LeishMANIAdb
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Present in the outer mitochondrial membrane proteome 34

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Present in the outer mitochondrial membrane proteome 34
Gene product:
Present in the outer mitochondrial membrane proteome 31
Species:
Leishmania major
UniProt:
Q4Q753_LEIMA
TriTrypDb:
LmjF.30.2400 * , LMJLV39_300031300 * , LMJSD75_300030900 *
Length:
273

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005741 mitochondrial outer membrane 5 2
GO:0016020 membrane 2 3
GO:0019867 outer membrane 3 2
GO:0031090 organelle membrane 3 2
GO:0031966 mitochondrial membrane 4 2
GO:0031968 organelle outer membrane 4 2
GO:0098588 bounding membrane of organelle 4 2
GO:0110165 cellular anatomical entity 1 3
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Expansion

Sequence features

Q4Q753
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q753

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 162 164 PF00675 0.365
CLV_PCSK_FUR_1 171 175 PF00082 0.377
CLV_PCSK_KEX2_1 161 163 PF00082 0.352
CLV_PCSK_KEX2_1 173 175 PF00082 0.276
CLV_PCSK_PC1ET2_1 173 175 PF00082 0.301
CLV_PCSK_PC7_1 169 175 PF00082 0.430
CLV_PCSK_SKI1_1 173 177 PF00082 0.301
CLV_PCSK_SKI1_1 71 75 PF00082 0.351
CLV_PCSK_SKI1_1 99 103 PF00082 0.532
DEG_APCC_DBOX_1 98 106 PF00400 0.405
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PBK1 Leptomonas seymouri 70% 100%
A0A0S4ILA8 Bodo saltans 44% 100%
A0A1X0P1K3 Trypanosomatidae 49% 100%
A0A3S7X3K3 Leishmania donovani 96% 100%
A0A422NWC9 Trypanosoma rangeli 49% 100%
A4HIH1 Leishmania braziliensis 87% 100%
A4I5R8 Leishmania infantum 96% 100%
C9ZR37 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 49% 85%
E9B113 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
V5AWV4 Trypanosoma cruzi 52% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS