Dirigent protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Dirigent protein

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q7U9_LEIMA

TriTrypDb:

LmjF.30.0070 , LMJLV39_300005700 , LMJSD75_300005700

Length:

185

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q7U9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q7U9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	14	18	PF00656	0.673
CLV_C14_Caspase3-7	87	91	PF00656	0.423
CLV_PCSK_SKI1_1	117	121	PF00082	0.394
CLV_PCSK_SKI1_1	53	57	PF00082	0.456
DOC_MAPK_gen_1	112	120	PF00069	0.641
DOC_MAPK_MEF2A_6	124	132	PF00069	0.621
DOC_MAPK_MEF2A_6	38	47	PF00069	0.685
DOC_MAPK_MEF2A_6	67	75	PF00069	0.282
DOC_PP1_RVXF_1	51	57	PF00149	0.619
DOC_WW_Pin1_4	48	53	PF00397	0.624
DOC_WW_Pin1_4	98	103	PF00397	0.282
LIG_14-3-3_CanoR_1	179	185	PF00244	0.461
LIG_14-3-3_CanoR_1	53	63	PF00244	0.651
LIG_AP2alpha_2	175	177	PF02296	0.427
LIG_APCC_ABBA_1	126	131	PF00400	0.619
LIG_BIR_III_4	17	21	PF00653	0.662
LIG_BRCT_BRCA1_1	106	110	PF00533	0.339
LIG_BRCT_BRCA1_1	71	75	PF00533	0.339
LIG_EH1_1	78	86	PF00400	0.333
LIG_FHA_1	121	127	PF00498	0.661
LIG_FHA_1	99	105	PF00498	0.282
LIG_FHA_2	12	18	PF00498	0.631
LIG_LIR_Gen_1	107	118	PF02991	0.602
LIG_LIR_Gen_1	127	136	PF02991	0.559
LIG_LIR_Gen_1	92	103	PF02991	0.250
LIG_LIR_Nem_3	107	113	PF02991	0.375
LIG_LIR_Nem_3	127	132	PF02991	0.563
LIG_LIR_Nem_3	92	98	PF02991	0.250
LIG_NRBOX	151	157	PF00104	0.296
LIG_PCNA_yPIPBox_3	166	179	PF02747	0.414
LIG_Pex14_2	106	110	PF04695	0.339
LIG_Pex14_2	75	79	PF04695	0.375
LIG_SH2_PTP2	129	132	PF00017	0.673
LIG_SH2_SRC	129	132	PF00017	0.621
LIG_SH2_SRC	61	64	PF00017	0.643
LIG_SH2_STAT5	129	132	PF00017	0.673
LIG_SH2_STAT5	154	157	PF00017	0.308
LIG_SH2_STAT5	61	64	PF00017	0.647
LIG_SH2_STAT5	97	100	PF00017	0.282
LIG_SH3_3	116	122	PF00018	0.600
LIG_SH3_3	68	74	PF00018	0.339
LIG_SUMO_SIM_anti_2	80	87	PF11976	0.469
LIG_SUMO_SIM_par_1	80	87	PF11976	0.469
LIG_SxIP_EBH_1	53	65	PF03271	0.653
MOD_CDK_SPK_2	48	53	PF00069	0.624
MOD_CK1_1	108	114	PF00069	0.652
MOD_GlcNHglycan	107	110	PF01048	0.292
MOD_GlcNHglycan	32	36	PF01048	0.485
MOD_GlcNHglycan	98	101	PF01048	0.282
MOD_GSK3_1	104	111	PF00069	0.325
MOD_NEK2_1	104	109	PF00069	0.339
MOD_NEK2_1	77	82	PF00069	0.349
MOD_NEK2_1	96	101	PF00069	0.339
MOD_NMyristoyl	1	7	PF02799	0.671
MOD_PIKK_1	162	168	PF00454	0.455
MOD_PIKK_1	54	60	PF00454	0.653
MOD_PKA_2	178	184	PF00069	0.453
MOD_Plk_1	69	75	PF00069	0.282
MOD_Plk_4	80	86	PF00069	0.508
MOD_Plk_4	91	97	PF00069	0.384
MOD_ProDKin_1	48	54	PF00069	0.622
MOD_ProDKin_1	98	104	PF00069	0.282
MOD_SUMO_for_1	37	40	PF00179	0.672
TRG_DiLeu_BaEn_2	130	136	PF01217	0.614
TRG_ENDOCYTIC_2	129	132	PF00928	0.673
TRG_ENDOCYTIC_2	141	144	PF00928	0.587
TRG_ER_diArg_1	24	27	PF00400	0.618

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P2B5	Trypanosomatidae	68%	68%
A0A3Q8IEJ7	Leishmania donovani	99%	100%
A4HHV2	Leishmania braziliensis	96%	100%
A4I502	Leishmania infantum	99%	100%
C9ZQF1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	66%
E9B0D2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%