PSP1 C-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PSP1 C-terminal conserved region, putative

Species:

Leishmania major

UniProt:

Q4Q7G7_LEIMA

TriTrypDb:

LmjF.30.1370 , LMJLV39_300020300 , LMJSD75_300020000

Length:

900

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q7G7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q7G7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	209	213	PF00656	0.649
CLV_C14_Caspase3-7	706	710	PF00656	0.677
CLV_NRD_NRD_1	232	234	PF00675	0.822
CLV_NRD_NRD_1	316	318	PF00675	0.691
CLV_NRD_NRD_1	493	495	PF00675	0.732
CLV_NRD_NRD_1	514	516	PF00675	0.587
CLV_NRD_NRD_1	573	575	PF00675	0.657
CLV_NRD_NRD_1	640	642	PF00675	0.749
CLV_NRD_NRD_1	790	792	PF00675	0.695
CLV_NRD_NRD_1	801	803	PF00675	0.331
CLV_PCSK_KEX2_1	231	233	PF00082	0.832
CLV_PCSK_KEX2_1	316	318	PF00082	0.691
CLV_PCSK_KEX2_1	493	495	PF00082	0.732
CLV_PCSK_KEX2_1	514	516	PF00082	0.587
CLV_PCSK_KEX2_1	573	575	PF00082	0.657
CLV_PCSK_KEX2_1	640	642	PF00082	0.692
CLV_PCSK_KEX2_1	719	721	PF00082	0.782
CLV_PCSK_KEX2_1	887	889	PF00082	0.525
CLV_PCSK_PC1ET2_1	719	721	PF00082	0.782
CLV_PCSK_PC1ET2_1	887	889	PF00082	0.525
CLV_PCSK_PC7_1	883	889	PF00082	0.450
CLV_PCSK_SKI1_1	694	698	PF00082	0.659
CLV_PCSK_SKI1_1	713	717	PF00082	0.591
CLV_PCSK_SKI1_1	733	737	PF00082	0.771
CLV_PCSK_SKI1_1	807	811	PF00082	0.439
CLV_PCSK_SKI1_1	821	825	PF00082	0.284
CLV_PCSK_SKI1_1	874	878	PF00082	0.392
CLV_PCSK_SKI1_1	883	887	PF00082	0.361
CLV_Separin_Metazoa	205	209	PF03568	0.641
DEG_APCC_DBOX_1	732	740	PF00400	0.647
DEG_SCF_FBW7_1	191	196	PF00400	0.674
DEG_SCF_FBW7_1	770	776	PF00400	0.619
DEG_SPOP_SBC_1	422	426	PF00917	0.777
DEG_SPOP_SBC_1	616	620	PF00917	0.714
DOC_CKS1_1	128	133	PF01111	0.789
DOC_CKS1_1	152	157	PF01111	0.753
DOC_CKS1_1	190	195	PF01111	0.652
DOC_CKS1_1	298	303	PF01111	0.814
DOC_CKS1_1	58	63	PF01111	0.771
DOC_CKS1_1	770	775	PF01111	0.613
DOC_CYCLIN_RxL_1	730	740	PF00134	0.768
DOC_CYCLIN_RxL_1	802	814	PF00134	0.379
DOC_CYCLIN_yCln2_LP_2	248	251	PF00134	0.733
DOC_CYCLIN_yCln2_LP_2	89	95	PF00134	0.806
DOC_MAPK_gen_1	573	583	PF00069	0.715
DOC_MAPK_gen_1	791	797	PF00069	0.450
DOC_MAPK_gen_1	802	810	PF00069	0.509
DOC_MAPK_gen_1	821	830	PF00069	0.288
DOC_MAPK_MEF2A_6	157	165	PF00069	0.622
DOC_PP1_RVXF_1	872	879	PF00149	0.411
DOC_PP2B_LxvP_1	248	251	PF13499	0.733
DOC_PP2B_LxvP_1	532	535	PF13499	0.753
DOC_PP2B_LxvP_1	93	96	PF13499	0.740
DOC_PP4_FxxP_1	173	176	PF00568	0.749
DOC_USP7_MATH_1	122	126	PF00917	0.755
DOC_USP7_MATH_1	134	138	PF00917	0.612
DOC_USP7_MATH_1	143	147	PF00917	0.692
DOC_USP7_MATH_1	217	221	PF00917	0.740
DOC_USP7_MATH_1	227	231	PF00917	0.678
DOC_USP7_MATH_1	244	248	PF00917	0.708
DOC_USP7_MATH_1	253	257	PF00917	0.763
DOC_USP7_MATH_1	330	334	PF00917	0.744
DOC_USP7_MATH_1	364	368	PF00917	0.817
DOC_USP7_MATH_1	370	374	PF00917	0.717
DOC_USP7_MATH_1	39	43	PF00917	0.796
DOC_USP7_MATH_1	47	51	PF00917	0.625
DOC_USP7_MATH_1	504	508	PF00917	0.647
DOC_USP7_MATH_1	545	549	PF00917	0.762
DOC_USP7_MATH_1	616	620	PF00917	0.775
DOC_USP7_MATH_1	635	639	PF00917	0.632
DOC_USP7_MATH_1	663	667	PF00917	0.633
DOC_USP7_MATH_1	731	735	PF00917	0.586
DOC_USP7_MATH_1	773	777	PF00917	0.579
DOC_USP7_MATH_1	854	858	PF00917	0.407
DOC_USP7_MATH_1	867	871	PF00917	0.487
DOC_USP7_MATH_2	755	761	PF00917	0.611
DOC_WW_Pin1_4	127	132	PF00397	0.707
DOC_WW_Pin1_4	14	19	PF00397	0.811
DOC_WW_Pin1_4	151	156	PF00397	0.699
DOC_WW_Pin1_4	172	177	PF00397	0.705
DOC_WW_Pin1_4	189	194	PF00397	0.688
DOC_WW_Pin1_4	212	217	PF00397	0.677
DOC_WW_Pin1_4	223	228	PF00397	0.730
DOC_WW_Pin1_4	27	32	PF00397	0.818
DOC_WW_Pin1_4	275	280	PF00397	0.703
DOC_WW_Pin1_4	297	302	PF00397	0.717
DOC_WW_Pin1_4	448	453	PF00397	0.598
DOC_WW_Pin1_4	57	62	PF00397	0.725
DOC_WW_Pin1_4	69	74	PF00397	0.755
DOC_WW_Pin1_4	751	756	PF00397	0.601
DOC_WW_Pin1_4	769	774	PF00397	0.578
DOC_WW_Pin1_4	88	93	PF00397	0.562
LIG_14-3-3_CanoR_1	281	285	PF00244	0.821
LIG_14-3-3_CanoR_1	305	312	PF00244	0.810
LIG_14-3-3_CanoR_1	423	431	PF00244	0.782
LIG_14-3-3_CanoR_1	434	441	PF00244	0.663
LIG_14-3-3_CanoR_1	555	565	PF00244	0.613
LIG_14-3-3_CanoR_1	56	61	PF00244	0.797
LIG_14-3-3_CanoR_1	602	607	PF00244	0.839
LIG_14-3-3_CanoR_1	651	659	PF00244	0.748
LIG_14-3-3_CanoR_1	85	89	PF00244	0.759
LIG_14-3-3_CanoR_1	865	873	PF00244	0.522
LIG_14-3-3_CanoR_1	892	897	PF00244	0.508
LIG_Actin_WH2_2	778	793	PF00022	0.699
LIG_BRCT_BRCA1_1	432	436	PF00533	0.706
LIG_FHA_1	106	112	PF00498	0.797
LIG_FHA_1	194	200	PF00498	0.676
LIG_FHA_1	323	329	PF00498	0.709
LIG_FHA_1	363	369	PF00498	0.587
LIG_FHA_1	64	70	PF00498	0.818
LIG_FHA_1	725	731	PF00498	0.766
LIG_FHA_1	812	818	PF00498	0.512
LIG_FHA_2	154	160	PF00498	0.711
LIG_FHA_2	621	627	PF00498	0.765
LIG_FHA_2	704	710	PF00498	0.721
LIG_LIR_Apic_2	170	176	PF02991	0.745
LIG_LIR_Apic_2	470	474	PF02991	0.646
LIG_LIR_Gen_1	775	785	PF02991	0.527
LIG_LIR_Gen_1	833	843	PF02991	0.450
LIG_LIR_Nem_3	192	197	PF02991	0.783
LIG_LIR_Nem_3	775	781	PF02991	0.519
LIG_LIR_Nem_3	833	839	PF02991	0.364
LIG_PCNA_yPIPBox_3	195	207	PF02747	0.642
LIG_Pex14_2	165	169	PF04695	0.799
LIG_PTB_Apo_2	163	170	PF02174	0.685
LIG_Rb_LxCxE_1	732	754	PF01857	0.666
LIG_SH2_CRK	312	316	PF00017	0.570
LIG_SH2_CRK	778	782	PF00017	0.628
LIG_SH2_CRK	848	852	PF00017	0.411
LIG_SH2_NCK_1	456	460	PF00017	0.797
LIG_SH2_NCK_1	471	475	PF00017	0.609
LIG_SH2_NCK_1	761	765	PF00017	0.703
LIG_SH2_SRC	471	474	PF00017	0.783
LIG_SH2_SRC	750	753	PF00017	0.669
LIG_SH2_SRC	761	764	PF00017	0.580
LIG_SH2_SRC	94	97	PF00017	0.741
LIG_SH2_STAP1	197	201	PF00017	0.702
LIG_SH2_STAP1	456	460	PF00017	0.843
LIG_SH2_STAP1	778	782	PF00017	0.685
LIG_SH2_STAT3	197	200	PF00017	0.766
LIG_SH2_STAT5	322	325	PF00017	0.709
LIG_SH2_STAT5	745	748	PF00017	0.575
LIG_SH2_STAT5	816	819	PF00017	0.411
LIG_SH2_STAT5	836	839	PF00017	0.183
LIG_SH2_STAT5	896	899	PF00017	0.533
LIG_SH3_2	597	602	PF14604	0.765
LIG_SH3_3	261	267	PF00018	0.806
LIG_SH3_3	279	285	PF00018	0.527
LIG_SH3_3	33	39	PF00018	0.612
LIG_SH3_3	403	409	PF00018	0.766
LIG_SH3_3	564	570	PF00018	0.723
LIG_SH3_3	594	600	PF00018	0.772
LIG_SUMO_SIM_anti_2	680	686	PF11976	0.660
LIG_SUMO_SIM_par_1	522	529	PF11976	0.738
LIG_SUMO_SIM_par_1	579	584	PF11976	0.709
LIG_SUMO_SIM_par_1	660	666	PF11976	0.739
LIG_TRAF2_1	202	205	PF00917	0.632
LIG_TRFH_1	848	852	PF08558	0.286
LIG_TYR_ITIM	846	851	PF00017	0.411
LIG_WRC_WIRS_1	211	216	PF05994	0.730
LIG_WRC_WIRS_1	836	841	PF05994	0.411
LIG_WW_1	453	456	PF00397	0.721
MOD_CDK_SPxK_1	151	157	PF00069	0.646
MOD_CDK_SPxK_1	189	195	PF00069	0.598
MOD_CDK_SPxK_1	212	218	PF00069	0.681
MOD_CDK_SPxK_1	275	281	PF00069	0.706
MOD_CK1_1	123	129	PF00069	0.760
MOD_CK1_1	168	174	PF00069	0.703
MOD_CK1_1	19	25	PF00069	0.718
MOD_CK1_1	220	226	PF00069	0.703
MOD_CK1_1	350	356	PF00069	0.702
MOD_CK1_1	42	48	PF00069	0.741
MOD_CK1_1	421	427	PF00069	0.841
MOD_CK1_1	478	484	PF00069	0.763
MOD_CK1_1	533	539	PF00069	0.704
MOD_CK1_1	556	562	PF00069	0.716
MOD_CK1_1	618	624	PF00069	0.835
MOD_CK1_1	63	69	PF00069	0.834
MOD_CK1_1	653	659	PF00069	0.653
MOD_CK1_1	718	724	PF00069	0.660
MOD_CK1_1	857	863	PF00069	0.417
MOD_CK2_1	14	20	PF00069	0.592
MOD_CK2_1	168	174	PF00069	0.690
MOD_CK2_1	274	280	PF00069	0.658
MOD_CK2_1	289	295	PF00069	0.714
MOD_CK2_1	374	380	PF00069	0.820
MOD_CK2_1	620	626	PF00069	0.765
MOD_CK2_1	64	70	PF00069	0.774
MOD_CK2_1	751	757	PF00069	0.628
MOD_Cter_Amidation	512	515	PF01082	0.621
MOD_GlcNHglycan	108	111	PF01048	0.759
MOD_GlcNHglycan	116	119	PF01048	0.781
MOD_GlcNHglycan	136	139	PF01048	0.579
MOD_GlcNHglycan	145	148	PF01048	0.775
MOD_GlcNHglycan	170	173	PF01048	0.704
MOD_GlcNHglycan	186	189	PF01048	0.701
MOD_GlcNHglycan	20	24	PF01048	0.681
MOD_GlcNHglycan	221	225	PF01048	0.754
MOD_GlcNHglycan	251	254	PF01048	0.731
MOD_GlcNHglycan	255	258	PF01048	0.697
MOD_GlcNHglycan	354	357	PF01048	0.763
MOD_GlcNHglycan	376	379	PF01048	0.722
MOD_GlcNHglycan	420	423	PF01048	0.769
MOD_GlcNHglycan	44	47	PF01048	0.844
MOD_GlcNHglycan	477	480	PF01048	0.714
MOD_GlcNHglycan	532	535	PF01048	0.706
MOD_GlcNHglycan	561	564	PF01048	0.772
MOD_GlcNHglycan	604	607	PF01048	0.813
MOD_GlcNHglycan	620	623	PF01048	0.690
MOD_GlcNHglycan	637	640	PF01048	0.707
MOD_GlcNHglycan	653	656	PF01048	0.804
MOD_GlcNHglycan	665	668	PF01048	0.661
MOD_GlcNHglycan	700	703	PF01048	0.533
MOD_GlcNHglycan	8	11	PF01048	0.829
MOD_GlcNHglycan	825	828	PF01048	0.460
MOD_GlcNHglycan	855	859	PF01048	0.392
MOD_GSK3_1	116	123	PF00069	0.781
MOD_GSK3_1	143	150	PF00069	0.717
MOD_GSK3_1	168	175	PF00069	0.816
MOD_GSK3_1	189	196	PF00069	0.684
MOD_GSK3_1	206	213	PF00069	0.646
MOD_GSK3_1	219	226	PF00069	0.710
MOD_GSK3_1	249	256	PF00069	0.623
MOD_GSK3_1	296	303	PF00069	0.733
MOD_GSK3_1	370	377	PF00069	0.745
MOD_GSK3_1	408	415	PF00069	0.806
MOD_GSK3_1	418	425	PF00069	0.699
MOD_GSK3_1	430	437	PF00069	0.573
MOD_GSK3_1	448	455	PF00069	0.780
MOD_GSK3_1	474	481	PF00069	0.761
MOD_GSK3_1	530	537	PF00069	0.750
MOD_GSK3_1	541	548	PF00069	0.727
MOD_GSK3_1	549	556	PF00069	0.616
MOD_GSK3_1	56	63	PF00069	0.837
MOD_GSK3_1	614	621	PF00069	0.731
MOD_GSK3_1	694	701	PF00069	0.580
MOD_GSK3_1	715	722	PF00069	0.771
MOD_GSK3_1	725	732	PF00069	0.783
MOD_GSK3_1	769	776	PF00069	0.579
MOD_GSK3_1	831	838	PF00069	0.411
MOD_GSK3_1	84	91	PF00069	0.765
MOD_GSK3_1	856	863	PF00069	0.398
MOD_GSK3_1	890	897	PF00069	0.653
MOD_N-GLC_1	114	119	PF02516	0.841
MOD_N-GLC_1	165	170	PF02516	0.684
MOD_N-GLC_1	42	47	PF02516	0.805
MOD_N-GLC_1	63	68	PF02516	0.604
MOD_N-GLC_1	697	702	PF02516	0.643
MOD_NEK2_1	25	30	PF00069	0.844
MOD_NEK2_1	715	720	PF00069	0.662
MOD_NEK2_1	810	815	PF00069	0.405
MOD_NEK2_1	823	828	PF00069	0.424
MOD_NEK2_1	839	844	PF00069	0.411
MOD_NEK2_1	890	895	PF00069	0.641
MOD_NEK2_2	773	778	PF00069	0.633
MOD_PIKK_1	116	122	PF00454	0.729
MOD_PIKK_1	186	192	PF00454	0.674
MOD_PIKK_1	48	54	PF00454	0.835
MOD_PIKK_1	553	559	PF00454	0.744
MOD_PIKK_1	645	651	PF00454	0.795
MOD_PIKK_1	894	900	PF00454	0.696
MOD_PKA_1	719	725	PF00069	0.789
MOD_PKA_2	106	112	PF00069	0.715
MOD_PKA_2	280	286	PF00069	0.824
MOD_PKA_2	304	310	PF00069	0.812
MOD_PKA_2	422	428	PF00069	0.766
MOD_PKA_2	48	54	PF00069	0.835
MOD_PKA_2	650	656	PF00069	0.756
MOD_PKA_2	719	725	PF00069	0.789
MOD_PKA_2	78	84	PF00069	0.790
MOD_PKB_1	54	62	PF00069	0.794
MOD_Plk_1	165	171	PF00069	0.713
MOD_Plk_1	63	69	PF00069	0.644
MOD_Plk_2-3	757	763	PF00069	0.629
MOD_Plk_4	123	129	PF00069	0.815
MOD_Plk_4	244	250	PF00069	0.694
MOD_Plk_4	504	510	PF00069	0.642
MOD_Plk_4	64	70	PF00069	0.609
MOD_Plk_4	653	659	PF00069	0.621
MOD_Plk_4	725	731	PF00069	0.728
MOD_Plk_4	741	747	PF00069	0.564
MOD_Plk_4	773	779	PF00069	0.644
MOD_Plk_4	831	837	PF00069	0.411
MOD_Plk_4	84	90	PF00069	0.654
MOD_ProDKin_1	127	133	PF00069	0.706
MOD_ProDKin_1	14	20	PF00069	0.812
MOD_ProDKin_1	151	157	PF00069	0.699
MOD_ProDKin_1	172	178	PF00069	0.706
MOD_ProDKin_1	189	195	PF00069	0.690
MOD_ProDKin_1	212	218	PF00069	0.681
MOD_ProDKin_1	223	229	PF00069	0.730
MOD_ProDKin_1	27	33	PF00069	0.819
MOD_ProDKin_1	275	281	PF00069	0.706
MOD_ProDKin_1	297	303	PF00069	0.715
MOD_ProDKin_1	448	454	PF00069	0.596
MOD_ProDKin_1	57	63	PF00069	0.723
MOD_ProDKin_1	69	75	PF00069	0.756
MOD_ProDKin_1	751	757	PF00069	0.593
MOD_ProDKin_1	769	775	PF00069	0.577
MOD_ProDKin_1	88	94	PF00069	0.563
MOD_SUMO_rev_2	870	878	PF00179	0.450
TRG_DiLeu_BaEn_1	20	25	PF01217	0.776
TRG_DiLeu_BaLyEn_6	804	809	PF01217	0.286
TRG_DiLeu_BaLyEn_6	846	851	PF01217	0.450
TRG_ENDOCYTIC_2	242	245	PF00928	0.696
TRG_ENDOCYTIC_2	312	315	PF00928	0.571
TRG_ENDOCYTIC_2	778	781	PF00928	0.494
TRG_ENDOCYTIC_2	836	839	PF00928	0.411
TRG_ENDOCYTIC_2	848	851	PF00928	0.411
TRG_ER_diArg_1	149	152	PF00400	0.767
TRG_ER_diArg_1	231	233	PF00400	0.770
TRG_ER_diArg_1	315	317	PF00400	0.690
TRG_ER_diArg_1	514	516	PF00400	0.587
TRG_ER_diArg_1	572	574	PF00400	0.662
TRG_ER_diArg_1	640	642	PF00400	0.749
TRG_ER_diArg_1	77	80	PF00400	0.833
TRG_Pf-PMV_PEXEL_1	807	811	PF00026	0.411

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IA65	Leptomonas seymouri	45%	90%
A0A3S7X3A5	Leishmania donovani	90%	99%
A4HI89	Leishmania braziliensis	69%	100%
A4I5G8	Leishmania infantum	90%	85%
E9B0R6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%