Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q787_LEIMA

TriTrypDb:

LmjF.30.2065 , LMJLV39_300027300 , LMJSD75_300027200

Length:

313

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q787

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q787

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	12	14	PF00675	0.507
CLV_NRD_NRD_1	125	127	PF00675	0.690
CLV_NRD_NRD_1	137	139	PF00675	0.597
CLV_NRD_NRD_1	154	156	PF00675	0.688
CLV_NRD_NRD_1	207	209	PF00675	0.550
CLV_NRD_NRD_1	226	228	PF00675	0.439
CLV_NRD_NRD_1	292	294	PF00675	0.571
CLV_NRD_NRD_1	300	302	PF00675	0.491
CLV_NRD_NRD_1	70	72	PF00675	0.560
CLV_NRD_NRD_1	95	97	PF00675	0.600
CLV_PCSK_FUR_1	123	127	PF00082	0.690
CLV_PCSK_FUR_1	152	156	PF00082	0.588
CLV_PCSK_FUR_1	68	72	PF00082	0.627
CLV_PCSK_KEX2_1	12	14	PF00082	0.496
CLV_PCSK_KEX2_1	125	127	PF00082	0.634
CLV_PCSK_KEX2_1	137	139	PF00082	0.578
CLV_PCSK_KEX2_1	154	156	PF00082	0.688
CLV_PCSK_KEX2_1	207	209	PF00082	0.528
CLV_PCSK_KEX2_1	226	228	PF00082	0.440
CLV_PCSK_KEX2_1	292	294	PF00082	0.592
CLV_PCSK_KEX2_1	300	302	PF00082	0.491
CLV_PCSK_KEX2_1	70	72	PF00082	0.560
CLV_PCSK_KEX2_1	95	97	PF00082	0.599
CLV_PCSK_PC7_1	133	139	PF00082	0.622
CLV_PCSK_SKI1_1	126	130	PF00082	0.613
DEG_Nend_UBRbox_1	1	4	PF02207	0.619
DEG_SCF_FBW7_1	111	116	PF00400	0.704
DEG_SPOP_SBC_1	132	136	PF00917	0.510
DOC_CKS1_1	127	132	PF01111	0.632
DOC_CKS1_1	281	286	PF01111	0.756
DOC_MAPK_DCC_7	196	204	PF00069	0.571
DOC_MAPK_MEF2A_6	196	204	PF00069	0.571
DOC_MAPK_MEF2A_6	244	253	PF00069	0.629
DOC_USP7_MATH_1	113	117	PF00917	0.622
DOC_USP7_MATH_1	131	135	PF00917	0.477
DOC_USP7_MATH_1	15	19	PF00917	0.508
DOC_USP7_MATH_1	30	34	PF00917	0.541
DOC_USP7_UBL2_3	192	196	PF12436	0.572
DOC_USP7_UBL2_3	205	209	PF12436	0.454
DOC_WW_Pin1_4	109	114	PF00397	0.654
DOC_WW_Pin1_4	126	131	PF00397	0.472
DOC_WW_Pin1_4	255	260	PF00397	0.619
DOC_WW_Pin1_4	280	285	PF00397	0.691
DOC_WW_Pin1_4	294	299	PF00397	0.589
DOC_WW_Pin1_4	62	67	PF00397	0.644
DOC_WW_Pin1_4	96	101	PF00397	0.628
LIG_14-3-3_CanoR_1	114	122	PF00244	0.662
LIG_14-3-3_CanoR_1	133	141	PF00244	0.634
LIG_14-3-3_CanoR_1	162	167	PF00244	0.629
LIG_14-3-3_CanoR_1	173	183	PF00244	0.525
LIG_14-3-3_CanoR_1	300	304	PF00244	0.582
LIG_BRCT_BRCA1_1	167	171	PF00533	0.571
LIG_deltaCOP1_diTrp_1	243	248	PF00928	0.606
LIG_FHA_1	300	306	PF00498	0.606
LIG_FHA_2	2	8	PF00498	0.654
LIG_LIR_Gen_1	18	24	PF02991	0.689
LIG_LIR_Gen_1	243	253	PF02991	0.625
LIG_LIR_Gen_1	302	311	PF02991	0.468
LIG_LIR_Nem_3	18	23	PF02991	0.688
LIG_LIR_Nem_3	243	249	PF02991	0.609
LIG_LIR_Nem_3	302	306	PF02991	0.461
LIG_PCNA_yPIPBox_3	173	187	PF02747	0.598
LIG_SH2_PTP2	127	130	PF00017	0.588
LIG_SH2_STAP1	55	59	PF00017	0.595
LIG_SH2_STAT5	127	130	PF00017	0.656
LIG_SH3_1	278	284	PF00018	0.563
LIG_SH3_3	116	122	PF00018	0.691
LIG_SH3_3	125	131	PF00018	0.666
LIG_SH3_3	184	190	PF00018	0.540
LIG_SH3_3	191	197	PF00018	0.496
LIG_SH3_3	268	274	PF00018	0.682
LIG_SH3_3	278	284	PF00018	0.690
LIG_SH3_4	192	199	PF00018	0.643
LIG_SH3_4	205	212	PF00018	0.661
LIG_SUMO_SIM_par_1	273	279	PF11976	0.586
MOD_CDK_SPK_2	109	114	PF00069	0.663
MOD_CDK_SPxK_1	294	300	PF00069	0.541
MOD_CDK_SPxK_1	62	68	PF00069	0.703
MOD_CDK_SPxxK_3	126	133	PF00069	0.635
MOD_CDK_SPxxK_3	280	287	PF00069	0.564
MOD_CDK_SPxxK_3	294	301	PF00069	0.505
MOD_CK1_1	165	171	PF00069	0.657
MOD_CK1_1	172	178	PF00069	0.587
MOD_CK1_1	28	34	PF00069	0.716
MOD_CK2_1	1	7	PF00069	0.663
MOD_Cter_Amidation	290	293	PF01082	0.609
MOD_Cter_Amidation	68	71	PF01082	0.585
MOD_GlcNHglycan	149	152	PF01048	0.646
MOD_GlcNHglycan	220	223	PF01048	0.562
MOD_GlcNHglycan	239	242	PF01048	0.392
MOD_GSK3_1	109	116	PF00069	0.581
MOD_GSK3_1	165	172	PF00069	0.613
MOD_GSK3_1	43	50	PF00069	0.512
MOD_N-GLC_1	264	269	PF02516	0.542
MOD_NEK2_1	1	6	PF00069	0.616
MOD_NEK2_2	15	20	PF00069	0.486
MOD_PIKK_1	165	171	PF00454	0.594
MOD_PK_1	162	168	PF00069	0.710
MOD_PKA_1	95	101	PF00069	0.517
MOD_PKA_2	113	119	PF00069	0.596
MOD_PKA_2	132	138	PF00069	0.388
MOD_PKA_2	172	178	PF00069	0.614
MOD_PKA_2	25	31	PF00069	0.527
MOD_PKA_2	299	305	PF00069	0.546
MOD_PKA_2	88	94	PF00069	0.740
MOD_PKA_2	95	101	PF00069	0.785
MOD_Plk_1	264	270	PF00069	0.578
MOD_Plk_1	50	56	PF00069	0.508
MOD_Plk_4	15	21	PF00069	0.468
MOD_Plk_4	182	188	PF00069	0.661
MOD_Plk_4	50	56	PF00069	0.640
MOD_ProDKin_1	109	115	PF00069	0.654
MOD_ProDKin_1	126	132	PF00069	0.472
MOD_ProDKin_1	255	261	PF00069	0.620
MOD_ProDKin_1	280	286	PF00069	0.696
MOD_ProDKin_1	294	300	PF00069	0.587
MOD_ProDKin_1	62	68	PF00069	0.643
MOD_ProDKin_1	96	102	PF00069	0.628
TRG_ER_diArg_1	122	125	PF00400	0.697
TRG_ER_diArg_1	137	139	PF00400	0.557
TRG_ER_diArg_1	152	155	PF00400	0.654
TRG_ER_diArg_1	206	208	PF00400	0.572
TRG_ER_diArg_1	292	294	PF00400	0.577
TRG_ER_diArg_1	299	301	PF00400	0.517
TRG_ER_diArg_1	67	70	PF00400	0.665
TRG_ER_diArg_1	94	96	PF00400	0.640
TRG_Pf-PMV_PEXEL_1	35	40	PF00026	0.455
TRG_Pf-PMV_PEXEL_1	6	10	PF00026	0.610

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P913	Leptomonas seymouri	61%	100%
A0A1X0P1U3	Trypanosomatidae	30%	100%
A0A3Q8IFW1	Leishmania donovani	93%	100%
A0A422P3E4	Trypanosoma rangeli	33%	100%
A4HID8	Leishmania braziliensis	76%	99%
A4I5N5	Leishmania infantum	93%	100%
C9ZR04	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
E9B0X9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
V5BYT6	Trypanosoma cruzi	33%	99%