Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q7X5_LEIMA

TriTrypDb:

LmjF.28.2870 , LMJLV39_280037200 , LMJSD75_280036800

Length:

250

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q7X5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q7X5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	57	61	PF00656	0.602
CLV_NRD_NRD_1	122	124	PF00675	0.661
CLV_NRD_NRD_1	125	127	PF00675	0.613
CLV_NRD_NRD_1	21	23	PF00675	0.514
CLV_NRD_NRD_1	74	76	PF00675	0.611
CLV_NRD_NRD_1	87	89	PF00675	0.500
CLV_PCSK_KEX2_1	122	124	PF00082	0.661
CLV_PCSK_KEX2_1	21	23	PF00082	0.539
CLV_PCSK_KEX2_1	74	76	PF00082	0.611
CLV_PCSK_KEX2_1	87	89	PF00082	0.500
CLV_PCSK_SKI1_1	208	212	PF00082	0.423
CLV_PCSK_SKI1_1	225	229	PF00082	0.362
CLV_PCSK_SKI1_1	74	78	PF00082	0.644
DEG_APCC_DBOX_1	74	82	PF00400	0.609
DOC_MAPK_gen_1	21	29	PF00069	0.496
DOC_MAPK_gen_1	87	95	PF00069	0.546
DOC_PP1_RVXF_1	238	245	PF00149	0.467
DOC_PP1_RVXF_1	28	35	PF00149	0.404
DOC_USP7_MATH_1	198	202	PF00917	0.600
DOC_USP7_MATH_1	67	71	PF00917	0.523
DOC_WW_Pin1_4	155	160	PF00397	0.647
DOC_WW_Pin1_4	161	166	PF00397	0.653
LIG_14-3-3_CanoR_1	24	28	PF00244	0.554
LIG_BIR_II_1	1	5	PF00653	0.534
LIG_BRCT_BRCA1_1	200	204	PF00533	0.462
LIG_BRCT_BRCA1_1	240	244	PF00533	0.601
LIG_Clathr_ClatBox_1	147	151	PF01394	0.528
LIG_FHA_1	106	112	PF00498	0.537
LIG_FHA_1	181	187	PF00498	0.617
LIG_FHA_1	24	30	PF00498	0.564
LIG_FHA_2	95	101	PF00498	0.707
LIG_LIR_Nem_3	100	106	PF02991	0.630
LIG_LIR_Nem_3	201	207	PF02991	0.470
LIG_LIR_Nem_3	241	247	PF02991	0.467
LIG_REV1ctd_RIR_1	202	212	PF16727	0.476
LIG_SH2_NCK_1	195	199	PF00017	0.457
LIG_SH2_SRC	195	198	PF00017	0.446
LIG_SH3_2	121	126	PF14604	0.578
LIG_SH3_2	17	22	PF14604	0.567
LIG_SH3_3	118	124	PF00018	0.618
LIG_SH3_3	14	20	PF00018	0.564
LIG_SUMO_SIM_anti_2	143	149	PF11976	0.483
LIG_SUMO_SIM_par_1	25	31	PF11976	0.524
MOD_CK1_1	155	161	PF00069	0.622
MOD_CK1_1	164	170	PF00069	0.566
MOD_CK1_1	94	100	PF00069	0.601
MOD_CK2_1	174	180	PF00069	0.562
MOD_CK2_1	41	47	PF00069	0.551
MOD_GlcNHglycan	154	157	PF01048	0.612
MOD_GlcNHglycan	213	216	PF01048	0.443
MOD_GlcNHglycan	47	50	PF01048	0.580
MOD_GlcNHglycan	69	72	PF01048	0.549
MOD_GSK3_1	151	158	PF00069	0.682
MOD_GSK3_1	170	177	PF00069	0.461
MOD_GSK3_1	41	48	PF00069	0.530
MOD_GSK3_1	50	57	PF00069	0.499
MOD_GSK3_1	89	96	PF00069	0.638
MOD_N-GLC_1	60	65	PF02516	0.572
MOD_NEK2_1	141	146	PF00069	0.473
MOD_NEK2_1	152	157	PF00069	0.578
MOD_NEK2_1	89	94	PF00069	0.686
MOD_PIKK_1	170	176	PF00454	0.619
MOD_PIKK_1	187	193	PF00454	0.303
MOD_PKA_2	221	227	PF00069	0.566
MOD_PKA_2	23	29	PF00069	0.564
MOD_PKA_2	41	47	PF00069	0.466
MOD_Plk_2-3	54	60	PF00069	0.614
MOD_Plk_4	141	147	PF00069	0.460
MOD_Plk_4	164	170	PF00069	0.587
MOD_Plk_4	174	180	PF00069	0.431
MOD_Plk_4	190	196	PF00069	0.412
MOD_Plk_4	23	29	PF00069	0.615
MOD_ProDKin_1	155	161	PF00069	0.644
MOD_SUMO_for_1	218	221	PF00179	0.529
TRG_DiLeu_BaEn_1	143	148	PF01217	0.475
TRG_DiLeu_BaEn_1	23	28	PF01217	0.426
TRG_ENDOCYTIC_2	103	106	PF00928	0.612
TRG_ER_diArg_1	121	123	PF00400	0.662
TRG_ER_diArg_1	20	22	PF00400	0.525
TRG_ER_diArg_1	73	75	PF00400	0.619
TRG_ER_diArg_1	87	89	PF00400	0.493
TRG_NES_CRM1_1	137	151	PF08389	0.477
TRG_NLS_MonoExtN_4	123	130	PF00514	0.582
TRG_Pf-PMV_PEXEL_1	87	91	PF00026	0.608

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6I3	Leptomonas seymouri	51%	96%
A0A3Q8IE62	Leishmania donovani	93%	100%
A4HGZ0	Leishmania braziliensis	84%	100%
A4I422	Leishmania infantum	92%	100%
E9B0A9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%