Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q7S9_LEIMA

TriTrypDb:

LmjF.30.0300 , LMJLV39_300008300 , LMJSD75_300008200

Length:

148

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q7S9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q7S9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	6	12	PF00089	0.586
CLV_NRD_NRD_1	62	64	PF00675	0.715
CLV_PCSK_KEX2_1	62	64	PF00082	0.689
CLV_PCSK_SKI1_1	25	29	PF00082	0.527
DOC_CYCLIN_yCln2_LP_2	36	42	PF00134	0.668
DOC_PP2B_LxvP_1	36	39	PF13499	0.704
DOC_USP7_MATH_1	127	131	PF00917	0.729
DOC_USP7_MATH_1	71	75	PF00917	0.622
DOC_WW_Pin1_4	104	109	PF00397	0.568
LIG_14-3-3_CanoR_1	30	40	PF00244	0.665
LIG_14-3-3_CanoR_1	9	16	PF00244	0.604
LIG_14-3-3_CanoR_1	93	99	PF00244	0.551
LIG_BIR_II_1	1	5	PF00653	0.707
LIG_BRCT_BRCA1_1	129	133	PF00533	0.655
LIG_BRCT_BRCA1_1	79	83	PF00533	0.543
LIG_deltaCOP1_diTrp_1	124	133	PF00928	0.655
LIG_FHA_1	109	115	PF00498	0.658
LIG_FHA_1	74	80	PF00498	0.613
LIG_FHA_2	105	111	PF00498	0.583
LIG_FHA_2	80	86	PF00498	0.604
LIG_IRF3_LxIS_1	36	41	PF10401	0.676
LIG_LIR_Apic_2	11	16	PF02991	0.633
LIG_LIR_Gen_1	106	117	PF02991	0.639
LIG_LIR_Nem_3	106	112	PF02991	0.653
LIG_LIR_Nem_3	80	86	PF02991	0.635
LIG_NRBOX	113	119	PF00104	0.494
LIG_NRBOX	2	8	PF00104	0.701
LIG_Pex14_2	23	27	PF04695	0.491
LIG_PTB_Apo_2	78	85	PF02174	0.645
LIG_SH2_CRK	109	113	PF00017	0.650
LIG_SH2_NCK_1	109	113	PF00017	0.643
LIG_SH2_PTP2	13	16	PF00017	0.626
LIG_SH2_STAT5	13	16	PF00017	0.626
LIG_SUMO_SIM_par_1	110	116	PF11976	0.662
LIG_TYR_ITSM	105	112	PF00017	0.626
MOD_CK1_1	113	119	PF00069	0.682
MOD_CK1_1	29	35	PF00069	0.682
MOD_CK1_1	43	49	PF00069	0.537
MOD_CK2_1	54	60	PF00069	0.645
MOD_CK2_1	71	77	PF00069	0.622
MOD_Cter_Amidation	60	63	PF01082	0.660
MOD_GlcNHglycan	18	21	PF01048	0.634
MOD_GlcNHglycan	3	6	PF01048	0.673
MOD_GlcNHglycan	40	43	PF01048	0.718
MOD_GSK3_1	26	33	PF00069	0.635
MOD_GSK3_1	38	45	PF00069	0.596
MOD_GSK3_1	50	57	PF00069	0.552
MOD_GSK3_1	73	80	PF00069	0.594
MOD_GSK3_1	98	105	PF00069	0.567
MOD_NEK2_1	1	6	PF00069	0.640
MOD_NEK2_1	44	49	PF00069	0.686
MOD_NEK2_2	54	59	PF00069	0.643
MOD_NEK2_2	8	13	PF00069	0.630
MOD_PKA_2	29	35	PF00069	0.642
MOD_PKA_2	8	14	PF00069	0.653
MOD_PKA_2	92	98	PF00069	0.533
MOD_Plk_2-3	110	116	PF00069	0.649
MOD_Plk_2-3	73	79	PF00069	0.616
MOD_Plk_4	113	119	PF00069	0.585
MOD_Plk_4	45	51	PF00069	0.609
MOD_Plk_4	79	85	PF00069	0.656
MOD_ProDKin_1	104	110	PF00069	0.570
TRG_DiLeu_BaEn_1	136	141	PF01217	0.557
TRG_DiLeu_BaEn_2	128	134	PF01217	0.648
TRG_ENDOCYTIC_2	109	112	PF00928	0.666
TRG_ENDOCYTIC_2	24	27	PF00928	0.649

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM95	Leptomonas seymouri	54%	95%
A0A3S7X2Y5	Leishmania donovani	95%	100%
A0A422NMM9	Trypanosoma rangeli	39%	100%
A4HHX4	Leishmania braziliensis	80%	99%
A4I524	Leishmania infantum	95%	100%
C9ZQI2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
E9B0F4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%