LeishMANIAdb
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Translation machinery associated TMA7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Translation machinery associated TMA7
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
Q4Q718_LEIMA
TriTrypDb:
Length:
49

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q718
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q718

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 10 14 PF00082 0.279
DOC_USP7_UBL2_3 13 17 PF12436 0.312
DOC_USP7_UBL2_3 37 41 PF12436 0.365
LIG_BIR_II_1 1 5 PF00653 0.312
LIG_SH3_4 10 17 PF00018 0.337
MOD_SUMO_for_1 15 18 PF00179 0.312

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4IU14 Bodo saltans 57% 67%
A0A3Q8IJM0 Leishmania donovani 98% 100%
A4HIK8 Leishmania braziliensis 88% 100%
A4I5V3 Leishmania infantum 98% 100%
C9ZR71 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 71% 94%
E9B148 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
V5DP02 Trypanosoma cruzi 77% 94%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS