LeishMANIAdb
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NFACT-R_1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
NFACT-R_1 domain-containing protein
Gene product:
Domain of unknown function (DUF814), putative
Species:
Leishmania major
UniProt:
Q4Q786_LEIMA
TriTrypDb:
LmjF.30.2070 , LMJLV39_300027400 , LMJSD75_300027300
Length:
208

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q786
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q786

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 115 117 PF00675 0.391
CLV_NRD_NRD_1 143 145 PF00675 0.586
CLV_NRD_NRD_1 155 157 PF00675 0.471
CLV_PCSK_KEX2_1 115 117 PF00082 0.391
CLV_PCSK_KEX2_1 155 157 PF00082 0.471
CLV_PCSK_KEX2_1 177 179 PF00082 0.527
CLV_PCSK_PC1ET2_1 177 179 PF00082 0.527
CLV_PCSK_PC7_1 173 179 PF00082 0.608
CLV_PCSK_SKI1_1 125 129 PF00082 0.527
DEG_APCC_DBOX_1 124 132 PF00400 0.541
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IME9 Leptomonas seymouri 85% 100%
A0A0S4JLK1 Bodo saltans 70% 100%
A0A1X0P1Z6 Trypanosomatidae 65% 100%
A0A3S7X3G6 Leishmania donovani 98% 100%
A0A422P3G2 Trypanosoma rangeli 65% 100%
A4HID9 Leishmania braziliensis 91% 100%
A4I5N6 Leishmania infantum 98% 100%
C9ZR05 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 68% 100%
E9B0Y0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
P40206 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 40% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS