DUF676 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:

Gene product:

Putative serine esterase (DUF676), putative

Species:

Leishmania major

UniProt:

Q4Q819_LEIMA

TriTrypDb:

LmjF.28.2445 , LMJLV39_280032600 , LMJSD75_280032200

Length:

292

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q819

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q819

Function

Biological processes
Term	Name	Level	Count
GO:0006629	lipid metabolic process	3	2
GO:0008152	metabolic process	1	2
GO:0009987	cellular process	1	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044255	cellular lipid metabolic process	3	2
GO:0071704	organic substance metabolic process	2	2

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	209	215	PF00089	0.741
CLV_NRD_NRD_1	184	186	PF00675	0.549
CLV_NRD_NRD_1	211	213	PF00675	0.756
CLV_NRD_NRD_1	283	285	PF00675	0.800
CLV_NRD_NRD_1	4	6	PF00675	0.739
CLV_PCSK_FUR_1	181	185	PF00082	0.549
CLV_PCSK_KEX2_1	139	141	PF00082	0.549
CLV_PCSK_KEX2_1	183	185	PF00082	0.549
CLV_PCSK_KEX2_1	211	213	PF00082	0.756
CLV_PCSK_KEX2_1	24	26	PF00082	0.387
CLV_PCSK_KEX2_1	4	6	PF00082	0.736
CLV_PCSK_PC1ET2_1	139	141	PF00082	0.549
CLV_PCSK_PC1ET2_1	183	185	PF00082	0.549
CLV_PCSK_PC1ET2_1	24	26	PF00082	0.737
CLV_PCSK_SKI1_1	184	188	PF00082	0.549
CLV_PCSK_SKI1_1	21	25	PF00082	0.712
CLV_PCSK_SKI1_1	33	37	PF00082	0.528
CLV_PCSK_SKI1_1	39	43	PF00082	0.439
CLV_PCSK_SKI1_1	95	99	PF00082	0.549
DEG_APCC_DBOX_1	183	191	PF00400	0.549
DEG_APCC_DBOX_1	94	102	PF00400	0.549
DOC_CKS1_1	126	131	PF01111	0.549
DOC_CYCLIN_RxL_1	1	12	PF00134	0.766
DOC_MAPK_gen_1	181	190	PF00069	0.549
DOC_MAPK_MEF2A_6	162	170	PF00069	0.549
DOC_MAPK_MEF2A_6	181	190	PF00069	0.217
DOC_PP1_RVXF_1	77	83	PF00149	0.622
DOC_USP7_MATH_1	216	220	PF00917	0.771
DOC_USP7_MATH_1	41	45	PF00917	0.720
DOC_USP7_MATH_1	49	53	PF00917	0.585
DOC_WW_Pin1_4	125	130	PF00397	0.549
LIG_14-3-3_CanoR_1	10	14	PF00244	0.739
LIG_14-3-3_CanoR_1	140	144	PF00244	0.549
LIG_14-3-3_CanoR_1	162	166	PF00244	0.549
LIG_14-3-3_CanoR_1	260	269	PF00244	0.786
LIG_14-3-3_CanoR_1	278	284	PF00244	0.472
LIG_14-3-3_CanoR_1	33	43	PF00244	0.743
LIG_14-3-3_CanoR_1	71	80	PF00244	0.701
LIG_14-3-3_CterR_2	289	292	PF00244	0.795
LIG_Actin_WH2_2	82	97	PF00022	0.549
LIG_BRCT_BRCA1_1	199	203	PF00533	0.693
LIG_deltaCOP1_diTrp_1	117	123	PF00928	0.549
LIG_EH1_1	86	94	PF00400	0.549
LIG_FHA_1	126	132	PF00498	0.549
LIG_FHA_1	139	145	PF00498	0.322
LIG_FHA_1	18	24	PF00498	0.694
LIG_FHA_1	204	210	PF00498	0.727
LIG_FHA_1	71	77	PF00498	0.732
LIG_FHA_2	102	108	PF00498	0.549
LIG_FHA_2	218	224	PF00498	0.772
LIG_LIR_Gen_1	106	115	PF02991	0.549
LIG_LIR_Gen_1	117	127	PF02991	0.357
LIG_LIR_Gen_1	12	19	PF02991	0.715
LIG_LIR_Nem_3	106	112	PF02991	0.549
LIG_LIR_Nem_3	117	123	PF02991	0.357
LIG_LIR_Nem_3	12	16	PF02991	0.730
LIG_LIR_Nem_3	265	271	PF02991	0.790
LIG_MAD2	208	216	PF02301	0.749
LIG_SH2_CRK	13	17	PF00017	0.726
LIG_SH2_SRC	272	275	PF00017	0.785
LIG_SH2_STAP1	13	17	PF00017	0.726
LIG_SH2_STAP1	199	203	PF00017	0.693
LIG_SH2_STAT5	272	275	PF00017	0.785
LIG_SH3_3	210	216	PF00018	0.752
LIG_SH3_3	263	269	PF00018	0.789
LIG_TRAF2_1	104	107	PF00917	0.549
LIG_TRAF2_1	220	223	PF00917	0.769
MOD_CK1_1	12	18	PF00069	0.652
MOD_CK1_1	138	144	PF00069	0.549
MOD_CK1_1	261	267	PF00069	0.785
MOD_CK1_1	279	285	PF00069	0.473
MOD_CK1_1	37	43	PF00069	0.743
MOD_CK1_1	51	57	PF00069	0.456
MOD_CK2_1	101	107	PF00069	0.549
MOD_CK2_1	216	222	PF00069	0.771
MOD_Cter_Amidation	2	5	PF01082	0.804
MOD_GlcNHglycan	237	240	PF01048	0.789
MOD_GlcNHglycan	289	292	PF01048	0.795
MOD_GlcNHglycan	36	39	PF01048	0.743
MOD_GlcNHglycan	51	54	PF01048	0.449
MOD_GlcNHglycan	82	85	PF01048	0.549
MOD_GSK3_1	135	142	PF00069	0.549
MOD_GSK3_1	195	202	PF00069	0.549
MOD_GSK3_1	258	265	PF00069	0.780
MOD_GSK3_1	272	279	PF00069	0.538
MOD_GSK3_1	33	40	PF00069	0.746
MOD_NEK2_1	160	165	PF00069	0.549
MOD_NEK2_1	17	22	PF00069	0.691
MOD_NEK2_1	197	202	PF00069	0.549
MOD_NEK2_1	203	208	PF00069	0.623
MOD_NEK2_1	243	248	PF00069	0.788
MOD_NEK2_1	80	85	PF00069	0.549
MOD_NEK2_2	262	267	PF00069	0.787
MOD_OFUCOSY	255	262	PF10250	0.760
MOD_OFUCOSY	276	281	PF10250	0.780
MOD_PKA_1	139	145	PF00069	0.549
MOD_PKA_2	139	145	PF00069	0.549
MOD_PKA_2	161	167	PF00069	0.549
MOD_PKA_2	277	283	PF00069	0.783
MOD_PKA_2	70	76	PF00069	0.746
MOD_PKA_2	9	15	PF00069	0.673
MOD_Plk_4	12	18	PF00069	0.719
MOD_Plk_4	139	145	PF00069	0.549
MOD_Plk_4	161	167	PF00069	0.549
MOD_Plk_4	199	205	PF00069	0.702
MOD_Plk_4	51	57	PF00069	0.701
MOD_ProDKin_1	125	131	PF00069	0.549
MOD_SUMO_for_1	231	234	PF00179	0.789
TRG_ENDOCYTIC_2	109	112	PF00928	0.549
TRG_ENDOCYTIC_2	13	16	PF00928	0.728
TRG_ER_diArg_1	184	186	PF00400	0.549
TRG_ER_diArg_1	210	212	PF00400	0.740
TRG_ER_diArg_1	4	6	PF00400	0.736
TRG_NLS_MonoExtN_4	181	187	PF00514	0.549