LeishMANIAdb
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Phospholipid-transporting ATPase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Phospholipid-transporting ATPase
Gene product:
phospholipid-translocating P-type ATPase (flippase), putative
Species:
Leishmania major
UniProt:
Q4Q767_LEIMA
TriTrypDb:
LmjF.30.2260 * , LMJLV39_300029800 * , LMJSD75_300029500 *
Length:
1279

Annotations

LeishMANIAdb annotations

Eukaryotic P-ATPase protein, its closest animal relatives (ATP11A) are involved in phospholipid transport.. Localization: Endosomal (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 17
NetGPI no yes: 0, no: 17
Cellular components
Term Name Level Count
GO:0005886 plasma membrane 3 2
GO:0016020 membrane 2 18
GO:0110165 cellular anatomical entity 1 18

Expansion

Sequence features

Q4Q767
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q767

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 13
GO:0006869 lipid transport 5 13
GO:0009987 cellular process 1 2
GO:0015748 organophosphate ester transport 5 13
GO:0015914 phospholipid transport 6 13
GO:0016043 cellular component organization 3 2
GO:0034204 lipid translocation 4 2
GO:0045332 phospholipid translocation 5 2
GO:0051179 localization 1 13
GO:0051234 establishment of localization 2 13
GO:0061024 membrane organization 4 2
GO:0065007 biological regulation 1 2
GO:0065008 regulation of biological quality 2 2
GO:0071702 organic substance transport 4 13
GO:0071840 cellular component organization or biogenesis 2 2
GO:0097035 regulation of membrane lipid distribution 3 2
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 18
GO:0000287 magnesium ion binding 5 13
GO:0003824 catalytic activity 1 17
GO:0005215 transporter activity 1 17
GO:0005319 lipid transporter activity 2 17
GO:0005488 binding 1 18
GO:0005524 ATP binding 5 17
GO:0016462 pyrophosphatase activity 5 17
GO:0016787 hydrolase activity 2 17
GO:0016817 hydrolase activity, acting on acid anhydrides 3 17
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 17
GO:0016887 ATP hydrolysis activity 7 17
GO:0017076 purine nucleotide binding 4 17
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 17
GO:0030554 adenyl nucleotide binding 5 17
GO:0032553 ribonucleotide binding 3 17
GO:0032555 purine ribonucleotide binding 4 17
GO:0032559 adenyl ribonucleotide binding 5 17
GO:0035639 purine ribonucleoside triphosphate binding 4 17
GO:0036094 small molecule binding 2 18
GO:0043167 ion binding 2 17
GO:0043168 anion binding 3 17
GO:0043169 cation binding 3 13
GO:0046872 metal ion binding 4 13
GO:0097159 organic cyclic compound binding 2 18
GO:0097367 carbohydrate derivative binding 2 17
GO:0140303 intramembrane lipid transporter activity 3 17
GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2 17
GO:0140657 ATP-dependent activity 1 17
GO:1901265 nucleoside phosphate binding 3 18
GO:1901363 heterocyclic compound binding 2 18
GO:0004518 nuclease activity 4 1
GO:0004519 endonuclease activity 5 1
GO:0004521 RNA endonuclease activity 5 1
GO:0004526 ribonuclease P activity 6 1
GO:0004540 RNA nuclease activity 4 1
GO:0004549 tRNA-specific ribonuclease activity 5 1
GO:0016788 hydrolase activity, acting on ester bonds 3 1
GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 6 1
GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6 1
GO:0140098 catalytic activity, acting on RNA 3 1
GO:0140101 catalytic activity, acting on a tRNA 4 1
GO:0140640 catalytic activity, acting on a nucleic acid 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 151 155 PF00656 0.478
CLV_C14_Caspase3-7 597 601 PF00656 0.368
CLV_C14_Caspase3-7 836 840 PF00656 0.691
CLV_C14_Caspase3-7 939 943 PF00656 0.450
CLV_NRD_NRD_1 101 103 PF00675 0.306
CLV_NRD_NRD_1 1180 1182 PF00675 0.506
CLV_NRD_NRD_1 1227 1229 PF00675 0.361
CLV_NRD_NRD_1 1235 1237 PF00675 0.368
CLV_NRD_NRD_1 1261 1263 PF00675 0.498
CLV_NRD_NRD_1 177 179 PF00675 0.405
CLV_NRD_NRD_1 2 4 PF00675 0.327
CLV_NRD_NRD_1 279 281 PF00675 0.315
CLV_NRD_NRD_1 391 393 PF00675 0.370
CLV_NRD_NRD_1 472 474 PF00675 0.393
CLV_NRD_NRD_1 518 520 PF00675 0.289
CLV_NRD_NRD_1 538 540 PF00675 0.257
CLV_NRD_NRD_1 589 591 PF00675 0.273
CLV_NRD_NRD_1 650 652 PF00675 0.327
CLV_PCSK_FUR_1 389 393 PF00082 0.349
CLV_PCSK_FUR_1 536 540 PF00082 0.322
CLV_PCSK_KEX2_1 101 103 PF00082 0.284
CLV_PCSK_KEX2_1 1227 1229 PF00082 0.342
CLV_PCSK_KEX2_1 1235 1237 PF00082 0.358
CLV_PCSK_KEX2_1 1239 1241 PF00082 0.353
CLV_PCSK_KEX2_1 1261 1263 PF00082 0.498
CLV_PCSK_KEX2_1 177 179 PF00082 0.405
CLV_PCSK_KEX2_1 2 4 PF00082 0.303
CLV_PCSK_KEX2_1 279 281 PF00082 0.377
CLV_PCSK_KEX2_1 391 393 PF00082 0.370
CLV_PCSK_KEX2_1 472 474 PF00082 0.366
CLV_PCSK_KEX2_1 538 540 PF00082 0.249
CLV_PCSK_KEX2_1 589 591 PF00082 0.230
CLV_PCSK_KEX2_1 650 652 PF00082 0.363
CLV_PCSK_KEX2_1 88 90 PF00082 0.314
CLV_PCSK_PC1ET2_1 1239 1241 PF00082 0.431
CLV_PCSK_PC1ET2_1 279 281 PF00082 0.343
CLV_PCSK_PC1ET2_1 88 90 PF00082 0.322
CLV_PCSK_PC7_1 1235 1241 PF00082 0.455
CLV_PCSK_SKI1_1 1006 1010 PF00082 0.303
CLV_PCSK_SKI1_1 101 105 PF00082 0.272
