Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q6I1_LEIMA

TriTrypDb:

LmjF.31.0820 , LMJLV39_310013900 , LMJSD75_310013600

Length:

248

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6I1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6I1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	76	80	PF00656	0.604
CLV_NRD_NRD_1	114	116	PF00675	0.724
CLV_NRD_NRD_1	129	131	PF00675	0.408
CLV_NRD_NRD_1	168	170	PF00675	0.416
CLV_NRD_NRD_1	226	228	PF00675	0.492
CLV_PCSK_KEX2_1	114	116	PF00082	0.724
CLV_PCSK_KEX2_1	168	170	PF00082	0.416
CLV_PCSK_KEX2_1	228	230	PF00082	0.492
CLV_PCSK_PC1ET2_1	228	230	PF00082	0.492
CLV_PCSK_PC7_1	164	170	PF00082	0.405
CLV_PCSK_SKI1_1	17	21	PF00082	0.552
CLV_PCSK_SKI1_1	91	95	PF00082	0.583
DEG_Nend_Nbox_1	1	3	PF02207	0.532
DOC_CYCLIN_RxL_1	88	96	PF00134	0.583
DOC_MAPK_gen_1	130	138	PF00069	0.487
DOC_PP4_FxxP_1	150	153	PF00568	0.465
DOC_USP7_MATH_1	12	16	PF00917	0.753
DOC_USP7_MATH_1	243	247	PF00917	0.538
DOC_USP7_MATH_1	56	60	PF00917	0.582
LIG_14-3-3_CanoR_1	239	243	PF00244	0.519
LIG_BIR_III_4	55	59	PF00653	0.582
LIG_FHA_1	239	245	PF00498	0.703
LIG_FHA_1	72	78	PF00498	0.588
LIG_FHA_2	66	72	PF00498	0.719
LIG_LIR_Apic_2	148	153	PF02991	0.450
LIG_LIR_Apic_2	238	243	PF02991	0.554
LIG_LIR_Nem_3	18	23	PF02991	0.721
LIG_PCNA_PIPBox_1	182	191	PF02747	0.435
LIG_PCNA_yPIPBox_3	181	189	PF02747	0.442
LIG_Pex14_2	146	150	PF04695	0.442
LIG_SH2_CRK	186	190	PF00017	0.414
LIG_SH2_STAT3	242	245	PF00017	0.478
LIG_SH2_STAT5	125	128	PF00017	0.560
LIG_SH2_STAT5	170	173	PF00017	0.452
LIG_SH3_3	21	27	PF00018	0.633
LIG_SH3_3	59	65	PF00018	0.604
LIG_TRAF2_1	230	233	PF00917	0.509
LIG_WRC_WIRS_1	125	130	PF05994	0.479
MOD_CK1_1	15	21	PF00069	0.624
MOD_CK1_1	238	244	PF00069	0.613
MOD_CK2_1	65	71	PF00069	0.723
MOD_GlcNHglycan	116	119	PF01048	0.567
MOD_GlcNHglycan	14	17	PF01048	0.554
MOD_GlcNHglycan	189	192	PF01048	0.350
MOD_GlcNHglycan	33	37	PF01048	0.574
MOD_GlcNHglycan	4	7	PF01048	0.658
MOD_GlcNHglycan	9	13	PF01048	0.684
MOD_GSK3_1	8	15	PF00069	0.698
MOD_NEK2_1	1	6	PF00069	0.574
MOD_NEK2_1	116	121	PF00069	0.654
MOD_NEK2_1	129	134	PF00069	0.371
MOD_PK_1	40	46	PF00069	0.676
MOD_PKA_1	114	120	PF00069	0.568
MOD_PKA_2	114	120	PF00069	0.718
MOD_PKA_2	129	135	PF00069	0.423
MOD_PKA_2	238	244	PF00069	0.517
MOD_Plk_1	8	14	PF00069	0.531
MOD_Plk_4	124	130	PF00069	0.486
MOD_Plk_4	145	151	PF00069	0.459
MOD_SUMO_rev_2	224	230	PF00179	0.468
TRG_DiLeu_BaEn_1	210	215	PF01217	0.420
TRG_DiLeu_BaEn_1	88	93	PF01217	0.507
TRG_DiLeu_LyEn_5	88	93	PF01217	0.507
TRG_ENDOCYTIC_2	125	128	PF00928	0.560
TRG_ENDOCYTIC_2	147	150	PF00928	0.552
TRG_ENDOCYTIC_2	186	189	PF00928	0.411
TRG_ER_diArg_1	113	115	PF00400	0.713
TRG_ER_diArg_1	167	169	PF00400	0.406
TRG_Pf-PMV_PEXEL_1	91	96	PF00026	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICF7	Leishmania donovani	88%	97%
A4I6H6	Leishmania infantum	88%	97%