Chalcone_isomerase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q6Z9_LEIMA

TriTrypDb:

LmjF.30.2930 , LMJLV39_300037300 , LMJSD75_300036400

Length:

191


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Q4Q6Z9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6Z9


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	128	132	PF00656	0.438
CLV_NRD_NRD_1	166	168	PF00675	0.639
CLV_PCSK_KEX2_1	166	168	PF00082	0.639
CLV_PCSK_SKI1_1	101	105	PF00082	0.636
CLV_PCSK_SKI1_1	87	91	PF00082	0.634
DEG_APCC_DBOX_1	9	17	PF00400	0.410
DOC_CYCLIN_yCln2_LP_2	77	83	PF00134	0.384
DOC_MAPK_gen_1	166	177	PF00069	0.429
DOC_PP4_FxxP_1	177	180	PF00568	0.393
DOC_PP4_FxxP_1	187	190	PF00568	0.416
DOC_WW_Pin1_4	176	181	PF00397	0.436
DOC_WW_Pin1_4	95	100	PF00397	0.467
LIG_14-3-3_CanoR_1	10	14	PF00244	0.443
LIG_FHA_1	104	110	PF00498	0.449
LIG_FHA_1	69	75	PF00498	0.430
LIG_FHA_1	76	82	PF00498	0.381
LIG_LIR_Apic_2	184	190	PF02991	0.458
LIG_LIR_Nem_3	26	32	PF02991	0.599
LIG_MYND_1	137	141	PF01753	0.425
LIG_Pex14_2	187	191	PF04695	0.492
LIG_SH2_STAT3	32	35	PF00017	0.415
LIG_SH2_STAT5	27	30	PF00017	0.621
LIG_SH2_STAT5	32	35	PF00017	0.491
LIG_WRC_WIRS_1	104	109	PF05994	0.465
LIG_WRC_WIRS_1	69	74	PF05994	0.454
MOD_CDK_SPxK_1	95	101	PF00069	0.469
MOD_CK1_1	4	10	PF00069	0.496
MOD_CK2_1	148	154	PF00069	0.422
MOD_GlcNHglycan	150	153	PF01048	0.634
MOD_GlcNHglycan	167	170	PF01048	0.498
MOD_GlcNHglycan	18	21	PF01048	0.150
MOD_GlcNHglycan	3	6	PF01048	0.488
MOD_GlcNHglycan	51	54	PF01048	0.623
MOD_GSK3_1	64	71	PF00069	0.487
MOD_NEK2_1	129	134	PF00069	0.469
MOD_NEK2_1	165	170	PF00069	0.304
MOD_NEK2_1	23	28	PF00069	0.415
MOD_PKA_2	165	171	PF00069	0.437
MOD_PKA_2	9	15	PF00069	0.342
MOD_Plk_1	183	189	PF00069	0.376
MOD_Plk_1	56	62	PF00069	0.452
MOD_Plk_4	23	29	PF00069	0.378
MOD_Plk_4	4	10	PF00069	0.521
MOD_ProDKin_1	176	182	PF00069	0.435
MOD_ProDKin_1	95	101	PF00069	0.469
MOD_SUMO_for_1	118	121	PF00179	0.440
TRG_ER_diArg_1	165	167	PF00400	0.441
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.656


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCB6	Leptomonas seymouri	61%	100%
A0A0S4ITI4	Bodo saltans	31%	83%
A0A1X0P1H2	Trypanosomatidae	36%	97%
A0A3Q8IJN4	Leishmania donovani	95%	100%
A0A3R7M429	Trypanosoma rangeli	39%	100%
A4HIM7	Leishmania braziliensis	82%	100%
A4I5X2	Leishmania infantum	95%	100%
C9ZR96	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
E9B166	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%