Putative DNAJ domain protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNAJ domain protein, putative

Species:

Leishmania major

UniProt:

Q4Q7B5_LEIMA

TriTrypDb:

LmjF.30.1790 , LMJLV39_300024300 , LMJSD75_300024000

Length:

456

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q7B5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q7B5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	224	228	PF00656	0.529
CLV_C14_Caspase3-7	394	398	PF00656	0.548
CLV_C14_Caspase3-7	77	81	PF00656	0.242
CLV_NRD_NRD_1	24	26	PF00675	0.509
CLV_NRD_NRD_1	266	268	PF00675	0.423
CLV_NRD_NRD_1	376	378	PF00675	0.536
CLV_NRD_NRD_1	47	49	PF00675	0.327
CLV_PCSK_KEX2_1	199	201	PF00082	0.550
CLV_PCSK_KEX2_1	218	220	PF00082	0.537
CLV_PCSK_KEX2_1	24	26	PF00082	0.499
CLV_PCSK_KEX2_1	265	267	PF00082	0.581
CLV_PCSK_KEX2_1	99	101	PF00082	0.569
CLV_PCSK_PC1ET2_1	199	201	PF00082	0.516
CLV_PCSK_PC1ET2_1	218	220	PF00082	0.537
CLV_PCSK_PC1ET2_1	265	267	PF00082	0.581
CLV_PCSK_PC1ET2_1	99	101	PF00082	0.569
CLV_PCSK_PC7_1	262	268	PF00082	0.461
CLV_PCSK_SKI1_1	241	245	PF00082	0.475
CLV_PCSK_SKI1_1	252	256	PF00082	0.424
CLV_PCSK_SKI1_1	262	266	PF00082	0.379
CLV_PCSK_SKI1_1	385	389	PF00082	0.559
CLV_PCSK_SKI1_1	421	425	PF00082	0.552
CLV_PCSK_SKI1_1	49	53	PF00082	0.286
CLV_PCSK_SKI1_1	96	100	PF00082	0.592
CLV_Separin_Metazoa	364	368	PF03568	0.600
DEG_APCC_DBOX_1	24	32	PF00400	0.242
DEG_APCC_DBOX_1	301	309	PF00400	0.424
DEG_SPOP_SBC_1	234	238	PF00917	0.504
DOC_CYCLIN_RxL_1	250	259	PF00134	0.375
DOC_MAPK_gen_1	79	89	PF00069	0.242
DOC_PP4_FxxP_1	98	101	PF00568	0.518
DOC_USP7_MATH_1	103	107	PF00917	0.503
DOC_USP7_MATH_1	125	129	PF00917	0.513
DOC_USP7_MATH_1	179	183	PF00917	0.443
DOC_USP7_MATH_1	211	215	PF00917	0.634
DOC_USP7_MATH_1	228	232	PF00917	0.608
DOC_USP7_MATH_1	243	247	PF00917	0.531
DOC_USP7_MATH_1	278	282	PF00917	0.449
DOC_USP7_MATH_1	333	337	PF00917	0.480
DOC_USP7_MATH_1	354	358	PF00917	0.560
DOC_USP7_MATH_1	400	404	PF00917	0.737
DOC_USP7_MATH_1	423	427	PF00917	0.671
DOC_USP7_UBL2_3	195	199	PF12436	0.510
DOC_USP7_UBL2_3	374	378	PF12436	0.539
DOC_USP7_UBL2_3	92	96	PF12436	0.448
DOC_WW_Pin1_4	16	21	PF00397	0.508
DOC_WW_Pin1_4	319	324	PF00397	0.449
DOC_WW_Pin1_4	396	401	PF00397	0.574
DOC_WW_Pin1_4	403	408	PF00397	0.563
DOC_WW_Pin1_4	427	432	PF00397	0.542
DOC_WW_Pin1_4	6	11	PF00397	0.532
LIG_14-3-3_CanoR_1	200	204	PF00244	0.573
LIG_14-3-3_CanoR_1	24	29	PF00244	0.488
LIG_14-3-3_CanoR_1	279	283	PF00244	0.422
LIG_14-3-3_CanoR_1	302	306	PF00244	0.406
LIG_14-3-3_CanoR_1	377	387	PF00244	0.554
LIG_BRCT_BRCA1_1	334	338	PF00533	0.478
LIG_BRCT_BRCA1_1	356	360	PF00533	0.507
LIG_CtBP_PxDLS_1	311	315	PF00389	0.383
LIG_deltaCOP1_diTrp_1	285	290	PF00928	0.457
LIG_eIF4E_1	47	53	PF01652	0.303
LIG_FHA_1	175	181	PF00498	0.439
LIG_FHA_1	294	300	PF00498	0.363
LIG_FHA_1	345	351	PF00498	0.542
LIG_FHA_1	35	41	PF00498	0.291
LIG_FHA_2	268	274	PF00498	0.394
LIG_FHA_2	293	299	PF00498	0.369
LIG_FHA_2	37	43	PF00498	0.266
LIG_Integrin_isoDGR_2	383	385	PF01839	0.570
LIG_LIR_Apic_2	348	354	PF02991	0.552
LIG_LIR_Gen_1	26	34	PF02991	0.303
LIG_LIR_Nem_3	117	123	PF02991	0.561
LIG_LIR_Nem_3	148	152	PF02991	0.379
LIG_LIR_Nem_3	26	32	PF02991	0.318
LIG_LIR_Nem_3	285	290	PF02991	0.457
LIG_LIR_Nem_3	44	50	PF02991	0.199
LIG_MLH1_MIPbox_1	356	360	PF16413	0.507
LIG_SH2_CRK	112	116	PF00017	0.509
LIG_SH2_CRK	29	33	PF00017	0.267
LIG_SH2_CRK	47	51	PF00017	0.265
LIG_SH2_CRK	85	89	PF00017	0.406
LIG_SH2_GRB2like	359	362	PF00017	0.523
LIG_SH2_STAP1	112	116	PF00017	0.509
LIG_SH2_STAP1	121	125	PF00017	0.430
LIG_SH2_STAP1	85	89	PF00017	0.367
LIG_SH2_STAT5	359	362	PF00017	0.622
LIG_SH3_3	104	110	PF00018	0.490
LIG_SH3_3	305	311	PF00018	0.381
LIG_SH3_3	50	56	PF00018	0.343
LIG_TRAF2_1	322	325	PF00917	0.442
LIG_TRAF2_1	39	42	PF00917	0.303
MOD_CDK_SPK_2	6	11	PF00069	0.559
MOD_CK1_1	19	25	PF00069	0.574
MOD_CK1_1	202	208	PF00069	0.582
MOD_CK1_1	292	298	PF00069	0.370
MOD_CK1_1	344	350	PF00069	0.536
MOD_CK1_1	395	401	PF00069	0.803
MOD_CK1_1	402	408	PF00069	0.706
MOD_CK2_1	267	273	PF00069	0.396
MOD_CK2_1	292	298	PF00069	0.370
MOD_CK2_1	319	325	PF00069	0.590
MOD_CK2_1	36	42	PF00069	0.303
MOD_GlcNHglycan	162	165	PF01048	0.526
MOD_GlcNHglycan	214	217	PF01048	0.709
MOD_GlcNHglycan	330	333	PF01048	0.634
MOD_GlcNHglycan	394	397	PF01048	0.812
MOD_GlcNHglycan	421	424	PF01048	0.555
MOD_GlcNHglycan	425	428	PF01048	0.526
MOD_GlcNHglycan	6	9	PF01048	0.629
MOD_GSK3_1	174	181	PF00069	0.498
MOD_GSK3_1	19	26	PF00069	0.456
MOD_GSK3_1	198	205	PF00069	0.641
MOD_GSK3_1	2	9	PF00069	0.645
MOD_GSK3_1	288	295	PF00069	0.385
MOD_GSK3_1	32	39	PF00069	0.254
MOD_GSK3_1	328	335	PF00069	0.526
MOD_GSK3_1	341	348	PF00069	0.437
MOD_GSK3_1	392	399	PF00069	0.778
MOD_GSK3_1	402	409	PF00069	0.693
MOD_GSK3_1	419	426	PF00069	0.733
MOD_N-GLC_1	32	37	PF02516	0.303
MOD_NEK2_1	130	135	PF00069	0.439
MOD_NEK2_1	178	183	PF00069	0.546
MOD_NEK2_1	186	191	PF00069	0.481
MOD_NEK2_1	198	203	PF00069	0.585
MOD_NEK2_1	301	306	PF00069	0.401
MOD_NEK2_1	32	37	PF00069	0.303
MOD_NEK2_1	327	332	PF00069	0.492
MOD_NEK2_1	345	350	PF00069	0.469
MOD_NEK2_2	179	184	PF00069	0.388
MOD_NEK2_2	333	338	PF00069	0.481
MOD_NMyristoyl	1	7	PF02799	0.508
MOD_PIKK_1	400	406	PF00454	0.610
MOD_PIKK_1	74	80	PF00454	0.272
MOD_PKA_1	199	205	PF00069	0.567
MOD_PKA_1	24	30	PF00069	0.439
MOD_PKA_2	199	205	PF00069	0.603
MOD_PKA_2	221	227	PF00069	0.709
MOD_PKA_2	23	29	PF00069	0.472
MOD_PKA_2	278	284	PF00069	0.425
MOD_PKA_2	301	307	PF00069	0.408
MOD_PKA_2	328	334	PF00069	0.468
MOD_PKB_1	419	427	PF00069	0.553
MOD_Plk_4	103	109	PF00069	0.534
MOD_Plk_4	145	151	PF00069	0.406
MOD_Plk_4	24	30	PF00069	0.452
MOD_Plk_4	333	339	PF00069	0.516
MOD_Plk_4	346	352	PF00069	0.482
MOD_ProDKin_1	16	22	PF00069	0.502
MOD_ProDKin_1	319	325	PF00069	0.450
MOD_ProDKin_1	396	402	PF00069	0.575
MOD_ProDKin_1	403	409	PF00069	0.561
MOD_ProDKin_1	427	433	PF00069	0.544
MOD_ProDKin_1	6	12	PF00069	0.533
MOD_SUMO_for_1	271	274	PF00179	0.396
MOD_SUMO_for_1	453	456	PF00179	0.543
TRG_ENDOCYTIC_2	112	115	PF00928	0.502
TRG_ENDOCYTIC_2	159	162	PF00928	0.385
TRG_ENDOCYTIC_2	29	32	PF00928	0.265
TRG_ENDOCYTIC_2	47	50	PF00928	0.265
TRG_ENDOCYTIC_2	73	76	PF00928	0.265
TRG_ENDOCYTIC_2	85	88	PF00928	0.405
TRG_ER_diArg_1	23	25	PF00400	0.497
TRG_ER_diArg_1	266	268	PF00400	0.481

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P1T7	Trypanosomatidae	32%	100%
A4H933	Leishmania braziliensis	61%	78%