LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Protein kinase-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase-like protein
Gene product:
STE/STE11 serine/threonine-protein kinase, putative
Species:
Leishmania major
UniProt:
Q4Q6Y5_LEIMA
TriTrypDb:
LmjF.30.3050 * , LMJLV39_300038800 * , LMJSD75_300037900 *
Length:
1899

Annotations

LeishMANIAdb annotations

Contains several domains (including N-terminal, extracellular sensor domains) fused to a C-terminal STE11-type protein kinase domain. . The C-terminal TM domain preceding the kinase domain seemingly evolved de novo, with an ancertain number of TM segments (but odd in number).. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 2, no: 7
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 2
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9

Expansion

Sequence features

Q4Q6Y5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 9
GO:0006793 phosphorus metabolic process 3 9
GO:0006796 phosphate-containing compound metabolic process 4 9
GO:0006807 nitrogen compound metabolic process 2 9
GO:0008152 metabolic process 1 9
GO:0009987 cellular process 1 9
GO:0016310 phosphorylation 5 9
GO:0019538 protein metabolic process 3 9
GO:0036211 protein modification process 4 9
GO:0043170 macromolecule metabolic process 3 9
GO:0043412 macromolecule modification 4 9
GO:0044237 cellular metabolic process 2 9
GO:0044238 primary metabolic process 2 9
GO:0071704 organic substance metabolic process 2 9
GO:1901564 organonitrogen compound metabolic process 3 9
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 9
GO:0003824 catalytic activity 1 10
GO:0004672 protein kinase activity 3 9
GO:0004674 protein serine/threonine kinase activity 4 3
GO:0005488 binding 1 9
GO:0005524 ATP binding 5 9
GO:0016301 kinase activity 4 9
GO:0016740 transferase activity 2 10
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 9
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 9
GO:0017076 purine nucleotide binding 4 9
GO:0030554 adenyl nucleotide binding 5 9
GO:0032553 ribonucleotide binding 3 9
GO:0032555 purine ribonucleotide binding 4 9
GO:0032559 adenyl ribonucleotide binding 5 9
GO:0035639 purine ribonucleoside triphosphate binding 4 9
GO:0036094 small molecule binding 2 9
GO:0043167 ion binding 2 9
GO:0043168 anion binding 3 9
GO:0097159 organic cyclic compound binding 2 9
GO:0097367 carbohydrate derivative binding 2 9
GO:0140096 catalytic activity, acting on a protein 2 9
GO:1901265 nucleoside phosphate binding 3 9
GO:1901363 heterocyclic compound binding 2 9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1256 1260 PF00656 0.446
CLV_C14_Caspase3-7 14 18 PF00656 0.400
CLV_C14_Caspase3-7 1830 1834 PF00656 0.675
CLV_C14_Caspase3-7 260 264 PF00656 0.284
CLV_C14_Caspase3-7 577 581 PF00656 0.435
CLV_NRD_NRD_1 1040 1042 PF00675 0.610
CLV_NRD_NRD_1 1065 1067 PF00675 0.572
CLV_NRD_NRD_1 1087 1089 PF00675 0.583
CLV_NRD_NRD_1 119 121 PF00675 0.604
CLV_NRD_NRD_1 1196 1198 PF00675 0.536
CLV_NRD_NRD_1 1226 1228 PF00675 0.329
CLV_NRD_NRD_1 236 238 PF00675 0.590
CLV_NRD_NRD_1 528 530 PF00675 0.610
CLV_NRD_NRD_1 872 874 PF00675 0.637
CLV_NRD_NRD_1 94 96 PF00675 0.647
CLV_PCSK_KEX2_1 1042 1044 PF00082 0.602
CLV_PCSK_KEX2_1 1065 1067 PF00082 0.570
CLV_PCSK_KEX2_1 1087 1089 PF00082 0.583
CLV_PCSK_KEX2_1 119 121 PF00082 0.604
CLV_PCSK_KEX2_1 1215 1217 PF00082 0.354
CLV_PCSK_KEX2_1 1225 1227 PF00082 0.285
CLV_PCSK_KEX2_1 1806 1808 PF00082 0.308
