Homologous to other Eukaryotic mitochondrial proteins. Likely non-TM.
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 25 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 13 |
| NetGPI | no | yes: 0, no: 13 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0001405 | PAM complex, Tim23 associated import motor | 4 | 3 |
| GO:0032991 | protein-containing complex | 1 | 3 |
| GO:0098796 | membrane protein complex | 2 | 3 |
| GO:0098798 | mitochondrial protein-containing complex | 2 | 3 |
| GO:0098800 | inner mitochondrial membrane protein complex | 3 | 3 |
| GO:0005759 | mitochondrial matrix | 5 | 6 |
| GO:0031974 | membrane-enclosed lumen | 2 | 6 |
| GO:0043233 | organelle lumen | 3 | 6 |
| GO:0070013 | intracellular organelle lumen | 4 | 6 |
| GO:0110165 | cellular anatomical entity | 1 | 7 |
| GO:0016020 | membrane | 2 | 1 |
Related structures:
AlphaFold database: Q4Q7N3
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006457 | protein folding | 2 | 14 |
| GO:0006810 | transport | 3 | 3 |
| GO:0006839 | mitochondrial transport | 4 | 3 |
| GO:0006886 | intracellular protein transport | 4 | 3 |
| GO:0008104 | protein localization | 4 | 3 |
| GO:0009987 | cellular process | 1 | 14 |
| GO:0015031 | protein transport | 4 | 3 |
| GO:0030150 | protein import into mitochondrial matrix | 4 | 3 |
| GO:0033036 | macromolecule localization | 2 | 3 |
| GO:0033365 | protein localization to organelle | 5 | 3 |
| GO:0044743 | protein transmembrane import into intracellular organelle | 4 | 3 |
| GO:0045184 | establishment of protein localization | 3 | 3 |
| GO:0046907 | intracellular transport | 3 | 3 |
| GO:0051179 | localization | 1 | 3 |
| GO:0051234 | establishment of localization | 2 | 3 |
| GO:0051641 | cellular localization | 2 | 3 |
| GO:0051649 | establishment of localization in cell | 3 | 3 |
| GO:0055085 | transmembrane transport | 2 | 3 |
| GO:0065002 | intracellular protein transmembrane transport | 4 | 3 |
| GO:0070585 | protein localization to mitochondrion | 6 | 3 |
| GO:0070727 | cellular macromolecule localization | 3 | 3 |
| GO:0071702 | organic substance transport | 4 | 3 |
| GO:0071705 | nitrogen compound transport | 4 | 3 |
| GO:0071806 | protein transmembrane transport | 3 | 3 |
| GO:0072594 | establishment of protein localization to organelle | 4 | 3 |
| GO:0072655 | establishment of protein localization to mitochondrion | 5 | 3 |
| GO:1990542 | mitochondrial transmembrane transport | 3 | 3 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000166 | nucleotide binding | 3 | 14 |
| GO:0000774 | adenyl-nucleotide exchange factor activity | 3 | 14 |
| GO:0005488 | binding | 1 | 14 |
| GO:0005515 | protein binding | 2 | 14 |
| GO:0017076 | purine nucleotide binding | 4 | 14 |
| GO:0030554 | adenyl nucleotide binding | 5 | 14 |
| GO:0036094 | small molecule binding | 2 | 14 |
| GO:0042802 | identical protein binding | 3 | 14 |