CLV_PCSK_SKI1_1 1058 1062 PF00082 0.229
CLV_PCSK_SKI1_1 1089 1093 PF00082 0.294
CLV_PCSK_SKI1_1 1218 1222 PF00082 0.340
CLV_PCSK_SKI1_1 1230 1234 PF00082 0.353
CLV_PCSK_SKI1_1 346 350 PF00082 0.255
CLV_PCSK_SKI1_1 532 536 PF00082 0.241
CLV_PCSK_SKI1_1 654 658 PF00082 0.282
CLV_PCSK_SKI1_1 661 665 PF00082 0.295
CLV_PCSK_SKI1_1 982 986 PF00082 0.226
DEG_APCC_DBOX_1 1088 1096 PF00400 0.398
DEG_Nend_UBRbox_1 1 4 PF02207 0.508
DEG_ODPH_VHL_1 59 71 PF01847 0.275
DEG_SCF_TRCP1_1 1113 1119 PF00400 0.277
DEG_SPOP_SBC_1 1162 1166 PF00917 0.386
DOC_ANK_TNKS_1 1102 1109 PF00023 0.148
DOC_CKS1_1 1212 1217 PF01111 0.484
DOC_CYCLIN_RxL_1 1227 1237 PF00134 0.599
DOC_CYCLIN_yClb5_NLxxxL_5 1146 1155 PF00134 0.508
DOC_CYCLIN_yCln2_LP_2 1155 1161 PF00134 0.386
DOC_MAPK_gen_1 1069 1077 PF00069 0.422
DOC_MAPK_gen_1 1227 1233 PF00069 0.628
DOC_MAPK_gen_1 1235 1246 PF00069 0.619
DOC_MAPK_gen_1 160 167 PF00069 0.589
DOC_MAPK_gen_1 472 480 PF00069 0.573
DOC_MAPK_gen_1 519 525 PF00069 0.457
DOC_MAPK_gen_1 589 596 PF00069 0.443
DOC_MAPK_gen_1 650 658 PF00069 0.462
DOC_MAPK_gen_1 784 793 PF00069 0.617
DOC_MAPK_gen_1 928 938 PF00069 0.466
DOC_MAPK_JIP1_4 41 47 PF00069 0.430
DOC_MAPK_MEF2A_6 589 596 PF00069 0.448
DOC_MAPK_MEF2A_6 665 672 PF00069 0.593
DOC_MAPK_MEF2A_6 752 760 PF00069 0.616
DOC_MAPK_MEF2A_6 931 940 PF00069 0.450
DOC_PP1_RVXF_1 106 112 PF00149 0.454
DOC_PP1_RVXF_1 370 377 PF00149 0.543
DOC_PP1_RVXF_1 601 607 PF00149 0.517
DOC_PP1_RVXF_1 829 836 PF00149 0.663
DOC_PP1_RVXF_1 980 987 PF00149 0.410
DOC_PP2B_LxvP_1 1155 1158 PF13499 0.386
DOC_PP2B_LxvP_1 1199 1202 PF13499 0.294
DOC_PP2B_LxvP_1 329 332 PF13499 0.342
DOC_PP2B_LxvP_1 798 801 PF13499 0.646
DOC_PP4_FxxP_1 1212 1215 PF00568 0.607
DOC_PP4_FxxP_1 39 42 PF00568 0.401
DOC_USP7_MATH_1 110 114 PF00917 0.474
DOC_USP7_MATH_1 230 234 PF00917 0.656
DOC_USP7_MATH_1 336 340 PF00917 0.359
DOC_USP7_MATH_1 393 397 PF00917 0.607
DOC_USP7_MATH_1 489 493 PF00917 0.690
DOC_USP7_MATH_1 584 588 PF00917 0.408
DOC_USP7_MATH_1 623 627 PF00917 0.621
DOC_USP7_MATH_1 676 680 PF00917 0.637
DOC_USP7_MATH_1 814 818 PF00917 0.639
DOC_USP7_MATH_1 837 841 PF00917 0.640
DOC_USP7_MATH_1 854 858 PF00917 0.647
DOC_USP7_MATH_1 870 874 PF00917 0.712
DOC_USP7_MATH_1 971 975 PF00917 0.438
DOC_USP7_UBL2_3 281 285 PF12436 0.564
DOC_WW_Pin1_4 1144 1149 PF00397 0.517
DOC_WW_Pin1_4 1168 1173 PF00397 0.282
DOC_WW_Pin1_4 1211 1216 PF00397 0.486
DOC_WW_Pin1_4 1249 1254 PF00397 0.628
DOC_WW_Pin1_4 505 510 PF00397 0.445
DOC_WW_Pin1_4 916 921 PF00397 0.487
LIG_14-3-3_CanoR_1 1181 1185 PF00244 0.305
