Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q792_LEIMA

TriTrypDb:

LmjF.30.2020 , LMJLV39_300026800 , LMJSD75_300026600

Length:

432

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q792

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q792

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	125	129	PF00656	0.648
CLV_C14_Caspase3-7	144	148	PF00656	0.504
CLV_NRD_NRD_1	160	162	PF00675	0.558
CLV_NRD_NRD_1	232	234	PF00675	0.660
CLV_NRD_NRD_1	358	360	PF00675	0.578
CLV_NRD_NRD_1	368	370	PF00675	0.551
CLV_NRD_NRD_1	373	375	PF00675	0.520
CLV_NRD_NRD_1	421	423	PF00675	0.561
CLV_PCSK_KEX2_1	234	236	PF00082	0.666
CLV_PCSK_KEX2_1	358	360	PF00082	0.578
CLV_PCSK_KEX2_1	372	374	PF00082	0.534
CLV_PCSK_KEX2_1	420	422	PF00082	0.736
CLV_PCSK_PC1ET2_1	234	236	PF00082	0.666
CLV_PCSK_PC7_1	369	375	PF00082	0.582
CLV_PCSK_SKI1_1	115	119	PF00082	0.574
CLV_PCSK_SKI1_1	421	425	PF00082	0.719
CLV_Separin_Metazoa	417	421	PF03568	0.567
DEG_APCC_DBOX_1	411	419	PF00400	0.663
DEG_APCC_DBOX_1	420	428	PF00400	0.695
DEG_Nend_UBRbox_1	1	4	PF02207	0.541
DEG_SCF_TRCP1_1	151	157	PF00400	0.565
DEG_SPOP_SBC_1	322	326	PF00917	0.567
DOC_ANK_TNKS_1	232	239	PF00023	0.590
DOC_CYCLIN_RxL_1	420	431	PF00134	0.712
DOC_CYCLIN_yCln2_LP_2	26	32	PF00134	0.581
DOC_MAPK_DCC_7	42	50	PF00069	0.583
DOC_MAPK_gen_1	358	364	PF00069	0.578
DOC_MAPK_MEF2A_6	42	50	PF00069	0.583
DOC_PP2B_LxvP_1	26	29	PF13499	0.650
DOC_PP2B_LxvP_1	43	46	PF13499	0.646
DOC_PP2B_PxIxI_1	7	13	PF00149	0.566
DOC_USP7_MATH_1	122	126	PF00917	0.606
DOC_USP7_MATH_1	299	303	PF00917	0.582
DOC_USP7_MATH_1	322	326	PF00917	0.654
DOC_USP7_MATH_1	72	76	PF00917	0.619
DOC_USP7_UBL2_3	331	335	PF12436	0.576
DOC_WW_Pin1_4	126	131	PF00397	0.611
DOC_WW_Pin1_4	164	169	PF00397	0.611
DOC_WW_Pin1_4	242	247	PF00397	0.541
DOC_WW_Pin1_4	310	315	PF00397	0.650
DOC_WW_Pin1_4	404	409	PF00397	0.615
DOC_WW_Pin1_4	76	81	PF00397	0.644
LIG_14-3-3_CanoR_1	115	121	PF00244	0.581
LIG_14-3-3_CanoR_1	247	253	PF00244	0.548
LIG_14-3-3_CanoR_1	306	312	PF00244	0.645
LIG_14-3-3_CanoR_1	353	362	PF00244	0.574
LIG_14-3-3_CanoR_1	372	381	PF00244	0.499
LIG_14-3-3_CanoR_1	94	99	PF00244	0.656
LIG_BRCT_BRCA1_1	151	155	PF00533	0.568
LIG_FHA_1	103	109	PF00498	0.575
LIG_FHA_1	116	122	PF00498	0.561
LIG_FHA_1	155	161	PF00498	0.629
LIG_FHA_1	183	189	PF00498	0.622
LIG_FHA_1	359	365	PF00498	0.580
LIG_FHA_2	121	127	PF00498	0.658
LIG_FHA_2	189	195	PF00498	0.646
LIG_FHA_2	282	288	PF00498	0.556
LIG_FHA_2	314	320	PF00498	0.560
LIG_LIR_Gen_1	105	111	PF02991	0.617
LIG_LIR_Gen_1	380	389	PF02991	0.520
LIG_LIR_Nem_3	105	110	PF02991	0.721
LIG_LIR_Nem_3	380	386	PF02991	0.543
LIG_SH2_CRK	16	20	PF00017	0.606
LIG_SH2_SRC	218	221	PF00017	0.652
LIG_SH2_STAP1	336	340	PF00017	0.563
LIG_SH2_STAT5	163	166	PF00017	0.551
LIG_SH3_3	105	111	PF00018	0.565
LIG_SH3_3	162	168	PF00018	0.616
LIG_SH3_3	341	347	PF00018	0.558
LIG_SH3_3	399	405	PF00018	0.580
LIG_SH3_3	408	414	PF00018	0.542
LIG_TRAF2_1	191	194	PF00917	0.647
MOD_CDK_SPK_2	242	247	PF00069	0.541
MOD_CK1_1	181	187	PF00069	0.617
MOD_CK1_1	242	248	PF00069	0.559
MOD_CK1_1	300	306	PF00069	0.598
MOD_CK1_1	310	316	PF00069	0.624
MOD_CK1_1	321	327	PF00069	0.664
MOD_CK1_1	339	345	PF00069	0.546
MOD_CK1_1	375	381	PF00069	0.558
MOD_CK1_1	390	396	PF00069	0.492
MOD_CK1_1	397	403	PF00069	0.552
MOD_CK1_1	75	81	PF00069	0.638
MOD_CK1_1	89	95	PF00069	0.547
MOD_CK2_1	120	126	PF00069	0.839
MOD_CK2_1	188	194	PF00069	0.641
MOD_CK2_1	313	319	PF00069	0.564
MOD_Cter_Amidation	370	373	PF01082	0.585
MOD_GlcNHglycan	151	154	PF01048	0.607
MOD_GlcNHglycan	180	183	PF01048	0.543
MOD_GlcNHglycan	241	244	PF01048	0.550
MOD_GlcNHglycan	292	295	PF01048	0.588
MOD_GlcNHglycan	296	302	PF01048	0.571
MOD_GlcNHglycan	319	323	PF01048	0.651
MOD_GlcNHglycan	355	358	PF01048	0.572
MOD_GlcNHglycan	396	399	PF01048	0.585
MOD_GlcNHglycan	70	73	PF01048	0.652
MOD_GlcNHglycan	81	84	PF01048	0.586
MOD_GlcNHglycan	88	91	PF01048	0.508
MOD_GSK3_1	116	123	PF00069	0.726
MOD_GSK3_1	178	185	PF00069	0.605
MOD_GSK3_1	273	280	PF00069	0.544
MOD_GSK3_1	313	320	PF00069	0.625
MOD_GSK3_1	321	328	PF00069	0.614
MOD_GSK3_1	387	394	PF00069	0.536
MOD_GSK3_1	64	71	PF00069	0.660
MOD_GSK3_1	72	79	PF00069	0.596
MOD_GSK3_1	85	92	PF00069	0.638
MOD_LATS_1	66	72	PF00433	0.588
MOD_NEK2_1	120	125	PF00069	0.708
MOD_NEK2_1	248	253	PF00069	0.548
MOD_NEK2_1	273	278	PF00069	0.544
MOD_NEK2_1	307	312	PF00069	0.705
MOD_NEK2_1	85	90	PF00069	0.683
MOD_PIKK_1	120	126	PF00454	0.650
MOD_PIKK_1	154	160	PF00454	0.631
MOD_PK_1	6	12	PF00069	0.530
MOD_PKA_1	358	364	PF00069	0.578
MOD_PKA_1	372	378	PF00069	0.522
MOD_PKA_2	281	287	PF00069	0.659
MOD_PKA_2	358	364	PF00069	0.578
MOD_PKA_2	372	378	PF00069	0.522
MOD_PKB_1	363	371	PF00069	0.583
MOD_PKB_1	372	380	PF00069	0.538
MOD_Plk_1	214	220	PF00069	0.608
MOD_Plk_1	336	342	PF00069	0.560
MOD_Plk_1	92	98	PF00069	0.646
MOD_Plk_2-3	214	220	PF00069	0.643
MOD_Plk_2-3	267	273	PF00069	0.549
MOD_Plk_4	116	122	PF00069	0.586
MOD_Plk_4	273	279	PF00069	0.588
MOD_Plk_4	387	393	PF00069	0.533
MOD_Plk_4	94	100	PF00069	0.814
MOD_ProDKin_1	126	132	PF00069	0.612
MOD_ProDKin_1	164	170	PF00069	0.611
MOD_ProDKin_1	242	248	PF00069	0.543
MOD_ProDKin_1	310	316	PF00069	0.649
MOD_ProDKin_1	404	410	PF00069	0.615
MOD_ProDKin_1	76	82	PF00069	0.646
MOD_SUMO_rev_2	189	199	PF00179	0.646
TRG_ENDOCYTIC_2	16	19	PF00928	0.606
TRG_ER_diArg_1	232	235	PF00400	0.663
TRG_ER_diArg_1	362	365	PF00400	0.582
TRG_ER_diArg_1	372	374	PF00400	0.548
TRG_ER_diArg_1	419	422	PF00400	0.565
TRG_NLS_Bipartite_1	358	373	PF00514	0.581
TRG_NLS_MonoExtC_3	368	373	PF00514	0.585
TRG_Pf-PMV_PEXEL_1	338	343	PF00026	0.559
TRG_Pf-PMV_PEXEL_1	350	354	PF00026	0.539

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IEZ3	Leishmania donovani	79%	100%
A4I5M9	Leishmania infantum	78%	100%