ADP-ribosylglycohydrolase family protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ADP-ribosylglycohydrolase, putative

Species:

Leishmania major

UniProt:

Q4Q802_LEIMA

TriTrypDb:

LmjF.28.2590 , LMJLV39_280034400 , LMJSD75_280033900

Length:

417

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0031974	membrane-enclosed lumen	2	2
GO:0031981	nuclear lumen	5	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0043233	organelle lumen	3	2
GO:0070013	intracellular organelle lumen	4	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	2

Previous1Next

Expansion

Sequence features

Q4Q802

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q802

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0016787	hydrolase activity	2	1

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	220	224	PF00656	0.498
CLV_C14_Caspase3-7	260	264	PF00656	0.512
CLV_C14_Caspase3-7	332	336	PF00656	0.482
CLV_PCSK_SKI1_1	369	373	PF00082	0.319
CLV_PCSK_SKI1_1	93	97	PF00082	0.516
CLV_Separin_Metazoa	136	140	PF03568	0.459
DEG_APCC_DBOX_1	298	306	PF00400	0.687
DEG_SPOP_SBC_1	111	115	PF00917	0.648
DOC_CKS1_1	185	190	PF01111	0.449
DOC_CYCLIN_yCln2_LP_2	185	191	PF00134	0.376

Previous1 2 3 4 5…14Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBW3	Leptomonas seymouri	59%	97%
A0A0S4IN38	Bodo saltans	33%	100%
A0A1X0NQK8	Trypanosomatidae	41%	100%
A0A3Q8IF26	Leishmania donovani	92%	100%
A0A3R7KDQ9	Trypanosoma rangeli	45%	100%
A4HGW3	Leishmania braziliensis	81%	100%
A4I3Z3	Leishmania infantum	92%	100%
D0A963	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
E9B083	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
V5BC55	Trypanosoma cruzi	44%	100%

Previous1Next