LIG_14-3-3_CanoR_1 1261 1267 PF00244 0.664
LIG_14-3-3_CanoR_1 24 28 PF00244 0.413
LIG_14-3-3_CanoR_1 241 251 PF00244 0.564
LIG_14-3-3_CanoR_1 295 302 PF00244 0.517
LIG_14-3-3_CanoR_1 589 593 PF00244 0.442
LIG_14-3-3_CanoR_1 644 648 PF00244 0.499
LIG_14-3-3_CanoR_1 651 657 PF00244 0.480
LIG_14-3-3_CanoR_1 752 760 PF00244 0.498
LIG_14-3-3_CanoR_1 807 816 PF00244 0.637
LIG_APCC_ABBA_1 635 640 PF00400 0.502
LIG_BRCT_BRCA1_1 357 361 PF00533 0.265
LIG_CtBP_PxDLS_1 522 528 PF00389 0.517
LIG_EH1_1 1085 1093 PF00400 0.161
LIG_EVH1_1 798 802 PF00568 0.672
LIG_FHA_1 1121 1127 PF00498 0.232
LIG_FHA_1 1184 1190 PF00498 0.268
LIG_FHA_1 1206 1212 PF00498 0.363
LIG_FHA_1 141 147 PF00498 0.488
LIG_FHA_1 148 154 PF00498 0.472
LIG_FHA_1 15 21 PF00498 0.533
LIG_FHA_1 177 183 PF00498 0.590
LIG_FHA_1 350 356 PF00498 0.289
LIG_FHA_1 421 427 PF00498 0.445
LIG_FHA_1 463 469 PF00498 0.622
LIG_FHA_1 481 487 PF00498 0.524
LIG_FHA_1 574 580 PF00498 0.476
LIG_FHA_1 589 595 PF00498 0.381
LIG_FHA_1 653 659 PF00498 0.476
LIG_FHA_1 72 78 PF00498 0.259
LIG_FHA_1 828 834 PF00498 0.650
LIG_FHA_1 935 941 PF00498 0.451
LIG_FHA_2 1232 1238 PF00498 0.507
LIG_FHA_2 1250 1256 PF00498 0.558
LIG_FHA_2 166 172 PF00498 0.610
LIG_FHA_2 267 273 PF00498 0.433
LIG_FHA_2 453 459 PF00498 0.665
LIG_FHA_2 662 668 PF00498 0.505
LIG_FHA_2 704 710 PF00498 0.474
LIG_FHA_2 717 723 PF00498 0.467
LIG_GBD_Chelix_1 724 732 PF00786 0.214
LIG_HCF-1_HBM_1 93 96 PF13415 0.500
LIG_IBAR_NPY_1 1064 1066 PF08397 0.420
LIG_LIR_Apic_2 1210 1215 PF02991 0.544
LIG_LIR_Apic_2 324 330 PF02991 0.412
LIG_LIR_Apic_2 37 42 PF02991 0.401
LIG_LIR_Gen_1 1011 1020 PF02991 0.272
LIG_LIR_Gen_1 1028 1037 PF02991 0.208
LIG_LIR_Gen_1 1125 1136 PF02991 0.270
LIG_LIR_Gen_1 1203 1212 PF02991 0.161
LIG_LIR_Gen_1 164 175 PF02991 0.516
LIG_LIR_Gen_1 976 986 PF02991 0.418
LIG_LIR_LC3C_4 1196 1201 PF02991 0.400
LIG_LIR_LC3C_4 17 21 PF02991 0.407
LIG_LIR_Nem_3 1011 1015 PF02991 0.273
LIG_LIR_Nem_3 1028 1033 PF02991 0.209
LIG_LIR_Nem_3 1036 1041 PF02991 0.262
LIG_LIR_Nem_3 1047 1052 PF02991 0.317
LIG_LIR_Nem_3 1081 1086 PF02991 0.427
LIG_LIR_Nem_3 1125 1131 PF02991 0.285
LIG_LIR_Nem_3 1173 1179 PF02991 0.236
LIG_LIR_Nem_3 1203 1209 PF02991 0.362
LIG_LIR_Nem_3 164 170 PF02991 0.630
LIG_LIR_Nem_3 358 362 PF02991 0.337
LIG_LIR_Nem_3 82 87 PF02991 0.519
LIG_LIR_Nem_3 976 981 PF02991 0.418
LIG_NRBOX 1150 1156 PF00104 0.396
LIG_NRBOX 980 986 PF00104 0.421
LIG_PCNA_yPIPBox_3 307 318 PF02747 0.398
LIG_PCNA_yPIPBox_3 91 104 PF02747 0.576
LIG_PDZ_Class_3 1274 1279 PF00595 0.624
LIG_Pex14_1 1038 1042 PF04695 0.287
LIG_Pex14_1 1245 1249 PF04695 0.654
LIG_Pex14_2 1029 1033 PF04695 0.207
LIG_Pex14_2 1082 1086 PF04695 0.319
LIG_PTB_Apo_2 1036 1043 PF02174 0.246
LIG_PTB_Apo_2 19 26 PF02174 0.418
LIG_PTB_Phospho_1 1036 1042 PF10480 0.275
LIG_PTB_Phospho_1 19 25 PF10480 0.418
LIG_RPA_C_Fungi 109 121 PF08784 0.292
LIG_SH2_CRK 1017 1021 PF00017 0.349
LIG_SH2_CRK 1042 1046 PF00017 0.267
LIG_SH2_CRK 1128 1132 PF00017 0.286
LIG_SH2_CRK 1264 1268 PF00017 0.698
LIG_SH2_NCK_1 1017 1021 PF00017 0.352
LIG_SH2_NCK_1 1042 1046 PF00017 0.278
LIG_SH2_NCK_1 1264 1268 PF00017 0.407
LIG_SH2_SRC 1111 1114 PF00017 0.386
LIG_SH2_SRC 1161 1164 PF00017 0.398
LIG_SH2_SRC 84 87 PF00017 0.339
LIG_SH2_STAP1 1128 1132 PF00017 0.261
LIG_SH2_STAP1 1137 1141 PF00017 0.263
LIG_SH2_STAP1 1163 1167 PF00017 0.371
LIG_SH2_STAP1 296 300 PF00017 0.259
LIG_SH2_STAT3 25 28 PF00017 0.398
LIG_SH2_STAT5 1042 1045 PF00017 0.302
LIG_SH2_STAT5 1050 1053 PF00017 0.252
LIG_SH2_STAT5 1066 1069 PF00017 0.302
LIG_SH2_STAT5 1128 1131 PF00017 0.308
LIG_SH2_STAT5 1137 1140 PF00017 0.312
LIG_SH2_STAT5 1161 1164 PF00017 0.280
LIG_SH2_STAT5 1176 1179 PF00017 0.352
LIG_SH2_STAT5 1206 1209 PF00017 0.390
LIG_SH2_STAT5 147 150 PF00017 0.343
LIG_SH2_STAT5 15 18 PF00017 0.261
LIG_SH2_STAT5 25 28 PF00017 0.225
LIG_SH2_STAT5 268 271 PF00017 0.308
LIG_SH2_STAT5 328 331 PF00017 0.443
LIG_SH2_STAT5 417 420 PF00017 0.270
LIG_SH2_STAT5 46 49 PF00017 0.257
LIG_SH2_STAT5 993 996 PF00017 0.335
LIG_SH2_STAT5 998 1001 PF00017 0.302
LIG_SH3_3 338 344 PF00018 0.281
LIG_SH3_3 350 356 PF00018 0.204
LIG_SH3_3 483 489 PF00018 0.515
LIG_SH3_3 55 61 PF00018 0.268
LIG_SH3_3 593 599 PF00018 0.453
LIG_SH3_3 633 639 PF00018 0.601
LIG_SH3_3 796 802 PF00018 0.572
LIG_SUMO_SIM_anti_2 1196 1201 PF11976 0.412
LIG_SUMO_SIM_anti_2 123 132 PF11976 0.306
LIG_SUMO_SIM_anti_2 136 141 PF11976 0.254
LIG_SUMO_SIM_anti_2 483 488 PF11976 0.497
LIG_SUMO_SIM_anti_2 697 704 PF11976 0.433
LIG_SUMO_SIM_anti_2 877 883 PF11976 0.391
LIG_SUMO_SIM_par_1 123 132 PF11976 0.343
LIG_SUMO_SIM_par_1 73 78 PF11976 0.384
LIG_SUMO_SIM_par_1 880 885 PF11976 0.371
LIG_SUMO_SIM_par_1 936 942 PF11976 0.291
LIG_TYR_ITIM 1015 1020 PF00017 0.352
LIG_TYR_ITIM 1126 1131 PF00017 0.275
LIG_TYR_ITIM 1174 1179 PF00017 0.367
LIG_TYR_ITIM 1204 1209 PF00017 0.358
LIG_TYR_ITIM 326 331 PF00017 0.294
LIG_WRC_WIRS_1 1009 1014 PF05994 0.312
LIG_WRC_WIRS_1 1083 1088 PF05994 0.325
LIG_WRC_WIRS_1 215 220 PF05994 0.352
MOD_CDK_SPxxK_3 1211 1218 PF00069 0.347
MOD_CDK_SPxxK_3 916 923 PF00069 0.345
