Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q846_LEIMA

TriTrypDb:

LmjF.28.2190 , LMJLV39_280030000 , LMJSD75_280029600

Length:

912

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q846

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q846

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	115	117	PF00675	0.618
CLV_NRD_NRD_1	269	271	PF00675	0.728
CLV_NRD_NRD_1	352	354	PF00675	0.778
CLV_NRD_NRD_1	495	497	PF00675	0.780
CLV_NRD_NRD_1	501	503	PF00675	0.675
CLV_NRD_NRD_1	686	688	PF00675	0.689
CLV_NRD_NRD_1	787	789	PF00675	0.625
CLV_NRD_NRD_1	811	813	PF00675	0.671
CLV_NRD_NRD_1	875	877	PF00675	0.709
CLV_PCSK_KEX2_1	115	117	PF00082	0.616

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IQR9	Leishmania donovani	92%	100%
A4HGS3	Leishmania braziliensis	68%	100%
A4I3U8	Leishmania infantum	91%	100%
E9B040	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%

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