Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q796_LEIMA

TriTrypDb:

LmjF.30.1985 , LMJLV39_300026400 , LMJSD75_300026200

Length:

327

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q796

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q796

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	224	228	PF00656	0.791
CLV_C14_Caspase3-7	278	282	PF00656	0.690
CLV_NRD_NRD_1	15	17	PF00675	0.755
CLV_NRD_NRD_1	18	20	PF00675	0.720
CLV_PCSK_FUR_1	16	20	PF00082	0.762
CLV_PCSK_KEX2_1	15	17	PF00082	0.755
CLV_PCSK_KEX2_1	18	20	PF00082	0.720
CLV_PCSK_SKI1_1	18	22	PF00082	0.671
CLV_PCSK_SKI1_1	192	196	PF00082	0.681
DEG_Nend_UBRbox_3	1	3	PF02207	0.713
DEG_SPOP_SBC_1	286	290	PF00917	0.693
DOC_MAPK_gen_1	3	13	PF00069	0.720
DOC_MAPK_MEF2A_6	192	200	PF00069	0.681
DOC_PP1_RVXF_1	63	69	PF00149	0.675
DOC_PP2B_LxvP_1	98	101	PF13499	0.638
DOC_PP4_FxxP_1	283	286	PF00568	0.648
DOC_USP7_MATH_1	138	142	PF00917	0.681
DOC_USP7_MATH_1	218	222	PF00917	0.772
DOC_USP7_MATH_1	275	279	PF00917	0.686
DOC_USP7_MATH_1	310	314	PF00917	0.733
DOC_WW_Pin1_4	192	197	PF00397	0.574
DOC_WW_Pin1_4	55	60	PF00397	0.638
LIG_14-3-3_CanoR_1	146	151	PF00244	0.726
LIG_14-3-3_CanoR_1	235	242	PF00244	0.655
LIG_14-3-3_CanoR_1	274	280	PF00244	0.669
LIG_14-3-3_CanoR_1	298	302	PF00244	0.603
LIG_14-3-3_CanoR_1	309	315	PF00244	0.487
LIG_14-3-3_CanoR_1	6	13	PF00244	0.676
LIG_BRCT_BRCA1_1	289	293	PF00533	0.607
LIG_deltaCOP1_diTrp_1	281	287	PF00928	0.652
LIG_FHA_1	167	173	PF00498	0.675
LIG_FHA_1	193	199	PF00498	0.538
LIG_FHA_1	318	324	PF00498	0.681
LIG_FHA_1	6	12	PF00498	0.737
LIG_FHA_2	161	167	PF00498	0.611
LIG_FHA_2	209	215	PF00498	0.788
LIG_FHA_2	82	88	PF00498	0.840
LIG_Integrin_RGD_1	225	227	PF01839	0.794
LIG_LIR_Apic_2	281	286	PF02991	0.651
LIG_LIR_Gen_1	128	139	PF02991	0.583
LIG_LIR_Nem_3	128	134	PF02991	0.574
LIG_LIR_Nem_3	281	287	PF02991	0.430
LIG_NRBOX	129	135	PF00104	0.575
LIG_Pex14_2	283	287	PF04695	0.650
LIG_PTB_Apo_2	118	125	PF02174	0.603
LIG_SH2_NCK_1	279	283	PF00017	0.679
LIG_SH2_SRC	241	244	PF00017	0.687
LIG_SH2_STAT3	171	174	PF00017	0.547
LIG_SH2_STAT5	171	174	PF00017	0.644
LIG_SH2_STAT5	241	244	PF00017	0.657
LIG_SH2_STAT5	324	327	PF00017	0.652
LIG_SH3_3	108	114	PF00018	0.621
LIG_SH3_3	99	105	PF00018	0.782
MOD_CK1_1	142	148	PF00069	0.638
MOD_CK1_1	58	64	PF00069	0.779
MOD_CK2_1	146	152	PF00069	0.794
MOD_CK2_1	160	166	PF00069	0.579
MOD_CK2_1	218	224	PF00069	0.818
MOD_CK2_1	81	87	PF00069	0.717
MOD_DYRK1A_RPxSP_1	192	196	PF00069	0.644
MOD_GlcNHglycan	107	110	PF01048	0.630
MOD_GSK3_1	138	145	PF00069	0.664
MOD_GSK3_1	182	189	PF00069	0.572
MOD_GSK3_1	204	211	PF00069	0.758
MOD_GSK3_1	285	292	PF00069	0.590
MOD_GSK3_1	297	304	PF00069	0.538
MOD_N-GLC_1	120	125	PF02516	0.686
MOD_N-GLC_1	218	223	PF02516	0.624
MOD_NEK2_1	11	16	PF00069	0.753
MOD_NEK2_1	120	125	PF00069	0.610
MOD_NEK2_1	177	182	PF00069	0.620
MOD_NEK2_1	287	292	PF00069	0.630
MOD_PIKK_1	246	252	PF00454	0.533
MOD_PKA_2	145	151	PF00069	0.676
MOD_PKA_2	297	303	PF00069	0.554
MOD_PKA_2	317	323	PF00069	0.678
MOD_PKA_2	5	11	PF00069	0.773
MOD_Plk_1	120	126	PF00069	0.615
MOD_Plk_1	166	172	PF00069	0.665
MOD_Plk_1	186	192	PF00069	0.336
MOD_Plk_1	218	224	PF00069	0.771
MOD_Plk_1	266	272	PF00069	0.640
MOD_Plk_1	36	42	PF00069	0.777
MOD_Plk_4	114	120	PF00069	0.731
MOD_Plk_4	186	192	PF00069	0.560
MOD_Plk_4	38	44	PF00069	0.751
MOD_ProDKin_1	192	198	PF00069	0.571
MOD_ProDKin_1	55	61	PF00069	0.633
TRG_DiLeu_BaEn_2	126	132	PF01217	0.678
TRG_DiLeu_LyEn_5	26	31	PF01217	0.611
TRG_ER_diArg_1	15	18	PF00400	0.759
TRG_ER_diArg_1	271	274	PF00400	0.487

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P910	Leptomonas seymouri	38%	94%
A0A3S7X3F3	Leishmania donovani	87%	100%
A4I5M5	Leishmania infantum	87%	100%
E9B0X0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%