Putative Lsm5p

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Putative Lsm5p

Gene product:

Lsm5p, putative

Species:

Leishmania major

UniProt:

Q4Q6Z0_LEIMA

TriTrypDb:

LmjF.30.3015 , LMJLV39_300038300 , LMJSD75_300037400

Length:

128

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6Z0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6Z0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	63	65	PF00675	0.261
CLV_PCSK_KEX2_1	15	17	PF00082	0.477
CLV_PCSK_KEX2_1	61	63	PF00082	0.245
CLV_PCSK_PC1ET2_1	15	17	PF00082	0.463
CLV_PCSK_PC1ET2_1	61	63	PF00082	0.242
CLV_PCSK_PC7_1	58	64	PF00082	0.261
CLV_PCSK_SKI1_1	58	62	PF00082	0.256
DEG_SCF_TRCP1_1	94	99	PF00400	0.585
DOC_MAPK_gen_1	15	22	PF00069	0.329
DOC_MAPK_RevD_3	49	64	PF00069	0.474
DOC_USP7_MATH_1	112	116	PF00917	0.553
DOC_USP7_MATH_1	123	127	PF00917	0.467
DOC_USP7_MATH_1	4	8	PF00917	0.581
LIG_14-3-3_CanoR_1	110	120	PF00244	0.530
LIG_14-3-3_CanoR_1	25	31	PF00244	0.484
LIG_14-3-3_CanoR_1	39	44	PF00244	0.461
LIG_14-3-3_CanoR_1	84	89	PF00244	0.427
LIG_FHA_1	35	41	PF00498	0.435
LIG_FHA_2	27	33	PF00498	0.490
LIG_FHA_2	50	56	PF00498	0.435
LIG_FHA_2	70	76	PF00498	0.345
LIG_LIR_Gen_1	75	83	PF02991	0.457
LIG_LIR_Nem_3	75	80	PF02991	0.457
LIG_SH2_CRK	77	81	PF00017	0.441
LIG_SH2_STAP1	77	81	PF00017	0.498
LIG_SH2_STAT5	21	24	PF00017	0.535
LIG_SUMO_SIM_par_1	39	45	PF11976	0.535
MOD_CK1_1	34	40	PF00069	0.516
MOD_CK1_1	42	48	PF00069	0.469
MOD_CK1_1	87	93	PF00069	0.431
MOD_CK1_1	95	101	PF00069	0.455
MOD_CK2_1	49	55	PF00069	0.431
MOD_CK2_1	69	75	PF00069	0.345
MOD_GlcNHglycan	7	10	PF01048	0.631
MOD_GlcNHglycan	94	97	PF01048	0.465
MOD_GSK3_1	83	90	PF00069	0.446
MOD_GSK3_1	92	99	PF00069	0.387
MOD_N-GLC_1	112	117	PF02516	0.616
MOD_N-GLC_1	26	31	PF02516	0.184
MOD_PK_1	84	90	PF00069	0.427
MOD_PKA_2	83	89	PF00069	0.561
MOD_Plk_1	112	118	PF00069	0.546
MOD_Plk_1	26	32	PF00069	0.480
MOD_Plk_1	99	105	PF00069	0.491
MOD_Plk_4	31	37	PF00069	0.487
MOD_Plk_4	84	90	PF00069	0.448
MOD_Plk_4	99	105	PF00069	0.467
TRG_DiLeu_BaEn_1	14	19	PF01217	0.453
TRG_ENDOCYTIC_2	77	80	PF00928	0.442
TRG_ER_diArg_1	56	59	PF00400	0.450
TRG_ER_diArg_1	62	64	PF00400	0.433
TRG_NLS_MonoCore_2	60	65	PF00514	0.456
TRG_NLS_MonoExtN_4	58	65	PF00514	0.443

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6D6	Leptomonas seymouri	81%	96%
A0A0S4IPA9	Bodo saltans	39%	100%
A0A1X0P2Y8	Trypanosomatidae	54%	100%
A0A3S7X3R7	Leishmania donovani	94%	100%
A0A422P0R9	Trypanosoma rangeli	54%	100%
A4HIN4	Leishmania braziliensis	86%	100%
A4I5Y1	Leishmania infantum	95%	100%
C9ZRA7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
E9B174	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
V5BX96	Trypanosoma cruzi	54%	100%