Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q7N1_LEIMA

TriTrypDb:

LmjF.30.0745 , LMJLV39_300013300 , LMJSD75_300013100

Length:

279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q7N1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q7N1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	102	106	PF00656	0.619
CLV_NRD_NRD_1	4	6	PF00675	0.561
CLV_NRD_NRD_1	94	96	PF00675	0.639
CLV_PCSK_FUR_1	92	96	PF00082	0.500
CLV_PCSK_KEX2_1	4	6	PF00082	0.577
CLV_PCSK_KEX2_1	55	57	PF00082	0.752
CLV_PCSK_KEX2_1	91	93	PF00082	0.642
CLV_PCSK_KEX2_1	94	96	PF00082	0.616
CLV_PCSK_PC1ET2_1	55	57	PF00082	0.602
CLV_PCSK_PC1ET2_1	91	93	PF00082	0.642
CLV_PCSK_SKI1_1	127	131	PF00082	0.615
CLV_PCSK_SKI1_1	98	102	PF00082	0.552
DEG_COP1_1	69	78	PF00400	0.490
DEG_Nend_Nbox_1	1	3	PF02207	0.640
DOC_CDC14_PxL_1	157	165	PF14671	0.504
DOC_PP1_RVXF_1	12	19	PF00149	0.674
DOC_USP7_MATH_1	116	120	PF00917	0.549
DOC_USP7_MATH_1	190	194	PF00917	0.600
DOC_USP7_MATH_1	231	235	PF00917	0.545
DOC_USP7_MATH_1	31	35	PF00917	0.729
DOC_USP7_MATH_1	62	66	PF00917	0.762
DOC_USP7_MATH_1	68	72	PF00917	0.596
DOC_USP7_MATH_1	76	80	PF00917	0.628
DOC_WW_Pin1_4	140	145	PF00397	0.643
DOC_WW_Pin1_4	55	60	PF00397	0.608
LIG_14-3-3_CanoR_1	7	16	PF00244	0.531
LIG_FHA_1	113	119	PF00498	0.601
LIG_FHA_1	194	200	PF00498	0.566
LIG_FHA_1	99	105	PF00498	0.491
LIG_LIR_Gen_1	146	155	PF02991	0.542
LIG_LIR_Gen_1	69	78	PF02991	0.467
LIG_LIR_Nem_3	146	150	PF02991	0.551
LIG_LIR_Nem_3	69	75	PF02991	0.484
LIG_NRBOX	103	109	PF00104	0.548
LIG_SH2_CRK	205	209	PF00017	0.382
LIG_SH2_NCK_1	205	209	PF00017	0.367
LIG_SH2_PTP2	263	266	PF00017	0.475
LIG_SH2_SRC	123	126	PF00017	0.619
LIG_SH2_STAT5	123	126	PF00017	0.490
LIG_SH2_STAT5	263	266	PF00017	0.475
LIG_SH3_3	175	181	PF00018	0.440
LIG_SH3_3	184	190	PF00018	0.490
LIG_TRAF2_1	100	103	PF00917	0.572
LIG_TRAF2_1	143	146	PF00917	0.655
MOD_CDK_SPK_2	55	60	PF00069	0.712
MOD_CK1_1	111	117	PF00069	0.528
MOD_CK1_1	166	172	PF00069	0.461
MOD_CK1_1	193	199	PF00069	0.458
MOD_CK1_1	71	77	PF00069	0.572
MOD_CK2_1	131	137	PF00069	0.464
MOD_CK2_1	140	146	PF00069	0.475
MOD_CK2_1	150	156	PF00069	0.460
MOD_CMANNOS	15	18	PF00535	0.614
MOD_GlcNHglycan	119	122	PF01048	0.660
MOD_GlcNHglycan	134	137	PF01048	0.437
MOD_GlcNHglycan	165	168	PF01048	0.556
MOD_GlcNHglycan	227	230	PF01048	0.402
MOD_GlcNHglycan	63	67	PF01048	0.704
MOD_GSK3_1	108	115	PF00069	0.575
MOD_GSK3_1	128	135	PF00069	0.330
MOD_GSK3_1	166	173	PF00069	0.518
MOD_GSK3_1	176	183	PF00069	0.417
MOD_GSK3_1	219	226	PF00069	0.449
MOD_GSK3_1	62	69	PF00069	0.671
MOD_GSK3_1	74	81	PF00069	0.606
MOD_N-GLC_1	108	113	PF02516	0.518
MOD_N-GLC_1	269	274	PF02516	0.335
MOD_NEK2_1	108	113	PF00069	0.518
MOD_NEK2_1	150	155	PF00069	0.609
MOD_NEK2_1	163	168	PF00069	0.479
MOD_NEK2_1	212	217	PF00069	0.512
MOD_NEK2_1	61	66	PF00069	0.695
MOD_NEK2_2	47	52	PF00069	0.662
MOD_PIKK_1	8	14	PF00454	0.530
MOD_PK_1	22	28	PF00069	0.749
MOD_PKA_1	7	13	PF00069	0.599
MOD_PKA_2	112	118	PF00069	0.540
MOD_PKA_2	163	169	PF00069	0.613
MOD_PKB_1	5	13	PF00069	0.482
MOD_Plk_1	269	275	PF00069	0.342
MOD_Plk_1	47	53	PF00069	0.687
MOD_Plk_4	128	134	PF00069	0.627
MOD_Plk_4	170	176	PF00069	0.397
MOD_Plk_4	22	28	PF00069	0.640
MOD_Plk_4	269	275	PF00069	0.430
MOD_ProDKin_1	140	146	PF00069	0.647
MOD_ProDKin_1	55	61	PF00069	0.610
MOD_SUMO_rev_2	146	155	PF00179	0.402
MOD_SUMO_rev_2	77	83	PF00179	0.501
TRG_DiLeu_BaEn_1	103	108	PF01217	0.571
TRG_ER_diArg_1	3	5	PF00400	0.623
TRG_ER_diArg_1	92	95	PF00400	0.609
TRG_NLS_MonoExtC_3	90	95	PF00514	0.503
TRG_NLS_MonoExtN_4	89	95	PF00514	0.502
TRG_Pf-PMV_PEXEL_1	95	99	PF00026	0.491

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFH4	Leptomonas seymouri	49%	100%
A0A0S4JGE4	Bodo saltans	31%	81%
A0A1X0P245	Trypanosomatidae	33%	89%
A0A3S7X369	Leishmania donovani	96%	100%
A0A422P4T3	Trypanosoma rangeli	34%	99%
A4HI29	Leishmania braziliensis	86%	100%
A4I5A5	Leishmania infantum	96%	100%
C9ZQN9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	97%
E9B0K1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
V5BUA0	Trypanosoma cruzi	35%	99%