CLV_PCSK_KEX2_1 236 238 PF00082 0.590
CLV_PCSK_KEX2_1 370 372 PF00082 0.561
CLV_PCSK_KEX2_1 528 530 PF00082 0.610
CLV_PCSK_KEX2_1 872 874 PF00082 0.637
CLV_PCSK_KEX2_1 94 96 PF00082 0.590
CLV_PCSK_PC1ET2_1 1042 1044 PF00082 0.631
CLV_PCSK_PC1ET2_1 1215 1217 PF00082 0.378
CLV_PCSK_PC1ET2_1 1806 1808 PF00082 0.308
CLV_PCSK_PC1ET2_1 370 372 PF00082 0.579
CLV_PCSK_PC7_1 1802 1808 PF00082 0.308
CLV_PCSK_SKI1_1 1042 1046 PF00082 0.600
CLV_PCSK_SKI1_1 120 124 PF00082 0.613
CLV_PCSK_SKI1_1 1354 1358 PF00082 0.372
CLV_PCSK_SKI1_1 1426 1430 PF00082 0.365
CLV_PCSK_SKI1_1 148 152 PF00082 0.599
CLV_PCSK_SKI1_1 1648 1652 PF00082 0.331
CLV_PCSK_SKI1_1 1680 1684 PF00082 0.322
CLV_PCSK_SKI1_1 1793 1797 PF00082 0.308
CLV_PCSK_SKI1_1 194 198 PF00082 0.578
CLV_PCSK_SKI1_1 556 560 PF00082 0.598
CLV_PCSK_SKI1_1 607 611 PF00082 0.558
CLV_PCSK_SKI1_1 648 652 PF00082 0.597
CLV_PCSK_SKI1_1 733 737 PF00082 0.625
CLV_PCSK_SKI1_1 753 757 PF00082 0.550
CLV_PCSK_SKI1_1 820 824 PF00082 0.555
DEG_APCC_DBOX_1 606 614 PF00400 0.366
DEG_MDM2_SWIB_1 1421 1429 PF02201 0.446
DEG_Nend_Nbox_1 1 3 PF02207 0.382
DEG_ODPH_VHL_1 1295 1307 PF01847 0.447
DOC_CDC14_PxL_1 861 869 PF14671 0.291
DOC_CKS1_1 1362 1367 PF01111 0.513
DOC_CYCLIN_yCln2_LP_2 1359 1365 PF00134 0.409
DOC_CYCLIN_yCln2_LP_2 1377 1383 PF00134 0.180
DOC_CYCLIN_yCln2_LP_2 655 661 PF00134 0.313
DOC_CYCLIN_yCln2_LP_2 70 76 PF00134 0.349
DOC_MAPK_gen_1 1065 1071 PF00069 0.374
DOC_MAPK_gen_1 1087 1095 PF00069 0.353
DOC_MAPK_gen_1 1313 1321 PF00069 0.515
DOC_MAPK_gen_1 1454 1462 PF00069 0.617
DOC_MAPK_gen_1 1680 1689 PF00069 0.508
DOC_MAPK_gen_1 193 199 PF00069 0.390
DOC_MAPK_HePTP_8 702 714 PF00069 0.367
DOC_MAPK_MEF2A_6 1124 1133 PF00069 0.516
DOC_MAPK_MEF2A_6 1315 1323 PF00069 0.505
DOC_MAPK_MEF2A_6 1371 1378 PF00069 0.522
DOC_MAPK_MEF2A_6 380 389 PF00069 0.363
DOC_MAPK_MEF2A_6 705 714 PF00069 0.366
DOC_MAPK_MEF2A_6 909 918 PF00069 0.403
DOC_MAPK_NFAT4_5 1371 1379 PF00069 0.536
DOC_MAPK_RevD_3 1199 1215 PF00069 0.485
DOC_PP1_RVXF_1 1352 1358 PF00149 0.436
DOC_PP1_RVXF_1 139 145 PF00149 0.347
DOC_PP1_RVXF_1 1424 1431 PF00149 0.565
DOC_PP1_RVXF_1 359 365 PF00149 0.340
DOC_PP1_RVXF_1 688 694 PF00149 0.369
DOC_PP2B_LxvP_1 1167 1170 PF13499 0.332
DOC_PP2B_LxvP_1 1184 1187 PF13499 0.230
DOC_PP2B_LxvP_1 158 161 PF13499 0.327
DOC_PP2B_LxvP_1 477 480 PF13499 0.407
DOC_PP4_FxxP_1 1249 1252 PF00568 0.344
DOC_PP4_FxxP_1 6 9 PF00568 0.447
DOC_SPAK_OSR1_1 1150 1154 PF12202 0.408
DOC_SPAK_OSR1_1 1371 1375 PF12202 0.453
DOC_USP7_MATH_1 1024 1028 PF00917 0.536
DOC_USP7_MATH_1 1170 1174 PF00917 0.391
DOC_USP7_MATH_1 1252 1256 PF00917 0.369
DOC_USP7_MATH_1 153 157 PF00917 0.404
DOC_USP7_MATH_1 1710 1714 PF00917 0.591
DOC_USP7_MATH_1 1823 1827 PF00917 0.661
DOC_USP7_MATH_1 1828 1832 PF00917 0.644
DOC_USP7_MATH_1 1863 1867 PF00917 0.746
DOC_USP7_MATH_1 1883 1887 PF00917 0.531
DOC_USP7_MATH_1 421 425 PF00917 0.387
DOC_USP7_MATH_1 511 515 PF00917 0.393
DOC_USP7_MATH_1 746 750 PF00917 0.356
DOC_USP7_MATH_1 789 793 PF00917 0.396
DOC_USP7_MATH_1 877 881 PF00917 0.479
DOC_USP7_MATH_1 99 103 PF00917 0.429
DOC_WW_Pin1_4 1188 1193 PF00397 0.415
DOC_WW_Pin1_4 131 136 PF00397 0.432
DOC_WW_Pin1_4 1361 1366 PF00397 0.496
DOC_WW_Pin1_4 1540 1545 PF00397 0.668
DOC_WW_Pin1_4 1593 1598 PF00397 0.561
DOC_WW_Pin1_4 1720 1725 PF00397 0.508
DOC_WW_Pin1_4 1840 1845 PF00397 0.617
DOC_WW_Pin1_4 1859 1864 PF00397 0.501
DOC_WW_Pin1_4 1869 1874 PF00397 0.766
DOC_WW_Pin1_4 266 271 PF00397 0.418
DOC_WW_Pin1_4 380 385 PF00397 0.376
DOC_WW_Pin1_4 403 408 PF00397 0.421
DOC_WW_Pin1_4 532 537 PF00397 0.284
DOC_WW_Pin1_4 889 894 PF00397 0.415
LIG_14-3-3_CanoR_1 1003 1012 PF00244 0.463
LIG_14-3-3_CanoR_1 1410 1418 PF00244 0.434
LIG_14-3-3_CanoR_1 1447 1457 PF00244 0.584
LIG_14-3-3_CanoR_1 1807 1814 PF00244 0.508
LIG_14-3-3_CanoR_1 361 365 PF00244 0.373
LIG_14-3-3_CanoR_1 437 442 PF00244 0.384
LIG_14-3-3_CanoR_1 475 480 PF00244 0.352
LIG_14-3-3_CanoR_1 493 497 PF00244 0.431
LIG_14-3-3_CanoR_1 50 56 PF00244 0.458
LIG_14-3-3_CanoR_1 607 613 PF00244 0.364
LIG_14-3-3_CanoR_1 733 739 PF00244 0.418
LIG_14-3-3_CanoR_1 753 758 PF00244 0.382
LIG_14-3-3_CanoR_1 814 818 PF00244 0.401
LIG_14-3-3_CanoR_1 872 876 PF00244 0.436
LIG_14-3-3_CanoR_1 879 885 PF00244 0.380
LIG_14-3-3_CanoR_1 891 897 PF00244 0.322
LIG_14-3-3_CanoR_1 909 916 PF00244 0.288
LIG_14-3-3_CanoR_1 925 931 PF00244 0.345
LIG_14-3-3_CanoR_1 955 959 PF00244 0.431
LIG_Actin_WH2_2 1254 1270 PF00022 0.448
LIG_Actin_WH2_2 1834 1849 PF00022 0.602
LIG_AP2alpha_1 351 355 PF02296 0.368
LIG_AP2alpha_2 187 189 PF02296 0.381
LIG_AP2alpha_2 788 790 PF02296 0.373
LIG_APCC_ABBA_1 1631 1636 PF00400 0.508
LIG_APCC_ABBA_1 855 860 PF00400 0.401
LIG_APCC_ABBAyCdc20_2 1675 1681 PF00400 0.508
LIG_BRCT_BRCA1_1 1316 1320 PF00533 0.444
LIG_BRCT_BRCA1_1 1412 1416 PF00533 0.252
LIG_BRCT_BRCA1_1 1769 1773 PF00533 0.561
LIG_BRCT_BRCA1_1 1831 1835 PF00533 0.676
LIG_BRCT_BRCA1_1 225 229 PF00533 0.396
LIG_BRCT_BRCA1_2 225 231 PF00533 0.291
LIG_CaM_IQ_9 1448 1463 PF13499 0.618
LIG_Clathr_ClatBox_1 1551 1555 PF01394 0.664
LIG_Clathr_ClatBox_1 1632 1636 PF01394 0.531
LIG_CtBP_PxDLS_1 881 887 PF00389 0.290
LIG_deltaCOP1_diTrp_1 1089 1096 PF00928 0.391
LIG_deltaCOP1_diTrp_1 1758 1765 PF00928 0.561
LIG_deltaCOP1_diTrp_1 1851 1858 PF00928 0.662
LIG_deltaCOP1_diTrp_1 200 211 PF00928 0.392
LIG_deltaCOP1_diTrp_1 847 855 PF00928 0.372
LIG_EH1_1 1238 1246 PF00400 0.391
LIG_FHA_1 1102 1108 PF00498 0.416
LIG_FHA_1 1270 1276 PF00498 0.384
LIG_FHA_1 1339 1345 PF00498 0.224
LIG_FHA_1 1436 1442 PF00498 0.571
LIG_FHA_1 1496 1502 PF00498 0.566
LIG_FHA_1 153 159 PF00498 0.397
LIG_FHA_1 1571 1577 PF00498 0.508
LIG_FHA_1 1628 1634 PF00498 0.551
LIG_FHA_1 1642 1648 PF00498 0.481
LIG_FHA_1 1652 1658 PF00498 0.504
LIG_FHA_1 1660 1666 PF00498 0.426
LIG_FHA_1 1776 1782 PF00498 0.508
LIG_FHA_1 1869 1875 PF00498 0.742
LIG_FHA_1 331 337 PF00498 0.399
LIG_FHA_1 389 395 PF00498 0.315
LIG_FHA_1 472 478 PF00498 0.376
LIG_FHA_1 486 492 PF00498 0.414
LIG_FHA_1 507 513 PF00498 0.333
LIG_FHA_1 52 58 PF00498 0.372
LIG_FHA_1 580 586 PF00498 0.432
LIG_FHA_1 599 605 PF00498 0.254
LIG_FHA_1 642 648 PF00498 0.292
LIG_FHA_1 760 766 PF00498 0.382
LIG_FHA_1 78 84 PF00498 0.352
LIG_FHA_1 852 858 PF00498 0.402
LIG_FHA_1 909 915 PF00498 0.370
LIG_FHA_1 919 925 PF00498 0.346
LIG_FHA_1 927 933 PF00498 0.302
LIG_FHA_1 946 952 PF00498 0.415
LIG_FHA_2 1051 1057 PF00498 0.429
LIG_FHA_2 1084 1090 PF00498 0.414
LIG_FHA_2 1132 1138 PF00498 0.565
LIG_FHA_2 1508 1514 PF00498 0.615
LIG_FHA_2 1624 1630 PF00498 0.531
LIG_FHA_2 1737 1743 PF00498 0.508
LIG_FHA_2 1747 1753 PF00498 0.508
LIG_FHA_2 225 231 PF00498 0.428
LIG_FHA_2 327 333 PF00498 0.385
LIG_FHA_2 771 777 PF00498 0.387
LIG_FHA_2 915 921 PF00498 0.384
LIG_GBD_Chelix_1 1174 1182 PF00786 0.598
LIG_Integrin_RGD_1 774 776 PF01839 0.504
LIG_LIR_Apic_2 146 152 PF02991 0.374
LIG_LIR_Apic_2 1723 1729 PF02991 0.508
LIG_LIR_Apic_2 5 9 PF02991 0.445
LIG_LIR_Apic_2 739 744 PF02991 0.382
LIG_LIR_Gen_1 1089 1099 PF02991 0.321
LIG_LIR_Gen_1 1104 1111 PF02991 0.264
LIG_LIR_Gen_1 1132 1143 PF02991 0.547
LIG_LIR_Gen_1 1147 1156 PF02991 0.289
LIG_LIR_Gen_1 1272 1280 PF02991 0.384
LIG_LIR_Gen_1 1288 1297 PF02991 0.379
LIG_LIR_Gen_1 1317 1327 PF02991 0.485
LIG_LIR_Gen_1 1419 1429 PF02991 0.392
LIG_LIR_Gen_1 166 176 PF02991 0.374
LIG_LIR_Gen_1 1662 1671 PF02991 0.508
LIG_LIR_Gen_1 1763 1773 PF02991 0.508
LIG_LIR_Gen_1 1832 1842 PF02991 0.670
LIG_LIR_Gen_1 195 202 PF02991 0.436
LIG_LIR_Gen_1 242 252 PF02991 0.394
LIG_LIR_Gen_1 286 295 PF02991 0.398
LIG_LIR_Gen_1 383 394 PF02991 0.333
LIG_LIR_Gen_1 462 472 PF02991 0.420
LIG_LIR_Gen_1 547 558 PF02991 0.372
LIG_LIR_Gen_1 700 706 PF02991 0.356
LIG_LIR_Gen_1 845 855 PF02991 0.387
LIG_LIR_LC3C_4 946 951 PF02991 0.416
LIG_LIR_Nem_3 1089 1095 PF02991 0.321
LIG_LIR_Nem_3 1104 1108 PF02991 0.264
LIG_LIR_Nem_3 1132 1138 PF02991 0.543
LIG_LIR_Nem_3 1139 1143 PF02991 0.503
LIG_LIR_Nem_3 1147 1151 PF02991 0.296
LIG_LIR_Nem_3 1209 1213 PF02991 0.376
LIG_LIR_Nem_3 1279 1284 PF02991 0.346
LIG_LIR_Nem_3 1317 1323 PF02991 0.460
LIG_LIR_Nem_3 1330 1336 PF02991 0.315
LIG_LIR_Nem_3 1364 1369 PF02991 0.504
LIG_LIR_Nem_3 1406 1412 PF02991 0.287
LIG_LIR_Nem_3 1419 1424 PF02991 0.311
LIG_LIR_Nem_3 1459 1465 PF02991 0.570
LIG_LIR_Nem_3 1570 1574 PF02991 0.512
LIG_LIR_Nem_3 166 171 PF02991 0.366
LIG_LIR_Nem_3 1662 1666 PF02991 0.508
LIG_LIR_Nem_3 1763 1768 PF02991 0.508
LIG_LIR_Nem_3 1832 1838 PF02991 0.681
LIG_LIR_Nem_3 195 199 PF02991 0.433
LIG_LIR_Nem_3 242 247 PF02991 0.361
LIG_LIR_Nem_3 277 283 PF02991 0.324
LIG_LIR_Nem_3 286 292 PF02991 0.292
LIG_LIR_Nem_3 38 43 PF02991 0.359
LIG_LIR_Nem_3 383 389 PF02991 0.287
LIG_LIR_Nem_3 462 467 PF02991 0.431
LIG_LIR_Nem_3 547 553 PF02991 0.372
LIG_LIR_Nem_3 700 704 PF02991 0.356
LIG_LIR_Nem_3 788 793 PF02991 0.261
LIG_LIR_Nem_3 845 851 PF02991 0.356
LIG_LIR_Nem_3 854 858 PF02991 0.346
LIG_LIR_Nem_3 933 937 PF02991 0.268
LIG_MYND_1 1844 1848 PF01753 0.475
LIG_NRBOX 1035 1041 PF00104 0.382
LIG_NRBOX 693 699 PF00104 0.315
LIG_PCNA_yPIPBox_3 955 963 PF02747 0.467
LIG_Pex14_1 1092 1096 PF04695 0.446
LIG_Pex14_1 1112 1116 PF04695 0.357
LIG_Pex14_1 1206 1210 PF04695 0.444
LIG_Pex14_1 1219 1223 PF04695 0.564
LIG_Pex14_1 1333 1337 PF04695 0.309
LIG_Pex14_1 1761 1765 PF04695 0.508
LIG_Pex14_2 1202 1206 PF04695 0.364
LIG_Pex14_2 1345 1349 PF04695 0.444
LIG_Pex14_2 1357 1361 PF04695 0.455
LIG_Pex14_2 1381 1385 PF04695 0.252
LIG_Pex14_2 1421 1425 PF04695 0.425
LIG_Pex14_2 351 355 PF04695 0.344
LIG_Pex14_2 364 368 PF04695 0.365
LIG_PTB_Apo_2 1243 1250 PF02174 0.444
LIG_PTB_Apo_2 1343 1350 PF02174 0.395
LIG_PTB_Apo_2 676 683 PF02174 0.415
LIG_REV1ctd_RIR_1 187 198 PF16727 0.377
LIG_SH2_CRK 1078 1082 PF00017 0.390
LIG_SH2_CRK 1140 1144 PF00017 0.537
LIG_SH2_CRK 1239 1243 PF00017 0.429
LIG_SH2_CRK 1337 1341 PF00017 0.362
LIG_SH2_CRK 1366 1370 PF00017 0.501
LIG_SH2_CRK 1390 1394 PF00017 0.428
LIG_SH2_CRK 1571 1575 PF00017 0.508
LIG_SH2_CRK 244 248 PF00017 0.392
LIG_SH2_CRK 40 44 PF00017 0.361
LIG_SH2_CRK 464 468 PF00017 0.426
LIG_SH2_CRK 505 509 PF00017 0.362
LIG_SH2_CRK 550 554 PF00017 0.371
LIG_SH2_CRK 741 745 PF00017 0.414
LIG_SH2_CRK 934 938 PF00017 0.353
LIG_SH2_GRB2like 1527 1530 PF00017 0.738
LIG_SH2_GRB2like 1589 1592 PF00017 0.551
LIG_SH2_NCK_1 1078 1082 PF00017 0.390
LIG_SH2_NCK_1 1140 1144 PF00017 0.561
LIG_SH2_NCK_1 1337 1341 PF00017 0.225
LIG_SH2_NCK_1 298 302 PF00017 0.439
LIG_SH2_NCK_1 464 468 PF00017 0.426
LIG_SH2_PTP2 1589 1592 PF00017 0.531
LIG_SH2_PTP2 386 389 PF00017 0.339
LIG_SH2_SRC 1078 1081 PF00017 0.419
LIG_SH2_SRC 1589 1592 PF00017 0.551
LIG_SH2_SRC 578 581 PF00017 0.276
LIG_SH2_STAP1 1661 1665 PF00017 0.508
LIG_SH2_STAP1 1769 1773 PF00017 0.508
LIG_SH2_STAP1 472 476 PF00017 0.384
LIG_SH2_STAT3 1661 1664 PF00017 0.508
LIG_SH2_STAT5 1114 1117 PF00017 0.594
LIG_SH2_STAT5 1203 1206 PF00017 0.420
LIG_SH2_STAT5 1212 1215 PF00017 0.410
LIG_SH2_STAT5 1223 1226 PF00017 0.573
LIG_SH2_STAT5 1230 1233 PF00017 0.435
LIG_SH2_STAT5 1239 1242 PF00017 0.269
LIG_SH2_STAT5 1384 1387 PF00017 0.403
LIG_SH2_STAT5 1399 1402 PF00017 0.233
LIG_SH2_STAT5 1487 1490 PF00017 0.579
LIG_SH2_STAT5 1589 1592 PF00017 0.508
LIG_SH2_STAT5 1621 1624 PF00017 0.516
LIG_SH2_STAT5 1661 1664 PF00017 0.504
LIG_SH2_STAT5 1671 1674 PF00017 0.514
LIG_SH2_STAT5 1774 1777 PF00017 0.508
LIG_SH2_STAT5 244 247 PF00017 0.348
LIG_SH2_STAT5 280 283 PF00017 0.386
LIG_SH2_STAT5 386 389 PF00017 0.352
LIG_SH2_STAT5 445 448 PF00017 0.373
LIG_SH2_STAT5 808 811 PF00017 0.404
LIG_SH2_STAT5 889 892 PF00017 0.376
LIG_SH2_STAT5 992 995 PF00017 0.384
LIG_SH3_2 1362 1367 PF14604 0.592
LIG_SH3_3 1018 1024 PF00018 0.517
LIG_SH3_3 1162 1168 PF00018 0.318
LIG_SH3_3 1291 1297 PF00018 0.444
LIG_SH3_3 1359 1365 PF00018 0.445
LIG_SH3_3 158 164 PF00018 0.288
LIG_SH3_3 1718 1724 PF00018 0.531
LIG_SH3_3 1779 1785 PF00018 0.508
LIG_SH3_3 1838 1844 PF00018 0.598
LIG_SH3_3 1877 1883 PF00018 0.717
LIG_SH3_3 278 284 PF00018 0.433
LIG_SH3_3 297 303 PF00018 0.396
LIG_SH3_3 56 62 PF00018 0.419
LIG_SH3_3 791 797 PF00018 0.419
LIG_SH3_3 804 810 PF00018 0.397
LIG_SH3_3 824 830 PF00018 0.360
LIG_SH3_3 887 893 PF00018 0.422
LIG_SH3_3 948 954 PF00018 0.416
LIG_SUMO_SIM_anti_2 1240 1246 PF11976 0.444
LIG_SUMO_SIM_anti_2 563 568 PF11976 0.408
LIG_SUMO_SIM_anti_2 608 614 PF11976 0.367
LIG_SUMO_SIM_anti_2 657 663 PF11976 0.369
LIG_SUMO_SIM_anti_2 66 72 PF11976 0.364
LIG_SUMO_SIM_anti_2 899 906 PF11976 0.396
LIG_SUMO_SIM_par_1 1390 1396 PF11976 0.441
LIG_SUMO_SIM_par_1 1550 1556 PF11976 0.651
LIG_SUMO_SIM_par_1 390 395 PF11976 0.324
LIG_SUMO_SIM_par_1 508 514 PF11976 0.347
LIG_SUMO_SIM_par_1 580 587 PF11976 0.453
LIG_SUMO_SIM_par_1 600 606 PF11976 0.339
LIG_SUMO_SIM_par_1 911 921 PF11976 0.393
LIG_SUMO_SIM_par_1 928 933 PF11976 0.292
LIG_SUMO_SIM_par_1 946 953 PF11976 0.370
LIG_SUMO_SIM_par_1 961 968 PF11976 0.436
LIG_TRAF2_1 1553 1556 PF00917 0.625
LIG_TYR_ITIM 1138 1143 PF00017 0.446
LIG_TYR_ITIM 1388 1393 PF00017 0.420
LIG_TYR_ITIM 1587 1592 PF00017 0.369
LIG_TYR_ITIM 932 937 PF00017 0.433
LIG_TYR_ITSM 1362 1369 PF00017 0.346
LIG_TYR_ITSM 460 467 PF00017 0.541
LIG_UBA3_1 1207 1215 PF00899 0.460
LIG_UBA3_1 1231 1237 PF00899 0.308
LIG_WRC_WIRS_1 1102 1107 PF05994 0.485
LIG_WRC_WIRS_1 1207 1212 PF05994 0.393
LIG_WRC_WIRS_1 1286 1291 PF05994 0.444
LIG_WRC_WIRS_1 1557 1562 PF05994 0.508
LIG_WRC_WIRS_1 1660 1665 PF05994 0.485
LIG_WRC_WIRS_1 1835 1840 PF05994 0.567
LIG_WRC_WIRS_1 365 370 PF05994 0.463
LIG_WRC_WIRS_1 760 765 PF05994 0.419
MOD_CDK_SPxK_1 1361 1367 PF00069 0.487
MOD_CDK_SPxK_1 266 272 PF00069 0.518
MOD_CDK_SPxxK_3 1188 1195 PF00069 0.513
MOD_CDK_SPxxK_3 1840 1847 PF00069 0.559
MOD_CK1_1 1285 1291 PF00069 0.427
MOD_CK1_1 1299 1305 PF00069 0.349
MOD_CK1_1 1520 1526 PF00069 0.634
MOD_CK1_1 1570 1576 PF00069 0.369
MOD_CK1_1 1596 1602 PF00069 0.310
MOD_CK1_1 1642 1648 PF00069 0.369
MOD_CK1_1 1837 1843 PF00069 0.510
MOD_CK1_1 1859 1865 PF00069 0.479
MOD_CK1_1 1886 1892 PF00069 0.705
MOD_CK1_1 192 198 PF00069 0.444
MOD_CK1_1 357 363 PF00069 0.335
MOD_CK1_1 449 455 PF00069 0.379
MOD_CK1_1 519 525 PF00069 0.434
MOD_CK1_1 53 59 PF00069 0.526
MOD_CK1_1 581 587 PF00069 0.548
MOD_CK1_1 60 66 PF00069 0.476
MOD_CK1_1 608 614 PF00069 0.385
MOD_CK1_1 739 745 PF00069 0.439
MOD_CK1_1 749 755 PF00069 0.346
MOD_CK1_1 77 83 PF00069 0.313
MOD_CK1_1 792 798 PF00069 0.448
MOD_CK1_1 880 886 PF00069 0.431
MOD_CK1_1 892 898 PF00069 0.495
MOD_CK1_1 977 983 PF00069 0.462
MOD_CK2_1 1131 1137 PF00069 0.377
MOD_CK2_1 126 132 PF00069 0.434
MOD_CK2_1 1550 1556 PF00069 0.544
MOD_CK2_1 163 169 PF00069 0.459
MOD_CK2_1 1746 1752 PF00069 0.369
MOD_CK2_1 1806 1812 PF00069 0.369
MOD_CK2_1 1823 1829 PF00069 0.503
MOD_CK2_1 1862 1868 PF00069 0.669
MOD_CK2_1 880 886 PF00069 0.377
MOD_CMANNOS 115 118 PF00535 0.466
MOD_Cter_Amidation 526 529 PF01082 0.541
MOD_GlcNHglycan 1005 1008 PF01048 0.545
MOD_GlcNHglycan 1025 1029 PF01048 0.350
MOD_GlcNHglycan 1140 1143 PF01048 0.444
MOD_GlcNHglycan 12 16 PF01048 0.575
MOD_GlcNHglycan 1412 1415 PF01048 0.377
MOD_GlcNHglycan 145 148 PF01048 0.476
MOD_GlcNHglycan 1507 1510 PF01048 0.520
MOD_GlcNHglycan 155 158 PF01048 0.408
MOD_GlcNHglycan 1769 1772 PF01048 0.401
MOD_GlcNHglycan 1808 1811 PF01048 0.425
MOD_GlcNHglycan 1820 1823 PF01048 0.473
MOD_GlcNHglycan 250 253 PF01048 0.441
MOD_GlcNHglycan 419 422 PF01048 0.505
MOD_GlcNHglycan 448 451 PF01048 0.376
MOD_GlcNHglycan 453 456 PF01048 0.373
MOD_GlcNHglycan 524 527 PF01048 0.535
MOD_GlcNHglycan 586 589 PF01048 0.580
MOD_GlcNHglycan 619 622 PF01048 0.373
MOD_GlcNHglycan 623 626 PF01048 0.371
MOD_GlcNHglycan 685 688 PF01048 0.439
MOD_GlcNHglycan 724 727 PF01048 0.486
MOD_GlcNHglycan 738 741 PF01048 0.463
MOD_GlcNHglycan 794 797 PF01048 0.418
MOD_GlcNHglycan 817 820 PF01048 0.520
MOD_GlcNHglycan 835 838 PF01048 0.342
MOD_GlcNHglycan 843 847 PF01048 0.400
MOD_GlcNHglycan 873 876 PF01048 0.587
MOD_GlcNHglycan 879 882 PF01048 0.557
MOD_GlcNHglycan 976 979 PF01048 0.514
MOD_GSK3_1 1215 1222 PF00069 0.446
MOD_GSK3_1 1295 1302 PF00069 0.401
MOD_GSK3_1 1393 1400 PF00069 0.468
MOD_GSK3_1 1428 1435 PF00069 0.454
MOD_GSK3_1 1513 1520 PF00069 0.499
MOD_GSK3_1 1623 1630 PF00069 0.444
MOD_GSK3_1 1716 1723 PF00069 0.369
MOD_GSK3_1 1742 1749 PF00069 0.369
MOD_GSK3_1 1836 1843 PF00069 0.573
MOD_GSK3_1 1858 1865 PF00069 0.677
MOD_GSK3_1 1882 1889 PF00069 0.709
MOD_GSK3_1 215 222 PF00069 0.483
MOD_GSK3_1 242 249 PF00069 0.427
MOD_GSK3_1 319 326 PF00069 0.483
MOD_GSK3_1 330 337 PF00069 0.513
MOD_GSK3_1 356 363 PF00069 0.383
MOD_GSK3_1 417 424 PF00069 0.502
MOD_GSK3_1 437 444 PF00069 0.188
MOD_GSK3_1 451 458 PF00069 0.340
MOD_GSK3_1 471 478 PF00069 0.434
MOD_GSK3_1 506 513 PF00069 0.450
MOD_GSK3_1 518 525 PF00069 0.410
MOD_GSK3_1 53 60 PF00069 0.536
MOD_GSK3_1 570 577 PF00069 0.443
MOD_GSK3_1 589 596 PF00069 0.315
MOD_GSK3_1 617 624 PF00069 0.460
MOD_GSK3_1 637 644 PF00069 0.380
MOD_GSK3_1 700 707 PF00069 0.332
MOD_GSK3_1 74 81 PF00069 0.426
MOD_GSK3_1 749 756 PF00069 0.412
MOD_GSK3_1 809 816 PF00069 0.511
MOD_GSK3_1 899 906 PF00069 0.480
MOD_GSK3_1 910 917 PF00069 0.503
MOD_GSK3_1 926 933 PF00069 0.442
MOD_LATS_1 1001 1007 PF00433 0.564
MOD_N-GLC_1 109 114 PF02516 0.489
MOD_N-GLC_1 1710 1715 PF02516 0.401
MOD_N-GLC_1 1874 1879 PF02516 0.750
MOD_N-GLC_1 1883 1888 PF02516 0.653
MOD_N-GLC_1 1892 1897 PF02516 0.587
MOD_N-GLC_1 326 331 PF02516 0.424
MOD_N-GLC_1 403 408 PF02516 0.532
MOD_N-GLC_1 441 446 PF02516 0.372
MOD_N-GLC_1 459 464 PF02516 0.499
MOD_N-GLC_1 506 511 PF02516 0.438
MOD_N-GLC_1 570 575 PF02516 0.438
MOD_N-GLC_1 66 71 PF02516 0.441
MOD_N-GLC_1 722 727 PF02516 0.494
MOD_N-GLC_1 753 758 PF02516 0.365
MOD_N-GLC_2 181 183 PF02516 0.511
MOD_NEK2_1 109 114 PF00069 0.449
MOD_NEK2_1 1129 1134 PF00069 0.375
MOD_NEK2_1 1138 1143 PF00069 0.371
MOD_NEK2_1 1156 1161 PF00069 0.221
MOD_NEK2_1 1253 1258 PF00069 0.441
MOD_NEK2_1 126 131 PF00069 0.376
MOD_NEK2_1 1327 1332 PF00069 0.395
MOD_NEK2_1 1393 1398 PF00069 0.487
MOD_NEK2_1 1416 1421 PF00069 0.422
MOD_NEK2_1 1446 1451 PF00069 0.488
MOD_NEK2_1 1505 1510 PF00069 0.458
MOD_NEK2_1 1700 1705 PF00069 0.369
MOD_NEK2_1 1836 1841 PF00069 0.594
MOD_NEK2_1 1858 1863 PF00069 0.604
MOD_NEK2_1 1874 1879 PF00069 0.565
MOD_NEK2_1 189 194 PF00069 0.428
MOD_NEK2_1 319 324 PF00069 0.489
MOD_NEK2_1 354 359 PF00069 0.376
MOD_NEK2_1 364 369 PF00069 0.382
MOD_NEK2_1 388 393 PF00069 0.524
MOD_NEK2_1 417 422 PF00069 0.450
MOD_NEK2_1 441 446 PF00069 0.372
MOD_NEK2_1 510 515 PF00069 0.422
MOD_NEK2_1 598 603 PF00069 0.376
MOD_NEK2_1 641 646 PF00069 0.429
MOD_NEK2_1 682 687 PF00069 0.419
MOD_NEK2_1 731 736 PF00069 0.536
MOD_NEK2_1 815 820 PF00069 0.458
MOD_NEK2_1 851 856 PF00069 0.499
MOD_NEK2_1 903 908 PF00069 0.490
MOD_NEK2_1 930 935 PF00069 0.416
MOD_NEK2_2 1026 1031 PF00069 0.658
MOD_NEK2_2 1101 1106 PF00069 0.401
MOD_NEK2_2 224 229 PF00069 0.343
MOD_NEK2_2 288 293 PF00069 0.441
MOD_NEK2_2 35 40 PF00069 0.469
MOD_NEK2_2 759 764 PF00069 0.449
MOD_PIKK_1 126 132 PF00454 0.316
MOD_PIKK_1 1400 1406 PF00454 0.452
MOD_PIKK_1 1428 1434 PF00454 0.424
MOD_PIKK_1 1448 1454 PF00454 0.187
MOD_PIKK_1 1710 1716 PF00454 0.444
MOD_PIKK_1 204 210 PF00454 0.511
MOD_PIKK_1 343 349 PF00454 0.437
MOD_PIKK_1 466 472 PF00454 0.439
MOD_PIKK_1 809 815 PF00454 0.458
MOD_PK_1 475 481 PF00069 0.491
MOD_PKA_1 1215 1221 PF00069 0.468
MOD_PKA_1 1648 1654 PF00069 0.444
MOD_PKA_1 1806 1812 PF00069 0.369
MOD_PKA_2 1215 1221 PF00069 0.460
MOD_PKA_2 1314 1320 PF00069 0.384
MOD_PKA_2 1446 1452 PF00069 0.485
MOD_PKA_2 1806 1812 PF00069 0.384
MOD_PKA_2 254 260 PF00069 0.508
MOD_PKA_2 35 41 PF00069 0.422
MOD_PKA_2 360 366 PF00069 0.454
MOD_PKA_2 455 461 PF00069 0.496
MOD_PKA_2 492 498 PF00069 0.546
MOD_PKA_2 704 710 PF00069 0.471
MOD_PKA_2 813 819 PF00069 0.440
MOD_PKA_2 871 877 PF00069 0.589
MOD_PKA_2 908 914 PF00069 0.467
MOD_PKA_2 954 960 PF00069 0.540
MOD_PKB_1 1493 1501 PF00069 0.487
MOD_Plk_1 1136 1142 PF00069 0.372
MOD_Plk_1 1439 1445 PF00069 0.488
MOD_Plk_1 1710 1716 PF00069 0.429
MOD_Plk_1 1883 1889 PF00069 0.674
MOD_Plk_1 28 34 PF00069 0.440
MOD_Plk_1 441 447 PF00069 0.387
MOD_Plk_1 485 491 PF00069 0.509
MOD_Plk_1 506 512 PF00069 0.435
MOD_Plk_1 546 552 PF00069 0.460
MOD_Plk_1 573 579 PF00069 0.532
MOD_Plk_1 605 611 PF00069 0.407
MOD_Plk_1 66 72 PF00069 0.442
MOD_Plk_1 670 676 PF00069 0.484
MOD_Plk_1 753 759 PF00069 0.366
MOD_Plk_1 899 905 PF00069 0.477
MOD_Plk_2-3 574 580 PF00069 0.505
MOD_Plk_4 1091 1097 PF00069 0.436
MOD_Plk_4 1107 1113 PF00069 0.313
MOD_Plk_4 1215 1221 PF00069 0.468
MOD_Plk_4 1237 1243 PF00069 0.412
MOD_Plk_4 1253 1259 PF00069 0.275
MOD_Plk_4 1262 1268 PF00069 0.336
MOD_Plk_4 1296 1302 PF00069 0.466
MOD_Plk_4 1327 1333 PF00069 0.412
MOD_Plk_4 1547 1553 PF00069 0.571
MOD_Plk_4 1627 1633 PF00069 0.432
MOD_Plk_4 1642 1648 PF00069 0.298
MOD_Plk_4 1716 1722 PF00069 0.369
MOD_Plk_4 1746 1752 PF00069 0.369
MOD_Plk_4 1837 1843 PF00069 0.348
MOD_Plk_4 192 198 PF00069 0.410
MOD_Plk_4 224 230 PF00069 0.467
MOD_Plk_4 319 325 PF00069 0.493
MOD_Plk_4 35 41 PF00069 0.421
MOD_Plk_4 360 366 PF00069 0.440
MOD_Plk_4 388 394 PF00069 0.385
MOD_Plk_4 441 447 PF00069 0.362
MOD_Plk_4 519 525 PF00069 0.489
MOD_Plk_4 560 566 PF00069 0.369
MOD_Plk_4 586 592 PF00069 0.515
MOD_Plk_4 598 604 PF00069 0.400
MOD_Plk_4 608 614 PF00069 0.287
MOD_Plk_4 66 72 PF00069 0.394
MOD_Plk_4 670 676 PF00069 0.465
MOD_Plk_4 689 695 PF00069 0.235
MOD_Plk_4 74 80 PF00069 0.403
MOD_Plk_4 746 752 PF00069 0.405
MOD_Plk_4 753 759 PF00069 0.327
MOD_Plk_4 789 795 PF00069 0.527
MOD_Plk_4 88 94 PF00069 0.435
MOD_Plk_4 892 898 PF00069 0.406
MOD_Plk_4 899 905 PF00069 0.389
MOD_Plk_4 918 924 PF00069 0.361
MOD_Plk_4 926 932 PF00069 0.415
MOD_Plk_4 945 951 PF00069 0.457
MOD_Plk_4 954 960 PF00069 0.477
MOD_ProDKin_1 1188 1194 PF00069 0.516
MOD_ProDKin_1 131 137 PF00069 0.544
MOD_ProDKin_1 1361 1367 PF00069 0.352
MOD_ProDKin_1 1540 1546 PF00069 0.587
MOD_ProDKin_1 1593 1599 PF00069 0.444
MOD_ProDKin_1 1720 1726 PF00069 0.369
MOD_ProDKin_1 1840 1846 PF00069 0.520
MOD_ProDKin_1 1859 1865 PF00069 0.363
MOD_ProDKin_1 1869 1875 PF00069 0.732
MOD_ProDKin_1 266 272 PF00069 0.518
MOD_ProDKin_1 380 386 PF00069 0.466
MOD_ProDKin_1 403 409 PF00069 0.526
MOD_ProDKin_1 532 538 PF00069 0.336
MOD_ProDKin_1 889 895 PF00069 0.518
MOD_SUMO_for_1 1460 1463 PF00179 0.456
MOD_SUMO_for_1 1682 1685 PF00179 0.369
MOD_SUMO_for_1 840 843 PF00179 0.554
MOD_SUMO_for_1 965 968 PF00179 0.504
MOD_SUMO_rev_2 412 418 PF00179 0.508
TRG_DiLeu_BaEn_4 605 611 PF01217 0.474
TRG_DiLeu_BaLyEn_6 627 632 PF01217 0.464
TRG_DiLeu_BaLyEn_6 693 698 PF01217 0.454
TRG_ENDOCYTIC_2 1140 1143 PF00928 0.362
TRG_ENDOCYTIC_2 1239 1242 PF00928 0.429
TRG_ENDOCYTIC_2 1273 1276 PF00928 0.448
TRG_ENDOCYTIC_2 1366 1369 PF00928 0.346
TRG_ENDOCYTIC_2 1384 1387 PF00928 0.344
TRG_ENDOCYTIC_2 1390 1393 PF00928 0.337
TRG_ENDOCYTIC_2 1571 1574 PF00928 0.369
TRG_ENDOCYTIC_2 1589 1592 PF00928 0.369
TRG_ENDOCYTIC_2 1769 1772 PF00928 0.369
TRG_ENDOCYTIC_2 244 247 PF00928 0.489
TRG_ENDOCYTIC_2 386 389 PF00928 0.413
TRG_ENDOCYTIC_2 40 43 PF00928 0.443
TRG_ENDOCYTIC_2 464 467 PF00928 0.537
TRG_ENDOCYTIC_2 484 487 PF00928 0.373
TRG_ENDOCYTIC_2 505 508 PF00928 0.422
TRG_ENDOCYTIC_2 550 553 PF00928 0.456
TRG_ENDOCYTIC_2 721 724 PF00928 0.511
TRG_ENDOCYTIC_2 934 937 PF00928 0.433
TRG_ER_diArg_1 1040 1043 PF00400 0.425
TRG_ER_diArg_1 118 120 PF00400 0.505
TRG_ER_diArg_1 1224 1227 PF00400 0.377
TRG_ER_diArg_1 1312 1315 PF00400 0.404
TRG_ER_diArg_1 1453 1456 PF00400 0.425
TRG_ER_diArg_1 1482 1485 PF00400 0.427
TRG_ER_diArg_1 236 239 PF00400 0.433
TRG_ER_diArg_1 436 439 PF00400 0.493
TRG_ER_diArg_1 93 95 PF00400 0.559
TRG_ER_diLys_1 1896 1899 PF00400 0.577
TRG_NES_CRM1_1 1474 1489 PF08389 0.546
TRG_NES_CRM1_1 1598 1612 PF08389 0.444
TRG_NES_CRM1_1 486 499 PF08389 0.488
TRG_NLS_Bipartite_1 1197 1218 PF00514 0.466
TRG_Pf-PMV_PEXEL_1 556 560 PF00026 0.379
TRG_Pf-PMV_PEXEL_1 630 634 PF00026 0.459
TRG_Pf-PMV_PEXEL_1 696 700 PF00026 0.494
TRG_Pf-PMV_PEXEL_1 960 964 PF00026 0.575

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HYY7 Leptomonas seymouri 68% 100%
A0A1X0P1C9 Trypanosomatidae 37% 100%
A0A3S7X3R8 Leishmania donovani 94% 100%
A0A422P0W2 Trypanosoma rangeli 30% 100%
A4HIN9 Leishmania braziliensis 83% 100%
A4I5Y6 Leishmania infantum 94% 100%
E9B179 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
V5BSF9 Trypanosoma cruzi 37% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS