Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q6P2_LEIMA

TriTrypDb:

LmjF.31.0220 , LMJLV39_310007400 , LMJSD75_310007400

Length:

207

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6P2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6P2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	4	8	PF00656	0.702
CLV_C14_Caspase3-7	58	62	PF00656	0.763
CLV_NRD_NRD_1	128	130	PF00675	0.678
CLV_NRD_NRD_1	165	167	PF00675	0.532
CLV_PCSK_KEX2_1	128	130	PF00082	0.678
CLV_PCSK_KEX2_1	165	167	PF00082	0.532
CLV_PCSK_SKI1_1	141	145	PF00082	0.685
CLV_PCSK_SKI1_1	165	169	PF00082	0.611
DEG_Nend_UBRbox_2	1	3	PF02207	0.813
DOC_CKS1_1	199	204	PF01111	0.676
DOC_USP7_MATH_1	167	171	PF00917	0.433
DOC_USP7_MATH_1	186	190	PF00917	0.709
DOC_USP7_MATH_1	40	44	PF00917	0.692
DOC_WW_Pin1_4	198	203	PF00397	0.665
LIG_14-3-3_CanoR_1	165	170	PF00244	0.506
LIG_Actin_WH2_2	150	167	PF00022	0.651
LIG_EVH1_1	98	102	PF00568	0.759
LIG_FHA_1	115	121	PF00498	0.643
LIG_FHA_1	146	152	PF00498	0.664
LIG_FHA_2	166	172	PF00498	0.589
LIG_FHA_2	39	45	PF00498	0.758
LIG_LIR_Gen_1	119	127	PF02991	0.469
LIG_LIR_Nem_3	119	124	PF02991	0.574
LIG_MYND_1	101	105	PF01753	0.761
LIG_NRP_CendR_1	206	207	PF00754	0.786
LIG_SH2_CRK	121	125	PF00017	0.601
LIG_SH3_1	98	104	PF00018	0.766
LIG_SH3_3	103	109	PF00018	0.630
LIG_SH3_3	177	183	PF00018	0.709
LIG_SH3_3	185	191	PF00018	0.709
LIG_SH3_3	96	102	PF00018	0.765
LIG_TRAF2_1	66	69	PF00917	0.691
LIG_TRAF2_1	89	92	PF00917	0.715
LIG_TRFH_1	98	102	PF08558	0.766
LIG_WW_2	101	104	PF00397	0.764
MOD_CK1_1	189	195	PF00069	0.696
MOD_CK2_1	24	30	PF00069	0.831
MOD_CK2_1	86	92	PF00069	0.715
MOD_GlcNHglycan	203	206	PF01048	0.518
MOD_GSK3_1	189	196	PF00069	0.694
MOD_GSK3_1	38	45	PF00069	0.816
MOD_GSK3_1	46	53	PF00069	0.713
MOD_PKA_1	165	171	PF00069	0.611
MOD_PKA_2	165	171	PF00069	0.624
MOD_PKA_2	186	192	PF00069	0.705
MOD_Plk_1	38	44	PF00069	0.692
MOD_Plk_4	119	125	PF00069	0.578
MOD_Plk_4	193	199	PF00069	0.572
MOD_ProDKin_1	198	204	PF00069	0.670
TRG_ENDOCYTIC_2	121	124	PF00928	0.591
TRG_ER_diArg_1	127	129	PF00400	0.676
TRG_ER_diArg_1	164	166	PF00400	0.524

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IIB3	Leishmania donovani	95%	100%
A4HIZ7	Leishmania braziliensis	71%	100%
A4I6B4	Leishmania infantum	96%	100%
E9B1H0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
E9B1H2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	88%