| GO:0042803 | protein homodimerization activity | 4 | 14 |
| GO:0046983 | protein dimerization activity | 3 | 14 |
| GO:0051082 | unfolded protein binding | 3 | 3 |
| GO:0051087 | protein-folding chaperone binding | 3 | 14 |
| GO:0060590 | ATPase regulator activity | 2 | 14 |
| GO:0097159 | organic cyclic compound binding | 2 | 14 |
| GO:0098772 | molecular function regulator activity | 1 | 14 |
| GO:1901265 | nucleoside phosphate binding | 3 | 14 |
| GO:1901363 | heterocyclic compound binding | 2 | 14 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 123 | 125 | PF00675 | 0.293 |
| CLV_NRD_NRD_1 | 246 | 248 | PF00675 | 0.308 |
| CLV_NRD_NRD_1 | 71 | 73 | PF00675 | 0.693 |
| CLV_PCSK_KEX2_1 | 103 | 105 | PF00082 | 0.352 |
| CLV_PCSK_KEX2_1 | 193 | 195 | PF00082 | 0.305 |
| CLV_PCSK_KEX2_1 | 246 | 248 | PF00082 | 0.250 |
| CLV_PCSK_PC1ET2_1 | 103 | 105 | PF00082 | 0.352 |
| CLV_PCSK_PC1ET2_1 | 193 | 195 | PF00082 | 0.305 |
| CLV_PCSK_SKI1_1 | 124 | 128 | PF00082 | 0.357 |
| CLV_PCSK_SKI1_1 | 144 | 148 | PF00082 | 0.278 |
| CLV_PCSK_SKI1_1 | 159 | 163 | PF00082 | 0.285 |
| CLV_PCSK_SKI1_1 | 190 | 194 | PF00082 | 0.351 |
| CLV_PCSK_SKI1_1 | 215 | 219 | PF00082 | 0.250 |
| DEG_SCF_FBW7_1 | 23 | 29 | PF00400 | 0.373 |
| DEG_SPOP_SBC_1 | 26 | 30 | PF00917 | 0.370 |
| DOC_CKS1_1 | 220 | 225 | PF01111 | 0.488 |
| DOC_CKS1_1 | 23 | 28 | PF01111 | 0.374 |
| DOC_MAPK_gen_1 | 246 | 252 | PF00069 | 0.493 |
| DOC_MAPK_RevD_3 | 58 | 73 | PF00069 | 0.451 |
| DOC_PP4_FxxP_1 | 217 | 220 | PF00568 | 0.505 |
| DOC_USP7_MATH_1 | 116 | 120 | PF00917 | 0.426 |
| DOC_USP7_MATH_1 | 138 | 142 | PF00917 | 0.450 |
| DOC_WW_Pin1_4 | 219 | 224 | PF00397 | 0.450 |
| DOC_WW_Pin1_4 | 22 | 27 | PF00397 | 0.377 |
| DOC_WW_Pin1_4 | 41 | 46 | PF00397 | 0.415 |
| LIG_14-3-3_CanoR_1 | 194 | 204 | PF00244 | 0.450 |
| LIG_14-3-3_CanoR_1 | 54 | 63 | PF00244 | 0.598 |
| LIG_FHA_1 | 155 | 161 | PF00498 | 0.418 |
| LIG_FHA_1 | 182 | 188 | PF00498 | 0.426 |
| LIG_FHA_1 | 220 | 226 | PF00498 | 0.471 |
| LIG_FHA_1 | 27 | 33 | PF00498 | 0.393 |
| LIG_FHA_1 | 78 | 84 | PF00498 | 0.674 |
| LIG_FHA_2 | 42 | 48 | PF00498 | 0.387 |
| LIG_LIR_Apic_2 | 214 | 220 | PF02991 | 0.463 |
| LIG_Pex14_2 | 35 | 39 | PF04695 | 0.392 |
| LIG_SH2_NCK_1 | 115 | 119 | PF00017 | 0.450 |
| LIG_SH2_NCK_1 | 18 | 22 | PF00017 | 0.364 |
| LIG_SH2_STAT5 | 163 | 166 | PF00017 | 0.439 |
| LIG_SH3_3 | 217 | 223 | PF00018 | 0.569 |
| LIG_SUMO_SIM_par_1 | 145 | 151 | PF11976 | 0.492 |
| LIG_SxIP_EBH_1 | 163 | 172 | PF03271 | 0.426 |
| LIG_TRAF2_1 | 126 | 129 | PF00917 | 0.450 |
| LIG_Vh1_VBS_1 | 146 | 164 | PF01044 | 0.394 |
| LIG_WRC_WIRS_1 | 139 | 144 | PF05994 | 0.516 |
| MOD_CDK_SPK_2 | 41 | 46 | PF00069 | 0.410 |
| MOD_CDK_SPxxK_3 | 219 | 226 | PF00069 | 0.488 |
| MOD_CK1_1 | 19 | 25 | PF00069 | 0.522 |
| MOD_CK1_1 | 221 | 227 | PF00069 | 0.512 |
| MOD_CK1_1 | 41 | 47 | PF00069 | 0.643 |
| MOD_CK2_1 | 221 | 227 | PF00069 | 0.543 |
| MOD_CK2_1 | 81 | 87 | PF00069 | 0.586 |
| MOD_GlcNHglycan | 56 | 59 | PF01048 | 0.622 |
| MOD_GSK3_1 | 124 | 131 | PF00069 | 0.491 |
| MOD_GSK3_1 | 161 | 168 | PF00069 | 0.490 |
| MOD_GSK3_1 | 195 | 202 | PF00069 | 0.505 |
| MOD_GSK3_1 | 215 | 222 | PF00069 | 0.573 |
| MOD_GSK3_1 | 22 | 29 | PF00069 | 0.377 |
| MOD_GSK3_1 | 73 | 80 | PF00069 | 0.616 |
| MOD_N-GLC_1 | 166 | 171 | PF02516 | 0.294 |
| MOD_N-GLC_1 | 240 | 245 | PF02516 | 0.305 |
| MOD_NEK2_1 | 240 | 245 | PF00069 | 0.471 |
| MOD_NEK2_1 | 63 | 68 | PF00069 | 0.613 |
| MOD_NEK2_1 | 99 | 104 | PF00069 | 0.585 |
| MOD_PIKK_1 | 124 | 130 | PF00454 | 0.450 |
| MOD_PIKK_1 | 161 | 167 | PF00454 | 0.426 |
| MOD_PIKK_1 | 195 | 201 | PF00454 | 0.450 |
| MOD_PK_1 | 166 | 172 | PF00069 | 0.434 |
| MOD_PK_1 | 226 | 232 | PF00069 | 0.488 |
| MOD_PKA_1 | 124 | 130 | PF00069 | 0.450 |
| MOD_PKA_2 | 165 | 171 | PF00069 | 0.434 |
| MOD_Plk_1 | 166 | 172 | PF00069 | 0.502 |
| MOD_Plk_4 | 240 | 246 | PF00069 | 0.483 |
| MOD_Plk_4 | 27 | 33 | PF00069 | 0.380 |
| MOD_ProDKin_1 | 219 | 225 | PF00069 | 0.450 |
| MOD_ProDKin_1 | 22 | 28 | PF00069 | 0.373 |
| MOD_ProDKin_1 | 41 | 47 | PF00069 | 0.416 |
| MOD_SUMO_for_1 | 171 | 174 | PF00179 | 0.514 |
| MOD_SUMO_rev_2 | 209 | 217 | PF00179 | 0.542 |
| TRG_DiLeu_BaLyEn_6 | 59 | 64 | PF01217 | 0.473 |
| TRG_ENDOCYTIC_2 | 92 | 95 | PF00928 | 0.463 |
| TRG_ER_diArg_1 | 245 | 247 | PF00400 | 0.450 |
| TRG_Pf-PMV_PEXEL_1 | 104 | 108 | PF00026 | 0.289 |
| TRG_Pf-PMV_PEXEL_1 | 46 | 50 | PF00026 | 0.534 |
| TRG_Pf-PMV_PEXEL_1 | 8 | 13 | PF00026 | 0.356 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1HZM2 | Leptomonas seymouri | 45% | 100% |
| A0A0N1ILR2 | Leptomonas seymouri | 30% | 100% |
| A0A0S4JEA6 | Bodo saltans | 33% | 100% |
| A0A1X0P2B4 | Trypanosomatidae | 30% | 100% |
| A0A3Q8IEN8 | Leishmania donovani | 91% | 100% |
| A0A3Q8IJ81 | Leishmania donovani | 32% | 100% |
| A0A422P4T2 | Trypanosoma rangeli | 25% | 100% |
| A0KZB0 | Shewanella sp. (strain ANA-3) | 23% | 100% |
| A1UUC9 | Bartonella bacilliformis (strain ATCC 35685 / NCTC 12138 / KC583) | 29% | 100% |
| A3MZ85 | Actinobacillus pleuropneumoniae serotype 5b (strain L20) | 26% | 100% |
| A4HI25 | Leishmania braziliensis | 32% | 100% |
| A4HI26 | Leishmania braziliensis | 67% | 100% |
| A4I5A2 | Leishmania infantum | 32% | 100% |
| A4I5A3 | Leishmania infantum | 94% | 100% |
| A4IX27 | Francisella tularensis subsp. tularensis (strain WY96-3418) | 26% | 100% |
| A4SQ26 | Aeromonas salmonicida (strain A449) | 25% | 100% |
| A4XYF7 | Pseudomonas mendocina (strain ymp) | 28% | 100% |
| A5F369 | Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395) | 25% | 100% |
| A5W9A4 | Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) | 26% | 100% |
| A6VMQ9 | Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z) | 24% | 100% |