MOD_CK1_1 1025 1031 PF00069 0.266
MOD_CK1_1 1114 1120 PF00069 0.351
MOD_CK1_1 1166 1172 PF00069 0.276
MOD_CK1_1 1183 1189 PF00069 0.427
MOD_CK1_1 1265 1271 PF00069 0.618
MOD_CK1_1 176 182 PF00069 0.519
MOD_CK1_1 199 205 PF00069 0.446
MOD_CK1_1 23 29 PF00069 0.262
MOD_CK1_1 294 300 PF00069 0.333
MOD_CK1_1 334 340 PF00069 0.351
MOD_CK1_1 420 426 PF00069 0.297
MOD_CK1_1 543 549 PF00069 0.461
MOD_CK1_1 626 632 PF00069 0.641
MOD_CK1_1 698 704 PF00069 0.330
MOD_CK1_1 803 809 PF00069 0.644
MOD_CK1_1 810 816 PF00069 0.465
MOD_CK1_1 838 844 PF00069 0.641
MOD_CK1_1 918 924 PF00069 0.379
MOD_CK2_1 184 190 PF00069 0.591
MOD_CK2_1 404 410 PF00069 0.293
MOD_CK2_1 452 458 PF00069 0.586
MOD_CK2_1 505 511 PF00069 0.257
MOD_CK2_1 541 547 PF00069 0.409
MOD_CK2_1 703 709 PF00069 0.337
MOD_CK2_1 782 788 PF00069 0.653
MOD_CK2_1 854 860 PF00069 0.653
MOD_CMANNOS 1245 1248 PF00535 0.588
MOD_GlcNHglycan 1024 1027 PF01048 0.266
MOD_GlcNHglycan 1113 1116 PF01048 0.271
MOD_GlcNHglycan 1190 1193 PF01048 0.414
MOD_GlcNHglycan 1264 1267 PF01048 0.577
MOD_GlcNHglycan 143 146 PF01048 0.453
MOD_GlcNHglycan 211 214 PF01048 0.303
MOD_GlcNHglycan 296 299 PF01048 0.384
MOD_GlcNHglycan 335 339 PF01048 0.519
MOD_GlcNHglycan 492 495 PF01048 0.645
MOD_GlcNHglycan 559 562 PF01048 0.398
MOD_GlcNHglycan 600 603 PF01048 0.450
MOD_GlcNHglycan 628 631 PF01048 0.695
MOD_GlcNHglycan 697 700 PF01048 0.499
MOD_GlcNHglycan 765 768 PF01048 0.512
MOD_GlcNHglycan 809 812 PF01048 0.549
MOD_GlcNHglycan 816 819 PF01048 0.534
MOD_GlcNHglycan 872 875 PF01048 0.577
MOD_GlcNHglycan 995 998 PF01048 0.248
MOD_GSK3_1 1000 1007 PF00069 0.249
MOD_GSK3_1 1025 1032 PF00069 0.252
MOD_GSK3_1 1040 1047 PF00069 0.212
MOD_GSK3_1 1116 1123 PF00069 0.349
MOD_GSK3_1 1131 1138 PF00069 0.244
MOD_GSK3_1 1140 1147 PF00069 0.249
MOD_GSK3_1 1162 1169 PF00069 0.292
MOD_GSK3_1 1207 1214 PF00069 0.328
MOD_GSK3_1 161 168 PF00069 0.462
MOD_GSK3_1 224 231 PF00069 0.532
MOD_GSK3_1 266 273 PF00069 0.277
MOD_GSK3_1 376 383 PF00069 0.493
MOD_GSK3_1 420 427 PF00069 0.308
MOD_GSK3_1 575 582 PF00069 0.378
MOD_GSK3_1 584 591 PF00069 0.297
MOD_GSK3_1 617 624 PF00069 0.488
MOD_GSK3_1 71 78 PF00069 0.259
MOD_GSK3_1 731 738 PF00069 0.366
MOD_GSK3_1 778 785 PF00069 0.687
MOD_GSK3_1 803 810 PF00069 0.585
MOD_GSK3_1 837 844 PF00069 0.655
MOD_GSK3_1 905 912 PF00069 0.381
MOD_N-GLC_1 173 178 PF02516 0.633
MOD_N-GLC_1 318 323 PF02516 0.506
MOD_N-GLC_1 404 409 PF02516 0.327
MOD_N-GLC_1 96 101 PF02516 0.546
MOD_NEK2_1 1004 1009 PF00069 0.256
MOD_NEK2_1 1029 1034 PF00069 0.262
