
DOC_USP7_MATH_1	594	598	PF00917	0.581
DOC_USP7_MATH_1	601	605	PF00917	0.640
DOC_USP7_MATH_1	715	719	PF00917	0.686
DOC_USP7_MATH_1	872	876	PF00917	0.455
DOC_USP7_MATH_1	974	978	PF00917	0.771
DOC_USP7_UBL2_3	126	130	PF12436	0.715
DOC_WW_Pin1_4	10	15	PF00397	0.718
DOC_WW_Pin1_4	1038	1043	PF00397	0.787
DOC_WW_Pin1_4	1071	1076	PF00397	0.701
DOC_WW_Pin1_4	22	27	PF00397	0.678
DOC_WW_Pin1_4	41	46	PF00397	0.548
DOC_WW_Pin1_4	61	66	PF00397	0.473
DOC_WW_Pin1_4	673	678	PF00397	0.557
DOC_WW_Pin1_4	966	971	PF00397	0.652
DOC_WW_Pin1_4	97	102	PF00397	0.574
DOC_WW_Pin1_4	972	977	PF00397	0.652
LIG_14-3-3_CanoR_1	1024	1030	PF00244	0.760
LIG_14-3-3_CanoR_1	1049	1055	PF00244	0.731
LIG_14-3-3_CanoR_1	1062	1072	PF00244	0.654
LIG_14-3-3_CanoR_1	180	187	PF00244	0.712
LIG_14-3-3_CanoR_1	522	531	PF00244	0.487
LIG_14-3-3_CanoR_1	735	739	PF00244	0.584
LIG_14-3-3_CanoR_1	846	855	PF00244	0.473
LIG_14-3-3_CanoR_1	936	940	PF00244	0.619
LIG_14-3-3_CanoR_1	953	963	PF00244	0.608
LIG_Actin_WH2_2	206	223	PF00022	0.508
LIG_Actin_WH2_2	649	665	PF00022	0.520
LIG_Actin_WH2_2	747	764	PF00022	0.583
LIG_Actin_WH2_2	891	909	PF00022	0.503
LIG_APCC_ABBA_1	366	371	PF00400	0.455
LIG_APCC_ABBA_1	458	463	PF00400	0.337
LIG_BRCT_BRCA1_1	458	462	PF00533	0.295
LIG_BRCT_BRCA1_1	654	658	PF00533	0.470
LIG_deltaCOP1_diTrp_1	167	176	PF00928	0.546
LIG_EH_1	558	562	PF12763	0.283
LIG_eIF4E_1	327	333	PF01652	0.436
LIG_eIF4E_1	345	351	PF01652	0.455
LIG_eIF4E_1	912	918	PF01652	0.452
LIG_EVH1_2	172	176	PF00568	0.599
LIG_FHA_1	1005	1011	PF00498	0.730
LIG_FHA_1	1089	1095	PF00498	0.699
LIG_FHA_1	232	238	PF00498	0.551
LIG_FHA_1	260	266	PF00498	0.456
LIG_FHA_1	36	42	PF00498	0.654
LIG_FHA_1	418	424	PF00498	0.731
LIG_FHA_1	636	642	PF00498	0.703
LIG_FHA_1	644	650	PF00498	0.524
LIG_FHA_1	756	762	PF00498	0.512
LIG_FHA_1	784	790	PF00498	0.511
LIG_FHA_1	80	86	PF00498	0.494
LIG_FHA_1	819	825	PF00498	0.513
LIG_FHA_1	836	842	PF00498	0.414
LIG_FHA_1	890	896	PF00498	0.510
LIG_FHA_2	1034	1040	PF00498	0.766
LIG_FHA_2	159	165	PF00498	0.751
LIG_FHA_2	353	359	PF00498	0.555
LIG_FHA_2	441	447	PF00498	0.299
LIG_FHA_2	502	508	PF00498	0.406
LIG_FHA_2	627	633	PF00498	0.591
LIG_FHA_2	758	764	PF00498	0.552
LIG_Integrin_isoDGR_2	492	494	PF01839	0.663
LIG_Integrin_RGD_1	481	483	PF01839	0.665
LIG_LIR_Apic_2	167	172	PF02991	0.572
LIG_LIR_Apic_2	597	601	PF02991	0.615
LIG_LIR_Apic_2	808	814	PF02991	0.535
LIG_LIR_Apic_2	919	925	PF02991	0.508
LIG_LIR_Gen_1	287	297	PF02991	0.487
LIG_LIR_Gen_1	427	434	PF02991	0.658
LIG_LIR_Gen_1	446	455	PF02991	0.225
LIG_LIR_Gen_1	655	665	PF02991	0.493
LIG_LIR_Gen_1	737	746	PF02991	0.546
LIG_LIR_Nem_3	174	179	PF02991	0.549
LIG_LIR_Nem_3	287	292	PF02991	0.487
LIG_LIR_Nem_3	337	343	PF02991	0.507
LIG_LIR_Nem_3	446	451	PF02991	0.310
LIG_LIR_Nem_3	459	464	PF02991	0.308
LIG_LIR_Nem_3	557	561	PF02991	0.283
LIG_LIR_Nem_3	655	661	PF02991	0.474
LIG_LIR_Nem_3	676	681	PF02991	0.571
LIG_LIR_Nem_3	690	695	PF02991	0.444
LIG_LIR_Nem_3	737	741	PF02991	0.560
LIG_LIR_Nem_3	875	879	PF02991	0.491
LIG_LIR_Nem_3	911	915	PF02991	0.452
LIG_LYPXL_yS_3	343	346	PF13949	0.544
LIG_MLH1_MIPbox_1	458	462	PF16413	0.295
LIG_MYND_1	729	733	PF01753	0.573
LIG_NRBOX	577	583	PF00104	0.543
LIG_Pex14_1	959	963	PF04695	0.585
LIG_Pex14_2	175	179	PF04695	0.548
LIG_PTB_Apo_2	740	747	PF02174	0.589
LIG_REV1ctd_RIR_1	173	181	PF16727	0.579
LIG_SH2_CRK	548	552	PF00017	0.244
LIG_SH2_CRK	738	742	PF00017	0.539
LIG_SH2_CRK	776	780	PF00017	0.533
LIG_SH2_CRK	912	916	PF00017	0.470
LIG_SH2_NCK_1	1085	1089	PF00017	0.650
LIG_SH2_NCK_1	335	339	PF00017	0.495
LIG_SH2_NCK_1	922	926	PF00017	0.510
LIG_SH2_SRC	335	338	PF00017	0.532
LIG_SH2_STAP1	1085	1089	PF00017	0.709
LIG_SH2_STAP1	706	710	PF00017	0.539
LIG_SH2_STAP1	890	894	PF00017	0.510
LIG_SH2_STAT3	107	110	PF00017	0.569
LIG_SH2_STAT3	46	49	PF00017	0.515
LIG_SH2_STAT5	107	110	PF00017	0.643
LIG_SH2_STAT5	212	215	PF00017	0.483
LIG_SH2_STAT5	248	251	PF00017	0.475
LIG_SH2_STAT5	345	348	PF00017	0.460
LIG_SH2_STAT5	890	893	PF00017	0.455
LIG_SH3_2	869	874	PF14604	0.452
LIG_SH3_3	1019	1025	PF00018	0.681
LIG_SH3_3	25	31	PF00018	0.747
LIG_SH3_3	39	45	PF00018	0.572
LIG_SH3_3	697	703	PF00018	0.573
LIG_SH3_3	70	76	PF00018	0.569
LIG_SH3_3	801	807	PF00018	0.519
LIG_SH3_3	866	872	PF00018	0.452
LIG_SUMO_SIM_anti_2	390	398	PF11976	0.458
LIG_SUMO_SIM_anti_2	788	793	PF11976	0.489
LIG_SUMO_SIM_par_1	443	449	PF11976	0.341
LIG_SUMO_SIM_par_1	914	920	PF11976	0.444
LIG_TRAF2_1	1116	1119	PF00917	0.757
LIG_TRFH_1	345	349	PF08558	0.444
LIG_TYR_ITIM	333	338	PF00017	0.485
LIG_UBA3_1	577	584	PF00899	0.522
LIG_WRC_WIRS_1	447	452	PF05994	0.402
MOD_CDC14_SPxK_1	1041	1044	PF00782	0.663
MOD_CDK_SPK_2	97	102	PF00069	0.649
MOD_CDK_SPxK_1	1038	1044	PF00069	0.670
MOD_CK1_1	1033	1039	PF00069	0.810
MOD_CK1_1	1113	1119	PF00069	0.716
MOD_CK1_1	415	421	PF00069	0.730
MOD_CK1_1	717	723	PF00069	0.709
MOD_CK2_1	1113	1119	PF00069	0.732
MOD_CK2_1	158	164	PF00069	0.747
MOD_CK2_1	352	358	PF00069	0.556
MOD_CK2_1	440	446	PF00069	0.299
MOD_CK2_1	501	507	PF00069	0.396
MOD_CK2_1	603	609	PF00069	0.713
MOD_CK2_1	757	763	PF00069	0.596
MOD_CK2_1	97	103	PF00069	0.550
MOD_Cter_Amidation	472	475	PF01082	0.600
MOD_GlcNHglycan	1019	1022	PF01048	0.505
MOD_GlcNHglycan	1044	1047	PF01048	0.505
MOD_GlcNHglycan	1063	1066	PF01048	0.494
MOD_GlcNHglycan	1067	1070	PF01048	0.530
MOD_GlcNHglycan	1112	1116	PF01048	0.506
MOD_GlcNHglycan	120	123	PF01048	0.529
MOD_GlcNHglycan	18	21	PF01048	0.552
MOD_GlcNHglycan	294	297	PF01048	0.318
MOD_GlcNHglycan	35	38	PF01048	0.390
MOD_GlcNHglycan	414	417	PF01048	0.525
MOD_GlcNHglycan	5	8	PF01048	0.571
MOD_GlcNHglycan	603	606	PF01048	0.507
MOD_GlcNHglycan	61	64	PF01048	0.403
MOD_GlcNHglycan	616	619	PF01048	0.542
MOD_GlcNHglycan	632	635	PF01048	0.520
MOD_GlcNHglycan	671	674	PF01048	0.273
MOD_GlcNHglycan	763	767	PF01048	0.331
MOD_GlcNHglycan	884	887	PF01048	0.244
MOD_GlcNHglycan	976	979	PF01048	0.526
MOD_GSK3_1	10	17	PF00069	0.734
MOD_GSK3_1	1033	1040	PF00069	0.769
MOD_GSK3_1	1061	1068	PF00069	0.698
MOD_GSK3_1	1084	1091	PF00069	0.661
MOD_GSK3_1	167	174	PF00069	0.676
MOD_GSK3_1	22	29	PF00069	0.725
MOD_GSK3_1	412	419	PF00069	0.728
MOD_GSK3_1	601	608	PF00069	0.702
MOD_GSK3_1	622	629	PF00069	0.710
MOD_GSK3_1	652	659	PF00069	0.550
MOD_GSK3_1	669	676	PF00069	0.451
MOD_GSK3_1	687	694	PF00069	0.569
MOD_GSK3_1	714	721	PF00069	0.636
MOD_GSK3_1	723	730	PF00069	0.667
MOD_GSK3_1	757	764	PF00069	0.534
MOD_GSK3_1	968	975	PF00069	0.711
MOD_LATS_1	116	122	PF00433	0.793
MOD_LATS_1	178	184	PF00433	0.656
MOD_N-GLC_1	259	264	PF02516	0.306
MOD_N-GLC_1	722	727	PF02516	0.478
MOD_N-GLC_1	828	833	PF02516	0.350
MOD_N-GLC_1	853	858	PF02516	0.375
MOD_N-GLC_2	339	341	PF02516	0.310
MOD_NEK2_1	1050	1055	PF00069	0.717
MOD_NEK2_1	1076	1081	PF00069	0.640
MOD_NEK2_1	1084	1089	PF00069	0.649
MOD_NEK2_1	1110	1115	PF00069	0.737
MOD_NEK2_1	15	20	PF00069	0.777
MOD_NEK2_1	292	297	PF00069	0.510
MOD_NEK2_1	316	321	PF00069	0.544
MOD_NEK2_1	33	38	PF00069	0.640
MOD_NEK2_1	454	459	PF00069	0.418
MOD_NEK2_1	501	506	PF00069	0.389
MOD_NEK2_1	52	57	PF00069	0.437
MOD_NEK2_1	554	559	PF00069	0.283
MOD_NEK2_1	561	566	PF00069	0.283
MOD_NEK2_1	652	657	PF00069	0.475
MOD_NEK2_1	661	666	PF00069	0.492
MOD_NEK2_1	734	739	PF00069	0.570
MOD_NEK2_1	746	751	PF00069	0.537
MOD_NEK2_1	757	762	PF00069	0.521
MOD_NEK2_1	840	845	PF00069	0.529
MOD_NEK2_1	85	90	PF00069	0.513
MOD_NEK2_1	952	957	PF00069	0.542
MOD_NEK2_2	233	238	PF00069	0.393
MOD_PIKK_1	193	199	PF00454	0.633
MOD_PIKK_1	501	507	PF00454	0.452
MOD_PIKK_1	701	707	PF00454	0.632
MOD_PIKK_1	724	730	PF00454	0.727
MOD_PIKK_1	755	761	PF00454	0.564
MOD_PIKK_1	805	811	PF00454	0.503
MOD_PIKK_1	828	834	PF00454	0.552
MOD_PIKK_1	954	960	PF00454	0.494
MOD_PKA_1	118	124	PF00069	0.752
MOD_PKA_2	1061	1067	PF00069	0.728
MOD_PKA_2	118	124	PF00069	0.773
MOD_PKA_2	734	740	PF00069	0.598
MOD_PKA_2	761	767	PF00069	0.524
MOD_PKA_2	929	935	PF00069	0.486
MOD_PKA_2	952	958	PF00069	0.625
MOD_PKB_1	1002	1010	PF00069	0.736
MOD_Plk_1	259	265	PF00069	0.494
MOD_Plk_1	608	614	PF00069	0.758
MOD_Plk_1	687	693	PF00069	0.579
MOD_Plk_1	941	947	PF00069	0.588
MOD_Plk_2-3	158	164	PF00069	0.658
MOD_Plk_2-3	381	387	PF00069	0.455
MOD_Plk_4	171	177	PF00069	0.601
MOD_Plk_4	206	212	PF00069	0.482
MOD_Plk_4	456	462	PF00069	0.384
MOD_Plk_4	5	11	PF00069	0.603
MOD_Plk_4	566	572	PF00069	0.238
MOD_Plk_4	687	693	PF00069	0.560
MOD_Plk_4	727	733	PF00069	0.600
MOD_Plk_4	85	91	PF00069	0.532
MOD_ProDKin_1	10	16	PF00069	0.718
MOD_ProDKin_1	1038	1044	PF00069	0.788
MOD_ProDKin_1	1071	1077	PF00069	0.695
MOD_ProDKin_1	22	28	PF00069	0.678
MOD_ProDKin_1	41	47	PF00069	0.550
MOD_ProDKin_1	61	67	PF00069	0.475
MOD_ProDKin_1	673	679	PF00069	0.563
MOD_ProDKin_1	966	972	PF00069	0.654
MOD_ProDKin_1	97	103	PF00069	0.575
MOD_SUMO_rev_2	348	357	PF00179	0.436
TRG_DiLeu_BaEn_2	445	451	PF01217	0.367
TRG_DiLeu_BaLyEn_6	346	351	PF01217	0.455
TRG_ENDOCYTIC_2	289	292	PF00928	0.469
TRG_ENDOCYTIC_2	335	338	PF00928	0.486
TRG_ENDOCYTIC_2	343	346	PF00928	0.401
TRG_ENDOCYTIC_2	548	551	PF00928	0.244
TRG_ENDOCYTIC_2	738	741	PF00928	0.482
TRG_ENDOCYTIC_2	776	779	PF00928	0.455
TRG_ENDOCYTIC_2	912	915	PF00928	0.452
TRG_ER_diArg_1	1002	1005	PF00400	0.747
TRG_ER_diArg_1	108	111	PF00400	0.597
TRG_ER_diArg_1	118	120	PF00400	0.706
TRG_ER_diArg_1	199	202	PF00400	0.571
TRG_ER_diArg_1	227	229	PF00400	0.510
TRG_ER_diArg_1	472	475	PF00400	0.520
TRG_ER_diArg_1	510	512	PF00400	0.401
TRG_ER_diArg_1	521	524	PF00400	0.453
TRG_ER_diArg_1	959	961	PF00400	0.542
TRG_NES_CRM1_1	307	317	PF08389	0.515
TRG_NES_CRM1_1	398	412	PF08389	0.620
TRG_NES_CRM1_1	456	467	PF08389	0.310
TRG_NES_CRM1_1	857	871	PF08389	0.452
TRG_NLS_Bipartite_1	111	128	PF00514	0.714
TRG_NLS_MonoExtC_3	123	128	PF00514	0.743
TRG_NLS_MonoExtC_3	184	190	PF00514	0.619
TRG_NLS_MonoExtC_3	96	101	PF00514	0.679
TRG_Pf-PMV_PEXEL_1	1082	1086	PF00026	0.405
TRG_Pf-PMV_PEXEL_1	112	117	PF00026	0.357
TRG_Pf-PMV_PEXEL_1	579	583	PF00026	0.314
TRG_Pf-PMV_PEXEL_1	683	688	PF00026	0.407

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8F0	Leptomonas seymouri	56%	89%
A0A0S4IQT3	Bodo saltans	38%	100%
A0A1X0NRE3	Trypanosomatidae	43%	100%
A0A3R7P0G4	Trypanosoma rangeli	43%	100%
A0A3S5H7J4	Leishmania donovani	92%	100%
A4HGL3	Leishmania braziliensis	79%	100%
A4I3N9	Leishmania infantum	91%	88%
D0A8C5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
E9AZY0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
V5BAP9	Trypanosoma cruzi	43%	100%