| A8FYL1 | Shewanella sediminis (strain HAW-EB3) | 26% | 100% |
| A9ILE9 | Bartonella tribocorum (strain CIP 105476 / IBS 506) | 27% | 100% |
| B0BTB9 | Actinobacillus pleuropneumoniae serotype 3 (strain JL03) | 26% | 100% |
| B1XRU2 | Polynucleobacter necessarius subsp. necessarius (strain STIR1) | 26% | 100% |
| B3EPC6 | Chlorobium phaeobacteroides (strain BS1) | 26% | 100% |
| B3H0M9 | Actinobacillus pleuropneumoniae serotype 7 (strain AP76) | 26% | 100% |
| B7VJW7 | Vibrio atlanticus (strain LGP32) | 26% | 100% |
| C0QX60 | Brachyspira hyodysenteriae (strain ATCC 49526 / WA1) | 26% | 100% |
| C1DFM4 | Azotobacter vinelandii (strain DJ / ATCC BAA-1303) | 27% | 100% |
| C3LTA4 | Vibrio cholerae serotype O1 (strain M66-2) | 25% | 100% |
| C6D9J8 | Pectobacterium carotovorum subsp. carotovorum (strain PC1) | 28% | 100% |
| C9ZQN6 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 32% | 100% |
| E9B0J8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 31% | 100% |
| E9B0J9 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 88% | 100% |
| O30862 | Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) | 25% | 100% |
| O88396 | Mus musculus | 29% | 100% |
| P38523 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 24% | 100% |
| Q0HGL4 | Shewanella sp. (strain MR-4) | 23% | 100% |
| Q0HSW5 | Shewanella sp. (strain MR-7) | 23% | 100% |
| Q0P5N5 | Bos taurus | 28% | 100% |
| Q14GW8 | Francisella tularensis subsp. tularensis (strain FSC 198) | 26% | 100% |
| Q2G6M5 | Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199) | 25% | 100% |
| Q2JVR0 | Synechococcus sp. (strain JA-3-3Ab) | 25% | 100% |
| Q3KIA1 | Pseudomonas fluorescens (strain Pf0-1) | 24% | 100% |
| Q3MG83 | Trichormus variabilis (strain ATCC 29413 / PCC 7937) | 29% | 100% |
| Q3YSZ3 | Ehrlichia canis (strain Jake) | 25% | 100% |
| Q4KIH2 | Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) | 25% | 100% |
| Q4Q7N4 | Leishmania major | 32% | 100% |
| Q5NFG6 | Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4) | 26% | 100% |
| Q5R435 | Pongo abelii | 27% | 100% |
| Q5RA81 | Pongo abelii | 28% | 100% |
| Q6BTP9 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 28% | 100% |
| Q6CRQ1 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 27% | 100% |
| Q75C01 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 30% | 100% |
| Q7UA77 | Parasynechococcus marenigrum (strain WH8102) | 26% | 100% |
| Q7VMB7 | Haemophilus ducreyi (strain 35000HP / ATCC 700724) | 28% | 100% |
| Q88DU1 | Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) | 26% | 100% |
| Q8EGS0 | Shewanella oneidensis (strain MR-1) | 23% | 100% |
| Q8TAA5 | Homo sapiens | 27% | 100% |
| Q8YUA7 | Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) | 26% | 100% |
| Q9HAV7 | Homo sapiens | 28% | 100% |
| Q9P5U4 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 30% | 100% |