BSD domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q705_LEIMA

TriTrypDb:

LmjF.30.2870 , LMJLV39_300036500 , LMJSD75_300035800

Length:

483

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q705

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q705

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	11	15	PF00656	0.635
CLV_C14_Caspase3-7	357	361	PF00656	0.567
CLV_C14_Caspase3-7	452	456	PF00656	0.570
CLV_NRD_NRD_1	228	230	PF00675	0.573
CLV_NRD_NRD_1	297	299	PF00675	0.549
CLV_NRD_NRD_1	316	318	PF00675	0.370
CLV_PCSK_SKI1_1	378	382	PF00082	0.524
DEG_COP1_1	54	62	PF00400	0.489
DEG_Nend_Nbox_1	1	3	PF02207	0.580
DEG_SCF_FBW7_1	62	68	PF00400	0.464
DOC_CKS1_1	153	158	PF01111	0.373
DOC_CKS1_1	62	67	PF01111	0.534
DOC_MAPK_gen_1	296	303	PF00069	0.526
DOC_PP2B_LxvP_1	115	118	PF13499	0.639
DOC_PP2B_LxvP_1	126	129	PF13499	0.684
DOC_PP2B_LxvP_1	57	60	PF13499	0.541
DOC_PP4_MxPP_1	63	66	PF00568	0.553
DOC_USP7_MATH_1	15	19	PF00917	0.609
DOC_USP7_MATH_1	238	242	PF00917	0.663
DOC_USP7_MATH_1	35	39	PF00917	0.478
DOC_USP7_MATH_1	351	355	PF00917	0.598
DOC_USP7_MATH_1	389	393	PF00917	0.673
DOC_USP7_MATH_1	430	434	PF00917	0.683
DOC_USP7_MATH_1	436	440	PF00917	0.663
DOC_USP7_MATH_1	453	457	PF00917	0.787
DOC_USP7_MATH_1	465	469	PF00917	0.580
DOC_USP7_UBL2_3	267	271	PF12436	0.673
DOC_WW_Pin1_4	117	122	PF00397	0.687
DOC_WW_Pin1_4	127	132	PF00397	0.717
DOC_WW_Pin1_4	152	157	PF00397	0.542
DOC_WW_Pin1_4	391	396	PF00397	0.751
DOC_WW_Pin1_4	398	403	PF00397	0.724
DOC_WW_Pin1_4	411	416	PF00397	0.712
DOC_WW_Pin1_4	442	447	PF00397	0.773
DOC_WW_Pin1_4	61	66	PF00397	0.487
DOC_WW_Pin1_4	90	95	PF00397	0.496
LIG_14-3-3_CanoR_1	172	177	PF00244	0.454
LIG_14-3-3_CanoR_1	180	189	PF00244	0.437
LIG_14-3-3_CanoR_1	450	460	PF00244	0.775
LIG_Actin_WH2_2	207	224	PF00022	0.469
LIG_Actin_WH2_2	275	293	PF00022	0.369
LIG_BIR_III_2	116	120	PF00653	0.460
LIG_CtBP_PxDLS_1	446	450	PF00389	0.793
LIG_deltaCOP1_diTrp_1	184	193	PF00928	0.390
LIG_deltaCOP1_diTrp_1	73	78	PF00928	0.494
LIG_FHA_1	28	34	PF00498	0.562
LIG_FHA_1	430	436	PF00498	0.659
LIG_FHA_1	54	60	PF00498	0.504
LIG_FHA_1	87	93	PF00498	0.507
LIG_FHA_1	94	100	PF00498	0.515
LIG_FHA_2	180	186	PF00498	0.555
LIG_FHA_2	355	361	PF00498	0.578
LIG_LIR_Apic_2	175	179	PF02991	0.566
LIG_LIR_Gen_1	102	112	PF02991	0.493
LIG_LIR_Gen_1	185	195	PF02991	0.402
LIG_LIR_Gen_1	270	280	PF02991	0.475
LIG_LIR_Gen_1	285	294	PF02991	0.498
LIG_LIR_Gen_1	331	342	PF02991	0.503
LIG_LIR_Gen_1	365	371	PF02991	0.414
LIG_LIR_Nem_3	166	171	PF02991	0.530
LIG_LIR_Nem_3	185	191	PF02991	0.400
LIG_LIR_Nem_3	270	276	PF02991	0.464
LIG_LIR_Nem_3	285	290	PF02991	0.484
LIG_LIR_Nem_3	331	337	PF02991	0.505
LIG_LIR_Nem_3	365	370	PF02991	0.415
LIG_SH2_CRK	334	338	PF00017	0.491
LIG_SH2_NCK_1	154	158	PF00017	0.585
LIG_SH2_NCK_1	280	284	PF00017	0.530
LIG_SH2_PTP2	176	179	PF00017	0.568
LIG_SH2_STAT5	154	157	PF00017	0.542
LIG_SH2_STAT5	163	166	PF00017	0.529
LIG_SH2_STAT5	176	179	PF00017	0.358
LIG_SH2_STAT5	376	379	PF00017	0.490
LIG_SH3_2	118	123	PF14604	0.721
LIG_SH3_3	115	121	PF00018	0.620
LIG_SH3_3	150	156	PF00018	0.379
LIG_SH3_3	228	234	PF00018	0.618
LIG_SH3_3	396	402	PF00018	0.746
LIG_SUMO_SIM_par_1	54	61	PF11976	0.643
LIG_TRAF2_1	468	471	PF00917	0.696
LIG_TRAF2_1	51	54	PF00917	0.632
LIG_TRAF2_1	72	75	PF00917	0.477
LIG_TRAF2_2	415	420	PF00917	0.562
LIG_UBA3_1	310	318	PF00899	0.439
LIG_UBA3_1	366	372	PF00899	0.465
MOD_CDC14_SPxK_1	120	123	PF00782	0.512
MOD_CDK_SPK_2	391	396	PF00069	0.747
MOD_CDK_SPxK_1	117	123	PF00069	0.496
MOD_CK1_1	127	133	PF00069	0.760
MOD_CK1_1	18	24	PF00069	0.658
MOD_CK1_1	354	360	PF00069	0.560
MOD_CK1_1	400	406	PF00069	0.713
MOD_CK2_1	418	424	PF00069	0.650
MOD_CK2_1	442	448	PF00069	0.746
MOD_CK2_1	465	471	PF00069	0.704
MOD_CK2_1	69	75	PF00069	0.525
MOD_CK2_1	99	105	PF00069	0.495
MOD_GlcNHglycan	10	13	PF01048	0.606
MOD_GlcNHglycan	125	129	PF01048	0.750
MOD_GlcNHglycan	137	141	PF01048	0.479
MOD_GlcNHglycan	240	243	PF01048	0.751
MOD_GlcNHglycan	362	365	PF01048	0.547
MOD_GlcNHglycan	389	392	PF01048	0.621
MOD_GlcNHglycan	408	411	PF01048	0.780
MOD_GlcNHglycan	432	435	PF01048	0.710
MOD_GlcNHglycan	44	47	PF01048	0.706
MOD_GlcNHglycan	451	454	PF01048	0.726
MOD_GlcNHglycan	455	458	PF01048	0.704
MOD_GlcNHglycan	466	470	PF01048	0.632
MOD_GSK3_1	129	136	PF00069	0.689
MOD_GSK3_1	206	213	PF00069	0.432
MOD_GSK3_1	324	331	PF00069	0.423
MOD_GSK3_1	354	361	PF00069	0.582
MOD_GSK3_1	387	394	PF00069	0.589
MOD_GSK3_1	420	427	PF00069	0.715
MOD_GSK3_1	438	445	PF00069	0.602
MOD_GSK3_1	449	456	PF00069	0.786
MOD_GSK3_1	465	472	PF00069	0.503
MOD_GSK3_1	61	68	PF00069	0.509
MOD_GSK3_1	86	93	PF00069	0.505
MOD_LATS_1	265	271	PF00433	0.549
MOD_N-GLC_1	133	138	PF02516	0.617
MOD_N-GLC_2	88	90	PF02516	0.450
MOD_NEK2_1	107	112	PF00069	0.575
MOD_NEK2_1	210	215	PF00069	0.528
MOD_NEK2_1	266	271	PF00069	0.621
MOD_NEK2_1	310	315	PF00069	0.438
MOD_NEK2_1	324	329	PF00069	0.333
MOD_NEK2_1	358	363	PF00069	0.523
MOD_NEK2_1	449	454	PF00069	0.705
MOD_PK_1	55	61	PF00069	0.619
MOD_PKA_2	179	185	PF00069	0.519
MOD_PKA_2	27	33	PF00069	0.637
MOD_PKA_2	290	296	PF00069	0.485
MOD_PKA_2	449	455	PF00069	0.785
MOD_Plk_1	469	475	PF00069	0.682
MOD_Plk_1	53	59	PF00069	0.599
MOD_Plk_1	99	105	PF00069	0.490
MOD_Plk_4	206	212	PF00069	0.555
MOD_Plk_4	310	316	PF00069	0.507
MOD_Plk_4	324	330	PF00069	0.373
MOD_Plk_4	354	360	PF00069	0.458
MOD_Plk_4	362	368	PF00069	0.398
MOD_Plk_4	99	105	PF00069	0.498
MOD_ProDKin_1	117	123	PF00069	0.692
MOD_ProDKin_1	127	133	PF00069	0.709
MOD_ProDKin_1	152	158	PF00069	0.547
MOD_ProDKin_1	391	397	PF00069	0.752
MOD_ProDKin_1	398	404	PF00069	0.725
MOD_ProDKin_1	411	417	PF00069	0.716
MOD_ProDKin_1	442	448	PF00069	0.773
MOD_ProDKin_1	61	67	PF00069	0.495
MOD_ProDKin_1	90	96	PF00069	0.499
MOD_SUMO_for_1	234	237	PF00179	0.719
MOD_SUMO_rev_2	100	110	PF00179	0.569
MOD_SUMO_rev_2	468	478	PF00179	0.726
TRG_DiLeu_BaEn_4	261	267	PF01217	0.638
TRG_DiLeu_BaLyEn_6	338	343	PF01217	0.460
TRG_ENDOCYTIC_2	280	283	PF00928	0.586
TRG_ENDOCYTIC_2	334	337	PF00928	0.491
TRG_ER_diArg_1	171	174	PF00400	0.343
TRG_Pf-PMV_PEXEL_1	341	345	PF00026	0.522

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4Q4	Leptomonas seymouri	44%	99%
A0A1X0P2L0	Trypanosomatidae	28%	100%
A0A3Q8IC68	Leishmania donovani	88%	100%
A0A422N306	Trypanosoma rangeli	30%	100%
A4HIM1	Leishmania braziliensis	70%	99%
A4I5W6	Leishmania infantum	88%	100%
C9ZR88	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
V5DNX2	Trypanosoma cruzi	26%	100%