MOD_NEK2_1 1082 1087 PF00069 0.342
MOD_NEK2_1 1091 1096 PF00069 0.286
MOD_NEK2_1 1098 1103 PF00069 0.243
MOD_NEK2_1 1124 1129 PF00069 0.293
MOD_NEK2_1 1131 1136 PF00069 0.267
MOD_NEK2_1 1193 1198 PF00069 0.396
MOD_NEK2_1 1207 1212 PF00069 0.333
MOD_NEK2_1 1231 1236 PF00069 0.509
MOD_NEK2_1 140 145 PF00069 0.438
MOD_NEK2_1 165 170 PF00069 0.478
MOD_NEK2_1 348 353 PF00069 0.259
MOD_NEK2_1 380 385 PF00069 0.399
MOD_NEK2_1 48 53 PF00069 0.237
MOD_NEK2_1 521 526 PF00069 0.303
MOD_NEK2_1 575 580 PF00069 0.235
MOD_NEK2_1 71 76 PF00069 0.240
MOD_NEK2_1 936 941 PF00069 0.366
MOD_NEK2_2 1163 1168 PF00069 0.400
MOD_NEK2_2 643 648 PF00069 0.324
MOD_NEK2_2 666 671 PF00069 0.522
MOD_NEK2_2 96 101 PF00069 0.553
MOD_PIKK_1 1131 1137 PF00454 0.319
MOD_PIKK_1 393 399 PF00454 0.424
MOD_PIKK_1 424 430 PF00454 0.332
MOD_PIKK_1 760 766 PF00454 0.439
MOD_PIKK_1 838 844 PF00454 0.664
MOD_PIKK_1 918 924 PF00454 0.351
MOD_PIKK_1 973 979 PF00454 0.345
MOD_PK_1 404 410 PF00069 0.349
MOD_PK_1 909 915 PF00069 0.421
MOD_PKA_2 1180 1186 PF00069 0.366
MOD_PKA_2 176 182 PF00069 0.644
MOD_PKA_2 23 29 PF00069 0.259
MOD_PKA_2 294 300 PF00069 0.359
MOD_PKA_2 588 594 PF00069 0.290
MOD_PKA_2 643 649 PF00069 0.318
MOD_PKA_2 751 757 PF00069 0.527
MOD_PKA_2 758 764 PF00069 0.529
MOD_PKA_2 770 776 PF00069 0.548
MOD_PKA_2 806 812 PF00069 0.527
MOD_PKB_1 902 910 PF00069 0.338
MOD_Plk_1 1120 1126 PF00069 0.313
MOD_Plk_1 1254 1260 PF00069 0.540
MOD_Plk_1 376 382 PF00069 0.439
MOD_Plk_1 404 410 PF00069 0.278
MOD_Plk_1 573 579 PF00069 0.392
MOD_Plk_1 666 672 PF00069 0.446
MOD_Plk_1 676 682 PF00069 0.408
MOD_Plk_1 838 844 PF00069 0.687
MOD_Plk_1 96 102 PF00069 0.544
MOD_Plk_1 971 977 PF00069 0.259
MOD_Plk_2-3 184 190 PF00069 0.422
MOD_Plk_4 1000 1006 PF00069 0.254
MOD_Plk_4 1025 1031 PF00069 0.263
MOD_Plk_4 1033 1039 PF00069 0.276
MOD_Plk_4 1044 1050 PF00069 0.190
MOD_Plk_4 1082 1088 PF00069 0.308
MOD_Plk_4 1135 1141 PF00069 0.299
MOD_Plk_4 1163 1169 PF00069 0.331
MOD_Plk_4 1200 1206 PF00069 0.381
MOD_Plk_4 1207 1213 PF00069 0.338
MOD_Plk_4 1254 1260 PF00069 0.446
MOD_Plk_4 349 355 PF00069 0.289
MOD_Plk_4 376 382 PF00069 0.481
MOD_Plk_4 404 410 PF00069 0.304
MOD_Plk_4 521 527 PF00069 0.349
MOD_Plk_4 54 60 PF00069 0.279
MOD_Plk_4 64 70 PF00069 0.229
MOD_Plk_4 643 649 PF00069 0.401
MOD_Plk_4 666 672 PF00069 0.416
MOD_Plk_4 698 704 PF00069 0.447
MOD_Plk_4 889 895 PF00069 0.402
MOD_Plk_4 909 915 PF00069 0.334
MOD_ProDKin_1 1144 1150 PF00069 0.398
MOD_ProDKin_1 1168 1174 PF00069 0.349
MOD_ProDKin_1 1211 1217 PF00069 0.352
MOD_ProDKin_1 1249 1255 PF00069 0.557
MOD_ProDKin_1 505 511 PF00069 0.297
MOD_ProDKin_1 916 922 PF00069 0.350
MOD_SUMO_rev_2 154 161 PF00179 0.401
TRG_DiLeu_BaEn_1 677 682 PF01217 0.306
TRG_DiLeu_BaLyEn_6 1227 1232 PF01217 0.558
TRG_DiLeu_BaLyEn_6 2 7 PF01217 0.289
TRG_DiLeu_BaLyEn_6 67 72 PF01217 0.322
TRG_ENDOCYTIC_2 1005 1008 PF00928 0.274
TRG_ENDOCYTIC_2 1017 1020 PF00928 0.236
TRG_ENDOCYTIC_2 1128 1131 PF00928 0.279
TRG_ENDOCYTIC_2 1176 1179 PF00928 0.340
TRG_ENDOCYTIC_2 1206 1209 PF00928 0.291
TRG_ENDOCYTIC_2 1238 1241 PF00928 0.440
TRG_ENDOCYTIC_2 328 331 PF00928 0.426
TRG_ENDOCYTIC_2 36 39 PF00928 0.279
TRG_ENDOCYTIC_2 46 49 PF00928 0.280
TRG_ENDOCYTIC_2 84 87 PF00928 0.372
TRG_ER_diArg_1 1 3 PF00400 0.357
TRG_ER_diArg_1 100 102 PF00400 0.478
TRG_ER_diArg_1 1226 1228 PF00400 0.441
TRG_ER_diArg_1 177 180 PF00400 0.476
TRG_ER_diArg_1 389 392 PF00400 0.661
TRG_ER_diArg_1 471 473 PF00400 0.527
TRG_ER_diArg_1 535 538 PF00400 0.380
TRG_ER_diArg_1 899 902 PF00400 0.494
TRG_NES_CRM1_1 695 709 PF08389 0.298
TRG_NLS_MonoExtC_3 278 283 PF00514 0.310
TRG_NLS_MonoExtC_3 87 93 PF00514 0.384
TRG_Pf-PMV_PEXEL_1 102 107 PF00026 0.309
TRG_Pf-PMV_PEXEL_1 33 37 PF00026 0.398
TRG_Pf-PMV_PEXEL_1 5 9 PF00026 0.313
TRG_Pf-PMV_PEXEL_1 673 677 PF00026 0.452
TRG_Pf-PMV_PEXEL_1 831 836 PF00026 0.597

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKQ9 Leptomonas seymouri 29% 85%
A0A0N1PF54 Leptomonas seymouri 61% 98%
A0A0S4ITW3 Bodo saltans 41% 92%
A0A1X0P1Z0 Trypanosomatidae 49% 100%
A0A1X0PA06 Trypanosomatidae 30% 99%
A0A3Q8IFQ5 Leishmania donovani 93% 100%
A0A3Q8INM6 Leishmania donovani 28% 100%
A0A3R7NV92 Trypanosoma rangeli 31% 100%
A0A3S5IS27 Trypanosoma rangeli 48% 100%
A4H7E2 Leishmania braziliensis 28% 100%
A4H7E4 Leishmania braziliensis 28% 100%
A4HAY0 Leishmania braziliensis 29% 85%
A4HIF8 Leishmania braziliensis 75% 100%
A4HVT2 Leishmania infantum 28% 100%
A4I5Q4 Leishmania infantum 93% 100%
A4IA89 Leishmania infantum 28% 100%
C9ZR23 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 100%
E9APH7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9B0Z9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
E9B5B1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
P57792 Arabidopsis thaliana 28% 100%
Q4Q2M2 Leishmania major 27% 100%
Q4QG01 Leishmania major 28% 100%
Q6VXY9 Leishmania donovani 28% 100%
Q9LK90 Arabidopsis thaliana 28% 100%
Q9SX33 Arabidopsis thaliana 26% 100%
V5BQC7 Trypanosoma cruzi 32% 100%
V5DCY9 Trypanosoma cruzi 47% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS