BAR domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q6V7_LEIMA

TriTrypDb:

LmjF.30.3320 , LMJLV39_300042000 , LMJSD75_300041200

Length:

358

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6V7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6V7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	343	347	PF00656	0.707
CLV_NRD_NRD_1	133	135	PF00675	0.407
CLV_NRD_NRD_1	9	11	PF00675	0.463
CLV_PCSK_KEX2_1	133	135	PF00082	0.407
CLV_PCSK_KEX2_1	9	11	PF00082	0.463
CLV_PCSK_SKI1_1	106	110	PF00082	0.434
CLV_PCSK_SKI1_1	156	160	PF00082	0.500
CLV_PCSK_SKI1_1	199	203	PF00082	0.382
CLV_Separin_Metazoa	114	118	PF03568	0.390
DEG_APCC_DBOX_1	198	206	PF00400	0.389
DEG_COP1_1	71	79	PF00400	0.446
DEG_Nend_UBRbox_2	1	3	PF02207	0.560
DOC_CDC14_PxL_1	231	239	PF14671	0.461
DOC_CDC14_PxL_1	73	81	PF14671	0.444
DOC_CKS1_1	248	253	PF01111	0.502
DOC_MAPK_DCC_7	333	341	PF00069	0.540
DOC_MAPK_MEF2A_6	333	341	PF00069	0.540
DOC_USP7_MATH_1	184	188	PF00917	0.394
DOC_USP7_MATH_1	246	250	PF00917	0.482
DOC_USP7_MATH_1	253	257	PF00917	0.636
DOC_USP7_MATH_1	279	283	PF00917	0.681
DOC_USP7_MATH_1	326	330	PF00917	0.669
DOC_USP7_MATH_1	80	84	PF00917	0.429
DOC_WW_Pin1_4	150	155	PF00397	0.454
DOC_WW_Pin1_4	22	27	PF00397	0.624
DOC_WW_Pin1_4	247	252	PF00397	0.499
DOC_WW_Pin1_4	268	273	PF00397	0.622
DOC_WW_Pin1_4	283	288	PF00397	0.589
DOC_WW_Pin1_4	301	306	PF00397	0.623
DOC_WW_Pin1_4	309	314	PF00397	0.659
LIG_14-3-3_CanoR_1	177	185	PF00244	0.381
LIG_14-3-3_CanoR_1	199	208	PF00244	0.384
LIG_14-3-3_CanoR_1	30	38	PF00244	0.497
LIG_14-3-3_CanoR_1	9	18	PF00244	0.480
LIG_BRCT_BRCA1_1	186	190	PF00533	0.464
LIG_BRCT_BRCA1_1	215	219	PF00533	0.392
LIG_CtBP_PxDLS_1	26	30	PF00389	0.550
LIG_deltaCOP1_diTrp_1	169	176	PF00928	0.405
LIG_eIF4E_1	283	289	PF01652	0.566
LIG_EVH1_1	242	246	PF00568	0.576
LIG_FHA_1	10	16	PF00498	0.476
LIG_FHA_1	202	208	PF00498	0.415
LIG_FHA_1	262	268	PF00498	0.605
LIG_FHA_1	284	290	PF00498	0.558
LIG_FHA_2	310	316	PF00498	0.641
LIG_FHA_2	341	347	PF00498	0.658
LIG_FHA_2	41	47	PF00498	0.571
LIG_FHA_2	63	69	PF00498	0.408
LIG_FHA_2	98	104	PF00498	0.410
LIG_LIR_Apic_2	349	355	PF02991	0.608
LIG_LIR_Gen_1	110	120	PF02991	0.391
LIG_LIR_Gen_1	139	147	PF02991	0.384
LIG_LIR_Gen_1	157	162	PF02991	0.448
LIG_LIR_Gen_1	210	219	PF02991	0.419
LIG_LIR_Nem_3	110	116	PF02991	0.400
LIG_LIR_Nem_3	139	143	PF02991	0.377
LIG_LIR_Nem_3	157	161	PF02991	0.450
LIG_LIR_Nem_3	210	214	PF02991	0.418
LIG_LIR_Nem_3	220	226	PF02991	0.528
LIG_LIR_Nem_3	329	334	PF02991	0.592
LIG_LIR_Nem_3	71	76	PF02991	0.447
LIG_MYND_1	235	239	PF01753	0.489
LIG_MYND_1	287	291	PF01753	0.538
LIG_Pex14_2	219	223	PF04695	0.412
LIG_REV1ctd_RIR_1	140	150	PF16727	0.391
LIG_SH2_CRK	334	338	PF00017	0.589
