cGMP-dependent protein kinase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q6L4_LEIMA

TriTrypDb:

LmjF.31.0490 , LMJLV39_310010400 , LMJSD75_310010100

Length:

822

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

Q4Q6L4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6L4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	196	200	PF00656	0.583
CLV_C14_Caspase3-7	457	461	PF00656	0.716
CLV_C14_Caspase3-7	643	647	PF00656	0.501
CLV_C14_Caspase3-7	734	738	PF00656	0.711
CLV_C14_Caspase3-7	81	85	PF00656	0.831
CLV_NRD_NRD_1	104	106	PF00675	0.637
CLV_NRD_NRD_1	139	141	PF00675	0.502
CLV_NRD_NRD_1	485	487	PF00675	0.762
CLV_NRD_NRD_1	517	519	PF00675	0.581
CLV_PCSK_FUR_1	810	814	PF00082	0.506

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8T1	Leptomonas seymouri	42%	100%
A0A3R7KL00	Trypanosoma rangeli	24%	76%
A0A3S7X491	Leishmania donovani	88%	100%
A4HJ27	Leishmania braziliensis	64%	97%
A4I6E9	Leishmania infantum	88%	100%
E9B1J9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%

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