Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q6U9_LEIMA

TriTrypDb:

LmjF.30.3400 , LMJLV39_300042800 , LMJSD75_300042000

Length:

234

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6U9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6U9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	193	195	PF00675	0.640
CLV_NRD_NRD_1	59	61	PF00675	0.509
CLV_NRD_NRD_1	63	65	PF00675	0.541
CLV_PCSK_KEX2_1	193	195	PF00082	0.640
CLV_PCSK_KEX2_1	59	61	PF00082	0.488
CLV_PCSK_KEX2_1	63	65	PF00082	0.515
CLV_PCSK_PC7_1	189	195	PF00082	0.610
CLV_PCSK_PC7_1	59	65	PF00082	0.511
CLV_PCSK_SKI1_1	110	114	PF00082	0.551
CLV_PCSK_SKI1_1	59	63	PF00082	0.522
CLV_Separin_Metazoa	56	60	PF03568	0.503
DEG_Nend_UBRbox_1	1	4	PF02207	0.515
DOC_CYCLIN_RxL_1	105	114	PF00134	0.560
DOC_CYCLIN_yCln2_LP_2	62	68	PF00134	0.640
DOC_MAPK_gen_1	105	113	PF00069	0.565
DOC_MAPK_gen_1	59	68	PF00069	0.553
DOC_MAPK_MEF2A_6	105	113	PF00069	0.565
DOC_PP1_RVXF_1	62	69	PF00149	0.600
DOC_PP2B_LxvP_1	88	91	PF13499	0.661
DOC_PP4_FxxP_1	68	71	PF00568	0.554
DOC_USP7_MATH_1	142	146	PF00917	0.729
DOC_USP7_MATH_1	168	172	PF00917	0.468
DOC_USP7_MATH_1	20	24	PF00917	0.427
DOC_WW_Pin1_4	16	21	PF00397	0.544
DOC_WW_Pin1_4	31	36	PF00397	0.352
LIG_14-3-3_CanoR_1	25	29	PF00244	0.626
LIG_Actin_WH2_2	175	191	PF00022	0.555
LIG_APCC_ABBA_1	1	6	PF00400	0.601
LIG_APCC_ABBA_1	51	56	PF00400	0.495
LIG_FHA_1	153	159	PF00498	0.674
LIG_FHA_1	16	22	PF00498	0.625
LIG_LIR_Apic_2	31	35	PF02991	0.544
LIG_LIR_Gen_1	49	58	PF02991	0.500
LIG_LIR_Gen_1	6	16	PF02991	0.493
LIG_LIR_Nem_3	225	230	PF02991	0.609
LIG_LIR_Nem_3	49	54	PF02991	0.506
LIG_LIR_Nem_3	6	12	PF02991	0.481
LIG_NRBOX	57	63	PF00104	0.509
LIG_PTB_Apo_2	173	180	PF02174	0.624
LIG_SH2_CRK	100	104	PF00017	0.605
LIG_SH2_NCK_1	100	104	PF00017	0.605
LIG_SH2_NCK_1	32	36	PF00017	0.530
LIG_SH2_SRC	45	48	PF00017	0.573
LIG_SH2_STAT5	197	200	PF00017	0.574
LIG_SH2_STAT5	45	48	PF00017	0.601
LIG_SH2_STAT5	89	92	PF00017	0.587
LIG_SH3_3	177	183	PF00018	0.723
LIG_TRAF2_1	8	11	PF00917	0.514
LIG_UBA3_1	106	110	PF00899	0.563
LIG_WRC_WIRS_1	21	26	PF05994	0.557
LIG_WW_3	102	106	PF00397	0.619
MOD_CK1_1	145	151	PF00069	0.683
MOD_CK1_1	23	29	PF00069	0.634
MOD_CK2_1	159	165	PF00069	0.578
MOD_CK2_1	41	47	PF00069	0.473
MOD_GlcNHglycan	84	88	PF01048	0.581
MOD_GSK3_1	16	23	PF00069	0.586
MOD_GSK3_1	24	31	PF00069	0.497
MOD_N-GLC_1	145	150	PF02516	0.682
MOD_N-GLC_1	16	21	PF02516	0.544
MOD_N-GLC_2	50	52	PF02516	0.374
MOD_NEK2_1	111	116	PF00069	0.566
MOD_NEK2_1	24	29	PF00069	0.549
MOD_NEK2_1	83	88	PF00069	0.771
MOD_NEK2_2	20	25	PF00069	0.547
MOD_PKA_2	217	223	PF00069	0.721
MOD_PKA_2	24	30	PF00069	0.625
MOD_Plk_1	41	47	PF00069	0.522
MOD_Plk_1	83	89	PF00069	0.656
MOD_Plk_4	41	47	PF00069	0.556
MOD_Plk_4	69	75	PF00069	0.515
MOD_ProDKin_1	16	22	PF00069	0.547
MOD_ProDKin_1	31	37	PF00069	0.348
TRG_DiLeu_BaEn_1	225	230	PF01217	0.656
TRG_DiLeu_BaLyEn_6	102	107	PF01217	0.605
TRG_DiLeu_BaLyEn_6	124	129	PF01217	0.565
TRG_DiLeu_BaLyEn_6	57	62	PF01217	0.476
TRG_ENDOCYTIC_2	9	12	PF00928	0.487
TRG_ENDOCYTIC_2	99	102	PF00928	0.647
TRG_ER_diArg_1	58	60	PF00400	0.490
TRG_ER_diArg_1	62	64	PF00400	0.529

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2I1	Leptomonas seymouri	59%	100%
A0A3Q8IJQ2	Leishmania donovani	90%	100%
A4HIS8	Leishmania braziliensis	74%	100%
A4I630	Leishmania infantum	91%	100%
E9B1B5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%