Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q799_LEIMA

TriTrypDb:

LmjF.30.1970 , LMJLV39_300026000 , LMJSD75_300025800

Length:

440

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q799

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q799

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	124	128	PF00656	0.700
CLV_NRD_NRD_1	144	146	PF00675	0.609
CLV_NRD_NRD_1	241	243	PF00675	0.510
CLV_NRD_NRD_1	344	346	PF00675	0.572
CLV_NRD_NRD_1	396	398	PF00675	0.515
CLV_PCSK_KEX2_1	144	146	PF00082	0.701
CLV_PCSK_KEX2_1	241	243	PF00082	0.520
CLV_PCSK_KEX2_1	288	290	PF00082	0.545
CLV_PCSK_KEX2_1	396	398	PF00082	0.419
CLV_PCSK_PC1ET2_1	288	290	PF00082	0.545
CLV_PCSK_SKI1_1	201	205	PF00082	0.609
CLV_PCSK_SKI1_1	24	28	PF00082	0.502
CLV_PCSK_SKI1_1	365	369	PF00082	0.684
CLV_PCSK_SKI1_1	423	427	PF00082	0.581
CLV_PCSK_SKI1_1	47	51	PF00082	0.527
CLV_PCSK_SKI1_1	64	68	PF00082	0.501
CLV_PCSK_SKI1_1	73	77	PF00082	0.429
DEG_APCC_DBOX_1	340	348	PF00400	0.599
DOC_CDC14_PxL_1	33	41	PF14671	0.515
DOC_CYCLIN_RxL_1	420	429	PF00134	0.688
DOC_MAPK_gen_1	226	233	PF00069	0.478
DOC_MAPK_gen_1	288	296	PF00069	0.445
DOC_MAPK_gen_1	396	403	PF00069	0.569
DOC_MAPK_MEF2A_6	226	233	PF00069	0.361
DOC_MAPK_MEF2A_6	376	384	PF00069	0.618
DOC_MAPK_MEF2A_6	396	403	PF00069	0.321
DOC_MAPK_MEF2A_6	423	432	PF00069	0.652
DOC_MAPK_RevD_3	229	242	PF00069	0.360
DOC_PP1_RVXF_1	22	28	PF00149	0.529
DOC_USP7_MATH_1	287	291	PF00917	0.469
DOC_USP7_MATH_1	81	85	PF00917	0.536
DOC_USP7_MATH_1	88	92	PF00917	0.592
DOC_WW_Pin1_4	3	8	PF00397	0.697
DOC_WW_Pin1_4	352	357	PF00397	0.633
LIG_14-3-3_CanoR_1	144	154	PF00244	0.679
LIG_14-3-3_CanoR_1	201	210	PF00244	0.556
LIG_14-3-3_CanoR_1	242	252	PF00244	0.596
LIG_14-3-3_CanoR_1	365	375	PF00244	0.697
LIG_14-3-3_CanoR_1	396	400	PF00244	0.582
LIG_14-3-3_CanoR_1	73	78	PF00244	0.548
LIG_14-3-3_CanoR_1	89	93	PF00244	0.467
LIG_BIR_II_1	1	5	PF00653	0.627
LIG_Clathr_ClatBox_1	154	158	PF01394	0.528
LIG_deltaCOP1_diTrp_1	209	214	PF00928	0.594
LIG_FHA_1	146	152	PF00498	0.483
LIG_FHA_1	202	208	PF00498	0.488
LIG_FHA_1	244	250	PF00498	0.607
LIG_FHA_1	276	282	PF00498	0.582
LIG_FHA_1	296	302	PF00498	0.520
LIG_FHA_1	349	355	PF00498	0.681
LIG_FHA_1	396	402	PF00498	0.614
LIG_FHA_1	72	78	PF00498	0.527
LIG_FHA_1	95	101	PF00498	0.538
LIG_FHA_2	107	113	PF00498	0.589
LIG_FHA_2	124	130	PF00498	0.592
LIG_FHA_2	422	428	PF00498	0.644
LIG_FHA_2	55	61	PF00498	0.608
LIG_LIR_Gen_1	45	53	PF02991	0.524
LIG_LIR_Gen_1	74	81	PF02991	0.512
LIG_LIR_LC3C_4	227	231	PF02991	0.360
LIG_LIR_Nem_3	45	51	PF02991	0.521
LIG_LIR_Nem_3	74	78	PF02991	0.468
LIG_SH2_CRK	48	52	PF00017	0.553
LIG_SH2_SRC	28	31	PF00017	0.631
LIG_SH2_SRC	299	302	PF00017	0.442
LIG_SH2_STAP1	28	32	PF00017	0.555
LIG_SH2_STAP1	292	296	PF00017	0.539
LIG_SH2_STAP1	95	99	PF00017	0.602
LIG_SH2_STAT3	303	306	PF00017	0.478
LIG_SUMO_SIM_anti_2	152	161	PF11976	0.573
LIG_SUMO_SIM_anti_2	326	331	PF11976	0.496
LIG_SUMO_SIM_par_1	152	161	PF11976	0.581
LIG_SUMO_SIM_par_1	265	270	PF11976	0.529
LIG_SUMO_SIM_par_1	350	355	PF11976	0.655
LIG_TRAF2_1	254	257	PF00917	0.498
LIG_TRAF2_1	91	94	PF00917	0.555
LIG_UBA3_1	39	47	PF00899	0.561
LIG_WRC_WIRS_1	50	55	PF05994	0.589
MOD_CDK_SPK_2	3	8	PF00069	0.697
MOD_CDK_SPxK_1	352	358	PF00069	0.682
MOD_CK1_1	147	153	PF00069	0.630
MOD_CK1_1	176	182	PF00069	0.533
MOD_CK1_1	2	8	PF00069	0.761
MOD_CK1_1	54	60	PF00069	0.552
MOD_CK1_1	9	15	PF00069	0.713
MOD_CK2_1	106	112	PF00069	0.525
MOD_CK2_1	123	129	PF00069	0.643
MOD_CK2_1	287	293	PF00069	0.499
MOD_CK2_1	387	393	PF00069	0.588
MOD_CK2_1	421	427	PF00069	0.679
MOD_CK2_1	49	55	PF00069	0.601
MOD_CK2_1	88	94	PF00069	0.505
MOD_GlcNHglycan	10	14	PF01048	0.584
MOD_GlcNHglycan	109	112	PF01048	0.592
MOD_GlcNHglycan	117	120	PF01048	0.621
MOD_GlcNHglycan	134	137	PF01048	0.664
MOD_GlcNHglycan	178	181	PF01048	0.599
MOD_GlcNHglycan	404	407	PF01048	0.683
MOD_GlcNHglycan	413	418	PF01048	0.633
MOD_GlcNHglycan	44	47	PF01048	0.507
MOD_GlcNHglycan	64	67	PF01048	0.310
MOD_GSK3_1	103	110	PF00069	0.627
MOD_GSK3_1	132	139	PF00069	0.683
MOD_GSK3_1	2	9	PF00069	0.763
MOD_GSK3_1	348	355	PF00069	0.547
MOD_GSK3_1	409	416	PF00069	0.628
MOD_GSK3_1	67	74	PF00069	0.563
MOD_N-GLC_1	132	137	PF02516	0.761
MOD_N-GLC_1	79	84	PF02516	0.603
MOD_NEK2_1	114	119	PF00069	0.627
MOD_NEK2_1	319	324	PF00069	0.593
MOD_NEK2_1	348	353	PF00069	0.478
MOD_NEK2_1	380	385	PF00069	0.590
MOD_NEK2_1	402	407	PF00069	0.638
MOD_NEK2_1	67	72	PF00069	0.596
MOD_PKA_1	144	150	PF00069	0.611
MOD_PKA_2	144	150	PF00069	0.611
MOD_PKA_2	387	393	PF00069	0.588
MOD_PKA_2	395	401	PF00069	0.564
MOD_PKA_2	88	94	PF00069	0.561
MOD_Plk_1	20	26	PF00069	0.574
MOD_Plk_1	267	273	PF00069	0.503
MOD_Plk_1	363	369	PF00069	0.680
MOD_Plk_2-3	415	421	PF00069	0.628
MOD_Plk_4	103	109	PF00069	0.647
MOD_Plk_4	35	41	PF00069	0.492
MOD_Plk_4	380	386	PF00069	0.494
MOD_Plk_4	81	87	PF00069	0.611
MOD_ProDKin_1	3	9	PF00069	0.695
MOD_ProDKin_1	352	358	PF00069	0.639
MOD_SUMO_for_1	281	284	PF00179	0.602
TRG_DiLeu_BaEn_1	225	230	PF01217	0.556
TRG_DiLeu_BaEn_1	315	320	PF01217	0.602
TRG_ENDOCYTIC_2	28	31	PF00928	0.589
TRG_ENDOCYTIC_2	48	51	PF00928	0.339
TRG_ER_diArg_1	143	145	PF00400	0.624
TRG_ER_diArg_1	289	292	PF00400	0.587
TRG_NLS_MonoExtC_3	287	293	PF00514	0.585
TRG_Pf-PMV_PEXEL_1	365	370	PF00026	0.669
TRG_Pf-PMV_PEXEL_1	423	427	PF00026	0.645

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDD9	Leptomonas seymouri	59%	100%
A0A1X0P1Q4	Trypanosomatidae	36%	95%
A0A3S5H7N1	Leishmania donovani	91%	100%
A0A3S5ISM8	Trypanosoma rangeli	34%	93%
A4HIC9	Leishmania braziliensis	73%	100%
A4I5M2	Leishmania infantum	91%	100%
E9B0W7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
V5B8X3	Trypanosoma cruzi	36%	93%