Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q7W5_LEIMA

TriTrypDb:

LmjF.28.2970 , LMJLV39_280038700 , LMJSD75_280038200

Length:

191

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q7W5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q7W5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	127	131	PF00656	0.552
CLV_NRD_NRD_1	14	16	PF00675	0.546
CLV_NRD_NRD_1	33	35	PF00675	0.406
CLV_PCSK_KEX2_1	112	114	PF00082	0.631
CLV_PCSK_KEX2_1	14	16	PF00082	0.693
CLV_PCSK_KEX2_1	33	35	PF00082	0.433
CLV_PCSK_KEX2_1	76	78	PF00082	0.663
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.631
CLV_PCSK_PC1ET2_1	76	78	PF00082	0.663
CLV_PCSK_PC7_1	29	35	PF00082	0.466
CLV_PCSK_SKI1_1	165	169	PF00082	0.642
CLV_PCSK_SKI1_1	73	77	PF00082	0.528
DEG_Nend_UBRbox_1	1	4	PF02207	0.482
DEG_SIAH_1	96	104	PF03145	0.510
DOC_CKS1_1	108	113	PF01111	0.500
DOC_MAPK_gen_1	146	154	PF00069	0.404
DOC_USP7_MATH_1	163	167	PF00917	0.374
DOC_USP7_MATH_1	69	73	PF00917	0.468
DOC_WW_Pin1_4	107	112	PF00397	0.501
DOC_WW_Pin1_4	81	86	PF00397	0.559
DOC_WW_Pin1_4	91	96	PF00397	0.530
LIG_14-3-3_CanoR_1	22	27	PF00244	0.493
LIG_14-3-3_CanoR_1	47	53	PF00244	0.488
LIG_eIF4E_1	175	181	PF01652	0.455
LIG_FHA_1	103	109	PF00498	0.547
LIG_FHA_1	21	27	PF00498	0.507
LIG_FHA_1	3	9	PF00498	0.509
LIG_FHA_1	47	53	PF00498	0.530
LIG_SH2_STAT5	119	122	PF00017	0.551
LIG_SH2_STAT5	175	178	PF00017	0.451
LIG_SH3_3	105	111	PF00018	0.542
LIG_SH3_3	59	65	PF00018	0.475
LIG_WRC_WIRS_1	164	169	PF05994	0.373
MOD_CDK_SPK_2	107	112	PF00069	0.501
MOD_CDK_SPxK_1	107	113	PF00069	0.502
MOD_CK1_1	133	139	PF00069	0.532
MOD_CK1_1	25	31	PF00069	0.492
MOD_CK1_1	46	52	PF00069	0.451
MOD_CK1_1	89	95	PF00069	0.573
MOD_CK2_1	141	147	PF00069	0.600
MOD_GlcNHglycan	132	135	PF01048	0.529
MOD_GlcNHglycan	158	162	PF01048	0.402
MOD_GSK3_1	103	110	PF00069	0.503
MOD_GSK3_1	125	132	PF00069	0.510
MOD_GSK3_1	39	46	PF00069	0.442
MOD_GSK3_1	65	72	PF00069	0.457
MOD_GSK3_1	86	93	PF00069	0.565
MOD_LATS_1	31	37	PF00433	0.412
MOD_PIKK_1	40	46	PF00454	0.481
MOD_PK_1	15	21	PF00069	0.514
MOD_PKA_1	33	39	PF00069	0.419
MOD_PKA_2	33	39	PF00069	0.419
MOD_PKA_2	46	52	PF00069	0.452
MOD_PKA_2	89	95	PF00069	0.573
MOD_PKB_1	20	28	PF00069	0.483
MOD_Plk_1	136	142	PF00069	0.528
MOD_Plk_4	163	169	PF00069	0.562
MOD_ProDKin_1	107	113	PF00069	0.502
MOD_ProDKin_1	81	87	PF00069	0.558
MOD_ProDKin_1	91	97	PF00069	0.526
TRG_DiLeu_BaEn_1	149	154	PF01217	0.390
TRG_ENDOCYTIC_2	60	63	PF00928	0.741
TRG_ER_diArg_1	13	15	PF00400	0.547
TRG_ER_diArg_1	19	22	PF00400	0.520
TRG_ER_diArg_1	77	80	PF00400	0.545
TRG_NLS_MonoExtC_3	75	81	PF00514	0.542
TRG_NLS_MonoExtN_4	73	80	PF00514	0.534

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9B0B9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%