Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q760_LEIMA

TriTrypDb:

LmjF.30.2330 , LMJLV39_300030600 , LMJSD75_300030200

Length:

340

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q760

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q760

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	96	100	PF00656	0.586
CLV_NRD_NRD_1	255	257	PF00675	0.567
CLV_PCSK_SKI1_1	109	113	PF00082	0.501
CLV_PCSK_SKI1_1	132	136	PF00082	0.495
DEG_SPOP_SBC_1	35	39	PF00917	0.613
DOC_MAPK_gen_1	107	116	PF00069	0.495
DOC_PP1_RVXF_1	107	114	PF00149	0.473
DOC_PP1_RVXF_1	130	137	PF00149	0.441
DOC_USP7_MATH_1	188	192	PF00917	0.451
DOC_USP7_MATH_1	86	90	PF00917	0.665
DOC_WW_Pin1_4	27	32	PF00397	0.541
DOC_WW_Pin1_4	65	70	PF00397	0.605
LIG_14-3-3_CanoR_1	107	112	PF00244	0.509
LIG_14-3-3_CanoR_1	115	120	PF00244	0.377
LIG_14-3-3_CanoR_1	132	137	PF00244	0.443
LIG_14-3-3_CanoR_1	163	171	PF00244	0.497
LIG_14-3-3_CanoR_1	20	28	PF00244	0.570
LIG_14-3-3_CanoR_1	249	253	PF00244	0.499
LIG_APCC_ABBA_1	59	64	PF00400	0.474
LIG_BRCT_BRCA1_1	109	113	PF00533	0.599
LIG_deltaCOP1_diTrp_1	287	295	PF00928	0.567
LIG_FHA_1	170	176	PF00498	0.433
LIG_FHA_1	217	223	PF00498	0.513
LIG_FHA_1	273	279	PF00498	0.616
LIG_FHA_1	35	41	PF00498	0.666
LIG_FHA_1	54	60	PF00498	0.322
LIG_FHA_2	144	150	PF00498	0.504
LIG_FHA_2	200	206	PF00498	0.568
LIG_LIR_Gen_1	102	113	PF02991	0.457
LIG_LIR_Gen_1	118	125	PF02991	0.449
LIG_LIR_Gen_1	227	235	PF02991	0.456
LIG_LIR_Gen_1	294	303	PF02991	0.589
LIG_LIR_Nem_3	102	108	PF02991	0.441
LIG_LIR_Nem_3	110	116	PF02991	0.468
LIG_LIR_Nem_3	118	122	PF02991	0.428
LIG_LIR_Nem_3	227	233	PF02991	0.465
LIG_MLH1_MIPbox_1	109	113	PF16413	0.599
LIG_NRBOX	202	208	PF00104	0.410
LIG_REV1ctd_RIR_1	110	119	PF16727	0.561
LIG_SH2_STAP1	328	332	PF00017	0.529
LIG_SH2_STAT5	174	177	PF00017	0.435
LIG_SH2_STAT5	328	331	PF00017	0.521
LIG_SH2_STAT5	62	65	PF00017	0.465
LIG_SH2_STAT5	74	77	PF00017	0.584
LIG_SH3_3	131	137	PF00018	0.430
LIG_SH3_3	28	34	PF00018	0.617
LIG_TRAF2_1	166	169	PF00917	0.505
LIG_TRAF2_1	285	288	PF00917	0.432
LIG_TRAF2_2	137	142	PF00917	0.530
LIG_WRC_WIRS_1	116	121	PF05994	0.519
MOD_CDC14_SPxK_1	30	33	PF00782	0.640
MOD_CDK_SPxK_1	27	33	PF00069	0.616
MOD_CK1_1	89	95	PF00069	0.546
MOD_CK2_1	163	169	PF00069	0.513
MOD_CK2_1	199	205	PF00069	0.573
MOD_CK2_1	282	288	PF00069	0.483
MOD_CK2_1	49	55	PF00069	0.449
MOD_GlcNHglycan	165	168	PF01048	0.436
MOD_GlcNHglycan	190	193	PF01048	0.516
MOD_GlcNHglycan	283	287	PF01048	0.598
MOD_GlcNHglycan	298	301	PF01048	0.498
MOD_GlcNHglycan	84	87	PF01048	0.463
MOD_GSK3_1	244	251	PF00069	0.628
MOD_GSK3_1	272	279	PF00069	0.575
MOD_GSK3_1	319	326	PF00069	0.617
MOD_GSK3_1	36	43	PF00069	0.466
MOD_GSK3_1	49	56	PF00069	0.460
MOD_GSK3_1	82	89	PF00069	0.407
MOD_N-GLC_1	126	131	PF02516	0.493
MOD_NEK2_1	198	203	PF00069	0.405
MOD_NEK2_1	310	315	PF00069	0.579
MOD_NEK2_1	40	45	PF00069	0.478
MOD_NEK2_1	82	87	PF00069	0.395
MOD_NEK2_2	5	10	PF00069	0.432
MOD_NEK2_2	62	67	PF00069	0.452
MOD_PIKK_1	190	196	PF00454	0.391
MOD_PK_1	107	113	PF00069	0.526
MOD_PKA_2	248	254	PF00069	0.488
MOD_PKA_2	82	88	PF00069	0.485
MOD_PKA_2	89	95	PF00069	0.518
MOD_Plk_1	126	132	PF00069	0.487
MOD_Plk_1	222	228	PF00069	0.450
MOD_Plk_1	244	250	PF00069	0.560
MOD_Plk_1	35	41	PF00069	0.627
MOD_Plk_2-3	199	205	PF00069	0.509
MOD_Plk_4	107	113	PF00069	0.590
MOD_Plk_4	36	42	PF00069	0.629
MOD_Plk_4	5	11	PF00069	0.437
MOD_ProDKin_1	27	33	PF00069	0.546
MOD_ProDKin_1	65	71	PF00069	0.600
MOD_SUMO_for_1	270	273	PF00179	0.580
MOD_SUMO_rev_2	13	17	PF00179	0.551
MOD_SUMO_rev_2	259	265	PF00179	0.488
TRG_DiLeu_BaEn_1	36	41	PF01217	0.545
TRG_ER_diArg_1	114	117	PF00400	0.424

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8P9	Leptomonas seymouri	51%	97%
A0A3Q8II20	Leishmania donovani	89%	97%
A4HIG5	Leishmania braziliensis	62%	96%
A4I5R1	Leishmania infantum	89%	97%
E9B106	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	97%