Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q713_LEIMA

TriTrypDb:

LmjF.30.2800 , LMJLV39_300035600 , LMJSD75_300035000

Length:

274

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

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Expansion

Sequence features

Q4Q713

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q713

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	261	265	PF00656	0.631
CLV_NRD_NRD_1	124	126	PF00675	0.443
CLV_NRD_NRD_1	2	4	PF00675	0.507
CLV_NRD_NRD_1	267	269	PF00675	0.402
CLV_PCSK_KEX2_1	267	269	PF00082	0.377
CLV_PCSK_SKI1_1	125	129	PF00082	0.391
CLV_PCSK_SKI1_1	4	8	PF00082	0.455
DEG_APCC_DBOX_1	124	132	PF00400	0.575
DEG_Nend_Nbox_1	1	3	PF02207	0.695
DEG_SPOP_SBC_1	255	259	PF00917	0.599

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4B3	Leptomonas seymouri	67%	100%
A0A0S4IU47	Bodo saltans	36%	75%
A0A1X0P2M0	Trypanosomatidae	48%	100%
A0A3R7L2S3	Trypanosoma rangeli	47%	100%
A0A3S7X3P3	Leishmania donovani	93%	100%
A4HIL3	Leishmania braziliensis	82%	100%
A4I5V8	Leishmania infantum	93%	100%
E9B153	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%

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