LIG_SH2_CRK	352	356	PF00017	0.620
LIG_SH2_CRK	73	77	PF00017	0.444
LIG_SH2_NCK_1	320	324	PF00017	0.536
LIG_SH2_SRC	252	255	PF00017	0.655
LIG_SH2_SRC	334	337	PF00017	0.595
LIG_SH2_SRC	352	355	PF00017	0.619
LIG_SH2_STAT3	254	257	PF00017	0.637
LIG_SH2_STAT5	149	152	PF00017	0.420
LIG_SH3_1	74	80	PF00018	0.446
LIG_SH3_3	223	229	PF00018	0.480
LIG_SH3_3	232	238	PF00018	0.536
LIG_SH3_3	240	246	PF00018	0.578
LIG_SH3_3	266	272	PF00018	0.568
LIG_SH3_3	273	279	PF00018	0.594
LIG_SH3_3	288	294	PF00018	0.635
LIG_SH3_3	295	301	PF00018	0.587
LIG_SH3_3	302	308	PF00018	0.783
LIG_SH3_3	74	80	PF00018	0.446
LIG_TRAF2_1	100	103	PF00917	0.416
LIG_TRAF2_1	25	28	PF00917	0.475
LIG_UBA3_1	58	64	PF00899	0.317
LIG_WRC_WIRS_1	116	121	PF05994	0.454
LIG_WRC_WIRS_1	208	213	PF05994	0.392
MOD_CDC14_SPxK_1	153	156	PF00782	0.485
MOD_CDK_SPxK_1	150	156	PF00069	0.466
MOD_CK1_1	200	206	PF00069	0.383
MOD_CK1_1	255	261	PF00069	0.743
MOD_CK1_1	282	288	PF00069	0.716
MOD_CK2_1	11	17	PF00069	0.478
MOD_CK2_1	207	213	PF00069	0.387
MOD_CK2_1	22	28	PF00069	0.502
MOD_CK2_1	309	315	PF00069	0.643
MOD_CK2_1	40	46	PF00069	0.452
MOD_CK2_1	97	103	PF00069	0.406
MOD_GlcNHglycan	191	194	PF01048	0.459
MOD_GSK3_1	197	204	PF00069	0.379
MOD_GSK3_1	213	220	PF00069	0.421
MOD_GSK3_1	279	286	PF00069	0.756
MOD_GSK3_1	29	36	PF00069	0.411
MOD_GSK3_1	342	349	PF00069	0.673
MOD_N-GLC_1	346	351	PF02516	0.617
MOD_NEK2_1	115	120	PF00069	0.376
MOD_NEK2_1	142	147	PF00069	0.470
MOD_NEK2_1	189	194	PF00069	0.455
MOD_NEK2_1	219	224	PF00069	0.422
MOD_NEK2_1	62	67	PF00069	0.417
MOD_NEK2_1	97	102	PF00069	0.397
MOD_PIKK_1	217	223	PF00454	0.413
MOD_PIKK_1	253	259	PF00454	0.609
MOD_PIKK_1	9	15	PF00454	0.467
MOD_PIKK_1	98	104	PF00454	0.410
MOD_PKA_1	9	15	PF00069	0.467
MOD_PKA_2	176	182	PF00069	0.386
MOD_PKA_2	29	35	PF00069	0.511
MOD_PKA_2	8	14	PF00069	0.466
MOD_Plk_1	156	162	PF00069	0.457
MOD_Plk_1	197	203	PF00069	0.382
MOD_Plk_4	207	213	PF00069	0.387
MOD_ProDKin_1	150	156	PF00069	0.466
MOD_ProDKin_1	22	28	PF00069	0.614
MOD_ProDKin_1	247	253	PF00069	0.505
MOD_ProDKin_1	268	274	PF00069	0.622
MOD_ProDKin_1	283	289	PF00069	0.590
MOD_ProDKin_1	301	307	PF00069	0.620
MOD_ProDKin_1	309	315	PF00069	0.660
MOD_SUMO_rev_2	68	76	PF00179	0.430
TRG_DiLeu_BaLyEn_6	284	289	PF01217	0.566
TRG_ENDOCYTIC_2	140	143	PF00928	0.381
TRG_ENDOCYTIC_2	73	76	PF00928	0.437
TRG_NES_CRM1_1	85	99	PF08389	0.393
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.414
TRG_Pf-PMV_PEXEL_1	84	88	PF00026	0.406

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P436	Leptomonas seymouri	60%	95%
A0A3Q8IG34	Leishmania donovani	89%	99%
A4HIS0	Leishmania braziliensis	75%	95%
A4I616	Leishmania infantum	89%	99%
E9B1A7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%