Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q7X0_LEIMA

TriTrypDb:

LmjF.28.2920 , LMJLV39_280037700 , LMJSD75_280037300

Length:

178

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q7X0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q7X0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	38	42	PF00656	0.356
CLV_PCSK_SKI1_1	132	136	PF00082	0.361
CLV_PCSK_SKI1_1	43	47	PF00082	0.439
DEG_Nend_UBRbox_2	1	3	PF02207	0.603
DOC_CKS1_1	53	58	PF01111	0.581
DOC_MAPK_DCC_7	108	118	PF00069	0.391
DOC_MAPK_gen_1	132	141	PF00069	0.526
DOC_MAPK_gen_1	62	70	PF00069	0.497
DOC_MAPK_MEF2A_6	135	143	PF00069	0.437
DOC_MAPK_MEF2A_6	15	24	PF00069	0.487
DOC_MAPK_MEF2A_6	62	70	PF00069	0.497
DOC_PP1_RVXF_1	13	20	PF00149	0.560
DOC_PP1_RVXF_1	65	71	PF00149	0.472
DOC_PP2B_LxvP_1	95	98	PF13499	0.528
DOC_PP4_FxxP_1	117	120	PF00568	0.372
DOC_PP4_FxxP_1	80	83	PF00568	0.493
DOC_USP7_MATH_1	106	110	PF00917	0.722
DOC_USP7_MATH_1	120	124	PF00917	0.441
DOC_USP7_MATH_1	99	103	PF00917	0.549
DOC_WW_Pin1_4	141	146	PF00397	0.465
DOC_WW_Pin1_4	52	57	PF00397	0.589
LIG_14-3-3_CanoR_1	165	173	PF00244	0.509
LIG_14-3-3_CanoR_1	25	29	PF00244	0.525
LIG_Actin_WH2_2	10	27	PF00022	0.541
LIG_ActinCP_TwfCPI_2	117	124	PF01115	0.441
LIG_BIR_III_4	149	153	PF00653	0.475
LIG_FHA_1	124	130	PF00498	0.398
LIG_FHA_1	61	67	PF00498	0.385
LIG_LIR_Gen_1	146	156	PF02991	0.559
LIG_LIR_Nem_3	146	151	PF02991	0.551
LIG_LIR_Nem_3	18	22	PF02991	0.488
LIG_PCNA_yPIPBox_3	124	138	PF02747	0.349
LIG_PDZ_Class_2	173	178	PF00595	0.585
LIG_Pex14_2	70	74	PF04695	0.377
LIG_SH2_STAP1	4	8	PF00017	0.501
LIG_SH3_3	14	20	PF00018	0.559
LIG_SH3_3	50	56	PF00018	0.541
LIG_SUMO_SIM_anti_2	85	90	PF11976	0.328
MOD_CK1_1	123	129	PF00069	0.554
MOD_CK1_1	3	9	PF00069	0.538
MOD_CK2_1	156	162	PF00069	0.545
MOD_GlcNHglycan	101	104	PF01048	0.584
MOD_GlcNHglycan	108	111	PF01048	0.515
MOD_GSK3_1	152	159	PF00069	0.559
MOD_GSK3_1	43	50	PF00069	0.466
MOD_NEK2_1	24	29	PF00069	0.518
MOD_NEK2_1	70	75	PF00069	0.469
MOD_PKA_2	24	30	PF00069	0.456
MOD_Plk_1	6	12	PF00069	0.497
MOD_Plk_4	24	30	PF00069	0.402
MOD_ProDKin_1	141	147	PF00069	0.467
MOD_ProDKin_1	52	58	PF00069	0.591
MOD_SUMO_rev_2	38	45	PF00179	0.572
TRG_DiLeu_BaEn_1	18	23	PF01217	0.493
TRG_DiLeu_BaLyEn_6	61	66	PF01217	0.434

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKA8	Leptomonas seymouri	48%	98%
A0A1X0NR08	Trypanosomatidae	35%	87%
A0A3R7KM85	Trypanosoma rangeli	33%	100%
A0A3S7X216	Leishmania donovani	95%	99%
A4HGZ5	Leishmania braziliensis	81%	99%
A4I427	Leishmania infantum	95%	99%
D0A8Y0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
E9B0B4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	99%
V5ATP2	Trypanosoma cruzi	34%	100%