Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q832_LEIMA

TriTrypDb:

LmjF.28.2320 , LMJLV39_280031300 , LMJSD75_280030900

Length:

904

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q832

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q832

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	434	438	PF00656	0.654
CLV_C14_Caspase3-7	656	660	PF00656	0.685
CLV_C14_Caspase3-7	863	867	PF00656	0.586
CLV_NRD_NRD_1	106	108	PF00675	0.820
CLV_NRD_NRD_1	113	115	PF00675	0.755
CLV_NRD_NRD_1	169	171	PF00675	0.630
CLV_NRD_NRD_1	338	340	PF00675	0.675
CLV_NRD_NRD_1	36	38	PF00675	0.626
CLV_NRD_NRD_1	380	382	PF00675	0.625
CLV_NRD_NRD_1	414	416	PF00675	0.708
CLV_NRD_NRD_1	420	422	PF00675	0.741
CLV_NRD_NRD_1	446	448	PF00675	0.695
CLV_NRD_NRD_1	532	534	PF00675	0.602
CLV_NRD_NRD_1	608	610	PF00675	0.565
CLV_NRD_NRD_1	768	770	PF00675	0.646
CLV_NRD_NRD_1	79	81	PF00675	0.706
CLV_NRD_NRD_1	8	10	PF00675	0.607
CLV_PCSK_FUR_1	146	150	PF00082	0.607
CLV_PCSK_KEX2_1	106	108	PF00082	0.820
CLV_PCSK_KEX2_1	113	115	PF00082	0.740
CLV_PCSK_KEX2_1	148	150	PF00082	0.558
CLV_PCSK_KEX2_1	169	171	PF00082	0.630
CLV_PCSK_KEX2_1	338	340	PF00082	0.675
CLV_PCSK_KEX2_1	35	37	PF00082	0.640
CLV_PCSK_KEX2_1	380	382	PF00082	0.625
CLV_PCSK_KEX2_1	414	416	PF00082	0.708
CLV_PCSK_KEX2_1	420	422	PF00082	0.741
CLV_PCSK_KEX2_1	445	447	PF00082	0.666
CLV_PCSK_KEX2_1	532	534	PF00082	0.602
CLV_PCSK_KEX2_1	608	610	PF00082	0.565
CLV_PCSK_KEX2_1	679	681	PF00082	0.632
CLV_PCSK_KEX2_1	79	81	PF00082	0.704
CLV_PCSK_KEX2_1	8	10	PF00082	0.612
CLV_PCSK_KEX2_1	827	829	PF00082	0.580
CLV_PCSK_PC1ET2_1	148	150	PF00082	0.561
CLV_PCSK_PC1ET2_1	679	681	PF00082	0.632
CLV_PCSK_PC1ET2_1	827	829	PF00082	0.580
CLV_PCSK_PC7_1	442	448	PF00082	0.548
CLV_PCSK_SKI1_1	114	118	PF00082	0.698
CLV_PCSK_SKI1_1	284	288	PF00082	0.620
CLV_PCSK_SKI1_1	344	348	PF00082	0.535
CLV_PCSK_SKI1_1	446	450	PF00082	0.731
CLV_PCSK_SKI1_1	452	456	PF00082	0.684
CLV_PCSK_SKI1_1	497	501	PF00082	0.570
CLV_PCSK_SKI1_1	504	508	PF00082	0.585
CLV_PCSK_SKI1_1	734	738	PF00082	0.636
DEG_APCC_DBOX_1	283	291	PF00400	0.508
DEG_SCF_FBW7_1	318	325	PF00400	0.657
DEG_SCF_FBW7_1	653	658	PF00400	0.546
DEG_SCF_TRCP1_1	529	535	PF00400	0.636
DEG_SPOP_SBC_1	322	326	PF00917	0.633
DEG_SPOP_SBC_1	40	44	PF00917	0.593
DEG_SPOP_SBC_1	877	881	PF00917	0.537
DOC_ANK_TNKS_1	337	344	PF00023	0.517
DOC_CKS1_1	183	188	PF01111	0.591
DOC_CKS1_1	319	324	PF01111	0.656
DOC_CKS1_1	819	824	PF01111	0.617
DOC_CYCLIN_yCln2_LP_2	246	249	PF00134	0.547
DOC_CYCLIN_yCln2_LP_2	557	563	PF00134	0.631
DOC_CYCLIN_yCln2_LP_2	571	577	PF00134	0.581
DOC_CYCLIN_yCln2_LP_2	898	904	PF00134	0.581
DOC_MAPK_gen_1	388	396	PF00069	0.548
DOC_MAPK_MEF2A_6	724	731	PF00069	0.633
DOC_PP2B_LxvP_1	246	249	PF13499	0.573
DOC_PP2B_LxvP_1	571	574	PF13499	0.681
DOC_PP2B_LxvP_1	717	720	PF13499	0.625
DOC_PP2B_LxvP_1	898	901	PF13499	0.578
DOC_PP4_FxxP_1	838	841	PF00568	0.569
DOC_USP7_MATH_1	10	14	PF00917	0.599
DOC_USP7_MATH_1	118	122	PF00917	0.714
DOC_USP7_MATH_1	128	132	PF00917	0.513
DOC_USP7_MATH_1	191	195	PF00917	0.662
DOC_USP7_MATH_1	24	28	PF00917	0.607
DOC_USP7_MATH_1	322	326	PF00917	0.741
DOC_USP7_MATH_1	373	377	PF00917	0.678
DOC_USP7_MATH_1	40	44	PF00917	0.630
DOC_USP7_MATH_1	424	428	PF00917	0.637
DOC_USP7_MATH_1	477	481	PF00917	0.657
DOC_USP7_MATH_1	515	519	PF00917	0.544
DOC_USP7_MATH_1	586	590	PF00917	0.627
DOC_USP7_MATH_1	648	652	PF00917	0.647
DOC_USP7_MATH_1	655	659	PF00917	0.579
DOC_USP7_MATH_1	665	669	PF00917	0.485
DOC_USP7_MATH_1	67	71	PF00917	0.583
DOC_USP7_MATH_1	775	779	PF00917	0.599
DOC_USP7_MATH_1	782	786	PF00917	0.588
DOC_USP7_MATH_1	817	821	PF00917	0.657
DOC_USP7_MATH_1	885	889	PF00917	0.611
DOC_USP7_MATH_1	891	895	PF00917	0.531
DOC_WW_Pin1_4	163	168	PF00397	0.612
DOC_WW_Pin1_4	182	187	PF00397	0.629
DOC_WW_Pin1_4	192	197	PF00397	0.592
DOC_WW_Pin1_4	223	228	PF00397	0.677
DOC_WW_Pin1_4	257	262	PF00397	0.550
DOC_WW_Pin1_4	311	316	PF00397	0.787
DOC_WW_Pin1_4	318	323	PF00397	0.668
DOC_WW_Pin1_4	327	332	PF00397	0.565
DOC_WW_Pin1_4	366	371	PF00397	0.605
DOC_WW_Pin1_4	400	405	PF00397	0.744
DOC_WW_Pin1_4	420	425	PF00397	0.500
DOC_WW_Pin1_4	483	488	PF00397	0.689
DOC_WW_Pin1_4	598	603	PF00397	0.602
DOC_WW_Pin1_4	651	656	PF00397	0.555
DOC_WW_Pin1_4	681	686	PF00397	0.651
DOC_WW_Pin1_4	706	711	PF00397	0.675
DOC_WW_Pin1_4	818	823	PF00397	0.637
DOC_WW_Pin1_4	99	104	PF00397	0.631
LIG_14-3-3_CanoR_1	153	158	PF00244	0.650
LIG_14-3-3_CanoR_1	170	180	PF00244	0.543
LIG_14-3-3_CanoR_1	201	207	PF00244	0.647
LIG_14-3-3_CanoR_1	3	7	PF00244	0.638
LIG_14-3-3_CanoR_1	559	564	PF00244	0.711
LIG_14-3-3_CanoR_1	624	629	PF00244	0.619
LIG_14-3-3_CanoR_1	666	673	PF00244	0.590
LIG_14-3-3_CanoR_1	701	706	PF00244	0.650
LIG_14-3-3_CanoR_1	734	739	PF00244	0.676
LIG_14-3-3_CanoR_1	8	18	PF00244	0.584
LIG_BIR_II_1	1	5	PF00653	0.678
LIG_BIR_III_2	779	783	PF00653	0.555
LIG_BRCT_BRCA1_1	153	157	PF00533	0.518
LIG_BRCT_BRCA1_1	344	348	PF00533	0.556
LIG_BRCT_BRCA1_1	784	788	PF00533	0.539
LIG_BRCT_BRCA1_1	855	859	PF00533	0.617
LIG_DLG_GKlike_1	624	631	PF00625	0.632
LIG_eIF4E_1	293	299	PF01652	0.553
LIG_EVH1_2	196	200	PF00568	0.537
LIG_FHA_1	239	245	PF00498	0.711
LIG_FHA_1	322	328	PF00498	0.645
LIG_FHA_1	484	490	PF00498	0.627
LIG_FHA_1	712	718	PF00498	0.648
LIG_FHA_1	754	760	PF00498	0.630
LIG_FHA_1	819	825	PF00498	0.645
LIG_FHA_1	893	899	PF00498	0.500
LIG_FHA_2	421	427	PF00498	0.619
LIG_FHA_2	579	585	PF00498	0.645
LIG_FHA_2	652	658	PF00498	0.778
LIG_LIR_Apic_2	57	62	PF02991	0.522
LIG_LIR_Apic_2	73	77	PF02991	0.579
LIG_LIR_Gen_1	345	355	PF02991	0.631
LIG_LIR_Gen_1	397	407	PF02991	0.546
LIG_LIR_Gen_1	791	798	PF02991	0.531
LIG_LIR_Nem_3	345	351	PF02991	0.668
LIG_LIR_Nem_3	397	402	PF02991	0.550
LIG_LIR_Nem_3	791	796	PF02991	0.531
LIG_Pex14_1	789	793	PF04695	0.618
LIG_Pex14_2	157	161	PF04695	0.532
LIG_SH2_CRK	302	306	PF00017	0.545
LIG_SH2_CRK	59	63	PF00017	0.520
LIG_SH2_CRK	74	78	PF00017	0.580
LIG_SH2_GRB2like	84	87	PF00017	0.628
LIG_SH2_PTP2	793	796	PF00017	0.530
LIG_SH2_SRC	84	87	PF00017	0.591
LIG_SH2_STAT3	141	144	PF00017	0.602
LIG_SH2_STAT3	293	296	PF00017	0.548
LIG_SH2_STAT3	611	614	PF00017	0.613
LIG_SH2_STAT5	417	420	PF00017	0.640
LIG_SH2_STAT5	47	50	PF00017	0.632
LIG_SH2_STAT5	611	614	PF00017	0.569
LIG_SH2_STAT5	793	796	PF00017	0.530
LIG_SH3_1	106	112	PF00018	0.647
LIG_SH3_2	108	113	PF14604	0.688
LIG_SH3_2	196	201	PF14604	0.611
LIG_SH3_3	105	111	PF00018	0.684
LIG_SH3_3	180	186	PF00018	0.652
LIG_SH3_3	193	199	PF00018	0.555
LIG_SH3_3	242	248	PF00018	0.582
LIG_SH3_3	272	278	PF00018	0.444
LIG_SH3_3	316	322	PF00018	0.682
LIG_SH3_3	399	405	PF00018	0.665
LIG_SH3_3	410	416	PF00018	0.705
LIG_SH3_3	450	456	PF00018	0.675
LIG_SH3_3	587	593	PF00018	0.637
LIG_SH3_3	717	723	PF00018	0.711
LIG_SH3_3	726	732	PF00018	0.535
LIG_SH3_3	816	822	PF00018	0.643
LIG_SH3_CIN85_PxpxPR_1	108	113	PF14604	0.688
LIG_SH3_CIN85_PxpxPR_1	315	320	PF14604	0.634
LIG_SUMO_SIM_par_1	574	579	PF11976	0.566
LIG_TRAF2_1	552	555	PF00917	0.576
LIG_TRAF2_2	841	846	PF00917	0.584
LIG_UBA3_1	575	583	PF00899	0.563
LIG_WW_2	196	199	PF00397	0.595
LIG_WW_3	110	114	PF00397	0.692
LIG_WW_3	32	36	PF00397	0.632
MOD_CDC14_SPxK_1	330	333	PF00782	0.660
MOD_CDK_SPxK_1	163	169	PF00069	0.583
MOD_CDK_SPxK_1	327	333	PF00069	0.659
MOD_CDK_SPxxK_3	163	170	PF00069	0.639
MOD_CDK_SPxxK_3	99	106	PF00069	0.657
MOD_CK1_1	172	178	PF00069	0.800
MOD_CK1_1	2	8	PF00069	0.677
MOD_CK1_1	226	232	PF00069	0.639
MOD_CK1_1	323	329	PF00069	0.645
MOD_CK1_1	369	375	PF00069	0.573
MOD_CK1_1	39	45	PF00069	0.659
MOD_CK1_1	403	409	PF00069	0.621
MOD_CK1_1	478	484	PF00069	0.813
MOD_CK1_1	626	632	PF00069	0.703
MOD_CK1_1	651	657	PF00069	0.813
MOD_CK1_1	684	690	PF00069	0.789
MOD_CK1_1	70	76	PF00069	0.612
MOD_CK1_1	704	710	PF00069	0.494
MOD_CK1_1	847	853	PF00069	0.625
MOD_CK2_1	559	565	PF00069	0.633
MOD_CK2_1	578	584	PF00069	0.510
MOD_CK2_1	651	657	PF00069	0.761
MOD_CK2_1	737	743	PF00069	0.716
MOD_CK2_1	891	897	PF00069	0.630
MOD_Cter_Amidation	530	533	PF01082	0.571
MOD_Cter_Amidation	677	680	PF01082	0.632
MOD_Cter_Amidation	767	770	PF01082	0.580
MOD_Cter_Amidation	825	828	PF01082	0.591
MOD_GlcNHglycan	12	15	PF01048	0.663
MOD_GlcNHglycan	120	123	PF01048	0.669
MOD_GlcNHglycan	130	133	PF01048	0.538
MOD_GlcNHglycan	175	178	PF01048	0.750
MOD_GlcNHglycan	180	183	PF01048	0.799
MOD_GlcNHglycan	223	226	PF01048	0.682
MOD_GlcNHglycan	344	347	PF01048	0.505
MOD_GlcNHglycan	38	41	PF01048	0.688
MOD_GlcNHglycan	426	429	PF01048	0.744
MOD_GlcNHglycan	43	46	PF01048	0.620
MOD_GlcNHglycan	434	437	PF01048	0.648
MOD_GlcNHglycan	476	480	PF01048	0.706
MOD_GlcNHglycan	517	520	PF01048	0.583
MOD_GlcNHglycan	529	532	PF01048	0.769
MOD_GlcNHglycan	631	634	PF01048	0.738
MOD_GlcNHglycan	646	649	PF01048	0.529
MOD_GlcNHglycan	668	671	PF01048	0.646
MOD_GlcNHglycan	676	679	PF01048	0.654
MOD_GlcNHglycan	69	72	PF01048	0.591
MOD_GlcNHglycan	691	695	PF01048	0.557
MOD_GlcNHglycan	739	742	PF01048	0.600
MOD_GlcNHglycan	756	759	PF01048	0.643
MOD_GlcNHglycan	784	787	PF01048	0.562
MOD_GlcNHglycan	814	817	PF01048	0.770
MOD_GlcNHglycan	838	841	PF01048	0.538
MOD_GSK3_1	114	121	PF00069	0.763
MOD_GSK3_1	169	176	PF00069	0.687
MOD_GSK3_1	178	185	PF00069	0.617
MOD_GSK3_1	318	325	PF00069	0.641
MOD_GSK3_1	36	43	PF00069	0.605
MOD_GSK3_1	369	376	PF00069	0.608
MOD_GSK3_1	420	427	PF00069	0.682
MOD_GSK3_1	478	485	PF00069	0.789
MOD_GSK3_1	644	651	PF00069	0.670
MOD_GSK3_1	66	73	PF00069	0.627
MOD_GSK3_1	686	693	PF00069	0.841
MOD_GSK3_1	700	707	PF00069	0.645
MOD_GSK3_1	730	737	PF00069	0.637
MOD_GSK3_1	749	756	PF00069	0.712
MOD_GSK3_1	849	856	PF00069	0.725
MOD_GSK3_1	873	880	PF00069	0.636
MOD_LATS_1	767	773	PF00433	0.643
MOD_N-GLC_1	128	133	PF02516	0.563
MOD_N-GLC_1	666	671	PF02516	0.543
MOD_N-GLC_1	891	896	PF02516	0.639
MOD_NEK2_1	161	166	PF00069	0.725
MOD_NEK2_1	200	205	PF00069	0.686
MOD_NEK2_1	394	399	PF00069	0.625
MOD_NEK2_1	495	500	PF00069	0.604
MOD_NEK2_1	55	60	PF00069	0.535
MOD_NEK2_1	576	581	PF00069	0.697
MOD_NEK2_1	673	678	PF00069	0.614
MOD_NEK2_1	690	695	PF00069	0.620
MOD_NEK2_1	700	705	PF00069	0.692
MOD_NEK2_1	844	849	PF00069	0.608
MOD_PIKK_1	140	146	PF00454	0.624
MOD_PIKK_1	151	157	PF00454	0.611
MOD_PIKK_1	259	265	PF00454	0.599
MOD_PIKK_1	47	53	PF00454	0.625
MOD_PIKK_1	478	484	PF00454	0.661
MOD_PK_1	532	538	PF00069	0.561
MOD_PK_1	701	707	PF00069	0.582
MOD_PKA_1	169	175	PF00069	0.632
MOD_PKA_1	36	42	PF00069	0.608
MOD_PKA_1	532	538	PF00069	0.590
MOD_PKA_1	769	775	PF00069	0.642
MOD_PKA_2	169	175	PF00069	0.654
MOD_PKA_2	2	8	PF00069	0.677
MOD_PKA_2	200	206	PF00069	0.650
MOD_PKA_2	36	42	PF00069	0.608
MOD_PKA_2	532	538	PF00069	0.652
MOD_PKA_2	55	61	PF00069	0.608
MOD_PKA_2	623	629	PF00069	0.639
MOD_PKA_2	665	671	PF00069	0.541
MOD_PKA_2	700	706	PF00069	0.650
MOD_PKB_1	622	630	PF00069	0.647
MOD_Plk_1	250	256	PF00069	0.508
MOD_Plk_1	586	592	PF00069	0.652
MOD_Plk_1	844	850	PF00069	0.654
MOD_Plk_4	153	159	PF00069	0.533
MOD_Plk_4	231	237	PF00069	0.670
MOD_Plk_4	239	245	PF00069	0.581
MOD_Plk_4	50	56	PF00069	0.609
MOD_Plk_4	844	850	PF00069	0.611
MOD_ProDKin_1	163	169	PF00069	0.615
MOD_ProDKin_1	182	188	PF00069	0.631
MOD_ProDKin_1	192	198	PF00069	0.594
MOD_ProDKin_1	223	229	PF00069	0.677
MOD_ProDKin_1	257	263	PF00069	0.540
MOD_ProDKin_1	311	317	PF00069	0.790
MOD_ProDKin_1	318	324	PF00069	0.667
MOD_ProDKin_1	327	333	PF00069	0.566
MOD_ProDKin_1	366	372	PF00069	0.607
MOD_ProDKin_1	400	406	PF00069	0.744
MOD_ProDKin_1	420	426	PF00069	0.500
MOD_ProDKin_1	483	489	PF00069	0.688
MOD_ProDKin_1	598	604	PF00069	0.599
MOD_ProDKin_1	651	657	PF00069	0.558
MOD_ProDKin_1	681	687	PF00069	0.655
MOD_ProDKin_1	706	712	PF00069	0.671
MOD_ProDKin_1	818	824	PF00069	0.640
MOD_ProDKin_1	99	105	PF00069	0.630
TRG_DiLeu_BaEn_1	294	299	PF01217	0.491
TRG_DiLeu_BaEn_1	639	644	PF01217	0.668
TRG_DiLeu_BaEn_2	742	748	PF01217	0.618
TRG_DiLeu_BaLyEn_6	269	274	PF01217	0.566
TRG_DiLeu_BaLyEn_6	484	489	PF01217	0.629
TRG_DiLeu_BaLyEn_6	571	576	PF01217	0.644
TRG_DiLeu_LyEn_5	294	299	PF01217	0.491
TRG_ENDOCYTIC_2	302	305	PF00928	0.540
TRG_ENDOCYTIC_2	793	796	PF00928	0.530
TRG_ER_diArg_1	106	108	PF00400	0.829
TRG_ER_diArg_1	112	114	PF00400	0.758
TRG_ER_diArg_1	168	170	PF00400	0.664
TRG_ER_diArg_1	34	37	PF00400	0.632
TRG_ER_diArg_1	413	415	PF00400	0.699
TRG_ER_diArg_1	444	447	PF00400	0.734
TRG_ER_diArg_1	456	459	PF00400	0.610
TRG_ER_diArg_1	622	625	PF00400	0.704
TRG_ER_diArg_1	79	81	PF00400	0.728
TRG_ER_diArg_1	8	10	PF00400	0.621
TRG_Pf-PMV_PEXEL_1	272	276	PF00026	0.579

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4B6	Leptomonas seymouri	27%	100%
A0A3Q8IE27	Leishmania donovani	89%	100%
A4HGT6	Leishmania braziliensis	59%	97%
A4I3W3	Leishmania infantum	89%	100%
E9B053	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%